Clinical trials: Herniation, Disc
Lumbar Disc Herniation
Perioperative Outcome of Corticosteroids in Transforaminal Endoscopic Lumbar Discectomy
The endoscopic discectomy has rapidly developed and increased need by patients. This procedure is widely performed by interventional pain physicians as well as by spine surgeons because it requires no general anesthesia or…
- Trial name
- NCT03273036
- Testing
- 40 mg Triamcinolone acetate 1 cc
- Volunteers
- 30 people
- Sponsor
- Ramathibodi Hospital
Lumbar Disc Herniation
The Efficacy of Clinical Pilates Exercises on Individuals With Lumbar Disc Herniation
The aim of the study is to determine the effects of clinical Pilates Exercises on the level of pain, functional status, flexibility, static and dynamic endurance of the truncus muscles and quality of life in patients with lumbar…
- Trial name
- NCT03198273
- Testing
- Clinical pilates exercises, physiotherapy program
- Where
- Cyprus
- Volunteers
- 88 people
- Sponsor
- Eastern Mediterranean University
Lumbar Spine Disc Herniation
Targeted Disc Decompression (TDD) for Contained Herniated Lumbar Discs
The prospective Clinical Series (CS) aims to prove the hypothesis that Targeted Disc Decompression (TDD) reduces the pain in patients suffering from radicular leg pain secondary to a contained focal disc protrusion…
- Trial name
- TDD (NCT01429363)
- Testing
- Targeted disc decompression
- Where
- 3 sites in Netherlands
- Volunteers
- 9 people
- Sponsor
- Rijnstate Hospital
Acute Sciatica, Lumbar Disc Herniation
Chiropractic Spinal Manipulative Therapy for Acute Sciatica Secondary to Lumbar Disc Herniation
Comparisons of surgical and non-operative treatment of patients with acute sciatica secondary to lumbar intervertebral disc herniation (AS/LDH) have shown no appreciable difference in outcome.
- Trial name
- NCT01552486
- Testing
- Chiropractic Spinal Manipulative Therapy, Usual Care
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Vancouver General Hospital
Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation
Multicentric Registry for the Detection of C5 Palsy After Anterior Cervical Discectomy and Fusion
Detect the reason for the frequently occurring C5 palsy after anterior cervical discectomy and fusion
- Conditions
- Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation, Suspected Cervical Spine Instability
- Trial name
- C5registry (NCT02875431)
- Testing
- Patients undergo ACDF or cervical vertebral body replacement
- Where
- Germany
- Volunteers
- 1,087 people
- Sponsor
- Technical University of Munich
Lumbar Disc Herniation
Remission of Lumbar Disc Herniation by Physiotherapy
This study was conducted with the aim of determining whether or not Non surgical spinal decompression therapy was effective in remission of herniation, decreasing pain and improving functional status.
- Trial name
- NCT02699164
- Testing
- DRX 9000, Axiom Worldwide, Tampa, Florida, physiotherapy, spinal stabilization exercise
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Long-term Outcomes of Surgical and Nonsurgical Management of Sciatica Secondary to a Lumbar Disc Herniation or Spinal Stenosis
The rate of success 12 months after surgery is reported to be 60-65% in patients with lumbar disc herniation and 60-70% in patients with spinal stenosis.
- Trial name
- NCT02836730
- Testing
- Low back pain surgery
- Where
- Denmark
- Volunteers
- 425 people
- Sponsor
- Back and Rehabilitation Center, Copenhagen
Lumbar Disc Herniation
A Trial of Percutaneous Lumbar Discectomy Combined With Ozone for Treatment of LDH
Lumbar disc herniation (LDH) is a common pathological process leading to spinal surgery. Open discectomy used to be a widespread procedure for surgical treatment for symptomatic LDH.
- Trial name
- NCT02372032
- Testing
- percutaneous lumbar discectomy, ozone therapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Zhongda Hospital
Lumbar Disc Herniation
Comparison of Different Treatment Methods in Lumbal Disc Herniation Treatment
The aim of this study is to determine the effectiveness of three different treatment methods which consists spinal decompression, deep friction massage and exercise.
- Trial name
- NCT02572622
- Testing
- non -surgical spinal decompression therapy, deep friction massage,, electrotherapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Degenerative Disc Disease, Lumbar, Disc Herniation, Lumbar
Satellite™ PEEK Nucleus Replacement Retrospective Analysis
The Satellite™ Retrospective Analysis is an international, retrospective, multi-center, non-interventional post-marketing study designed to document and analyze existing data with the device in a "real-world" setting.
- Trial name
- NCT01110967
- Where
- 3 sites in Czechia, Slovakia and 1 more
- Volunteers
- 40 people
- Sponsor
- Medtronic Spinal and Biologics
Symptomatic Lumbar Disc Herniation, Symptomatic Grade I Lumbar Spondylolisthesis
Neurosurgery Patient Outcomes in Treating Spinal Disorders
The creation of a multi-center cooperative research group encompassing academic and community-based spinal practices . . .
- Trial name
- Neuropoint SD (NCT01220921)
- Testing
- Lumbar Discectomy, Single-level lumbar fusion
- Where
- 13 sites in United States, Canada
- Volunteers
- 198 people
- Sponsor
- Greenwich Hospital
Lumbar Disc Herniation
Microendoscopic Discectomy Vs Transforaminal Endoscopic Lumbar Discectomy Vs Open Discectomy
In our study, a multicenter randomized controlled，single blind trial will be performed to evaluate the effectiveness and safety of these three procedures for the treatment of symptomatic lumbar disc herniation.
- Trial name
- NCT02358291
- Testing
- open discectomy, microendoscopic discectomy, transforaminal endoscopic lumbar discectomy
- Volunteers
- 240 people
- Sponsor
- Southeast University, China
Lumbar Disc Herniation
Lumbar Intervertebral Disc Herniation
The purpose of this study is to compare safety and outcomes of the following treatments of lumbar disc herniation: (1) discectomy with posterior dynamic stabilization with those of (2) discectomy alone or (3) discectomy with…
- Trial name
- LIDH (NCT02110186)
- Testing
- Dynamic Stabilization, Discectomy, Instrumentation and fusion
- Where
- China
- Volunteers
- 195 people
- Sponsor
- Third Military Medical University
Lumbar Disc Herniation
Short Versus Long Post-Operative Restrictions Following Lumbar Discectomy
Post-operative restrictions following lumbar discectomy is a controversial topic. While the most widely accepted protocol restricts bending, lifting, and twisting for four to six weeks following discectomy, a number of studies…
- Trial name
- NCT01363830
- Testing
- Two-Week Post-Operative Restriction, Six-Week Post-Operative Restriction
- Where
- 3 sites in United States
- Volunteers
- 420 people
- Sponsor
- Brigham and Women's Hospital
Lumbar Spine Disc Herniation
Effects of Addition of Magnesium Sulfate in Spinal Anesthesia on Sensory-Motor Blocks and Postoperative Pain in Lumbar Disk Herniation Surgery
The purpose of this study is to Compare three methods of intrathecal bupivacaine; bupivacaine-fentanyl; bupivacaine-fentanyl-magnesium sulfate on sensory-motor blocks and postoperative pain in patients undergoing lumbar disk…
- Trial name
- NCT01843296
- Testing
- Magnesium Sulfate, Spinal Anesthesia, Bupivacaine
- Where
- Iran
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Lumbar Disc Herniation
Wallis Interspinous Dynamic Stability System for Lumbar Disc Herniation: a Prospective Study
Lumbar disc herniation is usually treated by discectomy alone. Nonfusion system such as Wallis interspinous implants have also been successfully used in disc degenerative diseases.
- Trial name
- NCT01824108
- Testing
- Lumbar discectomy, Lumbar discectomy combined with Wallis interspinous dynamic stability system
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Guangdong Provincial People's Hospital
Contained Cervical Disc Herniation
Is Treatment of the Intervertebral Disc More Effective at Short-term Than the Nerve Root in Patients With a Neck Hernia?
Pain management in a neck hernia relies initially on rest, physiotherapy, and/or oral medications. Once these treatments have failed, different alternative procedures can be applied to relief pain.
- Trial name
- NCT01797172
- Testing
- Percutaneous Cervical Nucleoplasty, Pulsed Radio Frequency
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Willy Halim
Degenerative Spinal Stenosis, Disk Herniation
Clinical Trial to Evaluate Safety and Efficacy of Hyalospine® in Lumbar Laminectomy or Laminotomy
The aim of this Phase II trial is to evaluate safety and efficacy of Hyalospine in patients undergoing lumbar laminectomy or laminotomy for degenerative spinal stenosis or disk herniation.
- Trial name
- Hyalospine (NCT00939406)
- Testing
- Hyalospine
- Where
- 3 sites in Germany, Netherlands and 1 more
- Volunteers
- 45 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Lumbar Disc Herniation, Radiculopathy
Rehabilitation Following Lumbar Disc Surgery
The proposed study will be a randomized clinical trial designed to determine the most effective physical therapy program for individuals who have undergone lumbar discectomy surgery.
- Trial name
- NCT00894972
- Testing
- Rehabilitation following lumbar disc surgery (discectomy)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Lumbar Spine Disc Herniation
Lumbar Segmental Stabilization and TENS in Lumbar Disc Herniation
The purpose of this study was to compare the efficacy of method Lumbar Segmental Stabilization and transcutaneous electrical nerve stimulation (TENS) on pain, functional disability and ability to activate the transversus…
- Trial name
- NCT01640431
- Testing
- Lumbar stabilization exercises
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital