Clinical trials: High-Flow Nasal Cannula
Healthy
Tomographic Comparison of Aerosol Lung Distribution With Two Nebulizers Through a High Flow Nasal Cannula
Vibrating-mesh nebulizers ensure currently the best deposition output and are recommended in routine use in intensive care unit. However, jet nebulizers remain the most frequently used nebulizers.
- Trial name
- NCT02429817
- Testing
- Technetium-99m - Diethylenetriaminepentaacetic acid, Aeroneb Solo, Jet Nebulizer
- Where
- Belgium
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cardiogenic Pulmonary Edema
Helmet CPAP Versus HFNC in Acute Cardiogenic Pulmonary Edema
This study objectively held to compare the physiological outcomes in the non-invasive (NIV) treatment of Acute Cardiogenic Pulmonary Oedema (ACPE) patients in the Emergency Department (ED) delivered by Helmet CPAP (hCPAP) and…
- Trial name
- HCPAPvsHFNC (NCT04005092)
- Testing
- hCPAP versus HFNC
- Where
- Malaysia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Hospital Raja Permaisuri Bainun
Healthy
A Physiological Study to Assess Awake Prone Positioning and Respiratory Support in Healthy Volunteers
Awake prone positioning (APP) has been proven to reduce the intubation rate for patients with COVID-19-induced hypoxemic respiratory failure.
- Trial name
- NCT05512585
- Testing
- awake prone positioning with advanced respiratory support (high-flow nasal cannula or continuous positive airway pressure)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Healthy
Effects of High Flow Nasal Cannula on Breathing and the Respiratory System Parameters
The aim of this study is a detailed investigation of the effect of High Flow Nasal Oxygenation (HFNO) on respiratory system characteristics and ventilation parameters in healthy adult subjects and the subsequent use of measured…
- Trial name
- HaFo (NCT04004247)
- Testing
- High Flow Nasal generator (AirVO2)
- Where
- Czechia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Morbid Obesity, Noninvasive Ventilation
Use of High Flow Nasal Cannula During Sedation of Morbidly Obese Patients in the Endoscopy Suite
This study evaluates the ability of high flow nasal cannula versus nasal cannula to oxygenate morbidly obese patients undergoing moderate to deep sedation for gastrointestinal procedures.
- Conditions
- Morbid Obesity, Noninvasive Ventilation, Deep Sedation
- Trial name
- NCT02859597
- Testing
- High flow nasal cannula, Nasal Cannula
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Neonatal Respiratory Distress
A Comparative Study Between Postextubation of Preterm Infants Into High-Flow Nasal Cannulae V.S Nasal Continuous Positive Airway Pressure
The investigators hypothesize that there is a growing trend of the feasibility of HFNC as an alternative to other forms of non-invasive ventilation mechanism to provide continuous distending pressure to preterm infants.
- Trial name
- NCT04051762
- Testing
- High flow nasal cannula vs. Nasal continuous positive airway pressure
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ramy Saleh Morsy
High Flow Nasal Cannula
Work of Breathing and Oxygen Saturation in Infants Receiving High Flow Nasal Cannula (HFNC)
The purpose of this study is to compare work of breathing on different levels of high flow respiratory support on infants born between 27 and 37 weeks gestation.
- Trial name
- NCT03529994
- Testing
- Enrollment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Respiratory Rate
Respiratory Rate Measured by Pressure Variation During HFNC
Monitoring the respiratory rate is important during procedural sedation. Several methods of measuring the respiratory rate are available, but most are unreliable and the most reliable method (capnography) is not available during…
- Trial name
- NCT05991843
- Testing
- Instructions of breathing
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Oxygen, pH
Comparison of the Effects of High-flow Nasal Cannula Oxygen and Jet Ventilation Techniques
Endoscopic microsurgical procedures of the larynx (direct examination-bx, microlaryngeal resection) require the anesthesiologist and surgeon to work in the same area throughout the procedure, and while ventilation is provided…
- Conditions
- Oxygen, pH, End-tidal Carbon Dioxide
- Trial name
- NCT05746949
- Testing
- oxygenization techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Sedation Complication
Comparison of High-Flow Nasal Cannula Oxygen Application and Classic Nasal Cannula Oxygen Application
Recently, sedation practices have increased for diagnostic and interventional procedures for children in non-operating rooms. On the other hand, the rate of respiratory complications especially in non-operating room sedation…
- Trial name
- NCT04472273
- Testing
- high-flow nasal cannula / classic nasal cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Healthy
The Effects of Different Flow Settings on Lung Impedance
This prospective, randomized crossover trial will enroll adult healthy volunteers. Initially, the subject's peak inspiratory flow will be measured using a mask connected with a respiratory monitor.
- Trial name
- NCT06228703
- Testing
- High-flow nasal cannula device with flow setting at 40 L/min or higher
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Pediatric Asthma
High Flow Nasal Cannula Rates in Pediatric Asthma
This is a randomized, open-label, 3-armed feasibility trial will examine conventional oxygen therapy (COT) vs high flow nasal cannula at 4L/min flow vs HFNC at 2L/kg/min flow (max 60L/min) in moderate to severe pediatric asthma…
- Trial name
- NCT06379607
- Testing
- "High Flow" High Flow Nasal Cannula, "Low Flow" High Flow Nasal Cannula
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Morbid Obesity
Nasal High Flow in Bariatric Surgery
High frequency nasal cannula (HFNC) provides an inspiration O2 fraction of 21-1% and it has a minimal dead space and can be well tolerated due to humidified air.
- Trial name
- NCT04048798
- Testing
- Oxygen therapy via HFNC, Oxygen therapy via face mask
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Hypoxemia
The Effects of Flow Settings During High Flow Nasal Cannula for Adult Hypoxemia Patients
High flow nasal cannula (HFNC) delivers oxygen at a flow which exceeds the patient's inspiratory flow demand in order to improve oxygenation.
- Trial name
- NCT03738345
- Testing
- HFNC flow
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Chronic Obstructive Pulmonary Disease Moderate, Obesity
Aerosol Therapy in Obese COPD Patients.
This study has the objective to clarify the factors that directly influence the effectiveness of inhaled drug deposition in obese patients with chronic obstructive pulmonary disease (COPD) and suggest the use of High Flow Nasal…
- Trial name
- NCT03031093
- Testing
- inhalation protocol, High Flow Nasal Cannula
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
High-flow Nasal Cannula, Intravenous Sedation
High Flow Nasal Cannula in Patients Undergoing ERCP Retrograde Cholangiopancreatography With Intravenous Sedation.
The aim of the current study is to compare the incidence of oxygen desaturation in patients receiving HFNC at different flow rates compared to conventional oxygen therapy via a simple cannula during ERCP.
- Trial name
- NCT04184089
- Testing
- High flow nasal cannula (15 L/m), High flow nasal cannula (30 L/m), High flow nasal cannula (60 L/m)
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Compare Preoxygenation Methods in Bariatric Patients
Preoxygenation With High Flow Nasal Cannula Prolongs Normoxia Time During Induction of Anaesthesia of Bariatric Patients and is Superior to Conventional Preoxygenation With Face Mask.
To compare preoxygenation for induction of general anaesthesia with High Flow Nasal Cannula vs preoxygenation with face mask in patients undergoing bariatric surgery.
- Trial name
- NCT04965610
- Testing
- Preoxygenation with High Flow Nasal Cannula, Preoxygenation via face mask
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Staedtisches Klinikum Karlsruhe
Respiratory Disease (Clinically Stable Individuals - Patients Recovered From Respiratory Disease)
The Effect of Asymmetrical vs. Symmetrical High Flow Nasal Cannula on the Work of Breathing
The goal of this study randomized single-center crossover study is to evaluate the impact of asymmetrical versus symmetrical nasal high flow (NHF) therapy on work of breathing (WOB). The main question it aims to answer are: 1.
- Trial name
- NCT07066566
- Testing
- Asymmetric nasal cannula - DUET, Conventional nasal high flow cannula
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Larissa University Hospital
Swallowing Disorder, Respiratory Insufficiency
The Impact of High-Flow Nasal Cannula on Swallow Function
Background: High-flow nasal cannula (HFNC) is a non-invasive heated and humidified oxygen delivery device that is capable of delivering high-flow rates.
- Trial name
- NCT03590457
- Testing
- Airvo 2; High-Flow nasal cannula system
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Transmission, Patient-Professional
Different Modalities in Reducing Airborne Particulate Concentrations During AGP for Health Volunteers
Several clinical procedures have been described as aerosol generating procedure (AGP), including nebulization, high-flow nasal cannula oxygen therapy, noninvasive ventilation, and bronchial hygiene treatment, etc.
- Trial name
- NCT04681599
- Testing
- Filter, Scavenger face tent
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center