Clinical trials: Heat Stress Disorders
Neoplams, PIV Catheter Insertion
The Effect of Isometric Exercise and Dry Heat Application on PIVC
Purpose: This study was conducted to evaluate the effect of isometric exercise and dry heat application technique on venous fullness and vein visibility in cancer patients.
- Trial name
- NCT07704502
- Testing
- Isometric exercise, Dry heat application
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Inonu University
Fibromyalgia
Hyperthermia in Fibromyalgia Syndrome
This study will examine the effectiveness of water-filtered whole-body hyperthermia during an outpatient setting in patients with fibromyalgia.
- Trial name
- HYPAIN (NCT05135936)
- Testing
- Hyperthermia Group
- Where
- Germany
- Volunteers
- 41 people
- Sponsor
- Jost Langhorst
Hyperthermia
Comparison of Fatigue in Varying Hot Environments
The purpose of this study is to determine the impact of varying hot environments on physiological and perceptual fatigue during work.
- Trial name
- NCT04624919
- Testing
- Hot/Dry, Warm/Humid
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Locally Advanced Rectal Carcinoma
Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer
The goal of this clinical trial is to investigate if the addition of modulated electro-hyperthermia (mEHT) improves tumor down-staging and pathological response in adult patients (20 years and above) with locally advanced rectal…
- Trial name
- mEHT (NCT07372300)
- Testing
- Hyperthermia
- Where
- Taiwan
- Volunteers
- 126 people
- Sponsor
- Shih-Kai Hung
Knee Arthropathy
Laser + Cryo-thermal Therapy Following Total Knee Replacement Surgery
Objective To investigate the effectiveness of the use of the QMD Helios Laser device in association with standard rehabilitation therapy in reducing inflammatory symptoms in patients following total knee replacement.
- Trial name
- NCT04183673
- Testing
- Laser therapy-cryo thermal therapy, Usual care
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Heat Stress, Kidney Injury
Does Probiotic Supplementation Prevent Kidney Injury During Strenuous Physical Exercise?
Severe heat strain arising from intense physical work under climate conditions that does not allow sufficient heat dissipation may lead to heat stroke.
- Trial name
- NCT04985292
- Testing
- Probiotic, Lactobacillus
- Where
- Sweden
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Colorectal Neoplasm, Colorectal Cancer
Perioperative Systemic Therapy for Isolated Resectable Colorectal Peritoneal Metastases
This is a multicentre, open-label, parallel-group, phase II-III, superiority study that randomises patients with isolated resectable colorectal peritoneal metastases in a 1:1 ratio to receive either perioperative systemic therapy…
- Conditions
- Colorectal Neoplasm, Colorectal Cancer, Colorectal Neoplasms Malignant, Colorectal Carcinoma
- Trial name
- CAIRO6 (NCT02758951)
- Testing
- Perioperative systemic therapy, Perioperative CAPOX-bevacizumab, Perioperative FOLFOX-bevacizumab
- Where
- 9 sites in Belgium, Netherlands
- Volunteers
- 358 people
- Sponsor
- Koen Rovers
Therapeutic Hyperthermia, Thermotherapy
Evaluation of a Polymeric Plate Derived From Castor Oil to Thermotherapy
The objective of this work is to evaluate, from volunteers viewpoint, the usability, comfort, appearance, weight, superficial temperature, and other characteristics of a polymeric plate derived from castor oil developed to…
- Conditions
- Therapeutic Hyperthermia, Thermotherapy, Polymers
- Trial name
- NCT01100541
- Testing
- Polymeric plate
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Rectal Cancer
Hyperthermia With Chemoradiotherapy in Rectal Cancer
The goal of this clinical trial is to evaluate the efficacy of deep regional hyperthermia in the context of radiochemotherapy followed by consolidation chemotherapy in locally advanced rectal cancer.
- Trial name
- ARO 2024-13 (NCT06831981)
- Testing
- Hyperthermia, Radiotherapy, Chemotherapy with 5-fluorouracil
- Where
- 2 sites in Germany
- Volunteers
- 264 people
- Sponsor
- University Hospital Tuebingen
Heat Stress, Physiological Stress
Physiological Strain in Young Adults During a Simulated Heat Wave
The likelihood of exposure to overheated indoor environments is increasing as climate change is exacerbating the frequency and severity of hot weather and extreme heat events.
- Trial name
- NCT06618352
- Testing
- Simulated indoor overheating exposure
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Malignant Hyperthermia
Malignant Hyperthermia Registry and Genetic Testing
The purpose of this study is to to determine the penetrance of known and probable pathogenic variants in genes and the factors that contribute to penetrance in a population of children and adults in the United States exposed to…
- Trial name
- NCT02964481
- Testing
- Whole exome sequencing
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Physiological Stress, Heat Stress
Validation of Heat Stress Limit Values for the Athletic Performance
Three male and three female semi-professional athletes, ranging in age from 22 to 27, participated in a study that was done at Lund University in Sweden to examine their physiological responses.
- Conditions
- Physiological Stress, Heat Stress, Sports Injury, Heat Stress, Exertional
- Trial name
- HSL-AP (NCT06084494)
- Testing
- analytical determination and interpretation of heat stress using calculation of the Predicted Heat Strain and Wet Bulb Globe Temperature
- Where
- Pakistan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of the Punjab
Endothelial Dysfunction
Effect of Local Heat Stress Via Leg Bath on Artery Function
Arteries are flexible in their structure and function and change in response to a variety of factors. Endothelial cells, are the skin type cells that form a layer inside arteries, and they are very important for arterial health.
- Trial name
- HEAT (NCT03618524)
- Testing
- Lower limb hot water immersion
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- McMaster University
COPD, Aging
Heat Waves and the Elderly With COPD
The purpose of this study is to investigate thermoregulatory responses in older individuals with COPD.
- Conditions
- COPD, Aging, Hyperthermia
- Trial name
- NCT06295523
- Testing
- Water Spray, Control
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Texas Southwestern Medical Center
Aging, Hyperthermia
Cardiovascular Responses to Heat Waves in the Elderly
The purpose of this study is to assess the cardiovascular responses of the elderly to heat wave conditions
- Trial name
- NCT04538144
- Testing
- Hot and Humid Trial, Hot and Dry Trial
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Gastrointestinal Tumor
Hyperthermia Combined With Immune Checkpoint Inhibitor Therapy for Advanced Gastrointestinal Tumours
Gastrointestinal tumours (GITs) are the most common and fatal cancers worldwide; 96% of GITs show the microsatellite-stable (MSS)/proficient mismatch repair (pMMR) phenotype, and these tumours have a poor response to immune…
- Trial name
- HEAIS001 (NCT06022692)
- Testing
- Water-filtered infrared A radiation whole-body hyperthermia (HECKEL 3000MT-4T, Germany), tislelizumab (BeiGene, China) combined with PD-1 inhibitor
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Pengyuan Liu
Diabetes Mellitus, Heat Stress
Efficacy and Safety of Modified ORS(Amr and Khulood ORS) in Diabetic Pilgrims During Hajj
Heat stress and dehydration are significant risks for diabetic pilgrims during the Hajj, often leading to severe complications. Standard Oral Rehydration Salts (ORS) are effective for rehydration but may cause hyperglycemia in…
- Trial name
- AA-HAMS-ORS (NCT07618702)
- Testing
- Modified Oral Rehydration Salts (ORS)( Amr and khulood ORS), Standard Oral Rehydration Salts (ORS)
- Where
- Saudi Arabia
- Volunteers
- 200 people
- Sponsor
- Amr kamel khalil Ahmed
Tonsillitis
PEAK PlasmaBlade TnA Versus Traditional Electrosurgery in Subcapsular Tonsillectomy
The objective of this clinical study is to evaluate the operative performance of the PEAK PlasmaBlade® TnA during subcapsular tonsillectomy; to monitor and record post-operative clinical outcome variables; and to compare these…
- Trial name
- PRECISE (NCT01193556)
- Testing
- PEAK PlasmaBlade TnA, Traditional Electrosurgery with scalpel
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Medtronic Surgical Technologies
Breast Neoplasms
Immunostimulating Interstitial Laser Thermotherapy in Breast Cancer
Thermotherapy is a technology aiming at destroying tissue, for example tumor tissue. Immunostimulating Interstitial Laser Thermotherapy (imILT) is a specific form of thermotherapy, which, in addition to destroying tumor tissue…
- Trial name
- NCT03039127
- Testing
- Immunostimulating Interstitial Laser Thermotherapy
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- Clinical Laserthermia Systems AB
Borderline and Locally Advanced Pancreatic Cancer
A Prospective Study of Concurrent Hyperthermia, Chemotherapy and Radiotherapy in Borderline and Locally Advanced Pancreatic Cancer (PANHEAT)
The project proposes a prospective multicenter study to evaluate the incorporation of deep regional hyperthermia into the standard of care neoadjuvant chemotherapy (mFOLFIRINOX/NABPACLITAXEL) followed by radiotherapy in…
- Trial name
- PANHEAT (NCT07839676)
- Testing
- Hyperthermia plus neoadjuvant chemotherapy/radiotherapy Arm Description: Hyperthermia plus neoadjuvant chemotherapy (mFOLFIRINOX/nab Paclitaxel) followed by a) surgically resectable: Hyp
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Fernando Pessoa Canarias University