Clinical trials: Goals, open to volunteers
Palliative Care, Generative Artificial Intelligence
Patient Aid for Theory-Driven Health Communication (PATH): Translating Goal-Power Theory Into an Instrument and Generative AI Support for Palliative Care Communication
The goal of this clinical trial is to learn whether an artificial intelligence (AI)-supported communication tool can help improve communication between people receiving palliative care and their healthcare providers.
- Conditions
- Palliative Care, Generative Artificial Intelligence, Natural Language Processing (NLP)
- Trial name
- NCT07692711
- Testing
- NurseChat+
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Care Delivery, Geriatrics
Understanding the Preferences and Views of Older Adults on the Use of Geriatric and Objective Functional Assessments for Cancer Treatment Planning.
This Interventional clinical study aims to explore how receiving information about their health and physical abilities affects the treatment decisions of older adults.
- Conditions
- Care Delivery, Geriatrics, Geriatric Assessment
- Trial name
- NCT06652347
- Testing
- Cancer care delivery
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Fox Chase Cancer Center
Erectile Dysfunction (ED)
Evaluation of the Rigicon Infla10® Inflatable Penile Prosthesis (IPP) for Erectile Dysfunction
This study evaluates the long-term safety and effectiveness of the Rigicon Infla10® Inflatable Penile Prosthesis in patients with erectile dysfunction.
- Trial name
- UNITED (NCT07273773)
- Testing
- Rigicon Infla10® Inflatable Penile Prosthesis (IPP)
- Where
- 4 sites in United States
- Volunteers
- 182 people
- Sponsor
- Rigicon, Inc.
Musculoskeletal System Disease
Clinical and Biomolecular Assessment for the Monitoring of Patients Undergoing Regenerative Medicine Treatments with Orthobiologics
the aim is to improve the evaluation of the outcomes of regenerative medicine treatments performed in the regenerative medicine centers involved in the study.
- Trial name
- NCT04711551
- Testing
- PRP and related devices to abtain platelet concentrate from whole blood, medullary and adipose tissue and related devices
- Where
- 2 sites in Italy
- Volunteers
- 2,000 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Hypertension, Mobile Application
Development of a Mobile Application Called TansiyoRitim for Hypertension Patients
Based on King's Theory of Goal Success, this project is designed to develop a mobile application called TansiyoRitim for individuals over the age of 18 diagnosed with hypertension.
- Conditions
- Hypertension, Mobile Application, Blood Pressure Control, Treatment Adherence
- Trial name
- NCT07556419
- Testing
- Mobile application, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Kafkas University
Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation
Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI
Provision of interventions that address cognitive and emotional problems faced by Veterans with history of TBI pursuing community reintegration is an important concern for VA.
- Conditions
- Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation, Veteran
- Trial name
- GOALS TH (NCT07190365)
- Testing
- GOALS TH, EDU TH
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Breast Cancer, Lymphedema
Who and Why do Patients Report Lymphedema After Breast Cancer Treatment Without an Objective Measurable Swelling
Breast cancer related lymphedema (BCRL) at the arm and/or trunk is an extremely dreaded complication after breast cancer treatment due to its chronicity and impact.
- Conditions
- Breast Cancer, Lymphedema, Sensory Processing Disorder
- Trial name
- LymphSens (NCT06324721)
- Testing
- Measurements for breast cancer related lymphedema (volumetric measurements, bioimpedance spectroscopy, bioimpedance analysis, tissue dielectric constant measurements, ultrasonography), Measurements for lymphatic problems (volumetric measurements, tissue dielectric measurement, lymphofluoroscopy), Measurements for sensory processing problems by monofilaments, algometer, goniometer, and neurosensory analyzer
- Where
- Belgium
- Volunteers
- 230 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Malignant Melanoma
Follow-up of a National Cohort of Melanoma Resectable Stage II, Stage III or IV Patients or Unresectable Primary
Prevention of melanoma can be efficient but mortality remains unchanged and 15 to 20% of patients still die from melanoma. Indeed metastatic melanoma is a heterogeneous highly and multiple mutations driven cancer.
- Trial name
- MelBase (NCT02828202)
- Testing
- Biological, Tissular, Quality of life
- Where
- 27 sites in France
- Volunteers
- 6,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Doula Support, Postpartum
The Goal is to Examine the Impact of Doula-delivered, Nurse-coordinated Postpartum Care Among Individuals With Preterm Births <34 Weeks' Gestation Requiring NICU Admission.
The primary objective of this research is to conduct a randomized clinical trial to examine the impact of nurse-coordinated, doula-delivered postpartum support (intervention arm) on postpartum health care utilization, health…
- Conditions
- Doula Support, Postpartum, Postpartum Depression (PPD), Postpartum Anemia
- Trial name
- NEST (NCT07787845)
- Testing
- Doula-delivered, Nurse-coordinated postpartum support
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of South Carolina
Lung Ultrasound, Goal Directed Therapy
Lung Ultrasound-guided Hemodynamic Optimization
The formalized expert recommendation of the French Society of Anesthesia and Intensive Care recommends guiding vascular filling by measuring the stroke volume (SV) in surgical patients considered at high risk.
- Conditions
- Lung Ultrasound, Goal Directed Therapy, Non-cardiac Surgery
- Trial name
- POINTBAR (NCT05481723)
- Testing
- noradrenaline and vascular filling, pulmonary ultrasound after vascular filling
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Surgery, Perioperative Complication
BRAIN-targeted Goal-directed Therapy in High-risk Patients undeRgOing Major electIve SurgEry: the BRAIN-PROMISE Study
The aim of the study is to further understand whether the use of non-invasive monitoring NIRS (Near Infrared Spectroscopy) is useful in reducing postoperative complications in high-risk patients undergoing elective surgery.
- Trial name
- BRAINPROMISE (NCT04266574)
- Testing
- Near Infrared Spectroscopy (NIRS), Standard Care
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Clinico Humanitas
Parkinson Disease, Healthy Adult
A Novel Accessible and Widespread Healthcare Service Model Based on Technology Innovation for Objective (Early) Diagnosis and Therapeutic Monitoring of Parkinson's Disease Promoting Continuity of Care
The present study aims to use the SensMode System - a system composed of wearable devices for upper and lower limb movement analysis and electronic device for data acquisition and processing - on healthy subjects, subjects with…
- Trial name
- OLIMPIA (NCT06907589)
- Testing
- Motor Data Analysis
- Where
- 5 sites in Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Esophagus Cancer
Goal-directed Enteral Nutritional Perioperative Management
This clinical trial aims to determine whether perioperative goal-directed nutritional therapy can prevent postoperative pulmonary and other major complications in malnourished esophageal squamous cell cancer patients.
- Trial name
- GENTLEMAN (NCT06510543)
- Testing
- Goal-directed EN therapy, Conventional EN therapy
- Where
- 17 sites in China
- Volunteers
- 400 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Hypertension, Diabetes Mellitus
Goal Commitment and Proactive Health Behavior in Chronic Disease Patients
Chronic diseases such as hypertension, diabetes, and dyslipidemia are major contributors to mortality and healthcare burden worldwide.
- Conditions
- Hypertension, Diabetes Mellitus, Dyslipidemia
- Trial name
- NCT07552571
- Testing
- Goal Commitment-Based Behavioral Intervention, Usual Care
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Xiong Juyang
Quality of Life, Objective Masticatory Performance
Prosthetic Rehabilitation and Its Influence on Masticatory Performance and QoL in Patients Treated for HNC
The main goal of this clinical trial (pilot study) is to evaluate whether prosthetic rehabilitation modifies objective masticatory performance, subjective masticatory performance, quality of life, salivary flow and pH in patients…
- Conditions
- Quality of Life, Objective Masticatory Performance, Subjective Masticatory Performance, Oral Health
- Trial name
- NCT06124222
- Testing
- Prosthetic oral rehabilitation
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- University of Barcelona
Erectile Dysfunction
The Objective of This Phase 1 Study is to Evaluate the Food Effect of 100 mg Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fed Versus 100 mg of Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fasted Conditions in Healthy Adult Male Subjects
The objective of this phase 1 study is to evaluate the food effect of 100 mg Hezkue Turbo® (ASP-001.1, sildenafil) under fed versus 100 mg of Hezkue Turbo® (ASP-001.1, sildenafil) under fasted conditions in healthy adult male…
- Trial name
- NCT06872866
- Testing
- ASP-001.1
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aspargo Labs, Inc
Parkinson's Disease, Parkinson
Comparing Biomarker-Guided DBS Programming With Standard Clinical Monopolar Programming
The goal of this clinical trial is to learn whether an objective, data-guided approach to programming deep brain stimulation (DBS) can improve motor outcomes in people with Parkinson's disease who undergo DBS surgery.
- Conditions
- Parkinson's Disease, Parkinson, Parkinsons Disease (PD), Motor Fluctuations
- Trial name
- NCT07369310
- Testing
- Conventional DBS Programming (Monopolar Review), Objective-Guided DBS Programming (Imaging and Local Field Potential-Based)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Intracranial Artery Stenosis
Efficacy and Safety of a New Balloon Microcatheter in the Treatment of Intracranial Artery Stenosis
The primary objective of this trial is to evaluate the safety and efficacy of a new balloon microcatheter in patients with intracranial artery stenosis.
- Trial name
- NCT07170618
- Testing
- balloon microcatheter
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Sinomed Neurovita Technology Inc.
Shared Decision-Making, Quality of Life
Empowering Monterey Bay Residents for Activated, Collaborative, and Equitable Care
The purpose of the EMBRACE Study is to evaluate whether a facilitated intervention improves shared decision-making (SDM) and patient activation among low-income and minority individuals more than usual care only.
- Conditions
- Shared Decision-Making, Quality of Life, Advanced Illness, Terminal Illness
- Trial name
- EMBRACE (NCT07652359)
- Testing
- Research Assistant Support
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Stanford University
Obesity & Overweight
Redefining Evaluation of Adiposity and Leanness: Broadening Objective Diagnostics for Obesity
The purpose of this study is to evaluate body composition across a variety of medical, professional, and commercial devices, including: bioelectrical impedance analysis (BIA) devices, 3-dimensional optical imaging (3DO), manual…
- Trial name
- REAL-BODY (NCT07776678)
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Foundation for the National Institutes of Health