Clinical trials: Gingival Condition
Saliva Altered, Plaque
Xylitol Chewable Tablets Versus Xylitol Chewing Gum in Geriatric Bedridden Patients
This study will be conducted to evaluate the effectiveness of using dissolving Xylitol chewable tablets versus xylitol chewing gum with bedridden geriatric patients in increasing salivary pH and decreasing bacterial count in both…
- Trial name
- NCT03877705
- Testing
- Listerine ready tabs
- Where
- Egypt
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Bleeding, Von Willebrand Diseases
Gingival Bleeding and Von Willebrand Disease Typ 2 and 3
Von Willebrand disease (VWD) is the most common inherent bleeding disorder resulting in prolonged bleeding time. Gingival bleeding is a frequently reported symptom of VWD.
- Trial name
- NCT03078595
- Where
- 2 sites in Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Goethe University
Periodontitis
Effects of PRF and i-PRF on Clinical and Biochemical Parameters in Non-Surgical Periodontal Therapy
The goal of this clinical trial is to learn if adding platelet-rich fibrin (PRF) or injectable platelet-rich fibrin (i-PRF), obtained from the participant's own blood, to standard non-surgical periodontal treatment helps improve…
- Trial name
- PRF-NSPT (NCT07525531)
- Testing
- Non-surgical periodontal therapy (NSPT), Platelet-rich fibrin (PRF), Injectable platelet-rich fibrin (i-PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Gingival Recession, Tooth Abrasion
Treatment of Gingival Recession-type Defects Using Different Restorative Materials
Background: The aim of this study was to evaluate the treatment of multiple gingival recessions associated with non-carious cervical lesions (NCCL) using a modified coronally advanced flap in combination with a sub-epithelial…
- Trial name
- NCT02788266
- Testing
- connective tissue graft+composite resin, connective tissue graft+ glass ionomer, connective tissue graft+giomer
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Gazi University
Periodontitis, Smoking
SMOKING AND GINGIVAL CREVICULAR FLUID MFN1 AND NLRP3 LEVELS IN PERIODONTAL HEALTH AND PERIODONTITIS
This observational study aims to examine the relationship between cigarette smoking and the levels of two proteins, mitofusin-1 (MFN1) and NLRP3, in the fluid found between the teeth and gums.
- Trial name
- NCT07826728
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Gingivitis
Efficacy of the Addition of a Power Interdental Device to an Electric Toothbrush on Gingival Health.
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04003298
- Testing
- Electric toothbrush, Control
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Mothers, Cesarean Section Complications
The Effect of Chewing Gum After Cesarean Section on Gastrointestinal System Functions, Pain and Sleep Quality
The study will be conducted on mothers who had planned cesarean section.After the birth, the information about the surgery in the personal information form will be completed.
- Trial name
- NCT05945095
- Testing
- Gum chewing group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Artvin Coruh University
Smoking, Periodontitis
The Effect of Smoking and Non-surgical Periodontal Treatment on Gingival Crevicular Fluid Cyclophilin A and EMMPRIN Levels
This study aimed to investigate the effect of smoking and non-surgical periodontal treatment on gingival crevicular fluid CyPA and EMMPRIN levels in patients with periodontitis.
- Conditions
- Smoking, Periodontitis, Non-surgical Periodontal Treatment
- Trial name
- NCT04430764
- Testing
- non-surgical periodontal treatment
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ege University
Gingivitis
Efficacy of Oil Pulling Therapy on Supragingival Plaque Growth
Oil pulling is a method based on Ayurvedic medicine which aims to obtain local and systemic benefits by swirling oils in the oral cavity for a period of 15 minutes, before spitting it out.12 Although the exact mechanism of action…
- Trial name
- NCT03962777
- Testing
- chlorhexidine, oil pulling
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baskent University
Hyperemesis Gravidarum
The Effect of Mint Flavored Chewing Gum on Hyperemesis Gravidarum Nausea Vomiting Severity, Coping With Stress and Anxiety Level in Pregnants With Hyperemesis Gravidarum
In the research planned as a randomized controlled study, the experimental groups will be administered routine hyperemesis gravidarum (HG) treatment as well as chewing mint-flavored gum, while the control group will only receive…
- Trial name
- NCT06266819
- Testing
- chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ordu University
Periodontal Diseases
Clinical and Microbiological Evaluation Of The Efficacy Of Herbal Mouthwashes in Gingivitis
Plaque-induced gingivitis is a clinical condition that appears to cause persistent inflammation in gingiva. It is a preliminary cause to periodontitis but it can be inverted to address the risk of periodontitis development.
- Trial name
- NCT06904742
- Testing
- Tea tree oil, Thyme oil hydrosol, LISTERINE ZERO Alcohol Mouthwash COOL MINT
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Periodontal Disease (Diagnosis), Diabetes Mellitus, Type 2
Possible Role of Gingival Crevicular Fluid Levels of Chemerin and Fibroblast Growth Factor 21 as Biomarkers of Periodontal Disease in Diabetic and Non-diabetic Patients
The current study aims to spot the light on the possible role of gingival crevicular fluid (GCF) level of Chemerin and FGF21 to study their potential role as biomarkers of periodontal disease and to understand their role in the…
- Trial name
- NCT04012983
- Testing
- gingival crevicular fluid level
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Pocket
Gingival Crevicular Fluid Bone Morphogenetic Protein - 2 Release Profile Following the Use of Perforated Membrane
One of the most important elements suggested to be provided through membrane perforations to augment regeneration are cell released growth factors from the overlying periosteal and gingival cells.
- Trial name
- MPM (NCT01860495)
- Testing
- perforated membrane, G2
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Gingivitis
"The Efficacy of Acacia Catechu Mouthrinse as Antiplaque and Antigingivitis Agent in Fixed Orthodontic Appliance Patients.
To study effect of acacia catechu a herbal extract;as antipaque and antigingivitis agent in patients with fixed orthodontic appliances.This study is a double blind randomized controlled trial.
- Trial name
- NCT02154594
- Testing
- Acacia catechu, Chlorhexidine gluconate, Distilled water
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Periodontitis
the Effect of Sub-gingival Irrigation With Ibuprofen 2% Mouthwash in Treatment of Periodontal Diseases.
Aim: Use an ibuprofen mouthwash 2% irrigate subgingival in improving the progression of periodontal diseases can be evaluated. Materials and Methods: 22 patients with chronic periodontitis without any systemic disease who have…
- Trial name
- ibuprofen (NCT02538237)
- Testing
- Ibuprofen 2% mouthwash
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Plaque Induced Gingivitis, Mouth Diseases
Propolis Lozenges Extract and Their Effect on Salivary Biomarkers and on Oral Health Condition in (19_24) Years Old
The goal of this clinical trial is to test the efficiency of using lozenges containing propolis extract over one week to control gingival inflammation and plaque accumulation by measuring the clinical periodontal parameters…
- Conditions
- Plaque Induced Gingivitis, Mouth Diseases, Periodontal Diseases
- Trial name
- NCT06888453
- Testing
- lozenges containing propolis
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Gingivitis, Dental Plaque
A Clinical Comparison of an Experimental Power Brush Compared to a Manual Toothbrush
The objective of the study is to evaluate and compare the efficacy of an experimental power brush to a regular manual brush in the reduction of gingivitis and dental plaque over an 8 week period by using the Modified Gingival…
- Trial name
- NCT03624647
- Testing
- Power toothbrush, Manual toothbrush
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Smoking, Chronic Periodontitis
Apoptotic Changes in Gingiva Caused by Smoking
Smoking is a major environmental risk factor associated with common forms of human chronic periodontitis. The aim of the present study was to evaluate apoptotic tissue alterations and tissue destruction in smoker and non-smoker…
- Trial name
- NCT03631498
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Periodontal Diseases, Periodontitis
Validity of a Self-reported Questionnaire for Periodontal Status in a Saudi Population
This observational study will evaluate the accuracy of a self-reported periodontal questionnaire in adults attending screening appointments in Abha, Saudi Arabia.
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis
- Trial name
- NCT07397104
- Testing
- Self-reported periodontal questionnaire and clinical periodontal examination (reference standard)
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Apical Periodontitis, Inflammatory Markers
The Efficacy of Two Different Irrigation Methods on PGE2, NO and IL-6 Levels
Today, debates about the effectiveness of Passive Ultrasonic Irrigation (PUI) and Sonically Activated Irrigation (SAI) techniques used to increase the success of endodontic treatment in chronic apical periodontitis (AP) are still…
- Trial name
- NCT06629545
- Testing
- irrigation activation with PUI, irrigation with sonic activation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
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