Clinical trials: Imaging Guided
Healthy
Electrophysiological Source Imaging Guided Transcranial Focused Ultrasound
Neuromodulation is a fast growing field that offers a wide range of applications for both understanding and treating the brain. Future research for non-invasive neuromodulation will need to elucidate the optimal frequency…
- Trial name
- NCT03192436
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Lung Cancer
Novel Lung Functional Imaging for Personalized Radiotherapy
The primary objective of this study is to assess the safety and feasibility of personalized radiotherapy with four-dimensional (4D) computed tomography (CT)-based pulmonary ventilation imaging, which selectively avoids…
- Trial name
- NCT02308709
- Testing
- Ventilation image-guided radiotherapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, Davis
Prostatic Diseases
Hypnosis Mask: a New Approach to Management of Pain in Medical Imaging
The prostatic biopsies echo-guided are a painful and stressful. The purpose is to test a new medical device created recently, " Hypnos-Pro ", wich uses connected technologies.
- Trial name
- HYPNOTIC (NCT03711643)
- Testing
- Periprostatic nerve block, hypnosis mask
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Lille
Prostate Cancer
Prostate Cancer Detection Rates of Standard Transrectal Prostate Biopsy and MR-guided Fusion Transrectal Prostate Biopsy
Prostate cancer is the most frequent cancer in men. Today serum prostate specific antigen (PSA) level and digital rectal examination (DRE) are routinely used for screening of prostate cancer.
- Trial name
- NCT03936296
- Testing
- mpMR guided MR-US fusion transrectal prostate biopsy, 12 core standard transrectal prostate biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- TC Erciyes University
Liver Neoplasms
Assessment of Indocyanine Green as a Near-Infrared Fluorescent Contrast Agent for Image-guided Liver Surgery
This is a prospective, monocentric, non-randomized, phase I-II study. The goal is to assess the faisability and the capabilities of fluorescence imaging in hepatic surgery, and specially to help the surgeon while performing liver…
- Trial name
- HEPATOFLUO (NCT01738217)
- Testing
- Fluobeam
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Leon Berard
Carcinoma, Non-Small-Cell Lung
Study Using Induction Chemotherapy and Intensity-Modulated Radiation Therapy Guided by Combined CT and PET Imaging for Patients With Non-Small Cell Lung Cancer
Lung cancer is the leading cause of cancer-related mortality in the United States (US) and Canada. Because of the high incidence and mortality of this disease, small improvements in the management of this disease translates into…
- Trial name
- NCT00128999
- Testing
- Intensity-Modulated Radiation Therapy
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Alberta Health services
ADHD
A Novel fNIRS Neurofeedback Intervention for Enhancement of Working Memory in Attention Deficit Hyperactivity Disorder (ADHD)
The proposed study is to test and validate a novel intervention that integrates computerized cognitive training with real-time neuromonitoring and neurofeedback to enhance working memory by probing the individualized neural…
- Trial name
- NCT04002167
- Testing
- Neurofeedback, Cognitive training
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Stanford University
Brain and Central Nervous System Tumors
Motexafin Gadolinium With MRI-Guided Surgery in Treating Patients With High-Grade Gliomas
RATIONALE: New imaging procedures such as the use of gadolinium texaphyrin with MRI may improve the ability to detect the extent of gliomas.
- Trial name
- NCT00003410
- Testing
- motexafin gadolinium, magnetic resonance imaging, surgical procedure
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Laser Interstitial Thermal Therapy, Parkinson Disease
Possibilities of Use MRI-Guided Laser Interstitial Thermal Therapy in Medically Intractable Tremor
Medically intractable tremors are a common difficult clinical situation. Deep brain stimulation decreases Parkinson's disease tremor and essential tremor, but not all patients are candidates from a diagnostic, medical, or social…
- Conditions
- Laser Interstitial Thermal Therapy, Parkinson Disease, Essential Tremor, Movement Disorders
- Trial name
- PossibiLITT (NCT06799923)
- Testing
- laser electrode
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cardiac Arrhythmia
Use of "iSuite" During CMR-guided Electrophysiological Procedures
The perpuse of this study is to investigate the feasibility of the Philips interventional MRI suite "iSuite" to create an electroanatomical map of the heart based on which the real-time location of the catheters can be correctly…
- Trial name
- NCT04727645
- Testing
- Philips interventional MRI suite (Philips Healthcare, Best, the Netherlands)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Ziekenhuis Maastricht
Brain Neoplasms
Magnetic Resonance Imaging-Guided Laser Induced Thermal Therapy for Treatment of Metastatic Brain Tumors
In this study, the Visualase Thermal Therapy System will be used on metastatic brain tumors that cannot be removed by surgery. Researchers want to find out if it is possible to use this new device in subjects with 1-3 metastatic…
- Trial name
- NCT00787982
- Testing
- MRI-Guided Laser Induced Thermal Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Visualase, Inc.
Astrocytoma, Glioblastoma
Investigational Imaging Technique During Brain Surgery
This early phase I trial tests the safety and reliability of an investigational imaging technique called quantitative oblique back illumination microscopy (qOBM) during brain surgery for detecting brain tumors and brain tumor…
- Conditions
- Astrocytoma, Glioblastoma, Oligodendroglioma
- Trial name
- NCT05513859
- Testing
- Craniotomy, Quantitative Oblique Back-Illumination Microscopy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Lung Cancer
Real-Time Image Guided Lymphatic Mapping and Nodal Targeting in Lung Cancer
The primary purpose of this study is to determine if we can identify the first lymph node that drains from the tumor, and thus would be the most likely site for metastatic disease, and remove it for analysis to improve the…
- Trial name
- NCT00264602
- Testing
- Near Infrared Imaging
- Where
- 4 sites in United States
- Volunteers
- 57 people
- Sponsor
- Dana-Farber Cancer Institute
Endometriosis
Feasibility Study of Using Molecular Fluorescence Guided Surgery in Endometriosis
Incomplete resection of endometriosis lesions often results in recurrence of symptoms and the need for repeated surgery, with considerable associated morbidity.
- Trial name
- Endo-light (NCT02975219)
- Testing
- Bevacizumab-800CW
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- University Medical Center Groningen
NonST Elevation Myocardial Infarction
FAMOUS-NSTEMI MRI Sub-Study
BACKGROUND: Non-ST-segment elevation myocardial infarction (NSTEMI) is the commonest type of acute coronary syndrome (ACS) and has a poor long-term prognosis.
- Trial name
- NCT02073422
- Testing
- Fractional flow reserve, Magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- NHS National Waiting Times Centre Board
Papillary Thyroid Cancer, Lymph Node Metastases
Precision Thyroid Cancer Surgery With Molecular Fluorescent Guided Imaging
Almost 50 % of papillary thyroid cancer (PTC) patients have central lymph node metastases (CLNM), which are associated with a high risk of persistent or recurrent disease.
- Trial name
- TARGET (NCT03470259)
- Testing
- IV adminstration of EMI-137, Multispectral Fluorescence Reflectance Imaging, Spectroscopy
- Where
- 2 sites in Netherlands
- Volunteers
- 19 people
- Sponsor
- University Medical Center Groningen
Atrial Fibrillation (AF)
Personalized Atrial Fibrillation Ablation Guided by Non-Invasive Global Mapping
This pilot study investigates if non-invasive global mapping can guide catheter ablation of atrial fibrillation (AF) by defining personalized targets based on the temporal Stability of local Atrial High-Rate Activity (SAHRA).
- Trial name
- CURE-AF (NCT07320560)
- Testing
- Non-invasive mapping-guided ablation
- Where
- 5 sites in Germany, Portugal and 1 more
- Volunteers
- 45 people
- Sponsor
- German Heart Institute
Breast Cancer, Breast Cancer Invasive
Fluorescence Guided Surgery in Breast Cancer - The MARGIN-2 Study
The goal of this clinical trial is to intraoperatively visualize tumour tissue in breast cancer patients using fluorescence imaging with the tracer bevacizumab-IRDye800CW and thereby enhance real-time clinical decision making…
- Trial name
- MARGIN-2 (NCT05939310)
- Testing
- Fluorescence guided detection of tumor positive margins.
- Where
- 2 sites in Netherlands
- Volunteers
- 70 people
- Sponsor
- University Medical Center Groningen
Cervical Cancer
An International Study on Magnetic Resonance Imaging (MRI)-Guided Brachytherapy in Locally Advanced Cervical Cancer
Background: The standard treatment of locally advanced cervical cancer is radio-chemotherapy including external beam radiotherapy (EBRT), brachytherapy (BT) and concomitant chemotherapy with weekly Cisplatin.
- Trial name
- EMBRACE (NCT00920920)
- Testing
- 3D MRI-guided Brachytherapy
- Where
- Austria
- Volunteers
- 1,416 people
- Sponsor
- Medical University of Vienna
Coronary Artery Calcification, Coronary Artery Disease
Intravascular Imaging-Guided Intravascular Lithotripsy for Severe Coronary Calcified Lesions.
This study aims to investigate the efficacy and safety of intravascular lithotripsy (IVL) balloon in treating coronary calcified lesions at our center.
- Trial name
- NCT07444346
- Testing
- percutaneous coronary intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University