Clinical trials: Hospital Medicine
Medication Administered in Error
Preventing Drug Errors Related to Caregiver Interruptions
Serious medication administration errors are common in hospitals and nurse's interruptions during medication preparation and administration is associated with errors.
- Trial name
- PERMIS (NCT03062852)
- Testing
- Medication safety vest
- Where
- France
- Volunteers
- 15,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Renal Dialysis, Sleep Initiation and Maintenance Disorders
Observation on the Effect of Auricular Acupoint Pressing on Insomnia and Adverse Events in MHD
Maintenance hemodialysis (MHD) is one of the most important treatments for patients with end-stage renal failure. Studies have found that insomnia is widespread in MHD patients, affecting their quality of life.
- Trial name
- NCT03997058
- Testing
- Auricular point pressure therapy, Oral estazolam medication
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine
Acute Myocardial Infarction
Investigating Variation in Hospital Acute Coronary Syndrome Outcomes
To investigate the causes of hospital variation in outcomes from acute coronary syndromes in England and develop recommendations for improving patient care.
- Trial name
- NCT01808027
- Where
- United Kingdom
- Volunteers
- 5,555 people
- Sponsor
- University of Leeds
Smoking Cessation
Nicotine Replacement Provided at a Tertiary Care Hospital
The purpose of this study is to show that a patient-centered survey asking about smoking habits, with the option for nicotine replacement therapy (NRT) will increase the prescription rates among health care providers (HCP).
- Trial name
- N-PATCH (NCT01614054)
- Testing
- Survey of patient's smoking habits
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Medication Adherence, Mobile Application
Mobile Application to Enhance Medication Management
Adverse drug events (ADEs) are a leading cause of death in North America, with over 2 million ADEs causing 100,000 deaths every year and millions in economic costs.
- Trial name
- SAM (NCT04676165)
- Testing
- Smart About Meds (SAM)
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- McGill University
Cohort Study, Natural Population
Tianshan Community Cohort Establishment and Follow-up
This population-based cohort study on disease prevention and health promotion was established in northwest China, leveraging data from routine annual health examinations.
- Conditions
- Cohort Study, Natural Population, Northwest Region of China
- Trial name
- NCT07207863
- Where
- China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- People's Hospital of Xinjiang Uygur Autonomous Region
Medication Review, Polypharmacy
Medication Review in Chronic Complex or Polymedicated Patients After Hospital Discharge.
The goal of this prospective multicentre clustered randomized controlled trial is to evaluate the effect on new hospitalization episodes of a multidisciplinary medication review in primary care patients with polypharmacy or…
- Conditions
- Medication Review, Polypharmacy, Disease, Chronic
- Trial name
- NCT05799430
- Testing
- Multidisciplinary medication review, Control group
- Where
- Spain
- Volunteers
- 372 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Total Hip Arthroplasty
Analysis of Clinical Effect of Subanesthetic Dose of Esketamine Combined With Hip Capsule Peripheral Nerve Block in Elderly Patients Undergoing Total Hip Arthroplasty
To observe the clinical effect of esketamine combined with hip capsule peripheral nerve block in elderly patients undergoing total hip arthroplasty.
- Trial name
- NCT05602428
- Testing
- esketamine sub-anesthetic,, esketamine sub-anesthetic
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Changzhou Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine
Medication Review, Polypharmacy
Prioritising Patient Medication Review: Hospitals Reaching Out
To examine the effect of a cross-sectoral medication review intervention to admitted multi-morbid, polypharmacy patients aged 65+ at SHS in two settings; an acute admission unit (typical admission time < 48 hours) and a medical…
- Conditions
- Medication Review, Polypharmacy, General Practitioners, Interdisciplinary Communication
- Trial name
- PriPMed (NCT06451692)
- Testing
- Clinical pharmacist
- Where
- Denmark
- Volunteers
- 800 people
- Sponsor
- University of Southern Denmark
COVID-19, Allergic Rhinitis
the Relationship Between Allergic Rhinitis and the Risk of Symptom in Patients With Mild COVID-19
At present, most studies mainly focussed on severe patients, and there was no comparison of symptom differences between AR patients and healthy people with mild infection to evaluate the symptoms of AR patients during infection…
- Trial name
- NCT05753241
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- qinxiu zhang
Multi Drug Resistant Infections, Pneumnia
Traditional Chinese Medicine in Multidrug-Resistant Bacterial Pneumonia
This is a multicenter prospective observational cohort study involving hospitalized adult patients with multidrug-resistant bacterial pneumonia.
- Trial name
- MDRBP-TCM (NCT07726095)
- Where
- China
- Volunteers
- 652 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Adverse Drug Events
Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care
This initiative aims to decrease the risk of medication errors at the hospital-community interface as well as health system utilization following hospital discharge by implementing a pharmacist-led medication reconciliation in…
- Trial name
- CMR (NCT01164137)
- Testing
- Medication Reconciliation
- Where
- Canada
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Westview Physician Collaborative
Polypharmacy, Pharmacogenetics
Individual Risk Profiles for Adverse Drug Reactions in Geriatric Patients
This project will generate a prospective cohort of geriatric patients with polypharmacy which will be characterized for vulnerability profiles of adverse drug reactions.
- Conditions
- Polypharmacy, Pharmacogenetics, Pharmacogenomic Testing, Drug-Related Side Effects and Adverse Reactions
- Trial name
- NCT05247814
- Testing
- Pharmacogenomic testing of a panel of important pharmacogenes to detect genetic variants and evaluate the association between genetically predicted and measured drug metabolism, Adverse Drug Reaction detection, Falls Efficacy Scale International (FES-I)
- Volunteers
- 2,000 people
- Sponsor
- RWTH Aachen University
Carbapenem Resistant Klebsiella Pneumoniae
Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital
The patients who infected with Carbapenem resistant Klebsiella pneumoniae were high mortality rate. Appropriate antibiotics therapy adjusted by Pharmacokinetic/Pharmacodynamic plays an important role in determining outcomes in…
- Trial name
- NCT05862402
- Testing
- Dose-adjustment by PKPD
- Where
- Thailand
- Volunteers
- 76 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Total Knee Arthroplasty; Total Hip Arthroplasty
Health Partner Evaluation at Princeton
This is a prospective, single-center, randomized, comparative, controlled study. Penn Medicine Princeton Medical Center will enroll a total of 296 subjects (18 years or older) who are electing to have total knee or hip…
- Trial name
- NCT03386786
- Testing
- Health Partner, Standard Care
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- DePuy Orthopaedics
Premature Ventricular Contraction
Remote Magnetic Versus Manual Navigation-guided Ablation for Non-outflow Tract Premature Ventricular Contractions: a Prospective, Randomized, Controlled Trial
This prospective, randomized, controlled trial is designed to compare the safety and efficacy of remote magnetic navigation-guided ablation for ventricular premature complexes arising from non-outflow tracts with manual control…
- Trial name
- NCT04519112
- Testing
- Catheter Ablation
- Volunteers
- 200 people
- Sponsor
- Ruijin Hospital
3 or More Chronic Conditions for 6 Months or Longer, 5 or More Regular Drugs
Health Economic Evaluation Alongside the OPERAM Trial
The objective of the health economic evaluation is to perform a state-of-the-art economic analysis of the STRIP intervention, alongside the OPERAM Randomised Controlled Trial (RCT).
- Trial name
- NCT03108092
- Testing
- STRIP intervention, Control
- Where
- 4 sites in Belgium, Ireland and 2 more
- Volunteers
- 2,009 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
QT-prolongation
Drug Interactions With Risk of QT-prolongation in a General Hospital
In this epidemiological point prevalence study, medication profiles of patients with haloperidol treatment will be checked for drug interactions with risk of QT-prolongation.
- Trial name
- NCT02043912
- Testing
- Haloperidol
- Where
- Belgium
- Volunteers
- 222 people
- Sponsor
- KU Leuven
Electronic Prescribing
Evaluation of Electronic Prescribing in Hospital Ambulatory Care Clinics
All reliably evaluated POE systems to date have been desktop computer based, but now there is widespread use and acceptance among physicians of PDA devices for a variety of purposes.
- Trial name
- NCT00252395
- Testing
- PDA-based Electronic Prescribing Software
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Kidney Transplant, Adult
Evaluation of an Instructional Video About Medication Management During Admission and Medication Adherence for Kidney Transplantation and in the Outpatient Clinic in a Dutch University Hospital.
The goal of this RCT is to evaluate the effect of the instructional video on improving patient compliance and reducing medication errors.
- Conditions
- Kidney Transplant, Adult, Medication Adherence, Instruction Videos
- Trial name
- MediT (NCT07592624)
- Testing
- Instructional video about medication administration
- Where
- Netherlands
- Volunteers
- 308 people
- Sponsor
- Erasmus Medical Center