Clinical trials: High Caries Risk Patients
Caries
Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste
Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica', the famous 'Toothbrush Tree' used for centuries.
- Trial name
- NCT05109299
- Testing
- Miswak toothpaste, Fluoride toothpaste
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Prevention of Dental Caries
The Influence of Preventive Regimens Containing Different Toothpastes on Caries Risk of High Risk Patients: A Randomized Clinical Trial
66 Participants will be divided into three groups according to the tested regimen (A), where (A1) represents participants will be exposed to regimen including dual zinc plus arginine based toothpaste (Colgate total), (A2)…
- Trial name
- NCT04032210
- Testing
- dual Zinc plus Arginine based toothpaste (Colgate total), Zinc based toothpaste (Crest complete), Fluoride based toothpaste (Signal)
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Risk Reduction
Improving Caries Risk Using Propolis-containing Versus Fluoride-containing Toothpastes in High Caries Risk Patients
This study will be conducted to evaluate the effect of Propolis-containing toothpaste in comparison to Fluoride-containing Toothpaste by caries risk assessment in high caries risk patients.
- Trial name
- NCT03222960
- Testing
- propolis-containing toothpaste, Fluoride-containing toothpaste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
High Caries Risk Patients
Assessment of Inhibition of Biofilm Formation and Plaque Bacterial Count of Fluoride Varnish Containing Chlorhexidine and Cetylpyridinium Chloride Versus Conventional Fluoride Varnish
Two different Fluoride varnish systems(Fluoride varnish containing Chlorhexidine and Cetylpyridinium Chloride (CPC) and conventional fluoride) will be applied to high caries risk patients to assess their clinical effects on…
- Trial name
- NCT04254835
- Testing
- Cervitec F, Ivoclar Vivadent - Schaan Liechtenstein, Fluor Protector, Ivoclar Vivadent - Schaan Liechtenstein
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
High Caries Risk Patients, Caries
Caries Prevention and Side Effects of Gum Arabic and Licorice Extracts Versus Chlorhexidine in High Caries Risk Patients
This trial is to test the caries prevention effect of Arabic gum and Licorice root extracts compared to Chlorhexidine in high caries risk patients.
- Conditions
- High Caries Risk Patients, Caries, Antimicrobial Effect, Side Effect
- Trial name
- NCT03684993
- Testing
- Arabic, Gum, Licorice Root, Chlorhexidine
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class I Cavities in High Caries Risk
Clinical Evaluation of Glass Ionomer With Glass Hybrid Technology Versus Conventional High Viscosity Glass Ionomer in Class I Cavities of High Caries Risk Patients
PICOTS: P: High Caries Risk Patients with bilateral class I cavities. I: Glass Ionomer with Glass Hybrid Technology. C: Conventional High Viscosity Glass Ionomer.
- Trial name
- NCT02856932
- Testing
- Conventional high viscosity glass ionomer, Glass ionomer with glass hybrid technology
- Where
- Egypt
- Volunteers
- 31 people
- Sponsor
- Cairo University
Streptococcus Mutans, High Caries Risk Patients
Streptococcus Mutans Cariogenicity by Real-time PCR in High Caries Risk Patients
In patients with high caries risk, will the use of cinnamon extract or chlorohexidine based mouthwashes have an effect on the percentage of recovery and cariogenicity of Streptococcus mutans (SM) detected by real-time Polymerase…
- Trial name
- NCT04566120
- Testing
- cinnamon extract mouthwash, chlorohexidine based mouthwash
- Where
- Egypt
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Cairo University
Salivary pH
Effect of Matcha Tea Versus Green Tea on Salivary pH and Flow Rate in High Caries Risk Patients
Objectives: To evaluate the effect of green tea versus matcha tea on the salivary pH in high caries risk patients. Materials and methods: Total number of high caries risk patients were randomized into two equal groups (n=).
- Trial name
- NCT06504706
- Testing
- Matcha Tea, Green Tea
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries,Dental, Caries Active
Anticariogenic Properties of Zamzam Water
The present study aims to evaluate and compare the effect of Zamzam water as mouthwashes in high caries-risk patients regarding: i. Streptococcus mutans (S. mutans) count. ii. Oral pH. After 3 and 6 months interval.
- Trial name
- NCT06538532
- Testing
- Zamzam water
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Evaluation of Preventive Regimens With Different Toothpastes vs Fluoride Varnish & Toothpaste in High Caries Patients
This study will be conducted in order to determine the prevention effect of caries preventive regimen using herbal toothpaste and regimen using fluoride toothpaste versus fluoride toothpaste and fluoride varnish on the caries…
- Trial name
- NCT04436913
- Testing
- Himalaya complete care toothpaste, Signal toothpaste, Signal toothpaste and fluoride varnish
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class V Dental Caries, High Caries Risk Patients
Clinical Evaluation of Different Bioactive Restorative Materials for Cervical Carious in High Caries Risk Patients
The aim of the study is to clinically evaluate three different bioactive restorative material in cervical carious lesion in high caries risk patients. Reducing the incidence of recurrent caries is the primary outcome
- Trial name
- NCT06736964
- Testing
- Giomer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
High Caries Risk Patients
Clinical Evaluation of Bioactive Resin Composites Versus Caries Control Technique in Management of Class I Carious Cavities in High Caries Risk Patients: a Randomized Clinical Trial
The aim of the study is to clinically evaluate the performance of S-PRG based \& Alkasite based resin composite restorations versus conventional resin composite restorations after caries control in Class I carious cavities in…
- Trial name
- NCT06797843
- Testing
- "SPRG-based" Resin Composite : (BEAUTIFIL II, Shofu Inc. Kyoto, Japan)., Alkasite based restoration : Cention N, provisional Resin modified glass ionomer followed by Nanohybrid composite
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries; Initial, Pit and Fissure Caries
Retention Rate of Self-etch Resin Based Sealant With and Without Prior Sandblasting
The aim of the study is to clinically assess the effect of sandblasting prior to self-etch resin based sealant on its retention after one year follow up.
- Trial name
- NCT04929327
- Testing
- Self etch Pit and fissure sealant application (prevent seal), Self etch Pit and fissure sealant application (prevent seal) with prior sandblasting, Total etch resin based sealant ultraseal xt
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Streptococcus Mutans
Streptococcus Mutans Pathogenicity by Real-time Polymerase Chain Reaction (PCR) in High Caries Risk Patients
In patients with high caries risk, will the use of sage extract or chlorohexidine based mouthwashes have an effect on the percentage recovery of Streptococcus Mutans (SM) and its pathogenicity detected by Real-Time Polymerase…
- Trial name
- NCT04565912
- Testing
- Sage extract mouthwash, Chlorohexidine based mouthwash
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Preventive Regimens With Herbal and Fluoride Toothpaste on Remineralization in High Caries Patients With Initial Lesions
This study will be conducted to assess the effect of different preventive regimens using herbal toothpaste versus fluoride toothpaste on the management of remineralization and caries risk in high caries risk patients.
- Trial name
- NCT04446390
- Testing
- Himalaya complete care toothpaste, colgate cavity protection
- Where
- 2 sites in Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
High Caries Risk Patients
Clinical Evaluation of Chemically Cured Conventional Glass Ionomer After Light Emitting Diode Radiant Heat Enhancement
Introduction: Glass ionomer cements (GICs) are widely used in clinical dentistry due to their advantageous properties. However, they present inferior physical and mechanical properties compared to resin composites.
- Trial name
- NCT05744622
- Testing
- KetacTM Universal AplicapTM, KetacTM Universal AplicapTM with light cure
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Caries
Effect of CPP-ACP With/Without Fl on White Spot Lesion,Salivary pH and fl Release in High Caries Risk Patients
Effect of CPP-ACP pastes with/without Fluoride on White spot lesion progression, salivary pH and fluoride release in high caries risk Patients, over 3 month period using VistaCam, Digital pH meter and Selective ion electrode.
- Trial name
- NCT03656432
- Testing
- CPP-ACP paste
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Dental, Risk Reduction
Using a Mouthwash Containing Propolis, Clove Oil and Chlorhexidine to Improve the Caries Risk of High Risk Patients
This study is conducted to determine if using a mouthwash containing propolis, clove oil and chlorhexidine will improve the caries risk of high risk patients in comparison to using a mouthwash containing chlorhexidine only.
- Trial name
- NCT03553628
- Testing
- Chlorhexidine, Propolis and Clove Oil mouthwash, Chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Moataz Gamal Ali Abdul-Maksoud Konsouh
Dental Restoration Failure
Clinical Performance of Bioactive Restorative Material Versus Glass Hybrid Restorative in Posterior Restorations
Clinical performance of bioactive restorative material versus glass hybrid restorative in posterior restorations of high caries risk patients will be evaluated over 12 months using Fédération Dentaire Internationale' (FDI)…
- Trial name
- NCT03608306
- Testing
- Resin-modified glass ionomer, Bulk-fill glass hybrid restorative
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Cervical Caries
The Effectiveness RMGI and Giomer, Individually and Combined Anterior Cervical Caries
This study compares the effectiveness of three dental materials for restoring anterior cervical caries in high-risk patients: resin-modified glass ionomer (RMGI), Giomer, and a combination technique where RMGI is veneered with…
- Trial name
- NCT06901453
- Testing
- Low shrinkage Giomer restorative material (Beautifil II LS), RMGI alone - Control
- Volunteers
- 75 people
- Sponsor
- Cairo University