Clinical trials: Graft Function
Pulmonary Function, Coronary Artery Disease
Additional Effects of Ujjayi Pranayama
Studying the impact of Ujjayi pranayama on post-Coronary Artery Bypass Grafting (CABG) patients has the potential to positively influence healthcare.
- Trial name
- NCT06663800
- Testing
- Ujjayi Paranayama, Standard Protocol
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Coronary Artery Disease, Mitral Valve Insufficiency
Physical and Functional Recovery From Cardiac Surgery in Hospitalized Patients: A Feasibility Pilot Study
Ambulation following surgery has been found to be beneficial for patients; however, nurses and doctors struggle with getting post-operative, hospitalized patients to walk on their own.
- Conditions
- Coronary Artery Disease, Mitral Valve Insufficiency, Aortic Valve Stenosis, Aortic Valve Regurgitation
- Trial name
- NCT02375282
- Testing
- Ambulation orderly
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Baystate Medical Center
Renal Transplantation
Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation
This study intends to determine whether steroid withdrawal or calcineurin inhibitor withdrawal is superior for graft function and graft survival.
- Trial name
- CISTCERT (NCT00903188)
- Testing
- cyclosporine, Everolimus
- Where
- 5 sites in Belgium
- Volunteers
- 152 people
- Sponsor
- University Hospital, Antwerp
Coronary Artery Disease
Tai Chi Exercises on Physical Activity and Pulmonary Function in CABG
To improve the cardiopulmonary endurance in Coronary artery bypass grafting (CABG) patients. Internationally in cardiac hospital facility of cardiac rehabilitation is available to improve the patient's physical activity and…
- Trial name
- NCT03857282
- Testing
- Aerobic Exercises, Tai Chi Exercises
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Riphah International University
Kidney Transplantation, Renal Transplantation
Attenuating Ischemia Reperfusion Injury After Living Donor Renal Transplantation
Patients undergoing living donor renal transplant will be asked to participate to determine whether pre-operative dosing of immunosuppressive medication, and the donor organ receiving an additional dose of antibody induction…
- Conditions
- Kidney Transplantation, Renal Transplantation, Reperfusion Injury
- Trial name
- NCT01149993
- Testing
- Myfortic (mycophenolic acid), Thymoglobulin (anti-thymocyte globulin)
- Sponsor
- Georgetown University
Liver Diseases
YSPSL for Prevention of Delayed Graft Function in Cadaveric Liver Transplantation
The study is designed to assess the feasibility of evaluating YSPSL for the amelioration of ischemia reperfusion injury following liver transplantation by administering YSPSL into the liver graft directly ex vivo via the portal…
- Trial name
- NCT00450398
- Testing
- YSPSL
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Y's Therapeutics, Inc.
Postoperative Coronary Artery Bypass Grafting (CABG), Chronic Obstructive Pulmonary Disease (COPD)
The Effect of Neuromuscular Electrical Stimulation
The effect of neuromuscular electrical stimulation on muscle atrophy in sedated patients on intensive care was studied. The aim of this study was to explore if electrical stimulation could prevent muscle atrophy.
- Conditions
- Postoperative Coronary Artery Bypass Grafting (CABG), Chronic Obstructive Pulmonary Disease (COPD), Ventilatory Failure
- Trial name
- NCT00442728
- Testing
- ELECTRICAL STIMULATION
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Provinciale Hogeschool Limburg
Coronary Artery Bypass, Cardiac Rehabilitation
Effects of Diaphragm Release Technique on Sleep Quality and Respiratory Function in Coronary Artery Bypass Graft Patients
This study aims to investigate the effects of diaphragm relaxation technique on sleep quality and respiratory functions in patients who have undergone coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT07470034
- Testing
- Intervention Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sanko University
Waning Donor Chimerism, Waning Immune Function
CD34+ Stem Cell Infusion to Augment Graft Function
The purpose of this study is to determine if infusing additional special donor cells will help to improve graft or immune function in previously transplanted children with immune deficiencies and bone marrow failures.
- Conditions
- Waning Donor Chimerism, Waning Immune Function, Primary Immunodeficiency Disease(s), Bone Marrow Failure
- Trial name
- NCT01856582
- Testing
- CD34+
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Coronary Artery Disease, Coronary Artery Disease (CAD)
Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL)
This randomized multicenter trial compares coronary artery bypass grafting (CABG) with percutaneous coronary intervention (PCI) in 358 patients with ischemic left ventricular dysfunction and multivessel coronary disease.
- Conditions
- Coronary Artery Disease, Coronary Artery Disease (CAD), Multivessel Coronary Artery Disease, CABG
- Trial name
- STICH 3*0-NL (NCT07269366)
- Testing
- CABG, PCI
- Where
- Netherlands
- Volunteers
- 358 people
- Sponsor
- University Medical Center Groningen
Delayed Graft Function, Kidney Transplantation
Eculizumab for Prevention of Delayed Graft Function (DGF) in Kidney Transplantation
The purpose of this study is to evaluate the efficacy of Eculizumab in the prevention of Delayed Graft Function following deceased donor kidney transplantation.
- Conditions
- Delayed Graft Function, Kidney Transplantation, Complement Activity
- Trial name
- NCT01919346
- Testing
- Eculizumab, Normal Saline
- Where
- 5 sites in United States
- Volunteers
- 21 people
- Sponsor
- Heeger, Peter, M.D.
Brain Death, Kidney Transplantation
Cyclosporine A Pretreatment and Kidney Graft Function
Organ donors included in the study are randomized to a control group or an intervention group receiving 2.5 mg/kg of cyclosporine A before organ procurement.
- Trial name
- Cis-A-Rein (NCT02907554)
- Testing
- cyclosporine A
- Where
- France
- Volunteers
- 648 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cardiovascular Diseases
Effects of Lower Limb Resistance Band Exercises in Phase 1 Cardiac Rehabilitation
This study will be randomized controlled trial with non-probability purposive sampling. Study conducted among post CABG patients. Sample size will be 56, 28 in each group.
- Trial name
- NCT06319651
- Testing
- Lower Limb Resistance Band Exercises, Routine Phase 1 cardiac rehabilitation
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University
Stroke
Home-Based Automated Therapy of Arm Function After Stroke Via Tele-Rehabilitation
Constraint-Induced Movement therapy, also known as CI therapy, is an approach to physical rehabilitation derived from basic behavioral and neuroscience research.
- Trial name
- NCT01157195
- Testing
- Tele-AutoCITE, CI therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Kidney Function, Kidney Transplant; Complications
Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation
Furosemide is an old drug that has been used frequently in the postoperative period of kidney transplantation, aiming to achieve adequate urine output.
- Conditions
- Kidney Function, Kidney Transplant; Complications, Delayed Graft Function
- Trial name
- FOSTIK (NCT03071536)
- Testing
- Furosemide Injection
- Where
- Thailand
- Volunteers
- 360 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Breast Cancer
Acupuncture Chemotherapy-Induced Peripheral Neuropathy (CIPN) IRG
The goal of this clinical research study is to compare the level of effectiveness for 2 acupuncture treatment schedules for chronic CIPN in breast cancer survivors.
- Trial name
- NCT01815346
- Testing
- Acupuncture, Questionnaires, Hand Function and Balance Tests
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
Atrium; Fibrillation
Echocardiographic Left Atrial Function Assessment and Atrial Fibrillation Post-Coronary Artery Bypass Surgery
The aim of this study to investigate the correlation between preoperative LA function using 2D echocardiography and left atrium 2D speckle tracking strain echocardiography and the development of Post Operative AF after CABG.
- Trial name
- NCT03487419
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Heart Institute, Egypt
Ischemia Reperfusion Injury, Delayed Graft Function
Safety and Efficacy of Treprostinil (Remodulin®) In Reducing Ischemia-Reperfusion Injury During Kidney Transplantation
The objectives of this study are to test the preliminary safety and efficacy of a two-day peri-operative course of treprostinil in reducing ischemia-reperfusion injury in adult patients receiving a deceased donor kidney…
- Trial name
- NCT04005469
- Testing
- Treprostinil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rhode Island Hospital
Delayed Function of Renal Transplant
Effects of the Use of "de Novo" Everolimus in Renal Tranplant Population
This is an open, randomized, single-center study. The selected patients will be first divided into two major groups according to the type of organ to be transplanted: standard criteria donor (SCD) or extended criteria (ECD)…
- Trial name
- NCT01663805
- Testing
- Everolimus
- Where
- 3 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- MARIO ABBUD FILHO
Function of Renal Transplant
Analysis of Foxp3 and Vimentin Expression in Renal Transplant Recipient
This observational study is designed to analyse the urinary mRNA expression of Foxp3 and Vimentin, two genes involved in tolerance and early graft dysfunction in 500 renal transplant recipients from 17 renal transplant site in…
- Trial name
- TUFEV (NCT01443013)
- Testing
- Renal Transplant
- Where
- France
- Volunteers
- 266 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris