Clinical trials: Hemofiltration
Poisoning by Paraquat With Undetermined Intent
Role of CVVH in Patients With Acute Paraquat Poisoning
Paraquat poisoning is characterized by multiple organ failure and pulmonary fibrosis with respiratory failure. Accumulating evidence suggested that continuous venovenous hemofiltration (CVVH) had a beneficial role in the…
- Trial name
- PQ (NCT01709604)
- Testing
- CVVH, Standardized therapy regimens
- Where
- 2 sites in China
- Volunteers
- 110 people
- Sponsor
- Ai Peng
Bone Marrow Transplantation, Respiratory Insufficiency
Hemofiltration for Respiratory Failure After Bone Marrow Transplantation
For children undergoing bone marrow transplantation, respiratory failure is a devastating complication, with mortality expectations well above 60%. The researchers have devised a novel strategy that may greatly improve survival.
- Trial name
- NCT00120575
- Testing
- hemofiltration
- Where
- 7 sites in United States, Canada and 2 more
- Volunteers
- 6 people
- Sponsor
- Stanford University
Critically Ill, Intra-Abdominal Hypertension
The Influence of Fluid Removal Using Continuous Venovenous Hemofiltration (CVVH) on Intra-abdominal Pressure and Kidney Function
Intra- abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are a cause of organ dysfunction in critically ill patients.
- Conditions
- Critically Ill, Intra-Abdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury
- Trial name
- NCT01077895
- Testing
- CVVH, ultrafiltration, ultrafiltration control group
- Where
- 2 sites in Belgium
- Sponsor
- University Hospital, Ghent
Systemic Inflammatory Response Syndrome, Acute Kidney Injury
High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery
A high cut off dialyzer (septeX) is tested in patients after cardio-thoracic surgery with incidence of "systemic inflammatory response syndrome" (SIRS) and associated increased risk for acute kidney injury (AKI).
- Trial name
- HICOSIRS (NCT01579396)
- Testing
- septeX, standard therapy
- Where
- Germany
- Sponsor
- Vantive Health LLC
Acute Kidney Injury
Effect of CVVH on NGAL in Septic AKI
The plasma level of neutrophil gelatinase-associated lipocalin (NGAL) in critically ill patients with AKI is not affected by continuous venovenous hemofiltration (CVVH).
- Trial name
- NCT02536027
- Testing
- continuous venovenous hemofiltration
- Volunteers
- 30 people
- Sponsor
- First People's Hospital of Chenzhou
Acute Pancreatitis
Early High-volume Continuous Veno-venous Hemofiltration for Patients With Severe Acute Pancreatitis
The purpose of this study is to determine the effect and safety of early high-volume continuous veno-venous hemofiltration for patients with severe acute pancreatitis.
- Trial name
- EHVCVVHSAP (NCT01595672)
- Testing
- AN69 hemofilter, conventional treatments
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Air Force Military Medical University, China
Platelet Function
Monitoring Platelet Function During Continuous Hemodialysis
Aim of the study is a description of changes in platelet function during continuous veno-venous hemodialysis or hemofiltration in patients on an intensive care unit using the Multiplate system.
- Trial name
- NCT01837758
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Goethe University
Acute-On-Chronic Liver Failure
Use of HA 330-II for Hemofiltration in Patients With ALF as a Bridge to Liver Transplantation .
ALF (ALF) is defined by three criteria: (1) rapid development of hepatocellular dysfunction (jaundice, coagulopathy), (2) hepatic encephalopathy, and (3) absence of a prior history of liver disease.
- Trial name
- NCT04243655
- Testing
- HA 330-II, Standard medical treatment (SMT)
- Where
- India
- Volunteers
- 10 people
- Sponsor
- Asian Institute of Gastroenterology, India
Sepsis, Need of Cardiac Surgery
International Registry on the Use of the CytoSorb Adsorber
Registry on the use of the CytoSorb® adsorber in ICU patients.
- Trial name
- CytoSorb (NCT02312024)
- Testing
- Use of CytoSorb adsorber
- Where
- 19 sites in Austria, Germany and 1 more
- Volunteers
- 1,434 people
- Sponsor
- Jena University Hospital
Haemofiltration
Clinical Investigation of the Safety of the MediSieve Magnetic Haemofiltration System in Healthy Volunteers
This is a single-centre, non-randomised, prospective study to assess the safety of the MediSieve blood filtration system in healthy volunteers
- Trial name
- NCT05713188
- Testing
- MediSieve Magnetic Haemofiltration System
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- MediSieve Limited
Kidney Injury, Acute
Effects of Continuous Veno-venous Haemofiltration on Plasma Lactate in Critically Ill Patients
Continuous Veno-Venous Hemofiltration (CVVH) can eliminate metabolic products effectively and replace renal function partly. It is widely used in intensive care units (ICUs), especially for patients with acute kidney…
- Trial name
- NCT01824771
- Testing
- Plasma lactate were measured
- Where
- China
- Volunteers
- 15 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Restless Legs Syndrome
Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomatic Restless Legs Syndrome (RLS) Associated With Chronic Kidney Disease (CKD) Managed With Haemodialysis (Including Haemofiltration and Haemodiafiltration)
This is a multicenter, placebo controlled, parallel group, double-blind, randomized comparison study to evaluate the efficacy and safety of ropinirole IR tablets orally administered for 12 weeks in patients with symptomatic…
- Trial name
- NCT00996944
- Testing
- Ropinirole immediate release (IR)
- Where
- 19 sites in Japan
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Renal Failure, Acute
The Efficacity of Hemodiafiltration Versus Hemofiltration for Renal Insufficiency During Intensive Care
The primary objective of this study is to compare the efficacity of hemodiafiltration and hemofiltration for decreasing plasma urea at 12h among intensive care patients.
- Trial name
- NCT01403220
- Testing
- Hemodiafiltration first, Hemofiltration first
- Where
- France
- Volunteers
- 163 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Renal Failure
Fondaparinux as an Anticoagulant in Haemofiltration in Patients With Acute Kidney Failure.
The purpose of this project is to assess the safety and effectiveness of fondaparinux, a new drug to prevent blood clotting in the continuous dialysis machine used in intensive care patients who have kidney failure.
- Trial name
- NCT00256100
- Testing
- Fondaparinux Sodium
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Melbourne Health
CVVH, Filtration Fraction
Built-in Calculator Optimizes Continuous Veno-venous Hemofiltration Prescription and Improves Therapeutic Quality in Critically-ill Acute Kidney Injury Patients
The goal of this observational study is to compare in ICU patients received CVVH treatment. The main questions it aims to answer are: Control of Filtration fraction by built-in calculator Reduced filter clotting and prolong…
- Conditions
- CVVH, Filtration Fraction, Built-in Culculator
- Trial name
- NCT05638711
- Testing
- Built-in calculator to calculate Filtration fraction
- Where
- Taiwan
- Volunteers
- 1 people
- Sponsor
- Taipei Medical University
Inflammation
Effects of Hemofiltration and Mannitol Treatment on Cardiopulmonary-Bypass Induced Immunosuppression
After cardiac surgery with cardiopulmonar bypass, the LPS-stimulated cytokine response has been previously shown to be depressed.
- Trial name
- NCT00426192
- Testing
- i.v. mannitol, hemofiltration
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- University Hospital, Saarland
Acute Kidney Injury
Citrate Versus Heparin Anticoagulation in Continuous Venovenous Hemofiltration
The purpose of this study is to compare citrate regional anticoagulation with systemic heparinization in continuous venovenous hemofiltration.
- Trial name
- CASH-CVVH (NCT00209378)
- Testing
- regional anticoagulation with citrate, HfCitPre
- Where
- 9 sites in Netherlands
- Volunteers
- 139 people
- Sponsor
- Universitair Ziekenhuis Brussel
Hemofiltration, Nurse Training
Simulation for Continuous Veno-venous Hemofiltration in Intensive caRe
Continuous Veno-Veinous Hemofiltration (CVVH) is a frequently used renal replacement therapy in intensive care units for patients with acute renal failure. In theory, this therapy should be continuous, 24 hours/day.
- Conditions
- Hemofiltration, Nurse Training, Health Care Provider Education
- Trial name
- SIMHeR (NCT02379234)
- Testing
- simulation
- Where
- France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Angers
Acute Kidney Injury, Continuous Venovenous Hemofiltration
Bionenergetic Balance During CVVH
The bioenergetic balance is the sum of energy exchanged during CRRT and is mostly defined by citrate glucose and lactate. When CRRT was performed with the older dialysis fluids, glucose and lactate could be an important source of…
- Conditions
- Acute Kidney Injury, Continuous Venovenous Hemofiltration, Energy Metabolism, Resting Energy Expenditure
- Trial name
- BALANCE (NCT06483542)
- Testing
- bioenergetic balance
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Hypernatremia, Critically Ill
Continuous Venovenous Hemofiltration Versus Conventional Treatment for Acute Severe Hypernatremia
The patients with severe hypernatremia who received conventional treatment are often undertreated. Continuous venovenous hemofiltration (CVVH) can effectively remove solute or water from circulation system.
- Trial name
- NCT02449382
- Testing
- continuous venovenous hemofiltration, Control group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Air Force Military Medical University, China