Clinical trials: Gingival Condition
Bowel Ileus, Flatus
Chewing Gum on Postoperative Ileus in Children
Traditional postoperative care has been challenged recently to improve and speedup recovery (including the return of bowel function) such that patients can be discharged to home more quickly.
- Trial name
- GUM_1 (NCT03666377)
- Testing
- Gum chewing
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Gingival Recession
Clinical Evaluation of Single-stage Advanced Versus Rotated Flaps in the Treatment of Gingival Recessions
BACKGROUND: Several procedures have been reported for the surgical correction of gingival recession (GR), including the laterally positioned flap (LPF) and the coronally advanced flap (CAF), performed as single or two-stage…
- Trial name
- NCT02433912
- Testing
- Test - Laterally positioned flap, Control-Coronally positioned flap, 750 mg paracetamol
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dental Plaque (Diagnosis), Dental Plaque Imaging Methods
Digital Quantification of Dental Plaque Based on Intraoral Scanner Images
This diagnostic validation study aims to develop and validate a digital method for dental biofilm quantification using three-dimensional images obtained by an intraoral scanner.
- Conditions
- Dental Plaque (Diagnosis), Dental Plaque Imaging Methods, Dental Plaque, Gingivitis
- Trial name
- NCT07152314
- Testing
- Digital plaque quantification using intraoral scanner
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Periodontal Disease, Gingival Inflammation and Bleeding
Efficacy of Oral Hygiene Regimens in Patients Undergoing Non-Surgical Periodontal Treatment
The objective of this clinical study is to evaluate the efficacy of multi-component oral hygiene regimens as adjunctive to non-surgical periodontal treatment in patients with stage II periodontitis.
- Trial name
- PEREG (NCT07803484)
- Testing
- Active Oral Hygiene Regimen
- Where
- 2 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- Colgate Palmolive
Gingival Recession
Effect of Hyaluronic Acid on Gingival Recession Treatment
Gingival marginal tissue recession is the displacement of the soft tissue margin apical to the cementoenamel junction (CEJ) with exposure of the root surface.
- Trial name
- NCT04692558
- Testing
- HYALURONIC ACID, coronally advanved flap with connective tissue harvesting
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Gingival Diseases
Analysis of Line-Field Confocal Optical Coherence Tomography (LC-OCT) in Characterization of Gingival Systemic Health, Gingivitis and Periodontitis
The aim of the study is to identify tissue changes among healthy patients, patients with gingivitis and with periodontitis before and after treatment, by analyzing tissues changes through Line-Field Confocal Optical Coherence…
- Trial name
- Perio-LC-OCT (NCT06831487)
- Testing
- Line-Field Confocal Optical Coherence Tomography (LC-OCT)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Catania
Gingivitis and Periodontal Diseases, Periodontitis
Association Between Periodontal Status and the Prevalence of Entamoeba Gingivalis and Trichomonas Tenax
This prospective observational study aims to investigate the prevalence and clinical significance of two oral protozoa, Entamoeba gingivalis and Trichomonas tenax, among patients attending the Bolu Abant İzzet Baysal University…
- Trial name
- NCT07551115
- Testing
- Clinical Periodontal Evaluation, Microscopic Examination of Oral Protozoa
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Gingival Recession, Localized, Tooth Abrasion
Use of a Novel Volume-stable Collagen Matrix (VCMX) in the Treatment of Single Gingival Recession Associated With Non-carious Cervical Lesion Partially Restored
Gingival recessions (GR) are often associated with non-carious cervical lesions (NCCL), resulting, thus, in a combined defect. This mucogingival condition has a different treatment prognosis when compared with a GR without…
- Trial name
- NCT05916716
- Testing
- Restorative procedure, Coronally Advanced Flap (CAF)., Volume-stable collagen matrix (VCMX)
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Recession
Platelet Rich Fibrin vs Sub Epithelial Connective Tissue and Coronally Advanced Flap Alone in Gingival Recession
Gingival thickness plays a key role not only in the etiology but also in the treatment of gingival recessions. a thin marginal tissue lining the hard periodontal tissues seems to be one of the main risk factor for the onset of…
- Trial name
- NCT03712852
- Testing
- PRF+CAF treated patients, SCTG+ CAF treated patients, CAF treated patients
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Hyaluronic Acid, Gingival Recession, Localized
Hyaluronic Acid and Free Gingival Graft Healing
This study aims to evaluate the impact of locally applied hyaluronic acid on free gingival graft wound bed healing and palatal donor site wound healing. Forty subjects will be randomly divided in two separate groups.
- Conditions
- Hyaluronic Acid, Gingival Recession, Localized, Pain, Postoperative
- Trial name
- NCT05990049
- Testing
- Hyadent BG
- Where
- Croatia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Microbiome, Cytokines
Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis
This study is a six-week, double-blind, randomized, parallel-group controlled clinical study. The objective of this study is to evaluate the changes to the oral microbiome, inflammatory mediators, gingival health indices and to…
- Conditions
- Microbiome, Cytokines, Plaque, Gingivitis
- Trial name
- NCT07501455
- Testing
- Distilled Water, Marketed Comparator 1, Marketed Comparator 2
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Excessive Gingival Display, Gingival Diseases
Botulinum Toxin Type A Versus Cross-Linked Hyaluronic Acid Filler Myomodulation for Non-Surgical Management of Excessive Gingival Display
This randomized controlled trial compared the clinical efficacy and patient satisfaction of two non-surgical treatments for excessive gingival display (gummy smile): botulinum toxin type A (BTX-A) and cross-linked hyaluronic acid…
- Conditions
- Excessive Gingival Display, Gingival Diseases, Gummy Smile, Esthetics, Dental
- Trial name
- NCT07715331
- Testing
- Botulinum Toxin Type A (Refinex®), Cross-Linked Hyaluronic Acid Filler (Juvéderm Voluma® with Lidocaine)
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Gingival Recession, Localized
Cyanoacrylate Use in Free Gingival Graft
Present study aims to reveal the effects of cyanoacrylate application at the recipient bed and the donor site in free gingival graft surgery on the healing parameters and patient-based outcomes.
- Trial name
- NCT04854902
- Testing
- Free gingival graft, Cyanoacrylate, Suture
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Biruni University
Periodontitis, Obesity
EVALUATION of GINGIVAL CREVICULAR FLUID and SERUM ASPROSIN LEVELS in OBESE and NORMAL-WEIGHT INDIVIDUALS with PERIODONTITIS
Obesity and periodontitis are chronic inflammatory diseases that share common pathological mechanisms. Asprosin, a novel adipokine discovered in 2016, has not been extensively studied in relation to periodontal tissues.
- Trial name
- NCT06879951
- Testing
- Participants are not assigned an intervention as part of the study.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingivitis
A Randomized, Controlled, Double-blind Clinical Trial of Surinam Cherry Dentifrice With Anti-gingivitis Properties
In the present randomized, controlled, double-blind clinical trial, we investigated the short term clinical efficacy of a dentifrice containing Eugenia uniflora L. ripe fruit extract in preventing gingivitis in children.
- Trial name
- NCT02648139
- Testing
- Dentifrice
- Volunteers
- 50 people
- Sponsor
- Federal University of Paraíba
Periodontitis, Diabetes Mellitus
Endocan Biomarker Level in Gingival Crevicular Fluid in Periodontitis Patients With Type 2 Diabetes Mellitus
Aim of the current study was to evaluate Endocan biomarker level in gingival crevicular fluid of patients with stage 1 or 2 (mild to moderate) periodontitis with controlled type 2 diabetes mellitus (DM) and compare it to that in…
- Trial name
- NCT05667051
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Alexandria University
Gingival Recession, Localized
The Effect Of Using Sticky Bone With Coronally Advanced Flap In Management Of Type 1 Gingival Recession
the main goal of this clinical trial is to evaluate the effect of sticky bone with coronally advanced flap in management of gingival recession in comparison to coronally advanced flap alone
- Trial name
- NCT06871475
- Testing
- sticky bone with coronally advanced flap, coronally advanced flap
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Gingivitis
Effect of Nigella Sativa Toothpaste on Salivary Biomarkers in Patients With Gingivitis
This study evaluated the effects of Nigella sativa toothpaste on salivary inflammatory biomarkers (IL-1β, PGE2, and MMP-8) in Indonesian Army personnel with gingivitis.
- Trial name
- NS-GINGIVITIS (NCT07447349)
- Testing
- Nigella sativa toothpaste
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Airlangga
Gingival Recession
Comparison of Root Coverage of Gingival Recessions
The purpose of this study is to analyze the percentage of root coverage in Miller class I and II gingival recessions using connective tissue graft and collagen matrix with a two years follow-up.
- Trial name
- NCT02980055
- Testing
- collagen matrix, connective tissue graft
- Volunteers
- 46 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Kidney Failure, Chronic
Effects of Gum Arabic Supplementation in Hemodialysis Patients
Gum Arabic is a naturally produced gummy exudate from Acacia Senegal tree. It's a complex polysaccharide with proven prebiotic properties.
- Trial name
- NCT03789708
- Testing
- Gum Arabic
- Where
- Sudan
- Volunteers
- 80 people
- Sponsor
- University of Khartoum
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