Clinical trials: HIV Primary Infection
HIV Infection Primary, Hepatitis, Viral, Human
Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis
Pre-exposure prophylaxis (PrEP) based on tenofovir represents a considerably new preventive intervention that has shown to significantly decrease the number of HIV infections while it enables early diagnosis of HIV and other…
- Conditions
- HIV Infection Primary, Hepatitis, Viral, Human, Sexually Transmitted Infections, Excluding HIV and Hepatitis
- Trial name
- SeVIHPrEP (NCT05492565)
- Testing
- Tenofovir Disoproxil Fumarate 300 MG Oral Tablet
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
HIV/AIDS and Infections, Drug Abuse
Preventing HIV/STI in Urban Adolescents Via an mHealth Primary Care Intervention
The study evaluates the preliminary efficacy of an innovative mobile-health (mHealth) intervention (hereon referred to as S4E) to improve human immunodeficiency virus and sexually transmitted infection testing and reduce HIV/STI…
- Conditions
- HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage
- Trial name
- NCT03368456
- Testing
- S4E, Usual Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Michigan
HIV Infections, Sexually Transmitted Infections
HIV Prevention Program for African American Teen Males
The purpose of this study is to test if sexual health interventions can reduce the incidence of STIs among African American teens (15 to 21 years old).
- Trial name
- NCT00849823
- Testing
- Male Sexual Health Program, Focus on the Future Program
- Where
- United States
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
Human Immunodeficiency Virus, Acquired Immunodeficiency Syndrome
Self-Test Strategies and Linkage Incentives to Improve ART and PrEP Uptake in Men
This is a randomized controlled trial to test a combination behavioral and biomedical interventions to improve the HIV prevention and care cascades in a population of mobile men in a high priority setting (fishermen in Kenya).
- Conditions
- Human Immunodeficiency Virus, Acquired Immunodeficiency Syndrome, HIV Infections, Sexually Transmitted Diseases, Viral
- Trial name
- NCT04772469
- Testing
- Provision of multiple self-tests, Small monetary incentives, Use of SMS/text reminders to motivate adherence to ART or PrEP
- Where
- Kenya
- Volunteers
- 934 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
HIV I Infection
Leveraging Family-Based Assets for Black MSM In House Ball Communities
Despite the advent of highly effective prevention tools such as HIV pre-exposure prophylaxis (PrEP), Black men who have sex with men (MSM) continue to have the highest incidence of new HIV diagnoses in the US but are least likely…
- Trial name
- NCT05071378
- Testing
- Our Family, Our Voices
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- State University of New York - Downstate Medical Center
HIV Infection Primary
Assessing Differential Adherence to Medications and Quality of Life Among People Living With HIV and Comorbidities
The investigators propose to utilize quantitative and qualitative methodology to better understand the impact of multiple drug use (polypharmacy) on medication adherence as well as the driving forces behind differential adherence…
- Trial name
- TEAMH (NCT03387397)
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Hiv
Engaging Men Through HIV Self-Testing With Differentiated Care to Improve ART Initiation and Viral Suppression Among Men in Malawi
Men in sub-Saharan Africa who test HIV-positive continue to have poor ART initiation and retention outcomes. The proposed project will test a home-based ART intervention for men who are living with HIV compared to facility-based…
- Trial name
- NCT04858243
- Testing
- Home-Based ART, Facility-Based ART
- Where
- Malawi
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV Infections, Men
Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging
This study will evaluate the impact of U=U messaging and counseling on gaps in the HIV care cascade for men, including testing uptake and ART initiation (Aim 1), achieving viral suppression and retention in care (Aim 2) in two…
- Conditions
- HIV Infections, Men, Treatment Adherence
- Trial name
- NCT05602376
- Testing
- U=U testing messaging scripts, U=U adherence messaging scripts
- Where
- 2 sites in South Africa
- Volunteers
- 3,642 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Mental Health Issue, Hiv
Walk-in Therapy in Low Barrier Primary Care
The goals of the current research are to adapt an effective walk-in psychotherapy clinic intervention for the context of low-barrier primary care; and conduct a pilot implementation study in a low-barrier primary care clinic…
- Conditions
- Mental Health Issue, Hiv, Substance Use
- Trial name
- NCT06552325
- Testing
- Single Session Narrative Therapy
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Washington
Diabetes, Chronic Kidney Diseases
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)
This research programme seeks to combine the resources of NHS primary care, with the leading spectroscopic work in low-magnetic fields of the Wilson Group (Nottingham Trent University) to demonstrate the potential for benchtop…
- Conditions
- Diabetes, Chronic Kidney Diseases, Cancer, Bowel Disease
- Trial name
- BRANCH-P (NCT05473325)
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Willows Health
Sexually Transmitted Diseases, HIV
Effectiveness of HIV Risk Reduction Program Among African American Men
This study will test the effectiveness of a brief clinic-based program designed to promote the correct use of condoms among young African-American men newly diagnosed with a sexually transmitted disease.
- Trial name
- NCT00314028
- Testing
- Focus on the Future, Control standard of care treatment
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
Quality of Health Care, HIV/AIDS
Using Electronic Medical Record Data to Improve HIV Primary Care
This cluster randomized control trial examines whether an audit and feedback study improves care of patients living with HIV/AIDS in a family health team setting.
- Conditions
- Quality of Health Care, HIV/AIDS, Electronic Health Records
- Trial name
- NCT04107233
- Testing
- Audit and Feedback
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HIV Infections, Cancer, Second Primary
Micronutrient Supplemented Probiotic Yogurt for HIV/AIDS and Other Immunodeficiencies
We hypothesize that micronutrient fortified probiotic yogurt can improve nutritional status and enhance immunity parameters in subjects HIV/AIDS and other immunodeficiencies.
- Trial name
- NCT00517803
- Testing
- Probiotic Yogurt B: with various micronutrients, Probiotic Yogurt A: Kaiser micronutrients, Probiotic yogurt C: with basic micronutrients
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
HIV Infections
Impact of a Telenovela/Soap Opera for HIV Prevention in Latinas
Latinas continue to be affected disproportionally by HIV in the United States (US). Often, Latinas are not aware of their HIV status.
- Trial name
- NCT05929482
- Testing
- Infección de Amor (Infectious Love)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV-1-Associated Cognitive Motor Complex
The Prevalence of Neurocognitive Disorder in a Primary Care-based HIV Cohort Compared to a HIV-negative Control Cohort -
To determine the prevalence of HIV associated Neurological Disorder (HAND) in a population of HIV positive patients within a primary care setting compared with the HIV negative population.
- Trial name
- CNS HAND (NCT01434563)
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Holdsworth House Medical Practice
Pre-Exposure Prophylaxis, Hiv
Peer-led Social Media Intervention to Prevent HIV Among Young Men Who Have Sex With Men (YMSM)
The aim of this study is to examine the effect of social media intervention on the use of pre-exposure prophylaxis (PrEP) by young men who have sex with men (YMSM) in the greater New Haven area.
- Conditions
- Pre-Exposure Prophylaxis, Hiv, Men
- Trial name
- NCT04417946
- Testing
- PrEP messages, Heath messages
- Where
- 2 sites in United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Yale University
Hiv, Chlamydia
Online HIV Prevention for Young Male Couples
Young gay, bisexual, and other men who have sex with men (YMSM) are the only risk group in which rates of new HIV infections are on the rise.
- Conditions
- Hiv, Chlamydia, Gonorrhea
- Trial name
- 2GETHER (NCT03284541)
- Testing
- 2GETHER, Existing Public Health Practice
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Northwestern University
HIV Infections
Workplace-based HIV Self-testing Among Men in Uganda (WISe-Men)
This study seeks to determine whether workplace delivery of HIV self-testing will lead to an increase in uptake of HIV testing and subsequent linkage to care or prevention services among men in Uganda.
- Trial name
- NCT04164433
- Testing
- Oral HIV Self-Test (OraQuick)
- Where
- 2 sites in Uganda
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Makerere University
HIV Infections
Motiv82Change: an HIV Prevention Study for Young Latino Men
The purpose of this study is to develop and pilot test a culturally and developmentally tailored Motivational Enhancement Intervention (MEI) to reduce risky sex (unprotected anal sex and multiple partners) among young Hispanic…
- Trial name
- Motiv82Change (NCT00877695)
- Testing
- Entre Culturas: Navigating Culture, Identity, and HIV Risk
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
HIV/AIDS and Infections, Drug Abuse
A Community-University Approach to Preventing HIV
Examine the feasibility and acceptability of delivering the S4E intervention to 20 African-American youths between the ages 16-21 in Flint, Michigan.
- Conditions
- HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage
- Trial name
- NCT03938077
- Testing
- Storytelling 4 Empowerment
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan