Clinical trials: Herniation, Disc
Disc Herniation
Silent Lumbar Disc Herniation Syndrome
LDH is a common phenomenon that is often described in association with various pathological processes affecting the neuromuscular and locomotor systems.
- Trial name
- NCT06453499
- Testing
- Physical therapy
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Noha Khaled Shoukry
Lumbar Disc Herniation
A Biomechanical Study of the Lumbar Intervertebral Disc by Lever Positioning Manipulation
Purpose of Study: The purpose of this clinical trial is the clinical efficacy of different trigger modes of lever positioning manipulation (LPM) for the treatment of lumbar disc herniation (LDH).
- Trial name
- NCT06872918
- Testing
- Lever positioning manipulation, Cluster of pseudo-manipulators, Mechanics and kinematics data acquisition of unilateral wrenching patterns in lever positioning manipulation
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Lumbar Disc Herniation, Pain, Postoperative
mTLIP vs. ITP Blocks in Lumbar Disc Surgery
to compare ultrasonography (USG)-guided intertransverse process block and modified thoracolumbar interfascial plan (mTLIP) block in the treatment of postoperative pain in patients undergoing lumbar disc herniation surgery under…
- Conditions
- Lumbar Disc Herniation, Pain, Postoperative, Regional Aneshesia
- Trial name
- NCT06391541
- Testing
- modified thoracolumbar interfacial plan block (mTLIP), Intertransverse process block (ITP)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Low Back Pain
Serum Cytokine Levels in Patients with Lumbal Disc Herniation and Effectiveness of Exercise
The aim of the study is to investigate serum cytokine levels and the efficacy of lumbar stabilization exercises in patients with lumbar disc herniation with and without neurological deficits.
- Trial name
- NCT04912388
- Testing
- Lumbal stabilization excercises, Conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Lumbar Radiculopathy, Lumbar Herniated Disk
Does Intraoperative Application of Steroids Affect Early Outcomes in Patients Undergoing Endoscopic Lumbar Discectomy?
Prospective randomised trial assessing whether intraoperative application of steroids leads to better clinical outcomes in patients submitted to lumbar discectomy
- Trial name
- NCT07411326
- Testing
- Intervention Group, Control group (Normal Saline) (C)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Radiculopathy
Presentation of Lumbar Disc and Reduction of Symptoms
The trial aims to assess the hypothesis that presentation of the disc material to the patient following a lumbar microdiscectomy would positively influence the improvement in their leg and back symptoms.
- Trial name
- POLDAROS (NCT00440856)
- Testing
- Presentation of excised intervertebral disc fragments
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Interleukines
Study of Cytokines Serum Levels in Chronic Low Back Pain
The purpose of this study is to: evaluate if there is an association between elevated levels of cytokines and chronic pain due to herniated disk disease measured cytokines levels in chronic low back pain and in healthy subjects.
- Trial name
- cytokine (NCT00991042)
- Testing
- blood collect
- Where
- Brazil
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Postoperative Pain
Efficiency of Thoracolumbar Interfascial Plane Block in Lumbar Disk Surgery
Objectives:Lomber disc hernia is one of the most common diseases in Turkey. The prevalence in various studies is between 60-80% and incidence is between 1-3% for the entire population,Goal of TLIP is to provide a same impact in…
- Trial name
- NCT03180099
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Erzurum Palandöken State Hospital
Lumbar Disc Herniation
Remission of Lumbar Disc Herniation by Physiotherapy
This study was conducted with the aim of determining whether or not Non surgical spinal decompression therapy was effective in remission of herniation, decreasing pain and improving functional status.
- Trial name
- NCT02699164
- Testing
- DRX 9000, Axiom Worldwide, Tampa, Florida, physiotherapy, spinal stabilization exercise
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Intervertebral Disc Displacement, Intervertebral Disc Degeneration
Lumbar Disc Space Height in Young Disc Herniation and Degeneration Patients
As low back pain (LBP) imposes a heavy socioeconomic burden, early detection of pathologic intervertebral disc change in young adults holds high clinical relevance as a common structural cause of LBP.
- Conditions
- Intervertebral Disc Displacement, Intervertebral Disc Degeneration, Low Back Pain
- Trial name
- NCT02351206
- Testing
- x-ray, MRI
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Jaseng Hospital of Korean Medicine
Lumbar Spine Surgery, Lumbar Disc Herniation
The Effect of Mobilization Protocol Assisted With Simulated Clinical Immersion Videos on Patients Undergoing Lumbar Spine Surgery
This study focused on examining the effect of mobilization protocol assisted with simulated clinical immersion videos on postoperative pain, fear of movement, mobility level and satisfaction in patients undergoing lumbar spine…
- Trial name
- NCT05462210
- Testing
- Mobilization Protocol Assisted with Simulated Clinical Immersion Videos
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Intervertebral Disc Herniation
MR Elastography for the Herniated Intervertebral Disc
Low back pain is a major cause of disability, especially in the working-age population. A total of 149 million working days are lost every year as a consequence of back pain.
- Trial name
- NCT03340545
- Testing
- Custom Magnetic Resonance Elastography Device
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Penn State University
Lumbar Disc Herniation
Impact of Transforaminal Epidural Steroid Injection in Lumbar Disc Prolpse on Micro RNA-155 Serum Level
Chronic pain could be considered a brain disease as it can affect multiple aspects of brain function, chemistry, neural networks and structure. Pain is associated with impaired cognitive function (1).
- Trial name
- NCT05626283
- Testing
- transforaminal epidural injection., micro RNA-155 serum level
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Degenerative Disc Disease, Degenerative Spondylolisthesis
The Five-repetition Sit-to-stand Test for Lower Back Pain or Radiculopathy
The five-repetition sit-to-stand test (5R-STS) has been used in many medical disciplines, but has never been correlated with or validated in regard to degenerative spinal diseases.
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Herniated Disc, Stenosis, Spinal
- Trial name
- 5R-STS (NCT03303300)
- Where
- Netherlands
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Marc Schröder
Intervertebral Disc Displacement, Lumbar Disc Herniation
The Effect of Manual Therapy on Psychological Factors and Quality of Life in Lumbal Disc Herniation Patients
When the literature is examined, there are studies examining the relationship between low back pain and anxiety depression, quality of life and LDH in patients with lumbar disc herniation.
- Conditions
- Intervertebral Disc Displacement, Lumbar Disc Herniation, Psychological, Quality of Life
- Trial name
- NCT05804357
- Testing
- Manual Therapy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Lumbar Disc Herniation
Brain Connectomic Mechanisms of Spinal Manipulative Therapy on LDH Analgesia Based on Multimodal MRI
Low back and leg pain caused by lumbar disc herniation (LDH) is common. Lever positioning manipulation (LPM) is a spinal manual therapy used to relieve this pain, but how it affects the brain is unclear.
- Trial name
- NCT07728149
- Testing
- Active Lever Positioning Manipulation
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Disk Herniated Lumbar
Muscle Analyze In Patient With Disc Herniation
This study which was planned to investigate the factors affecting m. erector spinae (ES), m. multifidus (MF), m. psoas major (PM) and m. quadratus lumborum (QL), which stabilize the lumbar region in the case of disc herniation.
- Trial name
- NCT05245214
- Testing
- Magnetic Resonance Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Disc Herniation
The Effect of White Noise in Patients Undergoing Lumbar Disc Herniation Surgery
The aim of this clinical trial is to determine the effectiveness of listening to white noise on the sleep quality, comfort level, satisfaction level of patients after lumbar disc herniation surgery.
- Trial name
- NCT05687305
- Testing
- White Noise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi