Clinical trials: IBD-Inflammatory Bowel Disease
Inflammatory Bowel Disease
The Altitude Inflammatory Bowel Disease Study
This is a prospective, controlled and observational study. Participants underwent a 3-hour exposure to hypoxic conditions simulating an altitude of 4,000 meters above sea level (m.a.s.l.) in a hypobaric pressure chamber.
- Trial name
- NCT02849821
- Testing
- hypobaric pressure chamber, Sigmoidoscopy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Inflammatory Bowel Disease (IBD)
Gut Microbial Transplantation in Pediatric Inflammatory Bowel Diseases
Inflammatory bowel disease (IBD) is a chronic, debilitating, relapsing inflammatory disorder affecting the gastrointestinal tract which does not have a medical cure.
- Trial name
- GMT (NCT01560819)
- Testing
- Gut Microbial Transplantation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Corewell Health West
Crohn's Disease
A Study of TRK-170 for the Treatment of Crohn's Disease
In Crohn's Disease Patients To evaluate the efficacy of TRK-170 To evaluate the PK characteristics of TRK-170 To assess the safety of TRK-170
- Trial name
- NCT01345799
- Testing
- TRK-170
- Where
- 13 sites in Belgium, Bulgaria and 11 more
- Volunteers
- 123 people
- Sponsor
- Toray Industries, Inc
Inflammatory Bowel Disease (IBD), Ulcerative Colitis (UC)
A Study to Evaluate Non-invasive Measurements of the Inflammatory Status in Patients with IBD
Patients with IBD, including both Crohn's disease and ulcerative colitis, require accurate monitoring of intestinal inflammation for optimal follow-up and treatment.
- Conditions
- Inflammatory Bowel Disease (IBD), Ulcerative Colitis (UC), Crohn Disease (CD)
- Trial name
- VERSATILE (NCT06900738)
- Testing
- Inflammometer
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Crohn Disease
Extracorporeal Photopheresis of Patients With Crohn's Disease Using 5-aminolevulinic Acid
In the clinical trial the investigators will assess efficacy, safety and tolerability after single and multiple doses of 3 millimolar 5 aminolevulinic acid (Gliolan®) in combination with blue-light (405 nanometer) photopheresis…
- Trial name
- NCT04164849
- Testing
- 5-aminolevulinic acid, Blue light photopheresis, Transfusion
- Where
- Norway
- Volunteers
- 7 people
- Sponsor
- University Hospital, Akershus
Crohn's Disease, Ulcerative Colitis
Non Invasive Characterization of Pediatric Inflammatory Bowel Diseases Using Multispectral Optoacoustic Tomography
Monocentric, prospective observational study to assess bowel inflammation in children with chronic inflammatory bowel disease (IBD) using multispectral optoacoustic tomography (MSOT).
- Conditions
- Crohn's Disease, Ulcerative Colitis, IBD
- Trial name
- PED_MSOT_IBD (NCT04650867)
- Testing
- Multispectral Optoacoustic Tomography (MSOT)
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
IBD
Stavanger University Hospital Inflammatory Bowel Disease Trial
The study aims at studying the outcomes of a protocol-based handling of newly diagnosed Inflammatory bowel disease ( IBD ) patients within a defined uptake area in Norway.
- Trial name
- SUSI (NCT01551563)
- Where
- Norway
- Volunteers
- 700 people
- Sponsor
- Helse Stavanger HF
Crohn Disease
Prevention of Postoperative Endoscopic Recurrence With Endoscopy-driven Versus Systematic Biological Therapy
With this prospective, randomized, multicentre, parallel group pragmatic non-inferiority trial, the investigators will evaluate if endoscopy-driven introduction of biological therapy is not leading to more postoperative…
- Trial name
- SOPRANO-CD (NCT05169593)
- Testing
- Biological Drug
- Where
- 28 sites in Belgium, Italy
- Volunteers
- 292 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ulcerative Colitis
Fecal Microbiota Transplantation (FMT) in the Management of Ulcerative Colitis (UC)
Inflammatory bowel disease is a condition caused by gastrointestinal immune system dysregulation and affected by both genetic and environmental factors.
- Trial name
- NCT02516384
- Testing
- Fecal Microbiota Transplantation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Crohn's Disease
Efficacy Study of Tripterygium Glycoside Combined With Enteral Nutrition in the Treatment of Crohn's Disease for Induction Remission
The purpose of this study is to assess the effect of Tripterygium Glycosides Combined with enteral nutrition in the treatment of Crohn's disease for induction remission and compare the therapeutic effect with patients who only…
- Trial name
- NCT01820247
- Testing
- enteral nutrition, Tripterygium glycosides
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhu Weiming
Inflammatory Bowel Disease
Influence of Vitamin D on Inflammatory Bowel Disease Remission
Vitamin D has been shown to influence a multitude of systems. We intend to see whether different types of Vitamin D supplements have an effect on inflammatory bowel disease.
- Trial name
- NCT01121796
- Testing
- Vitamin D, Water or milk, Vitamin D enriched milk
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Hillel Yaffe Medical Center
Colitis, Ulcerative
An Efficacy and Safety Study of Vedolizumab Intravenous (IV) Compared to Adalimumab Subcutaneous (SC) in Participants With Ulcerative Colitis
The purpose of this study is to evaluate the efficacy and safety of vedolizumab intravenous (IV) treatment compared to adalimumab subcutaneous (SC) treatment over a 52-week treatment period.
- Trial name
- NCT02497469
- Testing
- Vedolizumab, Adalimumab
- Where
- 330 sites in United States, Argentina and 32 more
- Volunteers
- 771 people
- Sponsor
- Takeda
Ulcerative Colitis
Investigation of the Effects of Curcumin and Resveratrol Supplements Added to the Mediterranean Diet on Disease Severity and Inflammatory Biomarkers in Patients With Ulcerative Colitis
The aim of the study was to examine and compare the effects of Mediterranean diet, curcumin supplementation with Mediterranean diet in individuals with ulcerative colitis, and resveratrol supplementation with Mediterranean diet…
- Trial name
- NCT05761327
- Testing
- Mediterranean Diet, Curcumin Supplementation, Resveratrol Supplementation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ardahan University
Inflammatory Bowel Diseases
Psychological Predictors in Colorectal IBD Surgery Recovery
This is an observation pilot trial aimed to study to the association between mindfulness and other psychological factors, including both protective and risk factors, with recovery of functional ability following colorectal…
- Trial name
- MIND-IBD (NCT03893942)
- Testing
- Questionnaires administration, Langer Mindfulness Scale (LMS), Mindful Attention Awareness Scale (MAAS)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituto Clinico Humanitas
Crohn Disease
Active Surgical Intervention on Crohn's Disease
The study is to determine whether active surgical intervention promotes disease remission in patients with Crohn's Disease (CD).The management of CD involves both maintenance medication and medication used to control flares of…
- Trial name
- NCT05523050
- Testing
- active surgical intervention
- Volunteers
- 100 people
- Sponsor
- Wuxi People's Hospital
Ulcerative Colitis
Prognostic Value of Confocal Endomicroscopy in Ulcerative Colitis: the CONF-UC Study
This study employs a prospective, single-center, interventional design to investigate the prognostic value of confocal endomicroscopy in assessing treatment response in ulcerative colitis (UC) patients receiving small molecules .
- Trial name
- CONF-UC (NCT06624579)
- Testing
- confocal endomicroscopy
- Volunteers
- 26 people
- Sponsor
- FEDERICA FURFARO
Crohn's Disease
Early Immunosuppressants in Crohn's Disease
Pluricentric randomized study comparing two therapeutic strategies at beginning of Crohn's disease: early immunosuppressants (prescription within the six first months following diagnosis) vs.
- Trial name
- RAPID (NCT00546546)
- Testing
- early immunosuppressants (azathioprine, methotrexate)
- Where
- 26 sites in France
- Volunteers
- 120 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Ulcerative Colitis
Study Evaluating the Long-term Safety and Efficacy of ABX464 in Active Ulcerative Colitis
This study is an open-label study aiming at evaluating the long-term safety and the efficacy profile of ABX464 given once a day (o.d) at 50 mg in subjects who have been previously enrolled in the ABX464-101 clinical study…
- Trial name
- NCT03368118
- Testing
- ABX464
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Abivax S.A.
Crohn's Disease
Clinical Efficacy of TNFa Kinoid in Crohn's Disease Patients
The safety and immunogenicity of the TNFα-Kinoid (TNF-K) have been evaluated in a phase I-II clinical study conducted in subjects with Crohn's Disease (CD). Preliminary results of clinical efficacy are promising.
- Trial name
- NCT01291810
- Testing
- TNF Kinoid, WFI
- Where
- 58 sites in Belgium, Bulgaria and 7 more
- Volunteers
- 66 people
- Sponsor
- Neovacs
Inflammatory Bowel Diseases, Anxiety
Digital Support for Mental Health Intervention in Patients With Inflammatory Bowel Disease
This is a small, exploratory study that will investigate using an artificial intelligence (AI) and virtual reality (VR), digital wellness application (app) to deliver a mental health support session in outpatient and hospitalized…
- Conditions
- Inflammatory Bowel Diseases, Anxiety, Depression, Ulcerative Colitis
- Trial name
- NCT06575660
- Testing
- Mental health support session
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Chicago
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