Clinical trials: Immediate Effect
Allergic Rhinitis
The Effect of Omalizumab on Allergic Rhinitis Symptoms: a Comparative Study
We aimed to evaluate the usability and efficacy of omalizumab in allergic rhinitis and its potential as an alternative treatment option.
- Trial name
- rhinitis (NCT06806826)
- Testing
- Omalizumab
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Yuzuncu Yil University
Asthma, Airway Obstruction
Single-dose Crossover Study to Investigate Pharmacodynamics of AZD3199
The purpose of this study is to investigate the pharmacodynamics of single doses of AZD3199 in asthmatic patients.
- Trial name
- NCT00736489
- Testing
- AZD3199, Formoterol
- Where
- 4 sites in Denmark, Sweden
- Volunteers
- 37 people
- Sponsor
- AstraZeneca
Asthma
Effects of Liuzijue Exercise Versus Tai Chi Chuan Exercise in Asthma
To analyze either Liuzijue exercise or Tai Chi Chuan exercise is effective in improving dyspnea index and pulmonary function in patients with asthma.
- Trial name
- NCT06426849
- Testing
- Liuzijue Exercise, Tai Chi Chuan Exercise
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Asthma
Breathing & Mild Physical Exercise Therapy for Asthma
Overall goal: To apply the investigators' well defined simple, few-minute breathing/ mild physical exercise program and evaluate its efficacy/benefits for the improvement of clinico-immunological outcome in obese patients with…
- Trial name
- NCT01509443
- Testing
- Exercise
- Where
- Kuwait
- Volunteers
- 100 people
- Sponsor
- Dasman Diabetes Institute
Delayed Onset Muscle Soreness (DOMS), Inflammation
Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion
The goal of this clinical trial is to learn if applying cold therapy can reduce swelling, inflammation, and pain after physical activity in adults who experience muscle soreness (Delayed Onset Muscle Soreness, or DOMS).
- Conditions
- Delayed Onset Muscle Soreness (DOMS), Inflammation, Muscle Pain, Muscle Damage
- Trial name
- NCT06813690
- Testing
- Cold Therapy with Axanova Cold Hot Pearls Maxi Pack
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Pes Planus
Immediate Effects of Kinesio Taping and Manual Release in Young Adults With Pes Planus
Pes planus is a postural deformity seen with decreased medial longitudinal arch (MLA) height and this causes intense stress on the plantar fascia.
- Trial name
- NCT05296850
- Testing
- Manual Release, Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara Yildirim Beyazıt University
Asthma, GERD
Safety and Efficacy Study to Determine Anti-Asthmatic Effect of Esomeprazole Magnesium; Nexium Reflux Asthma
The purpose of this study is to determine whether treatment with esomeprazole for 6 months will improve asthma in adult patients with moderate to severe asthma and symptoms of gastroesophageal reflux disease.
- Trial name
- RELAX (NCT00317044)
- Testing
- Esomeprazole
- Where
- 130 sites in United States, Argentina and 12 more
- Volunteers
- 961 people
- Sponsor
- AstraZeneca
Cow's Milk Allergy, Atopic Disease
Effect Of Lactobacillus GG on Atopic March
Food allergy (FA), defined as an adverse immune response to food allergens, is among the most frequent allergic disorders in childhood and it has recognized as a major paediatric health problem due to the severity of the…
- Trial name
- NCT01891916
- Testing
- Extensively hydrolyzed casein formula + LGG
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Federico II University
Asthma, Chest Syndrome
Azithromycin Treatment for Non-eosinophilic Chest Tightness Variant Asthma
Bronchial asthma (abbr. asthma) is one of common airway chronic inflammatory disease which usually threatens human health. Typical symptoms of asthma are recurrent wheezing, shortness of breath, chest tightness and cough, usually…
- Conditions
- Asthma, Chest Syndrome, Azithromycin, Effect of Drug
- Trial name
- NCT05596721
- Testing
- Azithromycin, ICS/LABA
- Where
- 13 sites in China
- Volunteers
- 248 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Subacromial Impingement, Subacromial Impingement Syndrome
Thoracic Spine Thrust Manipulation Compared to Sham Manipulation in Individuals With Subacromial Pain Syndrome
This study evaluates the immediate and short-term effects of a supine upper thoracic spine thrust manipulation, seated upper thoracic spine thrust manipulation, and sham manipulation for individuals with subacromial pain…
- Trial name
- NCT03109704
- Testing
- Supine upper thoracic spine thrust manipulation, Seated upper thoracic spine thrust manipulation
- Volunteers
- 60 people
- Sponsor
- Sacred Heart University
Perennial Allergic Rhinitis
Effects of Pine Cone Extract on Serum IgE Levels in Perennial Rhinitis
The medicinal properties of pinecones have been used for years to treat a variety of illnesses. In the mouse model, an extract of pine cones, poly-phenylpropanoid-polysaccharide complex (PPC), has been shown to reduce total serum…
- Trial name
- PCE (NCT04024033)
- Testing
- pine cone extract
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of South Florida
Rheumatoid Arthritis, Healthy Volunteers
A Study in Normal Healthy People, Testing Different Versions of a Pill That Will be Used to Treat Rheumatoid Arthritis.
The study will try, in 2 separate parts, each using 12 research subjects, to see how a new form of the pill CE 224,535 gets released into the bloodstream and whether that is affected by food.
- Trial name
- NCT00838058
- Testing
- CE-224,535, CE 224,535
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Pfizer
Chronic Spontaneous Urticaria (CSU)
Effects of Diet and Oxidative Stress on Disease Severity and Response to Omalizumab in Chronic Spontaneous Urticaria
Chronic spontaneous urticaria (CSU) is an immune-mediated skin disorder characterized by pruritic wheals and/or angioedema. This study aims to evaluate the relationship between diet-derived antioxidant capacity and oxidative…
- Trial name
- NCT07431658
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Stroke
Applicability of Techniques of Lung Expansion
The survival of patients with lesions in the central nervous system is usually accompanied by physical and mental sequelae. These impairments favor the prolonged restriction to the bed, which may contribute with changes in…
- Trial name
- NCT02613832
- Testing
- EPAP, Breath Stacking
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Persistent Allergic Asthma
Evaluate the Effect of Omalizumab on Markers of Asthma Impairment in Patients With Persistent Allergic Asthma
This study will evaluate the effect of omalizumab on markers of impairment in patients with inadequately controlled persistent allergic asthma on Step 4 or above therapy as defined in the 2007 National Heart, Lung, and Blood…
- Trial name
- NCT00870584
- Testing
- Omalizumab
- Where
- 50 sites in United States
- Volunteers
- 271 people
- Sponsor
- Novartis Pharmaceuticals
Asthma, Distal Lung Inflammation
Mentored Patient-Oriented Research Career Development Award
Asthmatics have inflammation in the large airways (tubes through which air travels in and out of the lungs). The large airways are located in the central lung.
- Trial name
- NCT00203684
- Testing
- Flunisolide-HFA, Flunisolide-CFC
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Asthma
Dose Ranging Efficacy And Safety With Mepolizumab in Severe Asthma
The purpose of this study is to show whether mepolizumab given every 4 weeks intravenously (i.v.) can reduce the frequency of asthma exacerbations in subjects with severe asthma despite receiving high doses of standard asthma…
- Trial name
- DREAM (NCT01000506)
- Testing
- Mepolizumab 750, Mepolizumab 250, Mepolizumab 75
- Where
- 94 sites in United States, Argentina and 11 more
- Volunteers
- 621 people
- Sponsor
- GlaxoSmithKline
Acute Allergic Reaction, Anaphylaxis
Phase 1 Crossover Study Evaluating the Safety, Tolerability, and Pharmacokinetics of KP001 in Healthy Adult Volunteers
The goal of this clinical trial is to evaluate the safety, tolerability, and pharmacokinetics (PK) of several KP001 dose regimens to identify a treatment regimen with a PK profile that safely meets or exceeds the PK profile of…
- Trial name
- NCT06963411
- Testing
- KP001
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kokua Pharma Inc.
Post-Concussive Syndrome, Chronic
The Immediate Effects of Dry Needling on Post-concussion Syndrome
In about 15% of adult concussion cases, symptoms last longer than 2 weeks and can largely impact the individual's ability to work, be physically active and participate in everyday life.
- Trial name
- NCT03949998
- Testing
- Dry Needling, Manual Therapy
- Where
- 3 sites in Canada
- Sponsor
- University of Guelph
Healthy
Comparison of Muscle Energy Technique vs Static Stretch in Vertical Jump of Basketball and Volleyball Player
A randomized control trial study was conducted in Islamic International University Islamabad from 1st August 2017 to 31st January 2018 according to the set criteria.
- Trial name
- NCT04002206
- Testing
- Muscle Energy Technique, Static Stretch
- Where
- Pakistan
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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