Clinical trials: Generative Artificial Intelligence
Nursing Education, Simulation-Based Learning
Effects of Concept Mapping and AI Dialogue on Flow and Learning Outcomes in Simulation-Based Learning
This mixed-methods educational study evaluates the integration of concept mapping and artificial intelligence (AI)-supported dialogue into simulation-based learning for nursing students.
- Trial name
- NCT07748897
- Testing
- ChatGPT-Assisted Preparation for Pediatric Nursing Simulation, Standard Preparation for Pediatric Nursing Simulation
- Where
- Taiwan
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Medical Education, Generative Artificial Intelligence
Teaching Medical Students to Verify AI-Generated Citation Hallucinations
Generative artificial intelligence (GenAI) tools are increasingly used by medical students for literature searching, scientific writing, and research. However, AI-generated citations may contain errors.
- Trial name
- SARA (NCT07844746)
- Testing
- SARA Citation-Verification Training, Responsible GenAI Education Intervention Description
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam Medical College
Arterial Blood Gas Analysis
Expert-Validated ChatGPT Support for Arterial Blood Gas Interpretation
This randomized controlled study evaluated whether expert-validated ChatGPT support improved arterial blood gas (ABG) interpretation performance among early-career non-specialist physicians.
- Trial name
- ABG-AI RCT (NCT07849452)
- Testing
- Expert-Validated ChatGPT Support
- Where
- Turkey (Türkiye)
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Quality Improvement
An Evaluation of Epic EHR AI Outpatient Chart Summarization
This is a RCT of 284 outpatient physicians at a large academic health system, randomized 1:1 to an electronic health record (EHR) produced generative AI outpatient chart summarization tool or a usual-care control group.
- Trial name
- NCT07438743
- Testing
- GenAI Chart Summarization
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- University of California, Los Angeles
Substance-related Disorders, Behavior, Addictive
A Study of the Correlation Between the Severity of Substance Use Disorder and the Intensity of Dependence on Generative Artificial Intelligence
This bicentric, cross-sectional observational study conducted in France evaluates the relationship between substance use disorder (SUD) severity and generative artificial intelligence dependency among outpatients treated in…
- Conditions
- Substance-related Disorders, Behavior, Addictive, Artificial Intelligence (AI)
- Trial name
- ADDICT-IA (NCT07819851)
- Testing
- Questionnaire assessment
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cannabis Use Disorder, Anxiety
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
The goal of this clinical trial is to learn if Therabot-CALM (Cannabis, Anxiety, Low Mood) has acceptability among users and could work to improve the symptoms of persons with cannabis use disorder and anxiety and/or depression.
- Conditions
- Cannabis Use Disorder, Anxiety, Depression, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT06920238
- Testing
- Therabot-CALM
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Trustees of Dartmouth College
Medical Education
AI-Generated and Rule-Based Individualized Feedback for Medical Students' Nephrology Learning
Medical education increasingly emphasizes individualized learning and formative assessment; however, providing timely and personalized feedback to students remains challenging because of limited faculty resources.
- Trial name
- AIFB-NR (NCT07871526)
- Testing
- AI-Generated Individualized Feedback, Rule-Based Individualized Feedback, No Individualized Feedback
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Dou Fulin
Endodontic Diseases, Clinical Communication
Generative AI-Based Immersive Training for Endodontic Risk Disclosure and Informed Consent Among Dental Students
The objective of this prospective, parallel-group, 1:1 randomized controlled trial is to evaluate the effectiveness of a generative artificial intelligence (AI)-based immersive training program, utilizing the Gemini platform, in…
- Conditions
- Endodontic Diseases, Clinical Communication, Informed Consent
- Trial name
- GAI-ENDORDIC (NCT07731867)
- Testing
- Generative AI-Based Immersive Training, Conventional Case-Based Learning
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Accuracy of Artificial Intelligence in Fixed Dental Prosthesis Design
Artificial Intelligence Versus Conventional Digital Design for Fixed Dental Prosthesis
This in vitro study aims to evaluate the accuracy of an Artificial Intelligence (AI)-based automatic design system for fixed dental prosthesis (FDP) compared with conventional computer-aided design (CAD) software.
- Trial name
- NCT07432165
- Testing
- Conventional CAD-Based Fixed Dental Prosthesis Design, Artificial Intelligence-Based Fixed Dental Prosthesis Design
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- October University for Modern Sciences and Arts
Prostate Cancer (Adenocarcinoma), Bladder Cancer
Enhancing Readability of Lay Abstracts and Summaries for Medical Knowledge Using Generative Artificial Intelligence (BRIDGE AI 3)
This trial tests if AI can help make medical info clear and readable. Many patients struggle to find medical informations that easy to read and understand from verified medical sources.
- Conditions
- Prostate Cancer (Adenocarcinoma), Bladder Cancer, Kidney Cancers, Testis Cancer
- Trial name
- NCT07568444
- Testing
- Pub2Post
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Hypertansion
Generative AI-Supported Personalized Education Compared With Printed Material for Adults With Hypertension
This study evaluates whether generative artificial intelligence-supported personalized education can improve hypertension knowledge and medication adherence in adults with hypertension compared with standard printed educational…
- Trial name
- GenAI-HYPER (NCT07776834)
- Testing
- Standard Hypertension Education, Generative AI-Supported Personalized Hypertension Education
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Akdeniz University
Dental Prosthesis
Artificial Intelligence Designed Single Tooth Dental Prostheses
Tooth loss is common and as consequence deteriorate patient's health and quality-of-life. Dental prostheses aim to restore patients' appearance and functions by replacement of missing teeth.
- Trial name
- NCT05056948
- Testing
- artificial intelligence (AI) computer assisted design (CAD)
- Where
- Hong Kong
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Generalized Anxiety, Fear of Failure
Optimization of Imagery Rescripting Research Using Generative Artificial Intelligence
This pilot randomized controlled trial will investigate the feasibility and effectiveness of using generative artificial intelligence to create personalized therapeutic scripts for imagery rescripting (ImRs).
- Conditions
- Generalized Anxiety, Fear of Failure, Rumination
- Trial name
- FRBN (NCT07189715)
- Testing
- Imagery Rescripting Intervention (AI-Generated)
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Shared Decision Making, Health Literacy
Designing a Large Language Model Architecture for Shared Decision Making and Informed Intentions
This study investigates a novel, agentic Large Language Model (LLM) architecture designed to facilitate Shared Decision-Making (SDM) in healthcare.
- Conditions
- Shared Decision Making, Health Literacy, Patient Participation, Artificial Intelligence
- Trial name
- DEONCAI3-1 (NCT07827924)
- Testing
- Agentic LLM Chatbot, Usual Care LLM Chatbot, IQWiG Standard Brochure
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Harding Center for Risk Literacy
Lymphoma, Multiple Myeloma
An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers
The goal of this study is to evaluate the feasibility and preliminary efficacy of an artificial intelligence (AI)-generated personalized question prompt list (a list of suggested questions to ask during outpatient appointments)…
- Trial name
- NCT07226934
- Testing
- GPT-QPL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Cognitive Change, Well-Being, Psychological
Impact of GPT Use on Essay Writing Performance and Cognitive Abilities
The goal of this randomized controlled lab experiment is to examine if using generated artificial intelligence (AI) technology will affect people's academic performance and cognitive abilities in the context of analytical writing…
- Trial name
- NCT06511102
- Testing
- GPT Support
- Where
- Germany
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Generative Artificial Intelligence, Creative Thinking
The Effect of Artificial Intelligence Supported Morphological Analysis on Problem Solving and Creative Thinking Disposition
It will be conducted as a two-group, pretest-posttest, randomized controlled study to determine the effect of generative artificial intelligence-supported morphological analysis on nursing students' problem solving skills and…
- Conditions
- Generative Artificial Intelligence, Creative Thinking, Problem Solving, Morphological Analysis and Classification
- Trial name
- NCT07018973
- Testing
- GAISMA, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Gazi University
Creativity
The Creative Team Member: A Study of the Influence of AI Integration Timing on Brainstorming and Ideation
This study aims to examine how the timing of artificial intelligence (AI) integration during group brainstorming activities affects the creativity and ideation of participants.
- Trial name
- NCT07693803
- Testing
- Artificial Intelligence First (Early Integration), Artificial Intelligence Last (Late Integration)
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- McMaster University
Clinical Reasoning in Nursing Education, Virtual Simulation
MAGICS - Multi-Agent Generative AI in Clinical Simulation for Clinical Deterioration Training
This study compares the effectiveness of a Generative AI-integrated blended simulation programme and high-fidelity simulation alone on nursing students' clinical reasoning and learning experience during deterioration training
- Conditions
- Clinical Reasoning in Nursing Education, Virtual Simulation, Artificial Intelligence in Education, Deterioration, Clinical
- Trial name
- MAGICS (NCT07872735)
- Testing
- Generative AI-integrated Blended Simulation, High Fidelity Simulation
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Anterior Segment Diseases
Multimodal Deep Learning Model for Multi-task Diagnosis and Triage Suggestions of Ophthalmic Diseases
Accurate and comprehensive interpretation of anterior segment diseases from slit-lamp and smartphone photographs remains a clinical challenge due to the limited specificity and structure of existing Artificial Intelligence tools.
- Trial name
- NCT07447973
- Testing
- Multimodal Vision-language Model Diagnosis
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital