Clinical trials: Gingival Graft
Soft Tissue Augmentation, Gingival Recession Localized Moderate
Evaluation of the Effect of Smoking on Palatal Donor Site Tissue Profile in the Success of Connective Tissue Grafts
This single-center prospective clinical study investigates how smoking affects palatal donor site tissue biology and, in turn, the success of connective tissue grafts used in root coverage surgery.
- Conditions
- Soft Tissue Augmentation, Gingival Recession Localized Moderate, Palatal Morphology
- Trial name
- NCT07777185
- Testing
- Coronally Advanced Flap with Subepithelial Connective Tissue Graft (CAF + CTG)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ankara University
Recession, Gingival
Clinical Evaluation of Laterally Closed Tunnel Technique Versus Coronally Advanced Flap Combined With Connective Tissue Graft for the Treatment of Isolated RT2 Gingival Recession
The aim of this study is to evaluate reduction of recession depth using lateral closed tunnel technique versus CAF technique using connective tissue graft in single RT2 gingival recession cases.
- Trial name
- NCT05823415
- Testing
- Laterally Closed Tunnel with CTG, CAF with CTG
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Free Gingival Graft
A-PRF and CGF in Palatal Donor Site Healing
The objective of this study was to compare and evaluate the effects of concentrated growth factor (CGF) and advanced platelet-rich fibrin (A-PRF) clot membranes on palatal epithelial wound healing and postoperative discomfort…
- Trial name
- FGG (NCT07439068)
- Testing
- Advanced platelet-rich fibrin, Concentrated growth factor, Sterile gelatin sponge
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ordu University
Gingival Recession
Titanium-prepared Platelet Rich Fibrin Versus Connective Tissue Graft for Management of Type-2 Gingival Recession
The aim of the study is to evaluate the effectiveness of using titanium prepared platelet rich fibrin with coronally advanced flap in the treatment of type-2 Cairo gingival recession.
- Trial name
- NCT06621433
- Testing
- T-PRF with CAF, SECTG with CAF
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Rizk Beshir
Lack of Keratinized Tissue
Fixation of Free Gingival Graft Using Tissue Tacks vs Criss-cross Sutures
Tissue tacks may improve graft stability but their effect on pain is unclear. The study compares tacks and sutures by measuring pain, stability, healing success, and patient comfort.
- Trial name
- NCT07823374
- Testing
- Criss cross sutures, Tissue tacs
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- October University for Modern Sciences and Arts
Gingival Recession
Single Stage Root Coverage for Gingival Recession With or Without Free Gingival Graft
Background and Objective: Gingival recession accounts for apical migration of the gingival margin resulting in exposure of the cementoenamel junction (CEJ) and root surface.
- Trial name
- NCT03370042
- Testing
- semilunar coronally positioned flap with free gingival graft, semilunar coronally positioned flap alone
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kamineni Institute of Dental Sciences
Palatal Wound Healing, Mucogingival Defects
Active Oxygen Gel Versus Hyaluronic Acid Gel for Palatal Wound Healing After Free Gingival Graft
This randomized controlled clinical trial aims to evaluate and compare the effectiveness of different palatal dressing materials on wound healing following free gingival graft harvesting.
- Conditions
- Palatal Wound Healing, Mucogingival Defects, Free Gingival Graft Donor Site
- Trial name
- OXYHA-FGG (NCT07683351)
- Testing
- Hyaluronic Acid gel, Active oxygen gel, Gelatin sponge with flowable composite
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Suez Canal University
Gingival Recession
PRF for Accelerating Palatal Healing
Backgroung: Various agents are used to reduce post-operative complications associated with palatal donor site surgery for free gingival graft (FGG) harvesting.
- Trial name
- NCT02712242
- Testing
- Platelet Rich Fibrin, Butyl cyanoacrylate, Wet gauze
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Wound Heal
Effects of StellaLife Oral Care Recovery Kit on Palatal Wound Healing After Free Gingival Graft
This study looks to compare the clinical effects of StellaLife VEGA Oral Care Kit with chlorhexidine mouth-rinse on patient comfort, wound healing, wound epithelialization, bacterial levels, and colonization of the wounds.
- Trial name
- NCT05921513
- Testing
- Free Gingival Graft Procedure
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Gingival Recessions, Gingival Recession, Mucogingival Surgery
Histological and Clinical Evaluation of De-epithelialized Connective Tissue Grafts Obtained by Different Methods
This randomized controlled clinical study aimed to evaluate the effectiveness of two different de-epithelialization techniques-extraoral scalpel and intraoral radiofrequency (RF)-used in the preparation of de-epithelialized…
- Trial name
- DEEP-RCT (NCT07521566)
- Testing
- Extraoral de-epithelialization Group, Radiofrequency De-epithelialization
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Lack of Keratinized Gingiva, Mucogingival Deformity - Insufficient Keratinized Tissue
Star Matrix vs Autogenous Graft for Gingival Augmentation: Split-Mouth RCT
This split-mouth randomized controlled clinical trial will test whether a ready-to-use collagen membrane (Star Matrix) can widen the protective band of gum tissue (keratinized gingiva) as effectively as the standard free gingival…
- Trial name
- NCT07440303
- Testing
- Starmatrix collagen membrane, Autogenous gingival graft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Postoperative Pain
Factors Influencing Postoperative Pain After Gingival Graft Harvesting
This prospective cohort study aims to evaluate patient-related, psychological, and clinical factors influencing postoperative pain following gingival graft harvesting from the palate.
- Trial name
- NCT07377370
- Testing
- Gingival graft harvesting from the palate
- Where
- Spain
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Pain, Postoperative, Gingival Diseases
Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery
When harvesting autogenous free grafts to treat periodontal conditions (e.g., lack of attached keratinized tissue, ridge defects, and other mucogingival deformities), the hard palate is the preferred donor site.
- Trial name
- NCT04957342
- Testing
- amnion-chorion membrane, Sutures
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Free Gingival Graft, Survey and Questionnaire
Free Gingival Graft Patients' Treatment Perception and Experience
Free gingival graft (FGG) is a common and effective periodontal procedure used to improve gum health; however, it can involve challenges such as postoperative pain and discomfort due to the requirement of a secondary donor site.
- Conditions
- Free Gingival Graft, Survey and Questionnaire, Postoperative Pain
- Trial name
- NCT07568327
- Testing
- Free Gingival Graft
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Single Recession Defects (RT2)
Clinical Evaluation Comparing Tunneled Coronally Advanced Flap and Modified Coronally Advanced Tunnel With Connective Tissue Graft for Managing Single Gum Recession
The technique under investigation aims to provide effective root coverage while offering the advantage of being less invasive.
- Trial name
- NCT07239180
- Testing
- Modified Coronally Advanced Tunnel with Connective Tissue Graft, Tunneled Coronally Advance Flap with Connective Tissue Graft
- Volunteers
- 24 people
- Sponsor
- Cairo University
Gingival Recession
Tunnel vs. CAF for the Treatment of Multiple Gingival Recessions
Many studies have compared the tunnel technique and coronally advanced flap in the treatment of single and multiple recessions. However, there is a lack of evidence that compared both techniques in combination with a connective…
- Trial name
- NCT05122468
- Testing
- Connective tissue Harvest and CAF, Connective tissue Harvest and Tunnel
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Gingival Recession
Evaluation of Esthetic Root Coverage Using Platelet-Rich Fibrin Versus Subepithelial Connective Tissue Graft With Vestibular Incision Subperiosteal Tunnel Access in Multiple Gingival Recessions
Patients with gingival recession, complain of excessive tooth length that affects their appearance during smiling or functioning.
- Trial name
- NCT03588052
- Testing
- VISTA using PRF, VISTA using SCTG
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lack of Keratinized Gingiva
Titanium Tacked Soft Tissue Stabilization : A Novel Technique For Free Gingival Graft Fixation
A case series study on ten patients with lack of keratinization in the non-esthetic area .the purpose of the study is the evaluation of using the titanium tacks in free gingival graft fixation as an alternative to the…
- Trial name
- NCT05287152
- Testing
- titanium tacks or pins
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Egyptian Biomedical Research Network
Gingival Recession, Localized
Effectiveness of Modified-free Gingival Graft for Treatment of Localized Gingival Recession Defects
The aim of the present study is to evaluate, whether use of the modified free gingival graft (mod-FGG) technique improves treatment outcomes after surgical root coverage at mandibular incisors with gingival recession defects.
- Trial name
- NCT04718545
- Testing
- Mucogingival surgery
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Edentulous Alveolar Ridge In Mandible
Clinical Effects of Keratinized Mucosa Augmentation Around Dental Implant With Free Gingival Graft in Different Surgical Timing at Mandibular Posterior Sites
This study aims to compare clinical outcomes and tissue stability at implant sites in the mandibular posterior region with insufficient buccal keratinized gingiva.
- Trial name
- NCT07088172
- Testing
- free gingival grafts during the second stage of implant surgery, free gingival grafts prior to the implantaion
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine