Clinical trials: HEART ARREST
Out-Of-Hospital Cardiac Arrest, Mobile Phone Use
Impact of Mobile Phone Application Use on Adult BLS
The aim of the study is to investigate whether a serious smartphone game (called MOBI-CPR game) used in the home environment has an impact on the retention of adult basic life support knowledge and skills.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Mobile Phone Use, Stress, Knowledge, Attitudes, Practice
- Trial name
- MOBI-CPR (NCT05784675)
- Testing
- MOBI-CPR game
- Where
- Slovenia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nino Fijačko
Physician Judgment
Understanding Physician Signout Risk Perception
The purpose of the study is to compare the ability of physicians and a statistical index (the Rothman score) to predict clinical deterioration over the next 24 hours.
- Trial name
- UPS (NCT02648828)
- Testing
- Clinical deterioration
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cardiac Arrest, Inflammation
Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
This is a prospective, observational study to investigate molecular mechanisms mediating the systemic inflammatory process, and changes to metabolism, and their impact on brain injury, survival, and functional outcomes after…
- Conditions
- Cardiac Arrest, Inflammation, Obesity, Hypoxic Ischemic Encephalopathy (HIE)
- Trial name
- PCAS (NCT02664831)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- MaineHealth
Sepsis, Septic Shock
The Role of Serotonin in Intensive Care Patients
Sepsis, cardiac arrest and multiple trauma are potentially life-threatening conditions and common reasons for intensive care unit (ICU) admission.
- Conditions
- Sepsis, Septic Shock, Cardiac Arrest With Successful Resuscitation, Multiple Trauma
- Trial name
- SERO-22 (NCT05386199)
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest
Technological and Patient-tailored Innovations for Maximizing Effectiveness of Cardiac Arrest Resuscitation
Out-of-hospital cardiac arrest (OHCA) affects 275,000 people in Europe every year. In Italy alone, 50,000 people experience OHCA annually, with only 9% surviving. Half of the survivors suffer severe brain damage.
- Trial name
- TIME-CARE (NCT06538155)
- Testing
- Wearable device, Cardiopulmonary resuscitation, CT scan, TEE exam, or chest X ray
- Where
- 3 sites in Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Cardiac Arrest
Ultra-Brief Versus Brief Hands Only CPR Video Training With and Without Psychomotor Skill Practice
Bystander CPR improves survival from Out of Hospital Cardiac Arrest. This study examines the efficacy of ultra-brief video training for Hands-Only CPR.
- Trial name
- NCT01191736
- Testing
- No training, assessed within 60 mins, Ultra-brief video; assessed in 60 mins, Brief video; assessed in 60 mins
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Valleywise Health
Cardiac Arrest
Intubation During Adult Intubation
The objective of this study is to compared effectiveness of intubation using ETView VivaSight SL and standard tracheal tube during resuscitation performed by a EMS-paramedics.
- Trial name
- SLETI (NCT02305524)
- Testing
- ETView VivaSight SL, Macintosh laryngoscope
- Where
- Poland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Injury
Better First Aid With First Aid Training and Dispatcher Central Instructions?
The study evaluates the effect of a first aid course on first aid skills compared to no training. The study also evaluates the effect of first-aid instructions given by emergency dispatch central over mobile phone on first aid…
- Trial name
- NCT02391922
- Testing
- First aid course, First aid instructions by mobile phone
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Tromso
Pediatric Cardiac Arrest (Simulated)
Examining the Effect of a Scripted Debriefing on Resuscitation Performance in Pediatrics
The investigative team's purpose for conducting this research is to improve effective and efficient translation and implementation of evidence based advanced life support practice to providers of care for children.
- Trial name
- EXPRESS (NCT01682629)
- Testing
- Debriefing Script, High Physical Realism Simulation
- Where
- Canada
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Sepsis, Septic Shock
Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Background: Central Venous catheter insertion technique and indwelling time are major risk factors for CVC colonisation. Colonisation occurs through microbial migration and biofilm formation along the catheter insertion tract.
- Conditions
- Sepsis, Septic Shock, Post-cardiac Surgery, Post-Cardiorespiratory Arrest Coma
- Trial name
- NCT03270774
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makerere University
Cardiac Arrest
Prospective Study of 3 Phone Assistance Strategies to Achieve a Continuous Cardiac Massage
This study must evaluate the benefit of a continuous audio guidance on the effectiveness of MCE directed by a volunteer. The evaluation of the MCE for this study is based on both quantitative criteria (based on the…
- Trial name
- TeleMacc (NCT01936597)
- Testing
- Therapeutic and preventive strategies
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Teaching CPR
Efficacy of CPR Teaching in Mass Training
This prospective study evaluate teaching efficacy of CPR training using different methods in general population, medical students and non medical students with the 12 months evaluation of its recall
- Trial name
- NCT02120573
- Testing
- Workshop using Lecture and human model, Workshop using Educational Film, Workshop using Lecture, human model as well as Educational Film
- Where
- Iran
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Sudden Cardiac Arrest
Research on Attitudes, Confidence, and Practical Skills in Performing Cardiopulmonary Resuscitation and Automated External Defibrillation After Completing a Course Based on the European Resuscitation Council Model
Research on attitudes, confidence, and practical skills in performing cardiopulmonary resuscitation and automated external defibrillation after completing a course based on the European Resuscitation Council model
- Trial name
- RACE-CPR (NCT07331831)
- Where
- Bulgaria
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- First Three Minutes Foundation
Brain Death, Anoxic Brain Injury
Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination
Current standard of care prior to determination of brain death in subjects with suspected anoxic brain injury is to exclude complicating medical conditions that may confound clinical assessment (such as severe electrolyte, acid…
- Conditions
- Brain Death, Anoxic Brain Injury, Cardiac Arrest, Sedative Intoxication
- Trial name
- NCT03743805
- Testing
- Flumazenil, Naloxone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Prisma Health-Midlands
Infertility, Male, Infertility Unexplained
Using of Testes Shocker in Improving the Spermatogenesis and Sperms Activity
Infertility was reported in approximately 15% of all heterozygous couples, with male factor accounting for nearly half the cases.
- Conditions
- Infertility, Male, Infertility Unexplained, Infertility Due to Complete Spermatogenic Arrest, Oligospermia
- Trial name
- NCT05506722
- Testing
- Testes shocker
- Where
- Iraq
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Cardiopulmonary Resuscitation, Cardiac Arrest
Physical Workload Identify in Chest Compression Position Using Surface Electromyogram
The chest compression depth decreases over time after starting continuous chest compression due to the rescuers' fatigue. The investigators hypothesized that the frequency parameters from surface electromyogram from each muscle…
- Trial name
- NCT02088879
- Testing
- chest compression with kneeling position, chest compression with standing position
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Dental Caries
LT Comparative Effectiveness of 2 Caries Treatments
This study is a continuation of a cluster randomized clinical trial (cRCT) conducted in 33 publicly subsidized housing facilities/sites (HUD Section 202) and other low-income housing voucher programs in NE Ohio.
- Trial name
- NCT07213661
- Testing
- A "simple medical strategy" consisting of silver diamine fluoride (SDF), A "typical dental strategy" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride Varnish (FV)
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Cardiac Arrest (CA)
Feasibility of Appropriate Smartphone Position During Video-assisted Cardiopulmonary Resuscitation
There is a gap in our knowledge regarding whether video-assisted cardiopulmonary resuscitation (V-CPR) is feasible when a lay responder is alone at the scene.
- Trial name
- NCT06794398
- Testing
- V-CPR inside a room when the lay responder is alone (no operator for holding the phone), V-CPR in a yard (outside environment) when the lay responder is alone (no operator for holding the phone)
- Where
- Hungary
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Out-Of-Hospital Cardiac Arrest
iGOGO -Assessment of CPR Skill,Willingness and Public AED in Layperson:A Cohort Study
Out-of-hospital cardiac arrest (OHCA) is an important public health issue. Chang Gung Memorial Hospital, a university affiliated medical center in Taoyuan city, northern Taiwan, actively cooperated with government policy with 250…
- Trial name
- NCT05659108
- Testing
- CPR
- Where
- Taiwan
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Sepsis, Cardiac Arrest
Validation of Molecular and Protein Biomarkers in Sepsis
Background: Sepsis (blood poisoning) is a clinical syndrome characterised by a dysregulated host response to infection causing life-threatening organ dysfunction which results in admission to an intensive care unit.
- Conditions
- Sepsis, Cardiac Arrest, Pneumonia, Abdominal Sepsis
- Trial name
- VAMp-sepsis (NCT04289506)
- Testing
- mRNA expression
- Where
- 3 sites in United Kingdom
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Public Health England