Clinical trials: Implant Infection
Gingivitis
Clinical Study to Investigate a New Mouthwash in Reducing Plaque and Helping Prevent Gum Problems on Dental Implants Over a 6-month Period of Product Use
The objective of this six-month clinical research study is to evaluate the clinical efficacy of a new mouthwash on helping prevent gum problems (gingival index scores ) in adults as compared to a control mouthwash.
- Trial name
- NCT06770114
- Testing
- Cetylpyridinium Chloride, Zinc Lactate and Hyaluronic Acid Mouthwash, PhosFlur Mouthwash
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Penile Implantation, Infections
Next Generation Sequencing Versus Traditional Cultures for Clinically Infected Penile Implants: Impact of Culture Identification on Outcomes
Randomized prospective study to evaluate next generation sequencing (NGS) and standard-of-care culture for clinically infected penile implants and to compare outcomes with identification of microbes.
- Trial name
- NCT05287438
- Testing
- Next-Generation DNA Sequencing, Standard Culture
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- MicroGenDX
Dislocation, Infection
Fixation of Thoracic Epidurals Influencing Catheter-related Infections and Dislocation
Major interest in our investigation is to find out whether distinct fixation techniques influence catheter dislocation and/ or incidence of local inflammation.
- Conditions
- Dislocation, Infection, Line Colonisation, Line Insertion Site
- Trial name
- TDPAFD (NCT01402778)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Implant Complication, Implant Infection
Local Antibiotics for Breast Implants
The BREAST-AB Trial is a multi-center, randomized, double blind, placebo-controlled trial investigating the efficacy of local application of gentamicin, vancomycin and cefazolin in decreasing all-cause implant explantation after…
- Conditions
- Implant Complication, Implant Infection, Implant Site Infection, Implant Capsular Contracture
- Trial name
- BREAST-AB (NCT04731025)
- Testing
- Gentamicin, Cefazolin and Vancomycin
- Where
- 8 sites in Denmark
- Volunteers
- 1,003 people, healthy volunteers welcome
- Sponsor
- Mikkel Herly
Implant Infection, Bone Loss
The Effect of Chlorohexidine Gel on Tissue Healing Following Surgical Exposure of Dental Implants
The aim of this study is to evaluate the healing of peri-implat tissue following surgical uncovering with the adjunctive use of Chlorohexidine (CHX) gel.
- Trial name
- NCT03195582
- Testing
- Corsodyl
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Surgical Site Infection (SSI)
A Randomized Controlled Trial Comparing the Incidence of Surgical Site Infections in Cesarean Section With and Without Subcutaneous Drain Placement at Queen Savang Vadhana Memorial Hospital
To study and compare the incidence of surgical site infection after cesarean section in pregnant women with subcutaneous wound drainage and those without subcutaneous wound drainage at Queen Savang Vadhana Memorial Hospital…
- Trial name
- NCT07395518
- Testing
- Radivac drain
- Where
- Thailand
- Volunteers
- 86 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
PICC Line Placement
COMPLI-PICC: Study on Picclines' Complications
This is a prospective monocentric study of PICC Line complications use in 5 medical and one surgical units of Brest Medical University Hospital.
- Trial name
- COMPLI-PICC (NCT03017911)
- Testing
- Piccline
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Brest
Postoperative Infection
Post-operative Antibiotics; Effects on Risk of Infection After Cochlear Implant Surgery
Currently there is little consensus regarding postoperative antibiotic prophylactic treatment and its effect on the postoperative infection rate after Cochlear implantation.
- Trial name
- NCT06177444
- Testing
- Antibiotic
- Where
- Denmark
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cancer, Infection
Primary Prevention of Infections Related to Chambers Implantable Catheter by a Taurolodine Lock in Patients With Cancer Receiving Parenteral Nutrition
The therapeutic management of patients with cancer often requires the establishment of a chamber implantable catheter. Infections are the main complication of these catheters.
- Trial name
- NCT02255318
- Testing
- Taurolock
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Empyema, Pleural
VATS Decortication Versus IR Guided Chest Tube Insertion With Fibrinolytics for the Management of Empyema
The American Association of Thoracic Surgery defines empyema as pus in the pleural space. It is a common thoracic surgery presentation with an estimated 65,000 cases occurring annually in the United States.
- Trial name
- DICE (NCT03584113)
- Testing
- Video assisted thorascopic decortication, Interventional radiology guided chest tube insertion with MIST2 trial fibrinolytics
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Dr. Wiley Chung
Dental Implant Failed, Bone Fracture
Alveolar Ridges Expansion Using Osseodensification Versus Screw Expansion Technique
Alveolar ridge expansion is suggested for alveolar crest thicknesses of 3-5 mm. Osseodensification (OD) and screw expansion (SE) techniques have been utilized to expand narrow alveolar ridges (NAR).
- Conditions
- Dental Implant Failed, Bone Fracture, Bone Infection
- Trial name
- NCT05895903
- Testing
- Screw expander, Osseodensification drills
- Where
- Iraq
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pediatric Cancer, Pediatric Oncology
Central Venous Catheter Care Training for Pediatric Oncology Nurses
The knowledge level of nurses regarding care techniques plays a crucial role in the prevention of central venous catheter-related infections.
- Conditions
- Pediatric Cancer, Pediatric Oncology, Central Venous Catheter, Central Venous Catheter Placement
- Trial name
- NCT07345598
- Testing
- CVC Care Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Bacterial Infection, Anti-infective Agents
Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction
Antibiotics are used routinely in postoperative tissue expander based breast reconstruction (TE) and autologous flap (AF) breast reconstruction procedures.
- Conditions
- Bacterial Infection, Anti-infective Agents, Breast Implantation
- Trial name
- NCT01244698
- Testing
- Cefadroxil discontinued early, Cefadroxil until drain removal
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Implant Infection, Alveolar Bone Loss
Associations of Alveolar Bone Loss and Interleukin-1β Levels in One and Two Stage Surgical Procedures
The present study was compared the level of alveolar bone loss, clinical parameters and IL-1β in PICF in one- or two-stage surgical procedures.
- Trial name
- NCT03045458
- Testing
- tissue level dental implant, Bone level dental implant
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Firat University
Surgical Wound Infection
Local Gentamicin Application to Reduce Postoperative Infection Rate
The majority of elderly patients with a displaced fracture of the proximal femur are now treated with a hemiarthroplasty. Prosthetic joint infection is a devastating complication, and the infection rate is high in this group of…
- Trial name
- NCT01287780
- Testing
- Collagen-gentamicin sponge
- Where
- 5 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Oslo University Hospital
Chagas Cardiomyopathy, Non-sustained Ventricular Tachycardia
Amiodarone Against ICD Therapy in Chagas Cardiomyopathy for Primary Prevention of Death
The primary objective is to compare the efficacy of the treatment using implantable cardioverter defibrillator (ICD) implantation to that of the treatment using amiodarone in the primary prevention of all-cause mortality in…
- Conditions
- Chagas Cardiomyopathy, Non-sustained Ventricular Tachycardia, At Least 10 Points in Rassi Risk Score for Death
- Trial name
- CHAGASICS (NCT01722942)
- Testing
- ICD implantation, amiodarone hydrochloride
- Where
- 20 sites in Brazil
- Volunteers
- 1,100 people
- Sponsor
- InCor Heart Institute
Infections of the Implanted Material, Endocarditis
Diagnostic Accuracy of 18FDG-PET-CT for Pacing or Defibrillation Lead Infection
With aging of the general population and broadening indications, the number of pacemaker recipients is steadily increasing. The incidence of infections of the implanted material, a dreaded major complication, is also rising.
- Trial name
- ENDOTEP (NCT02251262)
- Testing
- Whole-body 18FDG-PET-CT scan
- Where
- 6 sites in France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Bordeaux
Cardiac Implantable Electronic Device Infection
Taurolidine Containing Antimicrobial CIED Wash to Prevent Infection
From January 1st 2020, any CIED procedure conducted with adjunct TauroPace™ CIED and pocket irrigation is enrolled in a consecutive manner and followed up in one centre. Follow-up is prospectively.
- Trial name
- NCT05576194
- Testing
- TauroPace, Hydrogen Peroxide, Taurolidine
- Where
- Germany
- Volunteers
- 1,417 people
- Sponsor
- Prof. Dr. Hendrik Bonnemeier
Bronchiolitis
Placement of Nasogastric Tubes for Gastric Decompression in Patients With Bronchiolitis
This study aims to evaluate whether placing nasogastric tubes for gastric decompression improves respiratory distress for patients with bronchiolitis who are receiving oxygen via high-flow nasal cannula.
- Trial name
- NCT04480970
- Testing
- Nasogastric tube placement
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Coronary Disease, Heart Valve Diseases
CTI-01 (Ethyl Pyruvate) Safety and Complication Prevention in Cardiac Surgery Patients on Cardiopulmonary Bypass (CPB)
Over 500,000 patients undergo cardiac surgery with CPB in the United States annually. Although mortality rates have decreased with advances in perioperative care, many patients are affected by postoperative organ dysfunction.
- Trial name
- NCT00107666
- Testing
- CTI-01 (ethyl pyruvate)
- Where
- 17 sites in United States
- Volunteers
- 150 people
- Sponsor
- Critical Therapeutics