Clinical trials: Hip Osteoarthritis
Osteoarthritis
Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.
The objective of this study is to assess the safety and efficacy of the buprenorphine transdermal system (5, 10, and 20 mg) in comparison to placebo transdermal system in subjects with osteoarthritis pain.
- Trial name
- NCT00314652
- Testing
- Buprenorphine transdermal delivery system
- Where
- 22 sites in United States
- Volunteers
- 260 people
- Sponsor
- Purdue Pharma LP
Osteoarthritis, Traumatic Arthritis
EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))
The purpose of this research is to gather clinical and radiographic (X-ray) information about EMPHASYS™ acetabular shell (also called a hip 'cup') placement in total hip replacement surgery using a non-invasive surgical…
- Conditions
- Osteoarthritis, Traumatic Arthritis, Rheumatoid Arthritis, Congential Hip Dysplasia
- Trial name
- NCT06631638
- Testing
- EMPHASYS Cup with VHN
- Where
- 2 sites in United States
- Volunteers
- 118 people
- Sponsor
- DePuy Orthopaedics
Joint Disease
Post Market Clinical Follow-Up Study Protocol for PROFEMUR® Gladiator HA Coated Modular Femoral Stems
MicroPort Orthopedics (MPO) is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) and resurfacing components marketed in the European Union (EU).
- Trial name
- NCT02314611
- Testing
- PROFEMUR® Gladiator HA Coated Modular Femoral Stem
- Where
- Belgium
- Volunteers
- 154 people
- Sponsor
- MicroPort Orthopedics Inc.
Patellofemoral Osteoarthritis
Effect of Hip and Core Muscle Strengthening for Patellofemoral Osteoarthritis: A Feasibility Study
The purpose of this research is to develop and test the feasibility of an exercise intervention for persons with painful knee osteoarthritis involving the patella (kneecap).
- Trial name
- NCT02825238
- Testing
- Supervised exercise program
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Sciences in Philadelphia
Osteoarthritis, Hip
Clinical Outcomes Following Total Joint Replacement With Corin Prostheses: Corin MetaFix Collared Stem
Assessment of the clinical performance and survivorship of the Corin Total Hip System with Trinity™ cup MetaFix™ Collared stem in a prospective study.
- Trial name
- NCT05121636
- Testing
- MetaFix Collared Stem
- Volunteers
- 51 people
- Sponsor
- Corin
Osteoarthritis
Preoperative Resistance Training in Patients Scheduled for Total Hip Arthroplasty
Purpose: The purpose of this study is to determine the effect of pre operative resistance training on subjects scheduled for total hip arthroplasty due to primary osteoarthritis.
- Trial name
- NCT01164111
- Testing
- Preoperative resistance training
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Osteoarthritis, Vitamin D Deficiency
Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA)
The purpose of this study is being conducted to determine whether correcting low levels of vitamin D with a single high-dose supplement reduces complications after the participant's primary TJA.
- Trial name
- NCT07006714
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Miami
Hip Osteoarthritis
Kinematics and Muscle Strength in Two, Five or 10 Years Afther Total Hip Arthroplasty
Introduction: Femoral and acetabular replacement is characterized as total hip arthroplasty (THA). It has been used as treatment of various pathologies of this joint.
- Trial name
- Arthroplasty (NCT04214171)
- Testing
- Gait and muscle strength will be assessed
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Osteoarthritis, Knee, Osteoarthritis, Hip
To Assess the Patients' Ability to Self-Administer Fasinumab
The primary objective is to demonstrate that the auto-injector(AI) is suitable to be used to administer fasinumab at home by patients or their caregivers, as measured by collecting 12 weeks of actual-use data on the technical…
- Trial name
- FACT DEVICE (NCT03491904)
- Testing
- Fasinumab AI, Fasinumab PFS
- Where
- 23 sites in United States
- Volunteers
- 100 people
- Sponsor
- Regeneron Pharmaceuticals
Degenerative Joint Disease, Avascular Necrosis
A Study on M2a Magnum Total Hip Arthroplasty
The purpose of this study includes the investigation of Metal-ion release and Renal Function analysis in M2a Total Hip Arthroplasty.
- Trial name
- NCT01010763
- Testing
- Total Hip Arthroplasty
- Where
- Japan
- Volunteers
- 184 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee, Osteoarthritis, Hip
A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform
Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a…
- Trial name
- NCT03737149
- Testing
- mymobility with Apple Watch
- Where
- 30 sites in United States, Australia and 2 more
- Volunteers
- 6,559 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Hip
Efficacy and Safety Study of Lumiracoxib in Patients With Primary Hip Osteoarthritis
The purpose of this study is to evaluate the efficacy, tolerability, and safety of the investigational drug, lumiracoxib as compared to celecoxib and placebo in subjects with hip osteoarthritis.
- Trial name
- NCT00154219
- Testing
- Lumiracoxib (drug)
- Where
- 5 sites in United States, Canada and 3 more
- Volunteers
- 1,200 people
- Sponsor
- Novartis
Hip and Knee Joint Osteoarthritis, Hip and Knee Joint Arthroplasty
Effectiveness of Exercise Programs Following Total Hip and Knee Joint Arthroplasty
The purpose of the study was to evaluate the effectiveness of balance exercises added to typical joint range of motion and muscle strengthening exercises on balance in patients following total hip or knee joint arthroplasty
- Trial name
- NCT01555307
- Testing
- Typical range of motion and muscle strengthening exercises, and balance exercises, Typical group
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Total Hip Arthroplasty (THA), Hemiarthroplasty
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Primary Hip Prosthesis System
This is a multicenter, prospective, observational, post-market clinical follow-up (PMCF) study designed to evaluate the safety and clinical performance of the Tipmed™ Primary Hip Prosthesis System in adult subjects undergoing…
- Conditions
- Total Hip Arthroplasty (THA), Hemiarthroplasty, Osteoarthritis (OA) of the Hip, Femoral Neck Fractures
- Trial name
- NCT07651735
- Testing
- Tipmed™ Primary Hip Prosthesis System
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.
Hip Arthrosis, Femur Head Necrosis
Difference in Return to Sports Activity After Hip Arthroplasty by THR or Resurfacing
This study aims to evaluate the return to activity in younger patients under 50 years old after undergoing either total hip replacement (THR) or hip resurfacing, as performed in everyday practice.
- Trial name
- PTH-50 (NCT06410079)
- Testing
- total hip replacement
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Société Française de chirurgie de la Hanche et du Genou
Osteoarthritis, Hip
MONOVISC for Hip Joint Pain Relief Due to Osteoarthritis
Obtain real world, post market data to confirm the clinical improvement and safety in patients treated with a single injection of MONOVISC for the symptomatic relief of osteoarthritis in the hip joint.
- Trial name
- NCT04204083
- Testing
- Monovisc
- Where
- 4 sites in Czechia, Poland
- Volunteers
- 25 people
- Sponsor
- Anika Therapeutics, Inc.
Osteoarthritis, Hyperthyroidism
Povidone Iodine Irrıgation at Hip-Knee Arthroplasty
Povidone iodine (PI) solution is an antimicrobial solution that can be used at hip and knee arthroplasty cases. It contains iodine that may be absorbed by the body.
- Conditions
- Osteoarthritis, Hyperthyroidism, Iodine Toxicity
- Trial name
- NCT05599841
- Testing
- PI solution, Saline Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Osteoarthritis, Leg Length Difference
The Influence of Leg Length Discrepancy After Total Hip Arthroplasty on Function and Quality of Life
Leg length discrepancy (LLD) is a complication of THA and may result in patient dissatisfaction, gait disorder, greater trochanter pain, low back pain. In the literature, LLD is reported to vary widely among studies e.g.
- Conditions
- Osteoarthritis, Leg Length Difference, Hip Arthroplasty
- Trial name
- BioHipLLD (NCT02275494)
- Testing
- Total hip arthroplasty
- Volunteers
- 174 people
- Sponsor
- Sundsvall Hospital
Osteoarthritis, Hip, Traumatic Arthritis of Hip
Total Hip Replacement With the Answer® Hip Stem and Ranawat/Burnstein® Shell Using Simplex® or Palacos® Bone Cement
The purpose of this study is to document the clinical outcomes of several devices used in total hip replacement, including the Answer® hip stem, the Ranawat/Burnstein® acetabular shell, and Simplex® or Palacos® bone cement.
- Trial name
- NCT00588861
- Testing
- Answer® hip stem
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Biomet Orthopedics, LLC
Osteoarthritis
A Study of Pain Relief in Osteoarthritis
The purpose of this study is to compare the safety and pain-relieving ability of Vicodin CR to placebo in subjects with osteoarthritis (OA) of the hip or knee.
- Trial name
- NCT00298974
- Testing
- hydrocodone / acetaminophen extended release
- Where
- 83 sites in United States
- Volunteers
- 873 people
- Sponsor
- Abbott
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