Clinical trials: IVF Treatment
Polycystic Ovary Syndrome
A Study to Explore Correlation Between Symptoms and Signs of Polycystic Ovarian Syndrome (PCOS) and Risk of Over-response to Ovarian Stimulation
This is a Phase IV, prospective, observational, single arm, multicenter trial to identify the population at high risk of overstimulation associated with signs and symptoms of PCOS and examines the utility of 12.5 international…
- Trial name
- ARTIST (NCT02607293)
- Testing
- Gonal-f®, Long GnRH agonist, GnRH antagonist
- Where
- Germany
- Volunteers
- 1,064 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Azoospermia, Infertility
Microdissection Testicular Sperm Extraction (MicroTESE) and IVF-ICSI Outcome in Non-Obstructive Azoospermia (NOA)
We evaluated the application of surgical testicular exploration with the aid of a microscope (MictoTESE) to increase the chances of obtaining sperm in men with impaired sperm production, a condition known as non-obstructive…
- Trial name
- NCT00484081
- Testing
- Microdissection Testicular Sperm Extraction, ICSI
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Clinic and Research Center in Human Reproduction Roger Abdelmassih
Infertility, Stress
The Effect of Stress on DNA Integrity and the Effect of Cognitive Behavioral Therapy on Stress and Infertility in Women
The general hypothesis of the research is that stress decreases fertility and that Cognitive Behavioral Therapy will reduce stress and increase fertility.
- Trial name
- NCT00685282
- Testing
- Cognitive Behavioral Therapy
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Soroka University Medical Center
Infertility
Prolongation of Progesterone Supplementation in Antagonist Cycles and Pregnancy Outcomes
The objective of this study is to evaluate the effect of the prolongation of luteal support on the ongoing pregnancy rate (beyond 12 weeks of gestation )in recFSH/GnRH antagonist cycles.
- Trial name
- NCT01147770
- Testing
- progesterone
- Volunteers
- 200 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cancer, Cancer in Pregnancy
ProspectiveFemaleAYA - Late Effects of Cancer Therapies on Gonadal Function, Fertility, Efficiency of Fertility Preservation Procedures and Pregnancy Outcomes
In the past two decades, the evidence-based knowledge on the prevalence and risk factors for gonads impairment, including infertility, following cancer and numerous cancer treatment regimen has significantly increased.
- Conditions
- Cancer, Cancer in Pregnancy, Infertility, In Vitro Fertilisation (IVF) Treatment
- Trial name
- FemFertilAYA (NCT07622420)
- Volunteers
- 3,000 people
- Sponsor
- Karolinska Institutet
Human Papilloma Virus, Infertility, Male
Detection and Prevalence of Human Papillomavirus (HPV) in Seminal Plasma and/or on Sperm in Men Undergoing Treatment With IVF/ICSI.
This observational study aims to investigate the presence of HPV DNA in semen samples from men undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment.
- Trial name
- NCT06161727
- Testing
- HPV exposure
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Vastra Gotaland Region
Endometriosis
Dienogest Versus GnRH-a Pre-treatment in Women With Endometriosis Undergoing IVF
Endometriosis is a chronic gynecologic disease that affects approximately 10% of women in the reproductive age group . It is characterized by the presence of endometrial tissue outside the uterus, causing pelvic pain and…
- Trial name
- NCT03142035
- Testing
- Dienogest 2 MG, gonapeptyl, IVF/IVF+ART
- Where
- Lebanon
- Volunteers
- 189 people
- Sponsor
- American University of Beirut Medical Center
In Vitro Fertilization, Ovarian Stimulation
Age Versus Ovarian Reserve Markers Based Therapy in IVF (IVF)/Intracytoplasmic Sperm Injection (ICSI) Cycles
This randomized controlled trial has been designed for carrying out a comparison of new AMH (Anti-Müllerian Hormone)-based individualized treatment (using a nomogram) with the wide accepted age-based strategy.
- Trial name
- NCT01816789
- Testing
- rFSH, buserelin
- Where
- Italy
- Volunteers
- 194 people
- Sponsor
- Andros Day Surgery Clinic
Infertility
Study to Estimate Seedchrony's Predictive Capacity in the Success of Embryo Implantation.
In Vitro Fertilization (IVF) success is below 40%, with Embryo Transfer the leading cause of IVF failure. This clinical investigation aims to evaluate if the levels of an intrauterine biomarker dissolved in the uterine fluid…
- Trial name
- Seedchrony02 (NCT06259084)
- Testing
- Seedchrony
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Manina Medtech
Infertility, Polycystic Ovarian Syndrome
IVF Versus Gonadotropin Therapy in Women With CC Resistant PCOS
The purpose of this study is to compare the efficacy of in vitro fertilization (IVF) versus gonadotropin therapy in infertile women having clomiphene citrate (CC) resistant polycystic ovarian syndrome (PCOS).
- Trial name
- NCT02458963
- Testing
- IVF, Gonadotropin
- Where
- 2 sites in Egypt
- Sponsor
- Mohamed Sayed Abdelhafez
Overweight or Obesity
Effectiveness of a Digital Behavioral Intervention Program for Overweight and Obese Patients
This study applied digital technology to a comprehensive lifestyle intervention strategy to design a digital behavioural intervention programme suitable for weight reduction in overweight obese infertile patients in China, and…
- Trial name
- NCT07045272
- Testing
- Experimental
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Antichlamydial Antibodies, Chlamydia Trachomatis Infection
Cohort Study Investigating the Association Between Antichlamydial Antibody Positivity and ART Outcomes in Women With TFI
In a prospective cohort study investigators will examine characteristics and clinical outcomes of treatment with ART in women with tubal factor infertility (TFI) with regard to seropositivity to antichlamydial antibodies.
- Conditions
- Antichlamydial Antibodies, Chlamydia Trachomatis Infection, Infertility, Tubal Factor Infertility
- Trial name
- NCT04139629
- Testing
- antichlamydial antibody test, treatment of infertility with ART
- Where
- Russia
- Volunteers
- 292 people
- Sponsor
- D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology
Infertility
Comparison Between hCG and GnRH Agonist for Ovulation Induction in Patients With High Response to IVF Drugs
hCG and GnRH agonist can be used to induce final oocyte maturation and ovulation in IVF cycles. These two approaches will be compared in this study in terms of pregnancy rates and embryological data using patients with…
- Trial name
- NCT00415792
- Testing
- Arvekap, Pregnyl
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eugonia
Couple Sterility
Effect of Myoinositol Treatment of Spermatozoa on in Vitro Fertilization Outcome
In the present trial, the investigators aim to evaluate whether semen myo-inositol (MI) treatment is able to improve IVF outcomes.
- Trial name
- MI_ICSI (NCT02050672)
- Testing
- Myo-inositol, untreated
- Where
- Italy
- Volunteers
- 249 people
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Virtual Reality Therapy, Fertilization in Vitro
Effectiveness of Hypnosis Via Virtual Reality During Oocyte Retrieval
This study compares hypnosis via virtual reality to sedation with commonly used intravenous anesthetic agents (propofol and remifentanil) during oocyte retrieval.
- Conditions
- Virtual Reality Therapy, Fertilization in Vitro, Propofol, Remifentanil
- Trial name
- NCT05244538
- Testing
- Virtual reality distraction, Propofol-remifentanil sedation
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Conventional IVF, ICSI
Child Follow-up in Women Treated With Conventional IVF or ICSI
To compare the physical, mental and motor development of babies born from pregnancy using ICSI technique and and conventional IVF in non-male factor infertile couples.
- Trial name
- NCT04866524
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 322 people
- Sponsor
- Mỹ Đức Hospital
Infertility
Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients
A prospective, randomized, controlled study to explore the efficacy and safety of using either corifollitropin alfa 150 mcg or daily recombinant follicle stimulation hormone (FSH) 300 international unit (IU) for the stimulation…
- Trial name
- NCT02466204
- Testing
- corifollitropin alfa, Follitropin Beta
- Where
- 2 sites in Vietnam
- Volunteers
- 400 people
- Sponsor
- Vietnam National University
Infertility
A Dose-response Trial Using rFSH FE 999049 in Women Undergoing IVF/ICSI Treatment
This trial investigates the effects of several doses of FE 999049 in women undergoing IVF/ICSI (in-vitro fertilisation/intracytoplasmic sperm injection) treatment.
- Trial name
- NCT01426386
- Testing
- FE 999049, Gonal - F
- Where
- 8 sites in Belgium, Czechia and 2 more
- Volunteers
- 265 people
- Sponsor
- Ferring Pharmaceuticals
Infertility Assisted Reproductive Technology
Association Between Serum Progesterone Levels on Embryo Transfer Day and Clinical Pregnancy in Frozen-thawed Embryo Transfer Cycles Using Hormone Replacement Therapy
A retrospective evaluation of routinely collected clinical, embryological, laboratory, and pregnancy outcome data provides an efficient approach to examine the association between serum progesterone on the day of FET and clinical…
- Trial name
- NCT07858227
- Testing
- data collection
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Fertility Issues
Study to Investigate the Treatment Benefit of Probiotic Lactobacillus Crispatus M247 in Women Undergoing Homologous Level 2 Assisted Reproductive Technology (ART) Procedures
The present study is aimed to explore the treatment effect from the intake of probiotic Lactobacillus crispatus M247 in the improvement of clinical and psychological aspects in women undergoing homologous level 2 ART procedures.
- Trial name
- NCT05871242
- Testing
- Probiotic Lactobacillus crispatus M247
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Dr. Amjad Khan