Clinical trials: Hematologic
Newborn; Vitality, Iron Deficiency Anemia
The Importance of Delayed Cord Clamping
After birth, the umbilical cord is usually clamped and separated from the placenta within the first 30 seconds. Although the exact time to clamp the umbilical cord is unknown, allowing placental transfusion after birth has many…
- Trial name
- NCT06405867
- Testing
- delayed cord clamping (> 60 sec)
- Where
- Turkey (Türkiye)
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Anemia, Anemia, Iron Deficiency
Iron Deficiency Anemia and Non-iron Deficiency Anemia in Pregnancy in India
This is a sub-study nested into the existing NICHD Global Network for Women's \& Children's Health Research Maternal Newborn Health (MNH) registry that is a prospective, observational population-based registry in Eastern…
- Conditions
- Anemia, Anemia, Iron Deficiency, Anemia of Pregnancy
- Trial name
- IDA & NIDA (NCT04708665)
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Anemia, Iron Deficiency, Iron Overload
Heme and Non-heme Iron Intakes, Gut Microbiota, and Influence on Host Iron Absorption
The FeMicrobiome study will evaluate gut microbiome features and their relationships with dietary iron absorption in healthy adults.
- Trial name
- FeMicrobiome (NCT06146608)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cornell University
Acute Myeloid Leukemia
Application of Health Education Path of Traditional Chinese Medicine Nursin
To explore the effect of traditional Chinese medicine (TCM) health education standard path on the treatment of patients with acute myeloid leukemia (AML).
- Trial name
- NCT05563207
- Testing
- traditional Chinese medicine health education standard path, The contents of the health intervention mainly included:Graphic and text education, The contents of the health intervention mainly included:Language education
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shijiazhuang Pingan Hospital
Iron Deficiency, Anemia
Prevention of Iron Deficiency in 2nd Year of Life
Healthy babies(age 8-18 months) following a routine blood count, with no anemia or iron deficiency, will be randomly placed in two groups.
- Trial name
- NCT00479102
- Testing
- Ferripel-3 - iron polysaccharide complex for prevention
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Multiple Myeloma, Low-Grade Lymphoma
64Cu-LLP2A for Imaging Hematologic Malignancies
This phase of the protocol (protocol part B), seeks to evaluate the new formulation in healthy normal volunteers to confirm the new formulation provides comparable human dosimetry to which was seen and published in protocol part…
- Conditions
- Multiple Myeloma, Low-Grade Lymphoma, Follicular Lymphoma, Marginal Zone Lymphoma
- Trial name
- NCT06636175
- Testing
- 64Cu-LLP2A, PET/CT
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Gestational Diabetes Mellitus (GDM), Pregnancy Induced Hypertension (PIH)
mHealth Integrated Model of Hypertension, Diabetes and Antenatal Care in India and Nepal
Our research aims to address a critical gap in the provision of quality antenatal care (ANC) in India and Nepal, by developing and evaluating an intervention comprising of a tablet-based electronic decision support system (EDSS).
- Conditions
- Gestational Diabetes Mellitus (GDM), Pregnancy Induced Hypertension (PIH), Anemia
- Trial name
- NCT03700034
- Testing
- mHealth Integrated Model of Antenatal Care
- Where
- 6 sites in India, Nepal
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation of India
Chronic Lymphocytic Leukemia
Study of Immune Responses to Influenza Vaccination With or Without Imiquimod Application in Untreated CLL Patients
The purpose of the study is to determine whether it is possible to improve the immune response rate to 'flu vaccination in patients with chronic lymphocytic leukaemia (CLL).
- Trial name
- CLLIFVAC (NCT00596336)
- Testing
- Imiquimod cream, influenza vaccine
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Royal Bournemouth Hospital
Heart Failure, High Blood Pressure
BVA-200 vs BVA-100 Validation Study
The proposed study is a prospective, observational, investigator and patient blinded study comparing the results of blood volume measurement using the FDA-cleared Daxor BVA-100 device to the Daxor BVA-200 device.
- Conditions
- Heart Failure, High Blood Pressure, High Cholesterol, Anemia
- Trial name
- NCT06227819
- Testing
- BVA-200
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Daxor Corporation
Anemia
Periconceptional Iron Supplementation in Rural Bangladesh
The investigators hypothesize that periconceptional iron supplementation to married, nulliparous women in rural Bangladesh will significantly reduce anemia and improve hemoglobin concentrations before and during pregnancy.
- Trial name
- NCT00953134
- Testing
- Ferrous fumarate (iron), folic acid
- Where
- Bangladesh
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome
Multi-antigen Specific CD8+ T Cells With Decitabine and Lymphodepleting Chemotherapy for the Treatment of Patients With Relapsed or Refractory AML or MDS Following an Allogeneic Hematopoietic Cell Transplantation From a Matched Donor
This phase I trial tests the safety, side effects and best dose of NEXI-001 when given with decitabine and lymphodepleting chemotherapy in treating patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that…
- Conditions
- Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic Syndrome
- Trial name
- NCT06572631
- Testing
- Allogeneic CD8+ Leukemia-associated Antigens Specific T Cells NEXI-001, Biospecimen Collection, Bone Marrow Aspiration
- Volunteers
- healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Malaria, Anemia
Uganda Housing Modification Study
To explore housing modification as a malaria control intervention, and to assess the degree to which it may offer protection in moderate to high malaria endemicity settings, we propose a two-phase study evaluating epidemiological…
- Trial name
- UHMS (NCT04622241)
- Testing
- Eave Tubes, Eave Ribbons, Full House Screening
- Where
- Uganda
- Volunteers
- 2,422 people, healthy volunteers welcome
- Sponsor
- Infectious Diseases Research Collaboration, Uganda
Malaria, Anemia
Evaluation of a Comprehensive School Health Programme in Zambia
In Zambia, the health and well-being of children aged 5 to 14 has often been overlooked, leading to various health challenges affecting their development and education.
- Conditions
- Malaria, Anemia, Diarrhea
- Trial name
- NCT06560853
- Testing
- Comprehensive School Health Programme, Deworming and vitamin A supplementation delivery
- Where
- 6 sites in Zambia
- Volunteers
- 28,700 people, healthy volunteers welcome
- Sponsor
- London School of Economics and Political Science
Hematologic Malignancy
Exploratory Study of IMM01 for Injection in the Treatment of Refractory or Recurrent Hematologic Malignancy
This is a multi-center, open-label, dose-escalation and cohort-expansion phase I clinical study to evaluate the safety and tolerability, pharmacokinetics profile, efficacy and immunogenicity of IMM01 in subjects with refractory…
- Trial name
- NCT05860075
- Testing
- IMM01
- Where
- China
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- ImmuneOnco Biopharmaceuticals (Shanghai) Inc.
Sickle Cell Disease, Vitamin D Deficiency
High Dose Vitamin D Supplementation in Children With Sickle Cell Disease
Suboptimal vitamin D status is well reported in sickle cell disease (SCD) patients and associated with a negative impact on health-related quality of life (HRQL).
- Conditions
- Sickle Cell Disease, Vitamin D Deficiency, Health Related Quality of Life, Hand Grip Strength
- Trial name
- NCT06274203
- Testing
- Vitamin D3
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Infections, Streptococcal
Immunization of Children Between 8 Weeks and 2 Years of Age With GSK Pneumococcal Vaccine GSK1024850A
The aim of the study is to evaluate the immunogenicity, safety and reactogenicity of GSK Biologicals' pneumococcal conjugate vaccine GSK1024850A.
- Trial name
- NCT01175083
- Testing
- GSK1024850A (Synflorix), Tritanrix-HepB/Hib, Polio Sabin
- Where
- Burkina Faso
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sickle Cell Anemia Crisis
Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises?
The purpose of this study is to determine whether IV acetaminophen can decrease the need for subsequent opioid administration in the acute management of sickle cell crisis pain in the pediatric emergency room.
- Trial name
- NCT03541980
- Testing
- Acetaminophen, Normal saline
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Newark Beth Israel Medical Center
This Study Aimed to Evaluate the Impact of Fortified Biscuit Consumption on the Iron Status of School-aged Children in Rural Kaolack
Impact of the Consumption of Fortified Biscuits on the Iron Status of School-aged Children
This study aimed to evaluate the impact of fortified biscuit consumption on the iron status of school-aged children in rural Kaolack.
- Trial name
- NCT07041866
- Testing
- Fortified Biscuit with Local Iron-Rich Ingredients, Non-Fortified Biscuit
- Where
- Senegal
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- Universite du Sine Saloum Elhadj Ibrahima Niasse
Anemia, Iron Deficiency, Vitamin A Deficiency
Iron and Vitamin A in School Children
The WHO recommended intermittent iron supplementation as a strategy for prevention of anemia and iron deficiency among school age children.
- Conditions
- Anemia, Iron Deficiency, Vitamin A Deficiency, Cognitive Development, Helminthic Infection
- Trial name
- IronVitA (NCT04137354)
- Testing
- Intermittent iron supplement, High-dose Vitamin A supplement
- Where
- Ethiopia
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- University Ghent
Anemia, Iron Deficiency
Iron and Prebiotics Fortification in Kenyan Infants
Iron deficiency and anemia are health issues affecting mainly infants and women in developing countries. Iron deficiency in infancy can have long-lasting impact on cognitive and motor development of the child.
- Conditions
- Anemia, Iron Deficiency, Diarrhea, Malaria
- Trial name
- Iro'n'Pre (NCT02118402)
- Testing
- Fortified maize porridge
- Where
- Kenya
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
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