Clinical trials: Impact on Patients
Atopic Dermatitis With a History of Eczema Herpeticum, Atopic Dermatitis Without a History of Eczema Herpeticum
Impact of Increased Immunoglobulin E to Anti-herpes Simplex Virus -1 Innate Immune Responses in Atopic Dermatitis Patients With Eczema Herpeticum
This study investigates whether blood monocytes' surface bound- immunoglobulin E affects the innate immune responses against herpes simplex viruses in atopic dermatitis patients with eczema herpeticum.
- Conditions
- Atopic Dermatitis With a History of Eczema Herpeticum, Atopic Dermatitis Without a History of Eczema Herpeticum, Health Controls Without Atopy
- Trial name
- NCT04060550
- Testing
- Xolair
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Efficacy of DHEA, Pregnancy Rate
Administration of DHEA in Patients With Poor Response to Ovarian Stimulation for IVF
Poor responders to ovarian stimulation represents one of the most frustrating problems in reproductive medicine. The investigators hypothesize that ovarian response of those patients could improve by treating these patients with…
- Conditions
- Efficacy of DHEA, Pregnancy Rate, Diminished Ovarian Reserve, Changes in AMH
- Trial name
- DHEA (NCT02099916)
- Testing
- gonadotropins plus DHEA, Gonadotropins
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Athens
Axial Spondyloarthritis, Central Sensitisation
Investigation of Central Sensitization Frequency and Related Factors in Axial Spondyloarthritis Patients
The term axial spondyloarthritis (axSpA) describes a group of chronic inflammatory diseases that characterized with spinal involvement.
- Trial name
- NCT04485078
- Testing
- Pressure pain threshold, Temporal summation, Conditioned pain modulation
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Marmara University
Postoperative Depression
The Impact of Preoperative Chronic Pain on Postoperative Depressive States in Elderly Patients Undergoing Joint Replacement Surgery: A Secondary Analysis Based on Prospective Data
Background: Postoperative depression is a significant complication that hinders recovery in elderly patients undergoing joint replacement surgery.
- Trial name
- NCT07403838
- Where
- China
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Psychosocial Problem, Problematic Behavior in Children
Triple P With Pediatric Residents
The objective of this study is to conduct a randomized control trial to evaluate the impact of Triple P on the clinic practice of pediatric residents and on select parent and child outcomes.
- Conditions
- Psychosocial Problem, Problematic Behavior in Children, Parenting
- Trial name
- NCT01946958
- Testing
- Training in PC Triple P, Care As Usual
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Skin
Metabolomic Evaluation of the Impact of Acqua Rocchetta on the Skin of Healthy Patients.
Evaluation of changes in skin metabolism after one month of intake of Acqua Rocchetta (water A) vs bicarbonate-calcic mediomineral water (water B) (reprogramming effect on skin metabolism); Evaluation of urinary profiles after…
- Trial name
- NCT05033795
- Testing
- Water A, Water B
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Irriversible Pulpitis
Analyzing the Impact of Occlusal Reduction on the Pain Following Root Canal Therapy in Molar Teeth With and Without Pain in Turkish Patients.
Introduction: This study aimed to compare the intensity of postoperative pain after single-visit root canal treatment of symptomatic or asymptomatic teeth following occlusal reduction.
- Trial name
- NCT06953856
- Testing
- occlusal reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Tooth Mobility, Periodontitis
Impact of MINST With and Without Splinting in Periodontitis Patients With Mobile Anterior Teeth
The goal of this clinical trial is to evaluate impact of Minimally Invasive Non-Surgical Therapy (MINST) with and without splinting on clinical periodontal parameters and Oral Health Related Quality of Life (OHRQoL) in…
- Trial name
- NCT06436729
- Testing
- Splinting, MINST alone
- Where
- India
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Coronary Artery Disease (CAD), Cardiac Rehab
The Effect of Cardiac Rehabilitation on Ferroptosis in Patients With Coronary Artery Disease
Coronary artery disease (CAD) remains a major global health concern and is the leading cause of cardiovascular mortality worldwide.
- Conditions
- Coronary Artery Disease (CAD), Cardiac Rehab, Ferroptosis
- Trial name
- NCT07722637
- Testing
- Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Hypertension, Diabete Type 2
Pharmacists Interventions on Patients Diabetic, and Obese Patients in the UAE: Randomized Controlled Trials.
Hypertension, diabetes, and obesity are considered major risk factors for cardiovascular diseases and premature mortality worldwide. Furthermore, they have severe consequences on quality of life among patients.
- Conditions
- Hypertension, Diabete Type 2, Obesity, Pharmacist-Patient Relations
- Trial name
- NCT05488002
- Testing
- Pharmaceutical intervention
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease (NAFLD)
The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
The goal of this clinical trial is to learn if daily supplementation with Low-methoxy (LM) pectin (polysaccharides extracted from citrus peels), which are commonly found in the UK diet (not pharmacological agents), can reduce…
- Conditions
- Nonalcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease (NAFLD), MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, MASLD
- Trial name
- PEC-MASLD (NCT07093346)
- Testing
- Pectin, Cocoa Powder, Magnetic Resonance Imaging with Contrast
- Where
- 3 sites in United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Heart Failure, Cardiac Failure
Impact of the Aerobic Exercise Versus Exercise of Force on the Hemodynamic, Lipidic, Anthropometric and Psychological Variables of Patients With Cardiac Failure
Introduction and objectives: At the global level, cardiovascular diseases are the leading cause of mortality. Currently, rehabilitation programs are shown as an effective treatment to mitigate the effects of heart failure.
- Trial name
- NCT03913780
- Testing
- Aerobic exercise more force
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- University Tolteca
Impacted Third Molar Tooth
the Relationship Between Various Clinical Variables and Surgical Difficulty of Patients Have Impacted Lower Third Molar
This study is to evaluate the effect of angle of impaction, impaction depth, and bone density on surgical difficulty of impacted lower third molar, by measuring the angle of impaction, the depth of impaction (Winter's Red line)…
- Trial name
- NCT05320744
- Testing
- surgical extraction of impacted lower third molar
- Where
- Iraq
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Breast Cancer
Evaluating the Impact of Evidence-based Information About Mammography on Breast Cancer Screening Decisions
Patient decision aids are tools that help guide individuals through a healthcare-related decision making process. They help users combine evidence-based information and recommendations by a health care provider with their…
- Trial name
- NCT03631758
- Testing
- Evidence-based information, Patient Decision Aid
- Where
- Canada
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- McMaster University
Agitation Management, Aggression
Effect of Verbal De-Escalation-Based Simulation on Agitation Management, Perception of Aggression, and Impact of Aggression in Emergency Department Nurses
This mixed-methods randomized controlled study aims to evaluate the effects of verbal de-escalation-based simulation training on emergency department nurses' knowledge of agitation management, perceptions of aggression, and the…
- Conditions
- Agitation Management, Aggression, Verbal De-Escalation
- Trial name
- NCT07784868
- Testing
- Standard Verbal De-Escalation Training, Verbal De-Escalation-Based Simulation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Laxity; Skin
Assess Impact of Poly-L-lactic Acid on GLP1 Subjects
Clinical trial to evaluate treatments of double-dilute poly-L-lactic acid on abdominal skin laxity in GLP1 patients versus non GLP1 patients.
- Trial name
- NCT07217743
- Testing
- Sculptra Aesthetic
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Bariatric Surgery Candidate
Impact Of Post-Bariatric Body Contouring Procedures on Patient Body Weight and Metabolism
Is post-bariatric body contouring surgery prevent weight regain or no, and what is the effect on the patient's Metabolism? Few literature studies report body contouring surgery to be positively associated with maintained weight…
- Trial name
- NCT05034081
- Testing
- body contouring
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cellulitis
A Study Assessing the Impact of Dermatology Consultation in Patients Presenting With Possible Cellulitis
This is a randomized, controlled study to compare patients evaluated by primary care physicians alone versus patients who are additionally evaluated by a dermatologist at the primary care physician"s office, aiming to demonstrate…
- Trial name
- NCT01795092
- Testing
- Dermatology Consultation
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Edentulous Mouth, Quality of Life
Impact of Retro-molar Pad Demarcation on Complete Denture Wearers' Satisfaction
the retromolar pad is a critical anatomical landmark in the lower edentulous arch marking the posterior end of any removable prosthesis.
- Conditions
- Edentulous Mouth, Quality of Life, Patient Satisfaction, Complete Edentulism
- Trial name
- RMP (NCT07246343)
- Testing
- carving of retromolar pad area (RMP), no carving of the retromolar pad area (RMP)
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samiha Sartawi
Prosthesis Durability
Impact of Mandibular Overdenture Base Construction Techniques on Assessment of Occlusion
This within patient study will be conducted to compare between two different construction techniques (CAD-CAM Milled and Conventional techniques) of 4-implant-assisted complete mandibular overdenture bases regarding the digital…
- Trial name
- NCT06080815
- Testing
- CAD/CAM Complete denture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University