Clinical trials: Gingival Condition
Plaque, Gingivitis
A Clinical Trial to Test the Effect of Marketed Mouth Rinses on Decreasing Plaque and Gum Inflammation
The reduction of existing plaque and gum inflammation will be evaluated using two marketed mouth rinses along with tooth brushing after 21 days of use compared to a placebo mouth rinse.
- Trial name
- NCT02233998
- Testing
- Mouth Rinse 1, Mouth Rinse 2, Mouth Rinse 3
- Where
- Canada
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Gingival Recession
The Comparison of Different Root Coverage Techniques Using the Anatomical Recession Area Approach
The goal of this clinical trial is to compare the effectiveness of two treatments for gingival recession. The main questions it aims to answer are: Which treatment method, Coronally Positioned Flap with Connective Tissue Graft or…
- Trial name
- NCT06272006
- Testing
- Coronally Positioned Flap with Connective Tissue Graft, Modified Coronally Advanced Tunnel with Connective Tissue Graft
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Gingivitis, Probiotics
Effects of Probiotic Ayran on Gingivitis
Objectives: This study investigates the effects of daily consumption of probiotic ayran drink on gingival inflammation and the development of experimental gingivitis.
- Conditions
- Gingivitis, Probiotics, Inflamed Gums
- Trial name
- NCT06437925
- Testing
- probiotic ayran drink
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Gingivitis, Dental Plaque Accumulation
Essential Oils Mouth Rinse and Dental Floss: Efficacy on Interproximal Gingivitis and Dental Plaque Accumulation
It is difficult to obtain patient's compliance with regular interproximal dental hygiene. Dental floss is recognized as an effective procedure to remove dental plaque and prevent gingivitis in the space between teeth, but it is…
- Trial name
- NCT01236963
- Testing
- Essential oils mouthrinse, Dental Floss
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Non-infectious Uveitis, Periodontal Disease
Periodontal Status and Cytokine Levels in Patients With Non-Infectious Uveitis
This cross-sectional observational study aimed to evaluate periodontal clinical parameters and inflammatory cytokine levels in gingival crevicular fluid (GCF), saliva, and serum in patients with non-infectious uveitis (NIU)…
- Trial name
- NIU-PERIO (NCT07480291)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Gingivitis
To Evaluate the Efficacy of Probiotics Toothpastes in Improvement of Gingivitis and Prevention of Periodontal Diseases Via Modulating the Oral Microbiota
Gingivalis is the one of the most common diseases of oral cavity, and affects more than 75% of adult populations worldwide. The present studies demonstrated that the addition of probiotics in toothpastes or mouthwashes could…
- Trial name
- NCT04190485
- Testing
- GMNL-143 Probiotic Toothpastes, GMNL-464 Probiotic Toothpastes
- Where
- Taiwan
- Volunteers
- 47 people
- Sponsor
- GenMont Biotech Incorporation
Gingivitis, Periodontitis
A Clinical and Imaging Study to Evaluate a Novel Dentifrice
There is a need for toothpastes that more effectively remove oral biofilm, inhibit biofilm re-formation and support periodontal health.
- Conditions
- Gingivitis, Periodontitis, Dental Plaque
- Trial name
- NCT02271815
- Testing
- Oral Hygiene
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of California, Irvine
Periodontal Health, Gingivitis
Salivary and GCF Biomarkers in Periodontal Health, Gingivitis and Periodontitis
This observational cross-sectional study aims to compare the levels of irisin, interleukin-6 (IL-6), interleukin-10 (IL-10), and tumor necrosis factor-alpha (TNF-α) in saliva and gingival crevicular fluid (GCF) among individuals…
- Conditions
- Periodontal Health, Gingivitis, Periodontitis
- Trial name
- NCT07881406
- Testing
- Clinical periodontal examination, ELISA-based biomarker analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Periodontitis, Gingivitis
The Effects of DHA on Periodontitis
The purpose of this study is to determine whether docosahexaenoic acid (DHA) is effective in the treatment of periodontitis in adults.
- Conditions
- Periodontitis, Gingivitis, Inflammation
- Trial name
- DAP (NCT01976806)
- Testing
- Aspirin, Docosahexaenoic acid
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Gingival Bleeding, Dental Plaque
Efficacy of Dental Hygiene Aids in Reducing Gingival Bleeding and Plaque Among Orthodontic Patients.
Adult orthodontic patients aged 18-30 were included in a randomised, single-blind clinical research using a split-mouth design at a dental clinic. Both the Waterpik® and the Super-Floss® water flossers are manufactured by Oral-B.
- Trial name
- NCT06554938
- Testing
- water pik, Super floss
- Where
- United Arab Emirates
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ajman University
Gingival Bleeding, Plaque Induced Gingival Disease
Comparative Study to Evaluate the Efficacy of an Alcohol-free Mouthwash Regimen With CPC+Zn, Flossing and Brushing, and an Alcohol-based Mouthwash Regimen With Essential Oils in Reducing Plaque and Gingivitis.
This is a Phase III, randomized, one-center, parallel group, double blinded, clinical study to evaluate the efficacy of an alcohol-free mouthwash containing CPC+Zn as compared to dental flossing and to rising with an essential…
- Conditions
- Gingival Bleeding, Plaque Induced Gingival Disease, Gingival Diseases, Gingivitis and Periodontal Diseases
- Trial name
- PGMWII (NCT06598072)
- Testing
- Mouthwash CPC+Zn+F, Essential oils mouthwash, Dental floss
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Colgate Palmolive
Dental Caries
Delivery of Polyphenols in Gum as an Anti-Caries Agent
The short-term effects of chewing gum containing xylitol and/or blackberry extract on oral microbiota was studied. Fifty healthy adults participated in a randomized, placebo-controlled, cross-over design study.
- Trial name
- BBE (NCT05133557)
- Testing
- Chewing gum containing xylitol and blackberry extract (BBE)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Craig Miller
Inflammation Gum, Cardiac Surgery
Impact of Teeth Extraction on Inflammation Marker's Levels in Patients Who Undergoing Cardiac Surgery
The aim of this study is to examine effects of dental treatments, surgical (extractions) and non-surgical procedures (non-surgical periodontal therapy), on serum levels for PCR, WBCs and PCT in patients needing a dental…
- Trial name
- NCT04626011
- Testing
- Tooth extractions
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- University of Trieste
Electronic Cigarette Use, Plaque Induced Gingivitis
Efficacy of Oral Hygiene Instructions on Proinflammatory Cytokines Among Cigarette Smokers and Individuals Vaping Electronic Cigarettes During Plaque Induced Gingivitis (Clinical Trial)
To evaluate the level of proinflammatory cytokines in individual vaping electronic cigarette in gingivitis patients. Can vaping affects the proinflammatory cytokines level in diseased individuals? Group I: cigarette smoker with…
- Trial name
- NCT06177158
- Testing
- oral hygiene instructions
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Gingivitis
A Clinical Trial to Test the Effect of Experimental Mouth Rinse on Gum Disease
Participants will be given special instructions about taking care of their teeth during the 18 hours before they come to the dentist's office for screening/baseline, 1 week, 2 weeks and 4 weeks.
- Trial name
- NCT02065414
- Testing
- Listerine Advance Gum Defense, Mouth rinse containing Chlorhexidine, Mouth rinse containing 5% Hydroalcohol
- Where
- United Kingdom
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Gingival Recession, Palate; Wound
Comparison of Graft Quality and Patient Morbidity Following Palatal Harvesting.
The purpose of this study is to compare four different connective tissue graft harvesting technique in terms of graft quality and patient post-operative morbidity
- Trial name
- NCT03584906
- Testing
- DGG Harvesting approach, ET harvesting approach, TDT harvesting approach
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- University of Milan
Gingival Recession, Localized, Keratinized Tissue
Er,Cr:YSGG Laser for Deepithelialization in Gingival Recession.
Abstract: Introduction: The deepithelialized free gingival graft (DGG) technique provides high-quality connective tissue grafts (CTGs) with predictable outcomes for recession cov-erage.
- Conditions
- Gingival Recession, Localized, Keratinized Tissue, Gingival Thickness, Pocket Depth
- Trial name
- NCT07064304
- Testing
- Laser Deepithelialization of Free Gingival Graft, Scalpel Deepithelialization of Free Gingival Graft
- Where
- Poland
- Volunteers
- 9 people
- Sponsor
- Wroclaw Medical University
Recession, Gingival
Pinhole Surgical Technique for Root Coverage Using PRF
The current study is a prospective randomised split mouth study to evaluate the effect of Platelet Rich Fibrin as an adjunct to the minimally invasive pinhole surgical technique.
- Trial name
- NCT04202198
- Testing
- A-PRF, pinhole surgical technique only
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Gingival Diseases
Pilot Efficacy Study to Treat Gingivitis
The primary purpose is to demonstrate the efficacy of a prescription mouthrinse in human subjects for treatment of Gingivitis.
- Trial name
- NCT00391547
- Testing
- Frio Oral Rinse
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Biomedical Development Corporation
Relapse, Gingival Recession
RCT for the Effectiveness of 3 Orthodontic Retention Schemes on Post-treatment Stability and Gingival Recession
The present study aims to assess the effectiveness of three different retention schemes used to maintain tooth position after orthodontic treatment with fixed orthodontic appliances (stability) and to evaluate possible…
- Trial name
- OrthRe10tion (NCT02742493)
- Testing
- 0.028 bonded to canines, 0.027 7-strand bonded to all 6, removable Hawley-type
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Athens
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