Clinical trials: Healthy Control Group
QTc Evaluation, Electrocardiography
Influence of Moxifloxacin on QTc Interval in Healthy Subjects for Positive Control Validation
The aim of this study is to investigate the effect of moxifloxacin on the QT interval in order to gain information on the validity of results that will be collected during another clinical study testing riociguat in patients with…
- Trial name
- NCT01014247
- Testing
- Avelox (Moxifloxacin, BAY12-8039)
- Where
- 6 sites in Australia, Germany and 2 more
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
Balance Measures During Stance and Gait: Comparison of Gyroscopic Measurements of Trunk Sway
To investigate whether an extended version of Valedo®Motion (termed Sensoro for brand management purposes), has the same trunk sway measures similar normal reference values of SwayStar.
- Trial name
- NCT02509455
- Where
- Switzerland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy Volunteers
Annual Study to Investigate Influenza Vaccine Due to New Virus Strains for the 2007/2008 Influenza Season in Europe
Influenza (flu) viruses change continuously, therefore also the parts of viruses used in influenza vaccines can vary from year to year.
- Trial name
- NCT00479921
- Testing
- Trivalent influenza subunit vaccine
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Solvay Pharmaceuticals
Atopic Dermatitis
A Phase 1 Trial of OPA-15406 Ointment in Healthy Adult Male Subjects
To assess the safety (especially skin findings) and pharmacokinetics by applying 0.3%, 1%, or 3% formulation of 5g OPA-15406 ointment to a 1000 cm2 area as a single-dose and as a multiple-dose twice daily for 2 weeks in Japanese…
- Trial name
- NCT02334787
- Testing
- 0.3% OPA-15406 Ointment, 1% OPA-15406 Ointment, 3% OPA-15406 Ointment
- Where
- Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Post-prandial Glycaemic Response, Satiety
Effect of Peas in Muffins on Blood Glucose and Appetite Control
This study is part of a group of studies whose overall goal is to accurately define the physiochemical and structural effects of pea varieties and relate these to blood glucose attenuation and appetite related sensations in…
- Trial name
- PEA3 (NCT03306706)
- Testing
- Whole pea muffins, Split pea muffins, Wheat muffins
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St. Boniface Hospital
COVID-19 Prevention
Clinical Trial to Assess Safety and Immunogenicity of Gam-COVID-Vac Combined Vector Vaccine for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Сov-2) Infection
Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Centre Phase II/III Adaptive Clinical Trial to Assess the Safety and Immunogenicity of Gam-COVID-Vac Combined Vector Vaccine for SARS-Сov-2 Infection in Indian…
- Trial name
- NCT04640233
- Testing
- Gam-COVID-Vac
- Where
- 23 sites in India
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy
A Study to Test How Well Different Doses of BI 1584862 Are Tolerated by Healthy Men
The main objectives of this trial are to investigate safety, tolerability, and pharmacokinetics of BI 1584862 in healthy male subjects following administration of multiple rising doses.
- Trial name
- NCT06006598
- Testing
- BI 1584862, midazolam
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Cognitive Fatigue
Immersive VR Environments to Induce and Evaluate Cognitive Fatigability
Background: Immersive virtual reality (VR) technology is used by researchers to measure how people respond to complex stimuli in a controlled environment.
- Trial name
- NCT04883359
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Healthy
The Effect of an mHealth Intervention on Physical Activity and Nutrition: the FutureMe Trial
This study is a randomized controlled trial (RCT) which investigates the effect of a Future-Self Avatar intervention (FutureMe App) on physical activity (PA) and nutrition.
- Trial name
- NCT04505124
- Testing
- FutureMe App, Conventional TrackingApp
- Where
- Switzerland
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Annette Mönninghoff
Control of Frontal Plane Biomechanics, Patellofemoral Pain Syndrome
Impact of Hip Activation Compared to Hip Plus Balance Training on the Forward-Step-Down Test
The purpose of this research is to determine the impact of a hip activation home exercise program (HEP) compared to a hip activation + single leg balance HEP on performance of the Forward-Step-Down Test (FSDT) in healthy females.
- Trial name
- NCT06298903
- Testing
- Hip Activation, Hip activation + Single leg balance
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Pancreatic Cancer, Chronic Pancreatitis
Biospecimens for Identification of Diseases of the Pancreas.
This proposed project is designed to collect data and specimens from patients/subjects presenting to the University of Michigan with a disease affecting the pancreas (or specific control populations).
- Conditions
- Pancreatic Cancer, Chronic Pancreatitis, Type II Diabetes, Pancreatic Cysts
- Trial name
- SPORE-PANC (NCT01392027)
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 712 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy
Electrophysiological Effects of Tipranavir Co-administered With Ritonavir on the QT Interval in Healthy Female and Male Subjects
To demonstrate that tipranavir (TPV) co-administered with ritonavir (RTV) does not affect the QT interval more than placebo co-administered with ritonavir
- Trial name
- NCT02248883
- Testing
- TPV low, Moxifloxacin, TPV high
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study to Evaluate the Effect of Mipomersen on Cardiac Repolarization Conducted in Healthy Subjects
To assess the electrocardiogram (ECG) effects of mipomersen administered as a 200-mg subcutaneous (SC) therapeutic and a 200-mg intravenous (IV; [2-hour infusion]) supra-therapeutic dose relative to placebo in healthy adult male…
- Trial name
- NCT01090661
- Testing
- mipomersen sodium, moxifloxacin hydrochloride (Avelox®)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kastle Therapeutics, LLC
Rotavirus Infection
Safety and Preliminary Immunogenicity Study of Inactivated Vaccine for Prevention of Rotavirus Infection
This study is a randomized, double-blinded, placebo-controlled, Phase 1, dose-escalation study to evaluate the safety, reactogenicity and immunogenicity of Inactivated Rotavirus Vaccine (IRV) performed in healthy adult (aged…
- Trial name
- NCT04626856
- Testing
- Low dosage IRV on a 0- and 28-day schedule, Medium dosage IRV on a 0- and 28-day schedule, High dosage IRV on a 0- and 28-day schedule
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Invasive Group B Streptococcus (GBS) Disease
A Phase I, Randomized, Single-blind, Controlled, Single Center Study to Evaluate the Safety and Immunogenicity of a Dose Range of Glycoconjugate Antigen Vaccine of Group B Streptococcus in Healthy Women 18- 40 Years of Age
The goals of the proposed study are to evaluate the safety, tolerability and immunogenicity of a GBS vaccine. Previous studies suggest that immune responses against GBS can protect humans from infection.
- Trial name
- NCT00645346
- Testing
- GBS glycoconjugate vaccine
- Where
- Switzerland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Ocular Infection
A Phase 2, Open-Label, Randomized, Parallel Group, Placebo-Controlled, Single-Center Study to Assess Anti-microbial Efficacy and Safety of DCN01 Compared to Unisol® Following Topical Periocular Administration in Healthy Volunteers
This proof-of-concept study evaluates the clinical efficacy and safety of DCN01 in prepping of the periocular region.
- Trial name
- NCT01853722
- Testing
- DCN01, Unisol
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Deacon Biosciences, Inc.
Lifestyle, Healthy, Weight Management
Implementing Strategies for Eating Behaviour Modification Based on Portion Control
This is a pre-post intervention study designed to evaluate the feasibility of a self-applied weight management intervention based on portion control.
- Conditions
- Lifestyle, Healthy, Weight Management, Behavior Change
- Trial name
- PORTIONS-4 (NCT06519539)
- Testing
- PORTIONS-4 behaviour change strategies
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Healthy
A Study to Investigate the Effect of JNJ-64565111 on Cardiac Repolarization (Corrected QT Interval) Compared With Placebo in Healthy Adults: a Thorough ECG Study Employing Placebo, JNJ-64565111, and a Positive Control (Moxifloxacin)
The purpose of this study is to assess the effects on placebo-corrected change from baseline QT interval corrected for individual heart rate (QTcI) of JNJ-64565111 close to steady state on Day 26 and on electrocardiogram…
- Trial name
- NCT03606057
- Testing
- JNJ-64565111, Moxifloxacin
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Environmental Awareness, Ecological Footprint
Effect of AI-Based Image Generation on Children's Ecological Footprint Awareness
The aim of this study is to examine the effect of artificial intelligence-based image generation on children's ecological footprint awareness.
- Conditions
- Environmental Awareness, Ecological Footprint, Healthy Children
- Trial name
- NCT07898527
- Testing
- AI-Based Image Generation Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Healthy
Single Ascending Dose Study of Lu AF76432 in Healthy Young Men
The purpose of this study is to investigate safety, tolerability and pharmacokinetics of the drug Lu AF76432 given as single oral ascending doses to healthy young men
- Trial name
- NCT03531229
- Testing
- Lu AF76432
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
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