Clinical trials: Helping Behavior
Heart Failure.
Optimizing Continuous-flow Left Ventricular Assist Device Settings and Identification of Pump Malfunction - A Comparative Study of Echocardiography and Invasive Hemodynamics
The purpose of the trial is to identify factors which can be used as guidance when optimizing continuous-flow left ventricular assist device (CF-LVAD) settings.
- Trial name
- NCT01851889
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Differentiated Thyroid Cancer (DTC), Robotic Assistance
Robotic Surgery Via Bilateral Axillo-breast Approach for Relatively Low-risk Papillary Thyroid Carcinoma With Lateral Cervical Lymph Node Metastasis: a Safe and Effective Cosmetic Procedure in the Context of Prevalent Thyroid Ultrasound Screening
The goal of this observational study is to learn the efficacy, cosmetic effectiveness and safety of robotic modified radical neck dissection in well-selected cases, through direct comparison with conventional open surgery in…
- Trial name
- NCT07229859
- Where
- China
- Volunteers
- 332 people
- Sponsor
- Ruijin Hospital
Dental Implant
Accuracy of Dental Implant Position Robotic Assistance, Dynamic Navigation, or Static Guide?
For free hand dental implant placement, a key difficulty is to accurately control the position. Improving precision of dental implant placement is considered important for safety and efficacy of tooth replacement with dental…
- Trial name
- NCT05892406
- Testing
- Static guide, Dynamic navigation, Robotic system
- Where
- 2 sites in China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Inflammatory Bowel Diseases, Crohn Disease
A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and PerSiStence With IBD Therapy
The investigators hypothesize that use of a remote monitoring digital health system that supports medication taking and monitoring of symptoms will improve adherence, clinical outcomes, and decrease healthcare utilization…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- ASSIST (NCT05316584)
- Testing
- Remote monitoring
- Where
- 5 sites in United States
- Volunteers
- 123 people
- Sponsor
- University of Maryland, Baltimore
Lung Disease Chronic
Powered Assist to Improve Ambulation in Severe Lung Disease
Chronic respiratory disease (CRD) is among the most prevalent and growing diseases worldwide with disabling consequences. Many with a compromised respiratory system cannot support the metabolic energy demands of walking causing…
- Trial name
- REVIVE (NCT03790644)
- Testing
- exoskeleton assist
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- West Park Healthcare Centre
ARDS
Comparison of Volume Assist Control, Dual Mode and Airway Pressure Release Ventilation.
The aim of the COMIX-R study is to assess the short term physiological effects of 3 ventilation strategies for adult patients with ARDS admitted to intensive care unit
- Trial name
- COMIX-R (NCT04196738)
- Testing
- ventilation strategy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Osteoarthritis
Do We Need Computer Assistance To Improve the Survival of Primary Total Knee Arthroplasty. A Minimum Ten Years Follow-up
The investigators asked: (1) Do computer-assisted total knee arthroplasty (TKAs) provide better alignment and clinical function? (2) Do computer-assisted TKAs provide better survivorship of implants and less complication? and (3)…
- Trial name
- NCT01520571
- Testing
- Non-Computer Assistance TKA, Computer Assistance TKA
- Where
- South Korea
- Volunteers
- 520 people
- Sponsor
- Ewha Womans University
Aging, Walking
Effects of a Powered Lower-Limb Exoskeleton on Walking Performance in Older Adults
The goal of this clinical trial is to learn whether a powered wearable lower-limb exoskeleton can improve walking performance in independently ambulatory older adults aged 65 to 75 years.
- Conditions
- Aging, Walking, Physical Function, Mobility Limitation
- Trial name
- E-WALK (NCT07633093)
- Testing
- Powered Lower-Limb Exoskeleton
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hunan Normal University
Reproductive Techniques, Assisted
Clinical Trial Comparing Endometrial Transformation With Subcutaneous Progesterone Versus Intramuscular Progesterone
Study the endometrial predecidualization by using subcutaneous progesterone 25 mg/day versus intramuscular progesterone 50 mg/day, to determine whether there are differences in the endometrial transformation and endometrial…
- Trial name
- NCT02567552
- Testing
- Subcutaneous progesterone, Intramuscular progesterone
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- IVI Barcelona
DSA, Bleeding
AI Assistance for Detecting Active Bleeding During DSA Procedures
Clinically, DSA-VDet can continuously indicate suspected bleeding regions throughout a complete angiographic sequence and provide a second-reader opinion to the operator.
- Conditions
- DSA, Bleeding, AI (Artificial Intelligence), Hemorrhage
- Trial name
- NCT07824739
- Testing
- DSA-VDet v1.0
- Where
- China
- Volunteers
- 1,324 people
- Sponsor
- Zhongda Hospital
Ventricular Dysfunction, Left
Characterization of the Plasma Proteome Following Left Ventricular Assist Device Implantation
The purpose of this study is to characterize changes in the plasma proteome over time following left ventricular assist device (LVAD) implantation.
- Trial name
- NCT02428894
- Testing
- LVAD
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Cataract
A Study of Cataract Surgery With the Femtosecond Laser
The purpose of this study is to evaluate the feasibility of using the Femtosecond Laser System to perform surgical maneuvers during cataract extraction surgery.
- Trial name
- NCT00922571
- Testing
- FS Laser Surgery, FS Laser System
- Volunteers
- 100 people
- Sponsor
- Abbott Medical Optics
Endothelial Cells, Exercise Tolerance
Markers of Endothelial Function and Exercise CapaciTy in Patients With Left Ventricular Assist Devices (EFECT LVAD)
This is a non-randomized feasibility study of endothelial function, exercise capacity, and outcome following pre-left ventricular assist device (LVAD)therapy and cardiac transplant.
- Trial name
- EFECT-LVAD (NCT01233037)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
LVAD Caregivers, LVAD (Left Ventricular Assist Device)
Compassion Strikes Back
Research has shown that LVAD patients and their caregivers typically experience increased mental health concerns and decreased quality of life following LVAD implantation and hospital discharge.
- Conditions
- LVAD Caregivers, LVAD (Left Ventricular Assist Device), Quality of Life (QOL), Self-Compassion
- Trial name
- NCT06988995
- Testing
- Information, Meeting
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Congestive Heart Failure
The Epidemiology of Bleeding and Clotting in Patients Undergoing Heart Transplantation, Coronary Artery Bypass Graft Surgery,or Implantation of Left Ventricular Assist Devices
The purpose of this study is to obtain data or information on how blood clotting factors are activated during open heart surgery.
- Trial name
- NCT01481012
- Where
- 13 sites in United States
- Volunteers
- 94 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Exoskeleton Device
Evaluation of Trunk Assistance Exoskeleton
The goal of this interventional study is to evaluate the effect of three different designs of trunk assistance exoskeletons on cumulative lumbar load, trunk extensors' muscular fatigue and comfort in healthy volunteers.
- Trial name
- NCT07084974
- Testing
- Adjustment and practice session, No trunk assistance, Uplift Lite exoskeleton
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TOPMED
Critically Ill
Mechanical Insufflation-Exsufflation (Cough Assist) in Critically Ill Adults
The goal of this randomized feasibility trial is to evaluate the feasibility of Mechanical Insufflation-Exsufflation (MI-E) in invasively ventilated critically ill patients.
- Trial name
- ACACIA (NCT06027008)
- Testing
- Mechanical Insufflation-Exsufflation
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Preterm Birth
Oxygen Assist Module in Preterm Infants on High Flow Nasal Cannula Support.
Oxygen treatment is common in babies born early (preterm) and requiring intensive care. Having too much or too little oxygen can increase the risk of damage to the eyes and lungs, and contribute to death or disability.
- Trial name
- ROAM (NCT04687618)
- Testing
- High Flow Nasal Cannula withAutomatic control of FiO2 using OAM, High Flow Nasal Cannula with manual control of FiO2
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Neonatal Respiratory Distress Syndrome, Prematurity
Breathing Variability and NAVA in Neonates
The current study is a crossover trial, aiming at evaluating the effect of NAVA -NIV compared to Nasal Intermittent Positive Pressure Ventilation (PC-NIV) at the same level of peak inspiratory pressure, in terms of…
- Trial name
- BRAVe NANO (NCT04000568)
- Testing
- Respiratory support: NAVA -NIV and PC-NIV
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Heart Failure
LVAD Conditioning for Cardiac Recovery
The purpose of this study is to investigate the potential recovery of heart function in end-stage heart failure patients supported with a Left Ventricular Assist Device (LVAD) through applying a myocardial conditioning protocol.
- Trial name
- NCT03238690
- Testing
- Controlled Cardiac Reloading through LVAD Speed Adjustment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- STAVROS G DRAKOS
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