Clinical trials: Hashimoto Thyroiditis
Autoimmune Thyroiditis
Low Level Laser Therapy for Autoimmune Thyroiditis
INTRODUCTION: Chronic autoimmune thyroiditis (TCA) is the main cause of acquired hypothyroidism, which requires continuous treatment with levothyroxine (LT4).
- Trial name
- NCT02240563
- Testing
- Low-level laser therapy, Non laser ordinary red light
- Where
- 2 sites in Brazil
- Volunteers
- 43 people
- Sponsor
- University of Sao Paulo General Hospital
Undefined
Single Ascending-dose Study to Evaluate Safety, Tolerability, and PK of MYMD1 in Healthy Male Adult Subjects
Double-blind, placebo-controlled, First-in-Human, single ascending-dose study. Approximately 40 healthy adult male subjects will be given a single capsule of MYMD1 to determine its safety, how well it is tolerated, how the body…
- Trial name
- NCT04349761
- Testing
- MyMD1
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TNF Pharmaceuticals, Inc.
Hashimoto Thyroiditis
Adjuvant Therapeutic Effect of Vitamin D on Hashimoto's Thyroiditis
The purpose of this study is to explore the relationship between vitamin D and Hashimoto's thyroiditis and to explore whether vitamin D can play an adjuvant role in the treatment of Hashimoto's thyroiditis.
- Trial name
- NCT05871957
- Testing
- Vitamin D Drops
- Volunteers
- 30 people
- Sponsor
- Qianfoshan Hospital
Habitual Abortion
CXCL9 and CXCL11 Levels in Patients With Autoimmune Thyroiditis and Habitual Abortions
The purpose of this study is to measure serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions
- Trial name
- NCT01644318
- Where
- Turkey (Türkiye)
- Sponsor
- Ankara Education and Research Hospital
Hypothyroidism, Subclinical Hypothyroidism
Thyroid Disorders in Malaysia: A Nationwide Multicentre Study
This will be a population based study looking at the prevalence of thyroid disorders in Malaysia (including hypo- and hyperthyroidism, subclinical hypo- or hyperthyroidism) and its association with different ethnicity and iodine…
- Conditions
- Hypothyroidism, Subclinical Hypothyroidism, Hyperthyroidism, Subclinical Hyperthyroidism
- Trial name
- MyEndo-Thyroid (NCT02190214)
- Volunteers
- 2,498 people, healthy volunteers welcome
- Sponsor
- International Islamic University Malaysia
Hashimoto Thyroiditis, Graves Disease
DNA Methylation and Autoimmune Thyroid Diseases
Hashimoto Thyroiditis (HT) and Graves Disease (GD) are known to be caused by abnormal immune response against self cells and tissues.
- Trial name
- THYRODNA (NCT02491567)
- Where
- Greece
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Hashimoto's Disease, Graves' Disease
Autoimmune Thyroid Disease Genetic Study
The hypothesis of this project is that specific genes can be identified that contribute to genetic susceptibility to autoimmune thyroid disease (AITD) in different populations.
- Trial name
- NCT00958113
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- University of Colorado, Denver
Hashimoto Thyroiditis, Mediterranean Diet
The Impact of Change of Thyroid Antibodies on Hormone Level and Disease Burden in Patients With Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT) is an autoimmune disease affecting the thyroid gland and is one of the most common causes of hypothyroidism. Eating habits may affect the risk of several inflammatory and immune diseases, such as HT.
- Trial name
- Anti-TPO/TG (NCT07048821)
- Testing
- Dietary modification
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sherihan AboElyazed Mohamed Khalil
Hashimoto Thyroiditis, Hashimoto Disease
Evaluation of the Effect of Gluten-Free Diet and Mediterranean Diet
Background: Hashimoto's Thyroiditis is an autoimmune disease that attacks thyroid cells through cell- and antibody-mediated immune processes and is characterized by the production of thyroid autoantibodies.
- Trial name
- NCT05949671
- Testing
- mediterranean, gluten-free and mediterranean gluten-free diet intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Acibadem University
Autoimmune Thyroiditis
Gluten-free Diet in Women With Autoimmune Thyroiditis
The purpose of this interventional study was to check if the elimination of gluten from the diet of women with autoimmune thyroiditis affects their health and thyroid function, quality of life, and the gut microbiome composition.
- Trial name
- NCT06249074
- Testing
- Gluten-free diet, Gluten capsules supplementation
- Where
- Poland
- Volunteers
- 31 people
- Sponsor
- Medical University of Gdansk
Graves Ophthalmopathy, Graves Disease
Anti-insulin-like Growth Factor-1 Receptor (IGF-1R) Antibodies in Graves' Disease and Graves' Orbitopathy
The study is aimed at assessing IGF-1R-Abs in patients with Graves' disease, with or without GO, compared with healthy subjects and patients with autoimmune thyroiditis in a cross-sectional investigation.
- Conditions
- Graves Ophthalmopathy, Graves Disease, Autoimmune Thyroiditis
- Trial name
- IGF1RAbsGO (NCT03498417)
- Testing
- Serum antibodies against the IGF-1R
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Hashimoto Disease, Pregnancy Related
Management of Thyroid Function in Hashimoto's Thyroiditis During Pregnancy
The management of thyroid function in pregnancy has been object of several guidelines in the last years. Normal thyroid function reduces prenatal and post-natal risks and gestational complaints.
- Conditions
- Hashimoto Disease, Pregnancy Related, Thyroid Dysfunction
- Trial name
- NCT04613323
- Volunteers
- 100 people
- Sponsor
- Centro Diagnostico Priamar
Autoimmune Diseases, Inflammatory Disease
In Vitro Effect Study of Interleukin-2 Muteins on Regulatory T Cells of Patients With Different Autoimmune, Allo-immune or Inflammatory Diseases
Interleukin 2 (IL-2) is a critical cytokine for the survival and function of regulatory T cells (LTreg). This cytokine has a dual role in the immune system.
- Conditions
- Autoimmune Diseases, Inflammatory Disease, Acquired Bone Marrow Aplasia, Systemic Lupus Erythematosus
- Trial name
- MuTreg (NCT05544448)
- Testing
- Blood sample taken at a single time point
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hashimoto Disease
FGF-21 Levels and RMR in Children and Adolescents With Hashimoto's Thyroiditis (THYROMETABOL)
It is well documented that thyroid hormones (THs) are involved in energy and lipid metabolism, thermogenesis, and body weight control, acting on several tissues.
- Trial name
- THYROMETABOL (NCT02725879)
- Where
- Greece
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Hashimoto
Eye Movement Desensitization and Reprocessing on Autoimmune Thyroiditis in Adults
The purpose of this study is to evaluate whether Eye Movement Desensitization and Reprocessing (EMDR) is effective in decreasing the level of autoantibodies of patients with autoimmune thyroiditis.
- Trial name
- NCT04472988
- Testing
- Eye Movement Desensitization and Reprocessing, Treatment as Usual
- Where
- Romania
- Volunteers
- 91 people
- Sponsor
- University of Bucharest
Thyroid, Obesity
Thyroid in Bariatric Surgery
This study is expected to provide novel data regarding potential structural and functional changes of the thyroid gland in morbidly obese adults following significant weight loss through bariatric surgery.
- Conditions
- Thyroid, Obesity, Insulin Resistance, Autoimmune Thyroiditis
- Trial name
- ThyrBar (NCT03048708)
- Testing
- Bariatric surgery
- Volunteers
- 10 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Hashimoto Thyroiditis, Autoimmune Thyroiditis
Effects of Low-Level Laser Therapy on Oxidative Stress Levels
Hashimoto's thyroiditis (HT) is the most commonly observed inflammatory and autoimmune disease of the thyroid gland. Recent evidence has suggested that low-level laser therapy (LLLT) can improve thyroid function and reduce levels…
- Conditions
- Hashimoto Thyroiditis, Autoimmune Thyroiditis, Thyroiditis, Thyroid Diseases
- Trial name
- NCT04754607
- Testing
- Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul Medipol University Hospital
Hashimoto Thyroiditis
The Effect of Hydroxychloroquine Treatment in Hashimoto's Thyroiditis
Hashimoto's thyroiditis is an autoimmune thyroid disease, which induced chronic inflammation of thyroid gland and destroys thyroid tissue.
- Trial name
- NCT01760421
- Testing
- Hydroxychloroquine
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Autoimmune Thyroiditis
Identity Oriented Psychotrauma Therapy on Hashimoto in Adults
The purpose of this study is to evaluate whether Identity Oriented Psychotrauma Therapy (IOPT) is effective in decreasing the level of autoantibodies of patients with Hashimoto thyroiditis.
- Trial name
- NCT04600349
- Testing
- Identity Oriented Psychotrauma Therapy, Treatment as Usual
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- University of Bucharest
Thyroid Diseases
Preoperative Steroids in Autoimmune Thyroid Disease
This pilot project will randomize a small sample of patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of prednisone alters the inflammation of the gland and…
- Trial name
- NCT04542278
- Testing
- Prednisone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Wisconsin, Madison