Clinical trials: Health-related Quality of Life
Complex Anal Fistula
Success Rate, Continence, and Quality of Life With a Bioprosthetic Plug for Treating Complex Anal Fistula
Anal abscess-fistula disease is of common occurrence and has a significant impact on the quality of life of affected individuals.
- Trial name
- NCT01612195
- Testing
- Anal fistula plug
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- University Hospital, Basel, Switzerland
Non-Small-Cell Lung Carcinoma, Digestive System Neoplasms
Clinical Trial: Effectiveness and Efficiency of Physical Exercise in Cancer Patients
AIM: To evaluate the effectiveness and efficiency of an innovative exercise program (EP) for patients during treatment for gastrointestinal tumors, breast and non small cells lung cancer, in terms of improved quality of life…
- Conditions
- Non-Small-Cell Lung Carcinoma, Digestive System Neoplasms, Breast Neoplasms
- Trial name
- EFICANCER (NCT01786122)
- Testing
- Supervised Physical activity, education program on healthy habits
- Where
- Spain
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Breast Cancer
Lifestyle Intervention for High Risk Cancer Survivors
The goal of this behavioral research study is to find out more about the health behaviors of cancer survivors. Researchers want to understand the cultural, social, and environmental factors related to physical activity and…
- Trial name
- NCT01508273
- Testing
- Exercise Program, Website, Exercise DVD
- Where
- 3 sites in United States
- Volunteers
- 1,150 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Malnutrition, Cancer-related Malnutrition
Nutritional Prehabilitation to Improve Cancer Outcomes (N-PICO)
Brief Summary The goal of this clinical trial is to evaluate the acceptability and adherence of low- and high-intensity remote nutritional interventions for cancer patients in rural and urban areas, specifically focusing on those…
- Conditions
- Malnutrition, Cancer-related Malnutrition, Quality of Life (QOL), Nutritional Support
- Trial name
- N-PICO (NCT07072377)
- Testing
- Intensity of Nutritional Intervention, Remote or In-Person
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Vermont Medical Center
Polyarthritis
Effect of Patient Education in Rheumatic Diseases
The purpose of this study is to explore the effect of patient education (PE) in patients with arthritis. PE has become a task that is dictated by law in Norway, and is increasingly used as an element in the treatment of patients…
- Trial name
- NCT00623922
- Testing
- Patient education with individual nurse consultations
- Where
- Norway
- Volunteers
- 141 people
- Sponsor
- Norwegian University of Science and Technology
Early Childhood Caries, Health Care Acceptability
Effectiveness and Acceptability of SDF Compared to ART for the Management of Early Childhood Caries
The goal of this clinical trial is to assess the acceptability and clinical effectiveness of Silver Diamine Fluoride (SDF) in comparison with Atraumatic Restorative Treatment (ART) in Early Childhood Caries (ECC) management at…
- Trial name
- SDF and ART (NCT06786975)
- Testing
- Silver Diamine Fluoride, Atraumatic Restorative Treatment
- Where
- Chile
- Volunteers
- 156 people
- Sponsor
- Universidad de La Frontera
Primary Open Angle Glaucoma, Ocular Hypertension
Laser-1st vs Drops-1st for Glaucoma and Ocular Hypertension
This is a randomized study with two treatment arms: 'initial Selective Laser Trabeculoplasty (SLT) followed by conventional medical therapy as required' ('Laser-1st') and 'medical therapy without laser ('Medicine-1st').
- Trial name
- LIGHT (NCT03395535)
- Testing
- Primary Selective Laser Trabeculoplasty Treatment Pathway, Primary Medical Treatment Pathway
- Where
- United Kingdom
- Volunteers
- 718 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Atrial Fibrillation Paroxysmal
Physiotherapist-led Exercise Within Cardiac Rehabilitation and Paroxysmal Atrial Fibrillation and COVID-19.
Paroxysmal atrial fibrillation (AF) induce, in the affected patient, a prominent negative effect on health-related quality of life (HR-QoL) and physical fitness.
- Trial name
- NCT04600713
- Testing
- PT-X and IMT
- Sponsor
- Vastra Gotaland Region
Molar Incisor Hypomineralization
Clinical Evaluation of Resin Infiltration Treatment of MIH-affected Teeth in Pediatric Patients
The goal of this clinical trial is to examine the clinical success of different pre-treatments in resin infiltration therapy applied to the incisors of pediatric patients with Molar Incisor Hypomineralization (MIH) and to…
- Trial name
- NCT07469124
- Testing
- Resin Infiltration, Microabrasion Followed by Resin Infiltration, Air Abrasion Followed by Resin Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Inonu University
Necrotizing Soft Tissue Infection, Necrotizing Fasciitis
Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled Trial
The purpose of this study is to estimate the effect of intravenous polyspecific immunoglobulin G (IVIG) compared with placebo (saline) on the patient-reported outcome measure Physical Component Summary Score (PCS) of the SF-36 in…
- Conditions
- Necrotizing Soft Tissue Infection, Necrotizing Fasciitis, Gas Gangrene, Fournier Gangrene
- Trial name
- INSTINCT (NCT02111161)
- Testing
- IVIG (Privigen), Saline 0.9%
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Anders Perner
Septic Shock
Life After Pediatric Sepsis Evaluation
Sepsis represents the leading cause of childhood mortality worldwide. However, as distinct from adult medicine, there exists a large knowledge gap regarding long term health related quality of life (HRQL) and functional status…
- Trial name
- LAPSE (NCT01415180)
- Where
- 11 sites in United States
- Volunteers
- 389 people
- Sponsor
- Seattle Children's Hospital
Cerebral Palsy, Quality of Life
Health Related Lifestyle and Quality of Life in Children With Cerebral Palsy
The primary aim of this study is assessing physical activity, the quality of sleep and health related quality of life in children with cerebral palsy, and parenting stress of caregivers of the children with cerebral palsy in…
- Conditions
- Cerebral Palsy, Quality of Life, Physical Activity, Physical Disability
- Trial name
- NCT03277027
- Testing
- interventional study
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- The Catholic University of Korea
Thyroid Diseases, Pregnancy Related
Mapping Health-related Quality of Life in Pregnant Women With Thyroid Disease.
Natural thyroid function changes during pregnancy. In up to tens of percent of pregnant women, these changes can lead to pathological fluctuations in hormone and antibody production.
- Conditions
- Thyroid Diseases, Pregnancy Related, Quality of Life
- Trial name
- ThyPreQol2020 (NCT04167423)
- Where
- 7 sites in Czechia
- Volunteers
- 253 people
- Sponsor
- Value Outcomes Ltd.
Irreversible Pulpitis
Post Operative Pain and Oral Health Related Quality of Life Following Pulpotomy VS Extraction of Permanent First Molar
The goal of this clinical trial is to compare between post operative pain and oral health related quality of life in participants receiving two treatments for first permanent mandibular molars with poor prognosis.
- Trial name
- NCT06420583
- Testing
- MTA pulpotomy, Extraction
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Epilepsy
A Novel Social Emotional Learning Curriculum for Youth With Epilepsy
Youth with epilepsy (YWE) are significantly more likely than their peers without epilepsy to experience isolation, interpersonal victimization, and low relationship satisfaction. This is a serious health concern.
- Trial name
- NCT06427967
- Testing
- Project Dream Team
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Boston Medical Center
Heart Transplant Patients, Kidney Transplant Patients
Multidisciplinary Non-Pharmacological Intervention to Improve Quality of Life in Solid Organ Transplant Recipients
This is a single-center interventional study aimed at evaluating the feasibility of a multidisciplinary non-pharmacological approach based on acupuncture, telerehabilitation-based physical rehabilitation, and brain health…
- Conditions
- Heart Transplant Patients, Kidney Transplant Patients, Lung Transplant, Liver Transplanted Patients
- Trial name
- TAO (NCT07870811)
- Testing
- Acupuncture, Telerehabilitation-Based Physical Rehabilitation, Psychological Support Program
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
Peri Implantitis
Quality of Life and Related Factors in People With Peri-Implantitis
This single-center cross-sectional observational study evaluated oral health-related quality of life and its relationship with patient- and implant-level characteristics in adults with peri-implantitis.
- Trial name
- NCT07761403
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Suleyman Demirel University
Well Being
Validation of the Shared Happiness Index in Multidisciplinary Primary Care Practices ( Be aPi )
Multi-professional primary care practices (Maisons de Santé Pluriprofessionnelles, MSP) have expanded widely in France over the last decade to respond to increasing healthcare needs, uneven distribution of physicians, and…
- Trial name
- Be aPi (NCT07431372)
- Where
- Reunion
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Cognitive Changes Due to Organic Disorder (Finding), Dementia
Gerontology Research Programme: The Singapore Longitudinal Ageing Studies (SLAS I & II)
The Gerontology Research Programme (GRP) in the National University Singapore's Department of Psychological Medicine, was formed to coordinate and facilitate the conduct of multi-disciplinary research on in a wide range of…
- Conditions
- Cognitive Changes Due to Organic Disorder (Finding), Dementia, Mild Cognitive Impairment, Frailty
- Trial name
- SLAS (NCT03405675)
- Testing
- SLAS 1, SLAS 2
- Where
- Singapore
- Volunteers
- 6,183 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Molar Incisor Hypomineralization
Change in OHRQOL Following Minimally Invasive Treatment of Anterior Teeth in Children With MIH
MIH is a prevalent developmental defect which has a negative impact on children's OHRQoL, especially when incisor opacities are present.
- Trial name
- NCT05727475
- Testing
- Minimal invasive restorative treatment, Fluoride gel application
- Where
- Jordan
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
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