Clinical trials: Heat Stress
Hyperthermia, Heat; Weather
Protective Cooling Measures to Safeguard Elderly People From Dangerous Summer Heat
With the increasing incidence and severity of extreme heat events accompanying climate change, there is an urgent need for sustainable cooling strategies to protect heat-vulnerable older adults, who are at increased risk of…
- Conditions
- Hyperthermia, Heat; Weather, Aging, Type2 Diabetes
- Trial name
- NCT05274009
- Testing
- No cooling (control), Recommended cooling, Hybrid cooling
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Heat Stress, Heat
Study of Biomarkers of Heat Tolerance and Recovery During Ultra-endurance Exercise
Military personnel are called upon to serve in hot, dry or humid climates, which places great demands on their ability to tolerate heat. Induced heat stress can impair performance and lead to pathologies.
- Trial name
- PENTHERE (NCT05921864)
- Testing
- Passive heat exposure, Active heat exposure
- Where
- France
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Aging Well, Walking, Difficulty
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
To test the hypothesis that home-based leg heat therapy improves functional capacity, vascular function, and exercise hyperemia in older adults.
- Conditions
- Aging Well, Walking, Difficulty, Hyperemia
- Trial name
- NCT05706181
- Testing
- Home-based leg heat therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Heat Stress
Comparison of a Novel Condensed Heat Acclimation Programme With a Traditional Longer-term Heat Acclimation Programme
Repeated exposure to heat in a laboratory setting (acclimation) elicits a range of adaptations, which reduce heat illness risk and increase work capacity in the heat.
- Trial name
- NCT05600452
- Testing
- Heat acclimation
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Heat Illness, Quality of Life
Structural Heat Adaptation and Education in Urban Setting
This study aims to understand whether simple, low-cost interventions, such as improved home cooling, practical advice, and minor home modifications, can help protect people's health and improve quality of life during periods of…
- Trial name
- SHAPES (NCT06991543)
- Testing
- Community education and awareness, and personal lifestyle and cooling behavior modification, Participatory local structural and environmental heat mitigation solutions
- Where
- Pakistan
- Volunteers
- 7,128 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Aging, Heat Stress
Physiological Responses in Young and Older Adults During a Prolonged Simulated Heatwave
Climate change not only affects the planet's natural resources, but also severely impacts human health. An individual's ability to adequately cope with short- or long-term increases in ambient temperature is critical for…
- Conditions
- Aging, Heat Stress, Physiological Stress
- Trial name
- HW1 (NCT04353076)
- Testing
- Simulated heatwave exposure, Simulated heatwave exposure with mid-day cooling
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Hyperthermia, Cocaine Use
Intranasal Cocaine and Temperature Regulation During Exercise
Assess the effects of intranasal cocaine on temperature regulation and whole-body sweat rate during exercise in warm environmental conditions.
- Conditions
- Hyperthermia, Cocaine Use, Exercise
- Trial name
- NCT05809453
- Testing
- Cocaine, Lidocaine
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Aging, Hyperthermia
Heat Waves and the Elderly - Cooling Modalities
The purpose of this study is to assess how well cooling modalities work in reducing cardiovascular stress of the elderly to heat wave conditions
- Trial name
- NCT05484739
- Testing
- Water Spray, Fan, Water Spray and Fan
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hyperthermia
Sauna Detoxification Study: Pilot Feasibility
The goal of this study is to assess the feasibility of the approach, conduct a dose-finding investigation, and obtain pilot data on hyperthermia via sauna to apply in follow-up trials in the assessment of human chemical body…
- Trial name
- NCT01576822
- Testing
- This protocol will utilize a sauna as the primary method of detoxification.
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bastyr University
Neoplams, PIV Catheter Insertion
The Effect of Isometric Exercise and Dry Heat Application on PIVC
Purpose: This study was conducted to evaluate the effect of isometric exercise and dry heat application technique on venous fullness and vein visibility in cancer patients.
- Trial name
- NCT07704502
- Testing
- Isometric exercise, Dry heat application
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Inonu University
Hyperthermia, Fatigue; Heat
Simulation of Consecutive Day Shift Work
The purpose of this study is to determine differences in physiological recovery between two consecutive days of simulated fire suppression work.
- Trial name
- NCT04625634
- Testing
- 2 days of work heat stress
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Heat Stress, Physiological Stress
Influence of Indoor Humidity on Physiological Strain in Older Adults During a Simulated Heat Wave
Laboratory-based studies show that exposure to high humidity can worsen the effects of heat stress in young and older adults by impeding sweat evaporation - the main mechanism by which the human body cools itself.
- Trial name
- NCT06842953
- Testing
- Simulated indoor overheating
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Inflammation, Aging
Adaptive Stress Response: The Hot Yoga Study
This is a small intervention study which is aimed at characterizing what is known as the adaptive stress response (also know as "hormesis") in women aged 30-45 years.
- Conditions
- Inflammation, Aging, Depression, Anxiety
- Trial name
- NCT06395376
- Testing
- Bikram Hot Yoga Intervention, Hot Yoga Washout
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Hyperthermia
The Effectiveness of Emergency Room Protocols for Treating Hyperthermia
This study will help us as scientists and clinicians understand how effective commonly used cooling protocols in emergency departments are and which of the protocols is the most effective.
- Trial name
- EDCP (NCT07433036)
- Testing
- Passive cooling, Cooling packs, Ice sheets
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs