Clinical trials: Gingival Condition
Wound Heal, Platelets; Defect
Effects of Platelet Concentrates on Palatal Wound Healing
Platelet concentrates used in palatal wound healing have been reported to accelerate wound healing and reduce postoperative patient discomfort.
- Conditions
- Wound Heal, Platelets; Defect, Periodontal Inflammation, Gingival Recession
- Trial name
- NCT04097509
- Testing
- AFG application on palatinal wound healing, i-PRF application on palatinal wound healing, control
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Inonu University
Gingival Recession
Ubiquinone (Coenzyme Q10) Application After Gingival Recession Coverage
This randomised double blinded clinical trial has the aim to assess the effect of ubiquinone (Coenzyme Q10) on early wound healing following gingival recession coverage.
- Trial name
- NCT04487652
- Testing
- Gingival recession coverage, with CoQ10 spray application
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bern
Gingivitis, Circadian Rhythm Disruption
Circadian Clock Proteins in Gingival Crevicular Fluid of Individuals With and Without Circadian Rhythm Disruption
This prospective cross-sectional clinical study aims to investigate the relationship between circadian rhythm disruption and periodontal inflammation by evaluating circadian clock protein levels, inflammatory (IL-1beta) and…
- Conditions
- Gingivitis, Circadian Rhythm Disruption, Periodontal Inflammation, Circadian Rhythm Sleep Disorder, Shift Work Type
- Trial name
- Nursma-CIRC-HG (NCT07592052)
- Testing
- Standard Periodontal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Inonu University
Biofilm Removal, Gingival Abrasion
Capacity of Biofilm Removal and Gingival Abrasion After Utilization Medium and Soft Toothbrushes
This study compared the removal of dental biofilm between soft and medium toothbrushes. The patients refrained from performing mechanical or chemical plaque control for 96 hours to allow dental biofilm accumulation on the tooth…
- Trial name
- NCT01125007
- Testing
- Two kind toothbrushes
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Franciscan University Center
Graft Pain, Gingival Recession
MEBO Ointment and Hyaluronic Acid Gel in the Management of Pain After Free Gingival Graft Harvesting
Postoperative pain as well as bleeding are the most common complications after palatal graft harvesting also postsurgical swelling have been reported , Although different agents were used to protect the denuded areas on the…
- Trial name
- NCT03728244
- Testing
- MEBO ointment, Hyaluronic Acid gel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis, Plaque, Dental
Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected Toothbrush
The objective of this clinical research study is to assess plaque and gingivitis reductions of Connected Toothbrush compared to Non-Connected Toothbrush over a six-week clinical study.
- Trial name
- Connected (NCT04221334)
- Testing
- Electric Toothbrush, oral health care application
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontitis
Efficacy of PRF Application on Clinical Parameters and GCF Platelet-derived Growth Factor-BB and Periostin Levels
Determine the efficacy of the non-invasive application of PRF on periodontal clinical parameters(pocket reduction) and the levels of PDGF-BB and Periostin in the gingival crevicular fluid.
- Trial name
- NCT05178771
- Testing
- Platelet rich fibrin
- Where
- Iraq
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Gingival Recession, Bone Loss, Alveolar
Esthetic Outcomes of Single Immediate Implant Placement
A randomized controlled trial of 12-month duration to compare gingival margin location, buccal horizontal ridge dimensions, and interproximal crestal bone levels following two surgical approaches for immediate placement of…
- Trial name
- NCT02435706
- Testing
- Flapless immediate implant placement, Flap assisted immediate implant placement, Implant and temporary crown
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Columbia University
Gingivitis, Plaque
Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque
The purpose of this study is to evaluate the safety and efficacy of experimental mouth rinse formulations compared to a positive control mouth rinse and a hydroalcohol control mouth rinse for the reduction of gingivitis and…
- Trial name
- NCT04921371
- Testing
- Colgate® Cavity Protection Toothpaste, Listerine® Cool Mint®, Concept Curve Winter Series Toothbrush
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Gingivitis and Periodontal Diseases
Evaluation and Correlation of Serum Fetuin-A Levels in Periodontal Health and Disease: A Clinico-biochemical Study
The present clinico-biochemical study was carried out to estimate the levels of Fetuin A and MMP7 in serum of systemically healthy subjects in periodontal health and disease and to evaluate the impact of periodontal…
- Trial name
- NCT04198610
- Testing
- Non surgical periodontal therapy
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Rheumatoid Arthritis, Periodontitis
Prolactin Hormone in Rheumatoid Arthritis Patients With Periodontitis
In this study we will assess the presence of prolactin hormone in the gingival crevicular fluid , and synovial fluid of patient with rheumatoid arthritis and periodontitis
- Trial name
- NCT04279691
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Gingival Recession, Localized
Reconstruction of Deficient Interdental Papilla Using Stem Cells vs Physiological Saline
The goal of this study is to assess the reconstruction of interdental papilla following the injection of UC-MSCs or physiological saline in patients with interdental papilla deficiency.
- Trial name
- NCT06388447
- Testing
- Umbilical cord-mesenchymal stem cells
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Periodontitis
Boron Levels, Oxidative Stress, and Inflammation in Periodontitis
This cross-sectional observational study aims to evaluate the relationship between boron levels and oxidative stress, antioxidant defense, and inflammatory markers in individuals with periodontitis.
- Trial name
- NCT07775378
- Testing
- Biochemical Assessment of Saliva and Gingival Tissue
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Caries, Gingivitis
Interdental Microbiota Among Adolescents
Adolescence remains a period during which tooth decay is still very active. There are few epidemiological studies in adolescents, and the majority of them were young people aged 15 and under.
- Trial name
- MIARC (NCT03700840)
- Testing
- Interdental brushes
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université Montpellier
Gingival Overgrowth
Diode Laser in Gingival Enlargement Related to Orthodontics
Gingival enlargement is one of the most common soft tissue problems associated with fixed orthodontic treatment. The presence of orthodontic appliances impedes oral hygiene measures and alters the oral microbial ecosystem to a…
- Trial name
- NCT01286298
- Testing
- Laser gingivectomy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Gingivitis
Efficacy of the Addition of a Power Interdental Device to an Electric Toothbrush on Gingival Health.
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04003298
- Testing
- Electric toothbrush, Control
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Gingival Recession
Amnion Chorion Membrane in Comparison to Subepithelial Connective Tissue Graft in Gingival Recession Coverage
The present randomized, controlled, parallel-grouped trial included twenty patients (aged 20 to 54 years) suffering from Miller's class I or II gingival recession.
- Trial name
- NCT02656732
- Testing
- amnion chorion allograft membrane, coronally advanced flap with the subepithelial connective tissue graft
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis, Gingivitis
Regulatory T Cell With Related Interleukins in Periodontal Disease Progression
T Regulatory cells which suppressor subset of T cells and related cytokines remain in blood and infiltrates into the tissue under need.
- Trial name
- NCT06135116
- Testing
- Flow Cytometric Detection of Regulatory T Cells and Cytokines analysis by ELISA
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Gingivitis
Efficacy and Safety Study of Interproximal Cleaning Modalities on Oral Health
The purpose of this study is to evaluate the safety and efficacy of tooth and interproximal cleaning modalities with and without chemistry on oral health over 28 days.
- Trial name
- NCT02187016
- Testing
- AirFloss + BreathRx, AirFloss + Listerine, Dental Floss
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Philips Oral Healthcare
Dental Plaque, Gingivitis
A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation
The aim of this 24-week clinical study is to evaluate the ability of an experimental dentifrice containing 0.454 percent (%) weight by weight (w/w) Stannous fluoride (SnF2); to improve gingival health, plaque reduction and…
- Trial name
- NCT07255040
- Testing
- Test Dentifrice, Parodontax Complete Protection, Colgate Cavity Protection
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- HALEON
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