Clinical trials: High Flow Nasal Cannula
Respiration, Artificial
A SBT-based Protocol-directed Program in Difficult-to-Wean Patients
Weaning patients from a ventilator is one of the most challenging processes in an intensive care unit. The investigators aimed to determine whether spontaneous breathing trial (SBT)-based protocol-directed weaning combined with…
- Trial name
- NCT05035355
- Testing
- a weaning protocol
- Where
- China
- Volunteers
- 200 people
- Sponsor
- JinyanXing
Post Extubation Respiratory Failure
The Effectiveness of High-flow Nasal Cannula After Extubation in Patients
Observe the current status of prolonged mechanical ventilation (PMV) patients using high-flow nasal cannula oxygen therapy (experimental group) or traditional oxygen therapy (control group) after extubation, and compare the…
- Trial name
- NCT06746363
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Chang Gung Memorial Hospital
High-flow Nasal Cannula, Children
Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Randomized Controlled Clinical Trial
Compared with adults, children have higher metabolic needs, and the airway is more likely to collapse. Before tracheal intubation after anesthesia induction, the patient 's spontaneous breathing completely disappears.
- Conditions
- High-flow Nasal Cannula, Children, Pre-oxygenation
- Trial name
- NCT06425406
- Testing
- high-flow nasal cannula
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Colonoscopy
High Flow Nasal Cannula in Patients Undergoing Colonoscopy
During colonoscopy, the insertion of the fiberscope and colon distension required to perform the examination may induce modifications to respiratory mechanics, respiratory effort and breathing pattern.
- Trial name
- NCT05687045
- Testing
- High Flow Nasal Cannula, Conventional Oxygen Therapy
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University Magna Graecia
SARS-CoV Infection, SARS (Severe Acute Respiratory Syndrome)
High Flow Nasal Cannula HFNC In Covid-19 Patients
Many non-invasive ventilatory choices are available for COVID-19 patient who are having mild to moderate respiratory distress and their use will decrease the chance of ICU admission, intubation and mechanical ventilation in…
- Trial name
- HFNC19LGH (NCT04560257)
- Testing
- High flow nasal cannula HFNC
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Lahore General Hospital
Chronic Obstructive Pulmonary Disease, High-flow Nasal Cannula
High-flow Nasal Cannula Nebulization of Beta 2 Adrenergic Agonist During Acute Exacerbation of Chronic Obstructive Pulmonary Disease
High-flow nasal cannula is an oxygenation technique increasingly used for patients admitted for acute respiratory failure. Literature essentially concerns "de novo" acute hypoxemic failure and the interest of high-flow during…
- Trial name
- OPTINEB (NCT03449056)
- Testing
- salbutamol
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Poitiers University Hospital
Respiratory Insufficiency, Pneumonia
High Flow Nasal Cannulae vs Venturi Mask in Respiratory Failure Due to Pneumonia
The primary objective of this study is to compare the efficacy of treatment with HFNC (group A) compared to administration of oxygen therapy by Venturi mask (group B, standard therapy) in terms of reaching of endotracheal…
- Trial name
- HiFlOViP (NCT03515031)
- Testing
- High Flow Nasal Cannula Oxygenation, Venturi Mask Oxygenation
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Papa Giovanni XXIII Hospital
Hypoxemia
The Effects of Flow Settings During High Flow Nasal Cannula for Adult Hypoxemia Patients
High flow nasal cannula (HFNC) delivers oxygen at a flow which exceeds the patient's inspiratory flow demand in order to improve oxygenation.
- Trial name
- NCT03738345
- Testing
- HFNC flow
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Rapid Sequence Induction (RSI), Preoxygenation
High Flow Oxygen in Preoxygenation During Rapid Sequence Induction in Infants and Small Children
Airway management is crucial part of the anaesthesia. There is always a considerable risk of complications or even failure during the anaesthesia induction and airway management.
- Trial name
- PRSIHFO (NCT05846919)
- Testing
- face-mask preoxygenation, HFNOC preoxygenation, HFNOC + face-mask preoxygenation
- Where
- Czechia
- Volunteers
- 4 people
- Sponsor
- Brno University Hospital
Bronchiolitis
Pulmonary Aeration and Muscle Thickening Fraction: Association of Electrical Impedance Tomography and Ultrasound
The goal of this prospective clinical study is to evaluate the effect of different High Flow Nasal Cannula (HFNC) flow rates on diaphragm, rectoabdominal, and oblique thickening fraction, and to determine whether this effect…
- Trial name
- NCT06376487
- Testing
- Flow rate evaluation
- Where
- Brazil
- Volunteers
- 82 people
- Sponsor
- Hospital Israelita Albert Einstein
Respiratory Failure
Preoxygenation in the Intensive Care Unit Using a Nose-mouth Mask Versus High-flow Nasal Cannula Oxygen.
Preoxygenation is routinely performed before endotracheal intubation. In the intensive care unit, preoxygenation is often accomplished using a nose-mouth mask.
- Trial name
- NCT01994928
- Testing
- Nose-mouth mask, High flow nasal cannula oxygen, Intubation
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Bronchiolitis, Respiratory Failure (Pediatric Patients)
Nurse-led High-flow Nasal Cannula Weaning Protocol in Pediatric Intensive Care Unit
Bronchiolitis is a leading cause of pediatric hospital admissions. Despite its limited clinical benefits, the use of HFNC in children with bronchiolitis is increasing.
- Conditions
- Bronchiolitis, Respiratory Failure (Pediatric Patients), High Flow Nasal Cannula
- Trial name
- NCT06621641
- Testing
- The new HFNC weaning protocol
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Severe Obesity Design as BMI > 35kg/m2
Preoxygenation Optimisation in Obese Patients
Oro-tracheal intubation in operating room in obese patients with BMI > 35kg/m2 remains a critical event. The aim of this study is to determine whether Nasal High Flow Therapy by nasal cannula Optiflow® is more efficient than the…
- Trial name
- PREOPTI-POOP (NCT03106441)
- Testing
- High flow oxygen therapy by nasal cannula. Optiflow®, Facial mask oxygenation in BIPAP ventilation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
High-flow Nasal Cannula, Electrical Impedance Tomography
Effects of High-Flow Nasal Cannula Therapy Assessed by Electrical Impedance Tomography
This study aimed to determine the effects of HFNC therapy on lung recruitment and lung strain change assessed by electrical impedance tomography (EIT)
- Trial name
- NCT04245241
- Testing
- High-flow nasal cannula (HFNC)
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Peking Union Medical College Hospital
Anesthesia Morbidity
HIFLO ENDO-High Flow Nasal Cannula in GI Endoscopy
Millions of patients undergo upper GI endoscopy in the United States each year. A large number of these patients have anesthesia to assist with their comfort during the procedure.
- Trial name
- NCT03028688
- Testing
- High flow nasal cannula oxygen
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Neonatal Respiratory Distress Syndrome
Heated, Humidified High-flow Nasal (HHHFN) Cannula vs Nasal Continuous Positive Airway Pressure in Respiratory Distress in Premature Neonates
Newborn babies who have difficulty breathing may need breathing support to help them receive enough oxygen. Two commonly used methods are heated, humidified high-flow nasal cannula (HHFNC), which delivers warmed, moist air and…
- Trial name
- NCT07891494
- Testing
- Heated Humidified High-Flow Nasal Cannula therapy, nCPAP
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Respiratory Failure With Hypercapnia, Therapeutic Bronchofiberoscopy
To Assess the Types of Mechanical Ventilation in Enabling Therapeutic Bronchofiberoscopy in Patients With Decompensated Respiratory Acidosis (Complete Respiratory Failure).
Background: Bronchofiberoscopy (FOB) is a minimally invasive and safe procedure performed for diagnostic and therapeutic purposes.
- Trial name
- NCT06970041
- Testing
- Use of NIV during therapeutic FOB as a respiratory support method in patients with type 2 respiratory failure, Use of HFNC during therapeutic FOB as a respiratory support method in patients with type 2 respiratory failure
- Volunteers
- 315 people
- Sponsor
- Medical University of Silesia
High Flow Nasal Cannula, Oxygen Therapy
Closed-loop Oxygen Control for High Flow Nasal Therapy
In patients with acute hypoxemic respiratory failure (AHRF), High Flow Nasal Therapy (HFNT) improves oxygenation, tolerance, and decrease work of breathing as compared to standard oxygen therapy by facemask.
- Conditions
- High Flow Nasal Cannula, Oxygen Therapy, Hypoxemia, Hyperoxemia
- Trial name
- HILOOP (NCT04965844)
- Testing
- Oxygen close-loop, No intervention
- Where
- Spain
- Volunteers
- 53 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
COPD Exacerbation
Heated High Humidity After COPD Exacerbation
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease usually caused by exposure to tobacco smoke which leads to chronic symptoms of shortness of breath, cough, and phlegm.
- Trial name
- NCT03772626
- Testing
- Heated Humidified High-flow Nasal Cannula
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Acute Respiratory Distress Syndrome Caused by COVID-19
Comparison of High Flow Nasal Cannula (HFNC), Face-mask Non-Invasive Ventilation (NIV) & Helmet NIV in COVID-19 ARDS Patients
Objective: To determine whether NIV delivered through helmet interface reduces intubation rate among patients with COVID-19 ARDS compared to face-mask NIV and HFNC.
- Trial name
- NIV COVID19 (NCT04715243)
- Testing
- High flow nasal cannula (HFNC), Helmet NIV, Face-mask NIV
- Where
- Oman
- Volunteers
- 161 people
- Sponsor
- Sultan Qaboos University