Clinical trials: Hematuria
Hematuria - Cause Not Known
Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.
This study includes adult patients who see a urologist because of blood in their urine. The amount is so small it can only be seen with a microscope. This is called microhematuria. There can be many reasons for microhematuria.
- Trial name
- CREDIBLE (NCT06394869)
- Testing
- Cxbladder Triage Plus
- Where
- 20 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Pacific Edge Limited
UTUC, UC (Urothelial Cancer)
Screening for Urological Malignancies Using a Urine Exfoliated Cell Fluorescence Assay in a Hematuria Population
This is a prospective, single-center diagnostic clinical study designed to evaluate the performance of a urine-based immunofluorescence cytology test for the detection of urological malignancies in patients presenting with…
- Trial name
- NCT07813260
- Where
- China
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Pain, Anxiety
Multimedia Information for Patients With Renal Biopsy
This study takes place in the Divisions of Nephrology. Patients undergoing renal biopsy were randomized to control group or multimedia information intervention group.
- Conditions
- Pain, Anxiety, Hematuria
- Trial name
- NCT04971057
- Testing
- multimedia information program of renal biopsy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Bladder Cancer
Detecting Bladder Cancer Using the UroMark Test.
DETECT I is a prospective multicentre observational diagnostic study to assess the performance of the UroMark assay to rule out bladder cancer in patients with haematuria.
- Trial name
- DETECT I (NCT02676180)
- Testing
- Group
- Where
- 2 sites in United Kingdom
- Volunteers
- 3,700 people
- Sponsor
- University College, London
Hematuria
Study on Risk Assessment for Patients With Microscopic Hematuria (Non-Visible Blood in Urine) Using a Urine Marker Test
The goal of this clinical study is to learn how well a urine test called Xpert® Bladder Cancer Detect (Xpert BC-D) can help doctors assess the risk of bladder cancer in people with non-visible blood in their urine (microscopic…
- Trial name
- UroDetect III (NCT07307300)
- Where
- Germany
- Volunteers
- 1,475 people
- Sponsor
- Christian Bolenz
Hematuria, Hydronephrosis
Influence of Transmission Season on Outcome of Treatment of Schistosoma Haematobium Infection in Mozambique
To assess the influence of seasonal variations in Schistosoma haematobium transmission on treatment outcome (morbidity and re-infection)
- Trial name
- NCT00231322
- Testing
- praziquantel
- Where
- Mozambique
- Volunteers
- 520 people
- Sponsor
- DBL -Institute for Health Research and Development
Bladder Cancer, Urothelial Carcinoma (UC)
Specimen Collection for Validation of UroAmp: A Next Generation Sequencing Platform for Detection and Surveillance of Bladder Cancer
This is a prospective, multicenter observational study designed to collect urine and tumor biospecimens and associated clinical data from patients undergoing evaluation, treatment, or surveillance for urothelial carcinoma.
- Conditions
- Bladder Cancer, Urothelial Carcinoma (UC), Hematuria, Upper Tract Urothelial Cancer
- Trial name
- INSITE (NCT07673016)
- Where
- 23 sites in United States, Puerto Rico
- Volunteers
- 2,500 people
- Sponsor
- Convergent Genomics, Inc.
Bladder Cancer, Urothelial Carcinoma
Bladder Cancer Screening Trial
There is currently no accepted screening strategy for patients at high risk of developing bladder cancer. This study will ask patients to complete a urine test every 6 months for 2 years to help assess if routine screening helps…
- Conditions
- Bladder Cancer, Urothelial Carcinoma, Hematuria, Smoking Cessation
- Trial name
- NCT05646485
- Testing
- Urinalysis
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Hematuria, Urination Disorders
Rigid Versus Flexible Cystoscopy in Women
The study will help define the best tolerated approach to cystoscopy in women by randomly comparing flexible to rigid cystoscopy.
- Conditions
- Hematuria, Urination Disorders, Voiding Dysfunction, Recurrent Urinary Tract Infection
- Trial name
- NCT00214045
- Testing
- Flexible Cystoscopy, Rigid Cystoscopy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Macrohematuria
Air vs. Liquid: A Study on Cystoscopy Performance and Visibility Enhancement in Macrohematuria Cases
Macroscopic haematuria is a common urological emergency. Diagnostic cystoscopy is the gold standard for identifying the bleeding source; however, blood and clots within the bladder significantly impair endoscopic visibility when…
- Trial name
- AIROSCOPY (NCT07618221)
- Testing
- Air-based flexible cystoscopy, Saline-based flexible cystoscopy
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Kantonsspital Baden
Bladder Cancer, Hematuria; Benign
PENK Methylation Test for Detecting Bladder Cancer
The primary objective of this clinical trial is to determine the sensitivity and specificity of the EarlyTect® Bladder Cancer test for bladder cancer among patients with hematuria by comparing it to the results of cystoscopy…
- Trial name
- NCT05220189
- Testing
- EarlyTect® Bladder Cancer test
- Where
- South Korea
- Volunteers
- 1,549 people
- Sponsor
- Asan Medical Center
Bladder Cancer
Screening for Bladder Cancer
In the study proposed, up to 1,500 men age 60 and over with strong smoking histories will test their urine for the presence of blood daily for two 10-day testing periods with the Ames Hemastix.
- Trial name
- NCT00848627
- Testing
- Specimen and questionnaires only
- Where
- 3 sites in United States, Canada
- Volunteers
- 197 people
- Sponsor
- Baylor College of Medicine
Hematuria, Bladder Cancer
A Trial of a Modified Cystoscopy Method to Reduce Pain Perception
The goal of this project is to improve patient experience of cystoscopy using a non-pharmacologic modification of procedure. Cystoscopy is a common outpatient procedure for urology patients and is usually performed without…
- Conditions
- Hematuria, Bladder Cancer, Bladder Disease
- Trial name
- NCT03257293
- Testing
- Modified Cystoscopy, Routine Cystoscopy
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- Western University, Canada
Urothelial Carcinoma
Performance Evaluation of a Urine-based Methylation Assay for Urothelial Carcinoma
Urothelial carcinoma (UC) is the most common malignancy of the urinary system. Hematuria is a significant clinical manifestation of UC, often diagnosed through invasive procedures.
- Trial name
- UMT-UC (NCT06912672)
- Testing
- Evaluate the diagnostic performance of EPIPROBE TAGMe DNA Methylation Detection Kit for Urothelial Cancer
- Volunteers
- 1,500 people
- Sponsor
- Shanghai Epiprobe Biotechnology Co., Ltd.
Urothelial Carcinoma
Investigation and Detection of Urological Neoplasia in Patients Referred With Suspected Urinary Tract Cancer:
Bladder cancer is common in the UK and can kill. A common sign of bladder cancer is blood in the urine (haematuria). GPs will refer to a specialist (Urologist) for further investigation of haematuria if they suspect cancer.
- Trial name
- IDENTIFY (NCT03548688)
- Where
- United Kingdom
- Volunteers
- 11,059 people
- Sponsor
- British Urology Researchers in Surgical Training
BPH (Benign Prostatic Hyperplasia), BPH With Symptomatic Lower Urinary Tract Symptoms
Use of PuraStat Following Aquablation to Determine if There is Change in Hematuria & Probability of Same Day Discharge
Randomized, single-blinded investigational study to assess the safety of PuraStat following the Aquablation procedure
- Trial name
- PuraStat (NCT07789041)
- Testing
- PuraStat hydrogel and the syringe
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Endeavor Health
BPH With Urinary Obstruction, BPH
Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP
Holmium Laser Enucleation of the Prostate (HoLEP) is a size-independent treatment option for benign prostatic hypertrophy (BPH) as recommended by the American Urological Association (AUA) Guidelines.
- Conditions
- BPH With Urinary Obstruction, BPH, Hematuria, Same Day Discharge
- Trial name
- NCT05620784
- Testing
- Furosemide
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hematuria
Value of an Integral Color Scale on Urine Collection Bags Versus Use of a Strip in Description of Hematuria.
The investigators hypothesize that incorporation of a colorimetric scale on urine collection bags to estimate degree of hematuria would allow better characterization of urine by healthcare staff thus leading to improved patient…
- Trial name
- HEMAPOCHE (NCT03408288)
- Testing
- Hemapoche, Hemastick, Color description
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Bladder Cancer
Assessment of BladderLight SurvEILlance
Is BladderLight® (BL) urine testing accurate, as a non-invasive method, to exclude presence of bladder cancer in patients.
- Trial name
- ABSEIL (NCT03427034)
- Testing
- BladderLight®
- Volunteers
- 2,100 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Bladder Cancer, Hematuria
Multi Institutional Study in Patient Presenting With Hematuria
The primary objective of this study is to evaluate the performance of the methylation marker panel for the detection of bladder cancer in patients with gross or microscopic hematuria.
- Trial name
- NCT03122964
- Testing
- AssureMDx
- Where
- United States
- Volunteers
- 1,148 people, healthy volunteers welcome
- Sponsor
- MDx Health