Clinical trials: Hiatus Hernia
Congenital Diaphragmatic Hernia, Congenital Diaphragmatic Eventration
Genetic Analysis of Congenital Diaphragmatic Disorders
The purpose of this study is to understand the genetic causes of congenital diaphragmatic disorders (CDD), namely congenital diaphragmatic hernia (CDH), eventration and hiatal hernia. Specifically, the investigators plan to: 1.
- Conditions
- Congenital Diaphragmatic Hernia, Congenital Diaphragmatic Eventration, Congenital Hiatal Hernia, Congenital Diaphragmatic Disorders
- Trial name
- NCT01243229
- Where
- 2 sites in United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University of Utah
Predictive Validity of VLaHHS
Development and Validation of Virtual Laparoscopic Hiatal Hernia Simulator
Part 3 Phase III of this protocol is the interventional portion and is the reason why only this Part is registered and reported within this record.
- Trial name
- (VLaHHS) (NCT06974383)
- Testing
- Training with Virtual Laparoscopic Hiatal Hernia Simulator (VLaHHS)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hiatal Hernia
Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia
This is a prospective randomized, double-blinded, controlled trial that will target enrollment of 46 subjects undergoing laparoscopic hiatal hernia repair surgery.
- Trial name
- NCT05953428
- Testing
- Opioid Sparing Anesthesia Protocol (OSA), Opioid Based Anesthesia Protocol (OBA)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Gastroesophageal Hernia
Hill-grade Knowledge Via Integrated Neural-network for Gastroscopy
The Hill classification, also known as the Hill grade, is a system used to classify the severity of gastroesophageal valve incompetence, specifically related to gastroesophageal reflux disease (GERD) and hiatal hernia.
- Trial name
- HillKING (NCT06040723)
- Testing
- EndoMind
- Where
- Germany
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Hiatal Hernia
Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair
The aim of this study is to find out if using a certain kind of mesh can reduce the chances of hiatal hernias coming back after anti-reflux surgery.
- Trial name
- NCT06444347
- Testing
- Biosynthetic Mesh, Hiatal Hernia Repair
- Where
- 6 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Hernia, Paraesophageal
Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo
We aim to study the impact of perioperative IV lidocaine on postoperative pain control in patients undergoing paraesophageal hernia repair. This is in the context of an established ERAS protocol.
- Trial name
- PEH (NCT04096170)
- Testing
- IV lidocaine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Paraesophageal Hernia
Fundoplication in Laparoscopic PEH Repair Based on FLIP
Prospective randomized controlled trial to identify a sub-set of patients that do not benefit from the routine addition, and added morbidity, of a fundoplication during laparoscopic paraesophageal hernia repair.
- Trial name
- PEHFLIP (NCT05807763)
- Testing
- Laparoscopic paraesophageal hernia repair without fundoplication
- Where
- 2 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- The Foundation for Surgical Innovation and Education
Hiatal Hernia
Biologic Versus Synthetic Mesh for Treatment of Paraesophageal Hernia
The investigators propose a randomized, single blinded controlled trial to compare the use of synthetic versus biologic mesh in hiatal hernia repair, two currently accepted standard of care surgical modalities.
- Trial name
- NCT02242526
- Testing
- Parietex™ Composite Hiatal Mesh, North Haven, CT, Biodesign™ Surgisis® Graft, Cook Medical, Bloomington
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Stony Brook University