Clinical trials: Habituation
Drug Use Disorders, Drug Abuse
Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy Risks
Background: Sixty million American adults suffer from moderate to severe chronic pain. Of these, 5 to 8 million currently use opioids long-term.
- Conditions
- Drug Use Disorders, Drug Abuse, Drug Addiction, Drug Dependence
- Trial name
- CARE (NCT02224508)
- Volunteers
- 1,588 people
- Sponsor
- Kaiser Permanente
Vertigo
Effects of Vestibular Habituation and Ocular Reflex Exercises on Vertigo
The aim of this study is to determine the comparative effects of vestibular Habituation and ocular reflex exercises on Gait stability, Dizziness severity, and fear of fall in elderly population with vertigo
- Trial name
- NCT06760975
- Testing
- Vestibular Habituation Exercises, Ocular Reflex Excercises
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Suicide
Operation Enduring Freedom/Operation Iraqi Freedom Veterans' Experiences of Habituation to Pain, Perceived Burdensomeness, and Failed Belongingness
Veterans possess significant risk factors for self-directed violence (SDV). For example, depressed Veterans are at a greater risk for SDV than the general population.
- Trial name
- NCT01334385
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- VA Eastern Colorado Health Care System
Public Speaking, Social Fear
Exposure With Acceptance-Based Versus Habituation-Based Rationale for Public Speaking Anxiety
The purpose of this study is to compare two exposure-based behavioral group treatments for public speaking anxiety. Specifically, exposure within the context of psychological acceptance will be compared to exposure within a…
- Trial name
- NCT00842946
- Testing
- Exposure w/ Acceptance-Based Rationale, Exposure w/ Habituation-Based Rationale
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Drexel University
Disordered Eating Behaviors, Binge Eating
Enhanced Cue Exposure Therapy for Negative Emotional Eating
The current study aims to evaluate the efficacy of Enhanced Cue Exposure Therapy (E-CET) in reducing negative emotional eating (NEE), compared to an active control intervention, behavioral lifestyle intervention (BLI), in a…
- Trial name
- NCT06012045
- Testing
- Enhanced Cue Exposure Therapy, Behavioral Lifestyle Intervention
- Where
- Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Sleep Control Condition, Insomnia Symptoms Induction Condition
Pain Sensitization and Habituation in a Model of Experimentally-induced Insomnia Symptoms
The main purpose of this study is to learn about the effects of repeated exposure to sleep disruption (3 cycles of sleep disruption, each consisting of three days in a row where sleep is shortened and disrupted, followed by a…
- Trial name
- NCT02484742
- Testing
- Insomnia symptom induction
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Child Development
The Role of Motion in Infants' Ability to Categorize
This study is concerned with psychological and physiological development in infants. Specifically, researchers are interested in when and how babies are able to group similar objects, like animals or vehicles, into the same…
- Trial name
- NCT00362076
- Where
- United States
- Volunteers
- 941 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Mal de Debarquement Syndrome (MdDS)
Treatments of Mal de Debarquement Syndrome (MdDS) by Habituation of Velocity Storage
Mal de Debarquement Syndrome (MdDS) is an under-recognized but nevertheless common balance disorder, which in most cases occurs after exposure to prolonged passive motion.
- Trial name
- NCT04213079
- Testing
- re-adaptation of the vestibulo-ocular reflex, Habituation of velocity storage of the vestibulo-ocular reflex
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Social Anxiety Disorder, Panic Disorder
Optimizing Exposure Therapy for Anxiety Disorders
The study will compare the effects that two different approaches of exposure therapy have on reducing fear and anxiety in individuals with social anxiety disorder or panic disorder.
- Trial name
- OptEx (NCT04048824)
- Testing
- Inhibitory Learning-Based Exposure, Habituation-Based Exposure
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of California, Los Angeles
Post-Traumatic Stress Disorder
Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) With/Without Yohimbine
The proposed study has three distinct but related research objectives. The first goal is to measure physiological correlates of successful treatment with Prolonged Exposure (PE) therapy for posttraumatic stress disorder (PTSD) in…
- Trial name
- NCT01031979
- Testing
- Yohimbine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- VA Office of Research and Development
Addictive Behavior, Food Preferences
Food Choices in Healthy Weight Women
This study will examine differences in habituation to foods high in sugar and fat content versus those that are not, in normal weight women.
- Conditions
- Addictive Behavior, Food Preferences, Food Habits, Healthy
- Trial name
- NCT02481362
- Testing
- CAKE, APRICOTS
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Benign Paroxysmal Positional Vertigo
Habituation Exercises Versus Proprioceptive Training in Benign Paroxysmal Positional Vertigo
The aim of this research is to compare the effects of habituation exercises versus proprioceptive training on vertigo, balance, dizziness and quality of life in the individuals having benign paroxysmal positional vertigo.
- Trial name
- NCT05425199
- Testing
- Habituation exercises + vestibular treatment, proprioceptive training + vestibular therapy, conventional vestibular treatment
- Where
- Pakistan
- Volunteers
- 39 people
- Sponsor
- Riphah International University
Arteriosclerosis, Stress, Psychological
The Effect of Beta-Blockers and Aspirin on Hemostasis and Endothelial Function After Acute Mental Stress
This randomized double-blinded controlled trial uses a factorial design to investigate whether application of beta-blockers (inderal 80 mg) or aspirin (100 mg) or a combination thereof has an effect on the activation of the…
- Trial name
- NCT00174902
- Testing
- inderal (drug), acetylsalicylic acid (drug)
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders
Safety, Tolerability and Abuse Liability Study of Intravenous NRP104 in Adults With Stimulant Abuse Histories
This research is being done to evaluate if NRP 104 is a safe drug. The other purpose is to learn if NRP104, when injected into a vein, produces a high and any other effects like amphetamine and other stimulant drugs that are…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
- Trial name
- NCT00247572
- Testing
- NRP104
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- New River Pharmaceuticals
Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders
Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulant Abuse
This research is being done to evaluate if NRP104 is a safe drug. The other purpose is to learn if NRP104 produces a high and any other effects like amphetamine and other stimulant drugs that are abused.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
- Trial name
- NCT00248092
- Testing
- NRP104
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- New River Pharmaceuticals
Substance Use, Substance Abuse
Family Engagement, Cross-System Linkage to Substance Use Treatment for Juvenile Probationers -- Phase 3
Developed from adapting and combining two evidence-based programs, Project CONNECT (a linkage-to-services program that targets barriers within the probation and substance abuse treatment systems) and TIES (a program that teaches…
- Conditions
- Substance Use, Substance Abuse, Substance Use Disorders, Substance-Related Disorders
- Trial name
- NCT03048552
- Testing
- Family CONNECT
- Volunteers
- 22 people
- Sponsor
- New York State Psychiatric Institute
Autism Spectrum Disorder, Autism
Sensory Habituation in Autism Spectrum Disorders
Autism spectrum disorder (ASD) is one of the most common developmental disabilities and often people with ASD have sensory processing disorders.
- Conditions
- Autism Spectrum Disorder, Autism, Sensory Processing Disorder, Sensory Over-Responsivity
- Trial name
- ASD_VR_RE (NCT06247176)
- Testing
- Sensory Habituation Protocol
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Motion Sickness, Seasickness
Galvanic Vestibular Stimulation as a Novel Treatment for Seasickness
subjects with severe seasickness, who failed to habituate to sea conditions after at least six month of active sailing, were enrolled to the single-blind randomized control study.
- Conditions
- Motion Sickness, Seasickness, Habituation, Vestibular Time Constant
- Trial name
- NCT05004818
- Testing
- GVS stimulation coupled with inverse phase rotatory chair stimulation at sinusoidal harmonic acceleration protocol
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Migraine Disorder, Episodic Migraine
Neurophysiological and Biomolecular Effects of Atogepant in Episodic Migraine
The investigators aim to assess and compare neurophysiological and biochemical changes induced by a 3-month treatment with atogepant (60 mg daily) in patients with high-frequency episodic migraine (8-14 monthly migraine days).
- Trial name
- ATOM (NCT06882122)
- Testing
- Atogepant 60 mg
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Habituation
The Effects of Chewing Gum on a Computer Task and Liking Ratings of Ice Cream
The purpose of this study is to examine if chewing gum before an eating bout will increase the rate of habituation and subsequently reduce energy intake within the eating bout.
- Trial name
- NCT02198911
- Testing
- NO GUM, MCC (Mint Chocolate Chip gum), C (Cinnamon gum)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville