Clinical trials: IVF
Infertility
Comapring Luteal Phase Support in IVF Patients Who Are at High Risk for Developing OHSS
The purpose of this study is to compare two luteal support protocols in In vitro fertilization patients (IVF) and are at risk of developing ovarian hyperstimulation syndrome (OHSS).
- Trial name
- NCT02827656
- Testing
- Decapeptyl, hCG luteal support
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Fertilization in Vitro, Infertility
The Impact of the Timing of Trigger on IVF Success
The aim of this study is to examine the length of ovarian stimulation with the timing of trigger in an IVF cycle and its potential to impact patient outcomes.
- Conditions
- Fertilization in Vitro, Infertility, Embryonic Development
- Trial name
- NCT02990949
- Testing
- Timing of trigger
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Reproductive Medicine
Adenomyosis
Adenomyosis and ART
The goal of this clinical trial is to: Prospectively investigate the association of Adenomyosis with fertility outcomes in relation to COH protocols for ART (long or ultra- long protocol) with a preventive high-dose…
- Trial name
- ADENOFERT (NCT05937490)
- Testing
- Enantone, Dienogest 2 MG (milligram), long GnRH agonist or flexible GnRH antagonist protocol.
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Female Infertility Due to Nonimplantation of Ovum, Complications Associated With Artificial Fertilization
Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression
The purpose of this study is to assess the non-inferiority of a multidose GnRH antagonist (cetrorelix) regimen to a GnRH agonist (triptorelin) long protocol in young infertile women undergoing ovarian stimulation with Pergoveris…
- Trial name
- Pergoveris (NCT01565265)
- Testing
- Pergoveris in long protocol with GnRH agonist, Pergoveris in GnRH antagonist protocol
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Quality of Life, IVF
CALM IVF (Creating Affiliations, Learning, and Mindfulness for In Vitro Fertilization Patients)
The investigators have designed a psychoeducational group curriculum specifically for new in vitro fertilization (IVF) patients (both male and female) to improve their treatment knowledge, to allow them to engage more in their…
- Conditions
- Quality of Life, IVF, Patient Satisfaction, Patient Engagement
- Trial name
- NCT04048772
- Testing
- CALM IVF, Standard of Care
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Male Infertility
A Novel Sperm Selection Method Provides Advantages Over Conventional Approaches
The goal of this clinical trial is to know if a novel sperm selection device (CA0) has a similar performance than the standard selection method in teratozoospermic and azoospermic men.
- Trial name
- NCT06545318
- Testing
- Density Gradient Centrifugation, CA0 chamber
- Where
- Mexico
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Center of Innovation Technology & Reproductive Medicine
Infertility, Female
Endometrial Compaction in Assissted Reproduction
To record the dynamic change of endometrial thickness (Day of embryo transfer Versus. Day of ovulation trigger administration in case of fresh cycles or end of estrogen phase in frozen cycles), and to investigate the impact of…
- Trial name
- NCT04962789
- Testing
- transvaginal ultrasound on the uterus
- Where
- Egypt
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility
Vaginal Culture Using INVOcell Compared to Traditional IVF Incubation
The purpose of this study is to evaluate intravaginal culture using the medical device INVOcell to generate day 5 blastocysts in comparison to traditional IVF.
- Trial name
- NCT02363426
- Testing
- INVOcell Culture Device, IVF Incubation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Invaron Pharmaceuticals Inc.
Infertility
The Effects of Intrauterine Infusion of hCG at the Time of Embryo Transfer
The purpose of this study is to determine whether intrauterine hCG can improve the implantation rate and clinical pregnancy rate after embryo transfer in IVF/ICSI cycle.
- Trial name
- NCT02668965
- Testing
- Intrauterine hCG (pregnyl)
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mahidol University
INFERTILITY
Dual Triggering in Patients With a High Immature Oocyte Rate
In in vitro fertilization (IVF) cycles, even after adequate triggering, some patients present a high rate of immature oocytes retrieved after controlled ovarian stimulation.
- Trial name
- NCT02813239
- Testing
- hCG, hCG + GnRH agonist
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Infertility
Ultrashort GnRH Agonist/Antagonist Versus GnRH Antagonist IVF
The purpose of this study is to evaluate the appropriate controlled ovarian hyperstimulation (COH) protocol in good prognosis patients undergoing IVF treatment.
- Trial name
- NCT02173977
- Testing
- ARM A- Agonist/Antagonist protocol, ARM B- Antagonist protocol
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Anxiety, in Vitro Fertilization
Impact of Virtual Reality Before Oocytes Retrieval on Anxiety and Pregnancy Rate
The primary objective of this study is to evaluate the impact of a session of virtual reality (VR) with the objective of lowering the anxiety level on the clinical pregnancy rate following an In-vitro fertilisation (IVF)…
- Conditions
- Anxiety, in Vitro Fertilization, Virtual Reality
- Trial name
- NCT03064061
- Testing
- Virtual reality
- Where
- Belgium
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Infertility, Female
Effect of Colony Stimulating Factor on Implantation and Pregnancy Rates Following IVF (in Vitro Fertilization)
This a trial designed to test whether granulocyte colony stimulating factor (G-CSF, Neupogen) can increase the rate of embryo implantation following IVF and embryo transfer.
- Trial name
- NCT01202656
- Testing
- G-CSF, Saline
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Non-viable Oocytes, Extra Spermatozoa
Evaluation of Discarded Laboratory Pathological Specimens and Media
The researchers propose to investigate the causes, incidence, and time-related events of chromosomal and physiologic abnormalities as they relate to patient diagnosis, fertility drugs utilized, and in vitro laboratory culture…
- Conditions
- Non-viable Oocytes, Extra Spermatozoa, Seminal Fluid, Granulosa Cells
- Trial name
- NCT01219439
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility, Female, IVF
RCT to Assess the Impact of Microbiome Status in Infertile IVF Patients at Their First IVF/ICSI Cycle
Although the endometrium has been traditionally considered free of bacteria, recent studies have documented the presence of an endometrial microbiome.
- Trial name
- NCT04686357
- Testing
- EMMA/ALICE
- Volunteers
- 1,018 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Infertility
Freeze All on Oocyte Maturatin by Gonadotropin Agonist Versus Human Chorionic Gonadotroipin
Estradiol valerate in the form of cycloprogenova™ (white tablet only) was started on day 2 or 3 of cycle with oral dose 4 mg divided on 2 doses in addition to Aspocid 75 mg once daily with folic acid 500 mcg once daily.
- Trial name
- NCT04749979
- Testing
- Agonist (decapeptyl ), HCG ( eg. Choriomon )
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Infertility, Subfertility
The Microbiome in Subfertility and Assisted Reproductive Technologies (ART)
To assess the impact of the female genital microbiome on ART outcome.
- Trial name
- NCT03105453
- Testing
- 3 Sampling points
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
ART, Offspring, Adult
IVF Offspring Born in Guangzhou
The IVF Offspring Born in Guangzhou Cohort Study (IVF-BIG) was established to investigate the short- and long-term effects of exposure in early life on the health of mothers and offspring in Guangzhou, China.
- Conditions
- ART, Offspring, Adult, Genetics, Host and Microbiome
- Trial name
- IVF-BIG (NCT03650829)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Midazolam Overdose
Measurement of Midazolam Levels in Follicular Fluid
To determine the impact of Midazolam levels in follicular fluid on morpho-kinetics and morpho-genetics. The reason to measure Midazolam levels in larger size follicles in this study is to maximize the chances to get a mature…
- Trial name
- NCT03049293
- Testing
- Midazolam
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
A Study of the Efficacy and Safety of Highly Purified Menotrophin Versus Recombinant Follitropin Alfa
Prospective open label, randomised, parallel group, comparative pilot.
- Trial name
- NCT00257556
- Testing
- Menotrophin, Follitropin alfa
- Where
- 6 sites in Germany, United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals