Clinical trials: Implants
Immediate Implants
Connective Tissue Graft Versus a Porcine-derived Membrane (Mucoderm) After Immediate Placement
Esthetic outcome of immediate implant placement in fresh extraction sockets remains one of the biggest challenges in implant dentistry.
- Trial name
- NCT04737525
- Testing
- Dental implant placement, bone and soft tissue augmentation on buccal site
- Where
- Lithuania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Vilniaus Implantologijos Centro (VIC) Klinika
Cardiomyopathy, Dilated, 3B
CRT-P or CRT-D in Dilated Cardiomyopathy
The ICD-Reality study is a non-commercial, investigator-led, multicenter, prospective, randomized, controlled trial. We aim to determine the effect of CRT-D or CRT-P implantation in non-ischemic cardiomyopathy and heart failure…
- Trial name
- CRT-REALITY (NCT04139460)
- Testing
- CRT-D, CRT-P
- Where
- Czechia
- Volunteers
- 924 people
- Sponsor
- University Hospital Olomouc
Alveolar Bone Loss, Dental Implant
Magnetic Mallet Vs Conventional Drilling in D4 Posterior Maxilla
The goal of this clinical trial is to evaluate whether the magnetic mallet technique improves primary implant stability and clinical outcomes compared with conventional drilling during dental implant placement in the posterior…
- Conditions
- Alveolar Bone Loss, Dental Implant, Osseodensification Drilling Technique
- Trial name
- NCT07424820
- Testing
- Conventional drilling osteotomy, Magnetic mallet osteotomy
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Mosul
Arrhythmia Prophylaxis, Ventricular Arrhythmia
Dose Ranging Study of Celivarone With Amiodarone as Calibrator for the Prevention of Implantable Cardioverter Defibrillator (ICD) Interventions or Death
The Primary objective was to assess the efficacy of Celivarone for the prevention of Implantable Cardioverter Defibrillator (ICD) interventions or death.
- Trial name
- ALPHEE (NCT00993382)
- Testing
- Celivarone, Amiodarone
- Where
- 151 sites in United States, Argentina and 24 more
- Volunteers
- 486 people
- Sponsor
- Sanofi
Breast Reconstruction
Pulsed Lavage in Implant-Based Breast Reconstruction
To determine if there is any benefit to using pulsed lavage to wash out the mastectomy pocket during breast reconstruction. Primary outcomes will include post-op complications including surgical site infection (SSI), hematoma…
- Trial name
- NCT05585710
- Testing
- Pulsed Lavage Washout, Implant-based breast reconstruction, Bilateral or unilateral mastectomy
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Alabama at Birmingham
Spinal Accessory Nerve Injury, Cervical Lymphadenopathy
Do AxoGuard Implants Decrease Shoulder Disability After Neck Dissections
The purpose of this study is to determine whether Axoguard nerve protectors have a role in preventing shoulder disability and pain following spinal accessory nerve sparing neck dissections.
- Trial name
- NCT03941327
- Testing
- AxoGuard Nerve Cuff
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Mississippi Medical Center
Hearing Loss, Sensorineural, Cochlear Implant
MED-EL Remote Care Multi-Center Feasibility Study
MED-EL Remote Care is a way for MED-EL cochlear implant users to check their hearing and cochlear implant device from any location, without the need for a scheduled, in-person appointment with their audiologist.
- Conditions
- Hearing Loss, Sensorineural, Cochlear Implant, Cochlear Implant Recipients, Hearing Disorders
- Trial name
- NCT05973669
- Testing
- MED-EL Remote Care
- Where
- 5 sites in United States, Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Med-El Corporation
Atrial Fibrillation
Apixaban in Patients Who Undergo CIED Procedure- Randomized Pilot Study
This study is being done to determine if apixaban is more safe, when compared to warfarin, at reducing the risk of bleeding during CIED procedures.
- Trial name
- Apixaban (NCT02450682)
- Testing
- Apixaban, Warfarin
- Where
- United States
- Sponsor
- Mayo Clinic
Osteoarthritis, Knee
TKA Operating Room Efficiency for TKA Using Customized Implant Techniques
This is a multi-centered prospective, consecutively enrolled study that will be conducted in the United States. Surgeons that are new users of the iTotal Knee system (defined by no experience using the customized Total Knee…
- Trial name
- NCT04180423
- Testing
- Off-the-Shelf Implant Total Knee Replacement, Customized Implant Total Knee Replacement
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Restor3D
Cystic Fibrosis
Study About Complications of Totally Implanted Venous Access Devices (TIVADs) in People With Cystic Fibrosis (CF)
Pulmonary infections are the major cause of mortality and morbidity in cystic fibrosis (CF); patients frequently have to take antibiotics which often cannot be given orally or by aerosol but have to be administered intravenously.
- Trial name
- NCT00670579
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Florence
GERD
Multi-Center Study of the NDO Surgical Plicator Utilizing Multiple Implants for the Treatment of GERD
The purpose of this study was to evaluate the safety and efficacy of placing multiple transmural sutures for the treatment of GERD.
- Trial name
- NCT00586859
- Testing
- NDO Full-thickness Plicator
- Where
- 4 sites in Germany
- Volunteers
- 41 people
- Sponsor
- NDO Surgical, Inc.
Implantable Cardioverter-defibrillators (ICDs)
Nursing Intervention Guided by an ICD Nursing Guideline
This study aimed to evaluate evidence-based nursing intervention guided by an ICD nursing guideline on self-efficacy, device acceptance, satisfaction with nursing care, and outcome expectations among ICD candidates during the…
- Trial name
- NCT07449559
- Testing
- nursing care with an evidence-based ICD nursing guideline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Deafness; Perception, Bilateral
Feasibility of Remote Cochlear Implant Users' Follow-up
Cochlear implants (CIs) are medical devices now widely used in persons with severe to profound hearing loss. After a six month to one-year period following implantation, adults typically reach optimal fitting parameters, which…
- Trial name
- TELERIC1 (NCT03022227)
- Testing
- telemedicine
- Volunteers
- 30 people
- Sponsor
- Hôpital Rothschild
Sensorineural Hearing Loss, Bilateral Hearing Loss
Comparative Analysis of Hearing Outcomes: Robotic vs. Manual Insertion of Cochlear Implants
This research study is evaluating two different methods of cochlear implant (CI) insertion - robotic-assisted insertion and manual insertion - to better understand how they affect hearing outcomes.
- Conditions
- Sensorineural Hearing Loss, Bilateral Hearing Loss, Cochlear Implantation, Hearing Disorders
- Trial name
- NCT07081542
- Testing
- IotaSoft Robotic Insertion System, Manual Cochlear Implant Insertion
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- AdventHealth
Atrophic Mandible
Two Types of PRF Membranes in Management of Dehiscence Defect in Posterior Mandible
Background: Placement of implants in an atrophic posterior ridge is a challenge for so many clinicians. The success of dental implants depends on the volume of alveolar bone available to provide stability.
- Trial name
- NCT07164417
- Testing
- e-PRF membrane will be used with xenograft simultaneously with implant placement., PRF membrane will be used with xenograft simultaneously with implant placement
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hip Arthritis
Digital Sizing for Orthopaedic Hip Implants
Hip implants come in different sizes. Currently, surgeons predict the implant size that will be needed using an analogue method whereby photos of the implant sizes are overlaid on the x-rays.
- Trial name
- NCT00665210
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ottawa Hospital Research Institute
Alveolar Bone Loss, Socket Shield Technique
Socket Shield Technique With CGF and Xenograft for Immediate Implants
This prospective case series aims to evaluate the clinical and radiographic outcomes of immediate implant placement using the socket shield technique combined with concentrated growth factors (CGF) and xenograft in the esthetic…
- Conditions
- Alveolar Bone Loss, Socket Shield Technique, Bone Resorption, Immediate Dental Implant Placement
- Trial name
- CGF (NCT07520513)
- Testing
- Socket Shield Technique with Immediate Implant Placement and CGF + Xenograft
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Cairo University
Angle Class II
Maxillary Molar Distalization Supported by Mini-implants With the Advanced Molar Distalization Appliance (Amda®)
The aim of this randomized controlled clinical trial is to evaluate the dentoalveolar and skeletal treatment effects of the AMDA when used for distalization of the maxillary first molars in patients with Class II malocclusion in…
- Trial name
- NCT06011382
- Testing
- Advanced Molar Distalization Appliance (amda®), Buccal mini-implants
- Where
- Romania
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Cochlear Implant Recipients, Hearing Loss, Cochlear
An Investigation to Evaluate Sound Coding Enhancements in Adult Cochlear Implant Recipients
This study will evaluate a range of experimental sound coding strategies that may improve hearing for cochlear implant recipients.
- Trial name
- SONORA-MU (NCT06867380)
- Testing
- Investigational sound coding strategy A, Cochlear default sound coding strategy A, Investigational sound coding strategy B
- Where
- 2 sites in Australia
- Volunteers
- 120 people
- Sponsor
- Cochlear
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