Clinical trials: Hemorrhage Postoperative
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Post Operative Pain, Post-Op Hemorrhage
Admission of the Patient to the Clinic After Surgery
Aim:This research was designed as a randomized controlled study to examine the effect of the game-based virtual reality learning method on the patient's post-operative admission to the clinic on the learning outcomes of the…
- Conditions
- Post Operative Pain, Post-Op Hemorrhage, Postoperative Hypothermia, Nurse's Role
- Trial name
- NCT05469399
- Testing
- Experimental Group, Control Group
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Gazi University
Postpartum Hemorrhage
Comparison Between Rectal & Sublingual Misoprostol Before Caesarian Section To Reduce Intra & Post-Operative Blood Loss
The aim of the work is to evaluate \& compare the effectiveness of rectally administered PGE1 synthetic analogue (misoprostol) 400 microgram versus sublingually administered misoprostol before caesarean section to decrease blood…
- Trial name
- NCT02083107
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative, Postoperative Hemorrhage
Effect of Bupivacaine-infused Fibrin Sealant Application on Post-tonsillectomy Pain & Hemorrhage
The purpose of this study is to evaluate the effect of combining two interventions already in use at some institutions for reducing post-operative pain following tonsillectomy or adenotonsillectomy.
- Trial name
- NCT02343263
- Testing
- Bupivacaine, Fibrin Sealant
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Indiana University
Blood Loss, Surgical, Blood Loss, Postoperative
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate, Pre-operative Administration.
- Trial name
- NCT04656067
- Testing
- Oxytocin ,Tranexamic acid and Ethamsylate
- Where
- Egypt
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Knee Prosthesis
Effect of Normothermia Care Bundle in Knee Replacement Surgery
Osteoarthritis is a disease characterized by disruption of the integrity of articular cartilage as a result of erosion of articular cartilage.
- Trial name
- NCT06454877
- Testing
- active heating, pasive heating
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Direct Oral Anticoagulants (DOACs), Oral Surgical Procedures
Oral Biopsy Bleeding in Patients on Direct Oral Anticoagulants (DOACs)
Direct oral anticoagulants (DOACs) are increasingly used, but evidence on bleeding risk during oral soft tissue biopsy is limited.
- Trial name
- DOACS_BX (NCT07520890)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Gastric Bypass, Obesity
Oversewing Staple Line of The Gastric Remnant
Background: Roux-en-Y gastric bypass (RYGB) is a surgery with low rate complications. However, it is not exempt from them, and 1-6% suffer complications such as postoperative bleeding.
- Trial name
- NCT04884230
- Testing
- Oversewing
- Where
- Venezuela
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Unidad Internacional de Cirugia Bariatrica y Metabolica
Infection
Preoperative Dose of Co-amoxiclav for Prevention of Postoperative Complications in Dentoalveolar Surgery
There was no evidence to judge the effects of preventative antibiotics for extractions of severely decayed teeth, teeth in diseased gums, or extractions in patients who are sick or have low immunity to infection.
- Trial name
- NCT03844776
- Testing
- Co-Amoxiclav, Paracetamol, Chlorhexidine mouthwash
- Where
- Saudi Arabia
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Taibah University
Hematoma, Postoperative Bleeding
Analysis of Hematoma Following Breast Surgery
A retrospective review of patients who developed hematoma following breast surgery from 2003 to 2018 in a single institution was performed.
- Trial name
- NCT03515525
- Testing
- Closed-suction drain fluid volume
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Hypothermia, Hemorrhage, Postpartum
Complications Associated With Intraoperative Hypothermia.
Maintaining intraoperative normothermia and temperature measurement is a marker of quality of care. We know that intraoperative hypothermia is associated with an increased risk of cardiovascular events, infection of the surgical…
- Conditions
- Hypothermia, Hemorrhage, Postpartum, Infection Surgical Wound, Transfusion-dependent Anemia
- Trial name
- NCT05203016
- Testing
- Hipotermia/Normotermia
- Where
- Spain
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Blood Loss, Surgical
Efficacy of Tranexamic Acid in Preventing Post Operative Blood Loss in Bone Sarcoma Patient
investigator will see the efficacy of tranexamic acid in limb salvage surgery patients which will prevent blood loss and help in conservation of blood products.
- Trial name
- NCT05427513
- Testing
- Tranexamic acid injection, normal saline
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Knee Osteoarthritis, Blood Loss
Extended Postoperative Oral Tranexamic Acid in Knee Replacement
A comparison of outcomes between use of oral tranexamic acid as compared to oral placebo in the first days after total knee replacement will be made to determine impact on clinical indications and patient reported outcomes.
- Conditions
- Knee Osteoarthritis, Blood Loss, Pain, Postoperative
- Trial name
- NCT05099276
- Testing
- Tranexamic Acid Pill
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Campbell Clinic
Postoperative Bleeding
Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee Arthroplasty
Tranexamic acid (TXA) is an anti-fibrinolytic agent developed in the 1960s that has been safely used to reduce blood loss, transfusion rates and bleeding-associated mortality in trauma, obstetrics and orthopedic surgery…
- Trial name
- TXA (NCT06208267)
- Testing
- Tranexamic acid
- Where
- Canada
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- St. Mary's Research Center, Canada
Blood Platelet Disorders, Cardiac Surgery
Observational Study of Platelet Dysfunction Assessed by Thromboelastography in Cardiovascular Surgery (DISPLATEG)
Perioperative bleeding requiring blood transfusion is common during cardiovascular surgery, especially in procedures requiring cardiopulmonary bypass. Adenosine diphosphate (ADP) plays a fundamental role in platelet function.
- Conditions
- Blood Platelet Disorders, Cardiac Surgery, Postoperative Bleeding
- Trial name
- DISPLATEG (NCT06961175)
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Blood Loss, Surgical, Postoperative Hemorrhage
Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.
The goal of this clinical trial is to learn whether the Hemorai Vysio wearable device can be used safely and feasibly to track relative changes over time in tissue oxygen, hemoglobin-related signals, blood flow, and oxygen use…
- Trial name
- VYSIO-FEASIBIL (NCT07826637)
- Testing
- Wearable optical hemodynamic monitoring device
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hemorai Inc
Thrombosis
Efficacy and Safety of Short-term Postoperative Anticoagulant Therapy to Prevente Thrombosis in Arterovenous Fistula
Many guidelines at home and abroad advocate that arteriovenous fistula should be the first choice of permanent vascular access, but it is easy to form thrombus in a short time after arteriovenous fistula molding, resulting in…
- Trial name
- EASOAT (NCT04164693)
- Testing
- Low molecular weight heparin, non anticoagulant therapy group
- Where
- China
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
The Role of Valsalva Manoeuvre, in Thyroidectomy to Reduce Postoperative Bleeding
Valsalva Maneuver in Thyroidectomy
Bleeding after total thyroidectomy remains a rare event that affects early postoperative morbidity, occurring in 0.3% up to 4.2% of cases.
- Trial name
- NCT05474261
- Testing
- Valsalva maneuver
- Where
- Italy
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Post-Op Complication
A Randomized Trial of Lenient Versus Strict Arm Instruction Post Cardiac Device Surgery
The purpose and objectives of this study is to investigate whether reducing the existing arm restrictions on patients who receive Cardiac Implantable Electronic Devices (CIED) will result in an improved patient experience post…
- Trial name
- LENIENT (NCT04915261)
- Testing
- Lenient Arm Restriction, Strict Arm Restriction
- Where
- Canada
- Volunteers
- 6,300 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Hemorrhage, Pain
Effect of Tonsillar Pillar Closure on Postoperative Pain and Bleeding Risk After Tonsillectomy
The purpose of this study is to determine if closing the tonsil fossa after tonsillectomy leads to less pain and bleeding risk than leaving it open to heal by secondary intention.
- Trial name
- NCT00394849
- Testing
- suture one tonsillar fossa
- Where
- United States
- Volunteers
- 763 people, healthy volunteers welcome
- Sponsor
- Indiana University