Clinical trials: Gingival Condition
Gingival Recession
CGF and PRF in the Gingival Recessions Treatment
This study hypothesized that CGFs' placement together with CAF may enhance the healing of soft tissues better than use of PRF together with CAF.
- Trial name
- NCT04261634
- Testing
- Concentrated Growth Factor Membrane, Platelet Rich Fibrin
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Gingival Recession, Localized
Clinical Evaluation of Tunneled Coronally Advanced Flap v.s Coronally Advanced Flap With Graft for Gingival Recession
The goal of this clinical trial is to evaluate gingival recession depth reduction using tunneled coronally advanced flap compared to coronally advanced flap, both combined with connective tissue graft in patients with isolated…
- Trial name
- NCT06553677
- Testing
- Tunneled coronal advanced flap with connective tissue graft, Coronally advanced flap with connective tissue graft
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
Apoptic Biomarkers of Periodontal Disease
The goal of this study is to facilitate early diagnosis of gum disease. Proteins associated with cell death will be isolated from gum pockets of diseased and healthy patients and evaluated.
- Trial name
- NCT00569075
- Testing
- collection of gingival crevicular fluid
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Gingivitis, Plaque, Dental
Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis
This placebo-controlled, double-blinded, randomized crossover study evaluates the plaque and gingivitis reducing capacity of Cetylpyridium Chloride (CPC) chewing gum, with mechanical oral hygiene.
- Conditions
- Gingivitis, Plaque, Dental, Periodontal Diseases
- Trial name
- NCT03219840
- Testing
- Cetylpyridinium Chloride (CPC) 0.09% + Xylitol chewing gum, Xylitol only chewing gum
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Gingival Diseases
Collection of Gingival Crevicular Fluid From Periodontitis Patients
To collect GCF (gingival crevicular fluid) samples from diseased patients suffering only from gingivitis and/or periodontitis.
- Trial name
- NCT00763048
- Testing
- Fluoride, Fluoride, triclosan
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
An Efficacy Study of Chlorhexidine Mouthwashes
The aim of this study is to compare subject gingival health after 6 weeks of twice daily use of a non-alcohol or alcohol containing mouthrinse and brushing compared to brushing only.
- Trial name
- NCT01751178
- Testing
- Chlorhexidine Digluconate Mouthwash with Alcohol, Chlorhexidine Digluconate Mouthwash without Alcohol
- Where
- 3 sites in United Kingdom
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gingivitis
Anti-Inflammatory Efficacy of Ginger Containing Dentifrice in the Control of Biofilm Induced Gingivitis
The goal of this clinical trial is to test efficiency of using toothpaste containing (Ginger) over a period of three month to control on gingival inflammation and plaque accumulation through measuring the clinical periodontal…
- Trial name
- NCT05868200
- Testing
- Capitano zenzero toothpaste, Colgate total toothpaste
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Plaque
Effect of Probiotic Toothpaste and Regular Toothpaste on Plaque Levels of Orthodontic Patients
This study is set to determine the improvement in plaque levels utilizing Plaque Index Simplified scores in orthodontic patients using probiotic toothpaste and regular toothpaste.
- Trial name
- NCT06473792
- Testing
- Probiotic Toothpaste
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Kanza Tahir
Gingivitis, Plaque
Effectiveness of the GumChucks® Flossing System Compared to String Floss for Interdental Plaque Removal in Children
This study evaluates the interdental plaque removal efficacy, flossing speed, and reduction in gingival inflammation of a new flossing system (GumChucks®) compared to string floss, and to assess preference between the two…
- Trial name
- NCT04057430
- Testing
- GumChucks, String floss
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gingival Inflammation
Efficacy of Eco-Friendly Toothpaste Tablets Versus Conventional Toothpaste Using PI and GI Index
Objectives: To assess the change in gingival index (GI) and plaque index (PI) when comparing the use of toothpaste tablets to conventional toothpaste.
- Trial name
- NCT05805865
- Testing
- Toothpaste Tablet, Conventional Toothpaste
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Gingival Inflammation
Investigation of the Interplay Between Local Oral Inflammation, Microbiota and Systemic Immune Responses.
This is a clinical research study designed to measure changes in inflammation and the oral microbiome during a phase of good oral hygiene and the absence of oral hygiene.
- Trial name
- ILIMSIR (NCT06966492)
- Testing
- Stannous Fluoride Toothpaste (SnF)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Constipation
Effectiveness of Partially Hydrolyzed Guar Gum in Improving Fecal Characteristics in Long Term Care Facility Residents
Partially hydrolyzed guar gum (PHGG) is a vegetal, water soluble, non-viscous, non-gelling dietary fiber that is derived from guar gum, a water-soluble, viscous, gelling polysaccharide found in the seeds of Cyamopsis…
- Trial name
- NCT05037565
- Testing
- Partially hydrolyzed guar gum
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Periodontitis, Gingivitis
Fractalkine-CX3CR1 Axis in Periodontal Therapy
This study aimed to evaluate gingival crevicular fluid (GCF) levels of fractalkine/CX3CL1 and CX3CR1 in patients with gingivitis and periodontitis before and after non-surgical periodontal therapy.
- Conditions
- Periodontitis, Gingivitis, Inflammation Biomarkers
- Trial name
- NCT07307144
- Testing
- Non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Giresun University
Periodontal Diseases
GCF Levels of Chemokines in Periodontitis
This study aimed to determine CCL19/MIP3beta(β) and CCL20/MIP3alpha(α) in the gingival crevicular fluid (GCF) of the patients with different periodontitis phenotypes.
- Trial name
- NCT06291454
- Testing
- Routine periodontal examination
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ordu University
Gingival Recession, Periodontal Diseases
The Comparison of the Efficacy of Gingival Unit Graft With Connective Tissue Graft in Root Coverage
The purpose of the study is to compare the clinical effectiveness of gingival unit graft (GUG) and connective tissues graft (CTG) in Miller's class I and II gingival recession.
- Trial name
- NCT04637451
- Testing
- Root coverage treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Okan University
Crowding, Tooth
The Effects of Ibuprofen and Laser on Orthodontic Pain
Early orthodontic pain is usually caused by the insertion of elastomeric separators to the mesial and distal of the tooth to be banded in order to create adequate space for proper placement.
- Trial name
- NCT04070001
- Testing
- 400 Mg Ibuprofen, laser application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeşim KAYA
Gingival Inflammation, Dental Plaque Accumulation
Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash
This study evaluates the antiplaque efficacy of a bioflavonoid-based mouthwash compared to a positive control (0.12% chlorhexidine mouthwash).
- Trial name
- NCT07824388
- Testing
- Bioflavonoid mouthwash, Chlorhexidine 0.12% mouthwash
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Recession, Gingival
Root Coverage With Acellular Dermal Matrix and Bovine Derived Osseous
The study will consist of a randomized controlled clinical study trial comparing the results of coronally positioned flap with AlloDerm GBR plus bovine derived xenograft versus coronally positioned tunnel with AlloDerm GBR plus…
- Trial name
- NCT03582995
- Testing
- Flap Surgery for root coverage with Alloderm and xenograft, Tunnel Surgery for root coverage with Alloderm and xenograft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Dental Caries
Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction
This study compared four mouth rinses/chews for their ability to reduce Streptococcus Mutans after usage. The four that were compared were chlorhexidine gluconate (0.12%), sodium fluoride (0.05%), paraffin wax chewing gum (sugar…
- Trial name
- NCT02598778
- Testing
- Chlorhexidine gluconate (0.12%), Sodium Fluoride (0.05%), Paraffin wax chewing gum (sugar-free)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
COVID-19
Complementary Intervention for COVID-19
Boswellia Serrata gum and Licorice extract are two nutritional agents that have pharmacological actions that could support the medical intervention for COVID-19.
- Trial name
- NCT04487964
- Testing
- Licorice extract
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Egyptian Biomedical Research Network
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