Clinical trials: Implants
Arrhythmia, Quality of Life
Magnesium to Reduce Implantable Cardioverter Defibrillator (ICD) Shocks and Improve Patient's Quality of Life.
This study is being conducted to see if magnesium can reduce the number of shocks patients with ICDs experience and to see if magnesium supplementation improves patients quality of life.
- Conditions
- Arrhythmia, Quality of Life, Hypomagnesemia
- Trial name
- NCT00282620
- Testing
- Magnesium L-lactate
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Hartford Hospital
Parkinson Disease, Epilepsy
Neurofeedback Using Implanted Deep Brain Stimulation Electrodes
Deep brain stimulation (DBS) has become a gold-standard symptomatic treatment option for Parkinson's disease (PD) and is also explored for a variety of other neurological disorders.
- Conditions
- Parkinson Disease, Epilepsy, Essential Tremor
- Trial name
- NCT05101161
- Testing
- Neurofeedback
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- ETH Zurich
Bruxism
Which is More Effective in Management of Bruxism: Botox or Occlusal Splints
The aim of this study is to compare the efficacy of Botulinum toxin (Botox) and traditional occlusal splints for the management of bruxism in edentulous patients rehabilitated with MIOD
- Trial name
- NCT04366869
- Testing
- overdenture, occlusal splint, Botox
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Attachment Disorder, Stress Disorder
Wear Assessment of Novel PEEK Telescopic Attachment for Overdenture
To assess the wear of Zirconia-PEEK versus cobalt-chromium-PEEK telescopic attachments for implant retained complete mandibular overdenture.
- Trial name
- NCT06434142
- Testing
- implant overdenture
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hamada Zaki Mahross Atia
Atrial Fibrillation, Stroke
Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation
This study aims to determine if treatment with apixaban, compared with aspirin, will reduce the risk of ischemic stroke and systemic embolism in patients with device-detected sub-clinical atrial fibrillation and additional risk…
- Trial name
- ARTESiA (NCT01938248)
- Testing
- Apixaban, aspirin
- Where
- 130 sites in United States, Belgium and 11 more
- Volunteers
- 4,012 people
- Sponsor
- Population Health Research Institute
Dental Implant Failed, Peri-Implantitis
20-year Implant Survival in Periodontally Healthy and Compromised Patients
The aim of this study will be to compare the long-term outcomes of sandblasted and acid-etched (SLA) implants in patients previously treated for periodontitis and in periodontally healthy patients (PHP) after a follow-up of at…
- Conditions
- Dental Implant Failed, Peri-Implantitis, Bone Loss
- Trial name
- NCT04983758
- Testing
- Oral Rehabilitation with dental implants
- Where
- Italy
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Degenerative Disc Disease, Spondylolisthesis
MLX/XLX ACR Expandable Lumbar Interbody Implants
The objective of this study is to evaluate the safety and performance of thoracic and/or lumbar spine surgery using the MLX and XLX ACR interbody implants as measured by reported complications, radiographic outcomes, and clinical…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Degenerative Scoliosis
- Trial name
- NCT04420143
- Where
- 4 sites in United States
- Volunteers
- 109 people
- Sponsor
- NuVasive
Drug-Refractory Epilepsy
Rechargeable Implantable Vagus Nerve Stimulation System for Drug-Refractory Epilepsy
To evaluate the performance of automatic stimulation mode of a new rechargeable implantable vagus nerve stimulation system for drug-refractory epilepsy
- Trial name
- NCT05993117
- Testing
- G114R VNS system
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Degenerative Disc Disease
Retrospective Review of Integrity Implants FlareHawk® for Lumbar Fusion
This is a retrospective clinical study (chart review) of patients who have previously undergone Transforaminal Lumbar Interbody Fusion or Posterior Lumbar Interbody Fusion surgery with the FlareHawk expandable interbody fusion…
- Trial name
- NCT04057235
- Testing
- FlareHawk Interbody Fusion System
- Where
- 3 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Integrity Implants Inc.
Immediate Implant Placement
Evaluation of the Magnesium Shield Compared to Dual Zone Grafting Approach in Immediate Implant Site Management
Will (GBR) by application of magnesium membrane with immediate implant will have more volume gain , higher pink esthetic score, and lower visual analogue scale than dual zone grafting technique? Several methods have been…
- Trial name
- NCT07492576
- Testing
- GBR surgery using magnesium Shield, Dual Zone concept (DZ) technique
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Arthroplasty, Replacement, Shoulder, Arthritis Shoulder
Three Year Outcomes After Shoulder Arthroplasty
The purpose of this multicenter observational cohort study is to evaluate three-year outcomes in adults who underwent anatomic or reverse total shoulder arthroplasty using a contemporary shoulder implant system.
- Conditions
- Arthroplasty, Replacement, Shoulder, Arthritis Shoulder, Rotator Cuff Arthropathy
- Trial name
- NCT07815535
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Vani Sabesan
Ventricular Tachycardias
Does Timing of VT Ablation Affect Prognosis in Patients With an Implantable Cardioverter-defibrillator?
The purpose of this study is to assess whether the burden of untreated non-sustained ventricular tachycardias (VTs), or episodes treated with anti-tachycardia pacing, correlates with appropriate implantable cardiac defibrillator…
- Trial name
- PARTITA (NCT01547208)
- Testing
- Immediate radiofrequency ablation of ventricular tachycardia, Radiofrequency ablation of ventricular tachycardia
- Where
- 21 sites in Belgium, Czechia and 5 more
- Volunteers
- 590 people
- Sponsor
- IRCCS San Raffaele
Dental Implant Healing, Partial Edentulism Class 1
Internal Irrigation Surgery
Heat generated during osteotomy and implant placement may cause thermal injury to bone and adversely affect healing and osseointegration.
- Conditions
- Dental Implant Healing, Partial Edentulism Class 1, Partial Edentulism Class II, Partial Edentulism Class 3
- Trial name
- NCT07715825
- Testing
- Irrigation-Integrated Surgical Guide, Conventional Surgical Guide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Atrial Fibrillation, Stroke
Predictors of Atrial Fibrillation in Patients Undergoing Implantable Loop Recorder Implant
Implantable Loop Recorders (ILR) are small devices the size of a memory stick, which are implanted to investigate stroke, palpitations and fainting episodes.
- Trial name
- NCT04724889
- Testing
- blood test
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Hybrid Crowns on Single Implants in Esthetic Zone
Patient Satisfaction and Crestal Bone Loss of Polymer Infiltrated Ceramic Network Versus Lithium Disilicate Implant Hybrid Abutment Crowns in Esthetic Zone
P: Population: Patients requiring single unit implant restoration in esthetic zone I: Intervention: Polymer-infiltrated-ceramic-network abutment crown (VITA Enamic-VITA Zahnfabrik) C: Comparison: Lithium disilicate ceramic…
- Trial name
- NCT03333889
- Testing
- Vita Enamic hybrid crown, emax hybrid crown
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nasal Valve Incompetence
Alar Batten Graft vs Latera for Nasal Valve Collapse
Nasal obstruction is a common complaint for the patient presenting to the Otolaryngologist and/or the Facial Plastic surgeon. There are numerous potential causes of nasal obstruction, with more easily addressed pathologies such…
- Trial name
- NCT03793218
- Testing
- Latera Device, Alar Batten Graft
- Sponsor
- University of Virginia
Hammertoe, Hammer Toe Syndrome
Mg Alloy DrillPins in Hammertoe Deformity Correction
This is a prospective, single-arm clinical feasibility study evaluating the safe application of a novel lean absorbable magnesium-zinc-calcium alloy (ZX00) drill pin (RemeOs™ DrillPin) for the surgical correction of hammertoe…
- Trial name
- NCT07121790
- Testing
- Implant Mg-based RemeOs™ drillpins
- Volunteers
- 20 people
- Sponsor
- Bioretec Ltd.
Dental Implants, Dental Materials
Hybrid Polyetheretherketone (PEEK)-Acrylic Resin Prostheses and the All-on-4 Concept for Full Arch Rehabilitation
It is necessary to evaluate the outcome of implant supported fixed prosthetic rehabilitations using peek material. To test this, the study design to be used will be a prospective single cohort to evaluate the long term outcome of…
- Conditions
- Dental Implants, Dental Materials, Mandible, Prosthesis Survival
- Trial name
- AO4PEEKDev (NCT04446078)
- Testing
- PEEK- acrylic resin prosthesis supported by 4 dental implants
- Where
- Portugal
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Malo Clinic
Pacemaker, Implantable Cardioverter Defibrillator
Comparison of Upper Extremity Function, Physical Activity Levels and Peripheral Muscle Strength, Fear of Movement, Balance, Activities of Daily Living and Quality of Life in Patients With Pacemakers According to Pacemaker Type
While research and clinical practice have demonstrated the objective benefits of pacemaker use on mortality, morbidity, and quality of life, some patients do not experience the expected level of improvement following device…
- Conditions
- Pacemaker, Implantable Cardioverter Defibrillator, Cardiac Resynchronization Therapy
- Trial name
- NCT06775691
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erol Olcok Corum Training and Research Hospital
Tachycardia, Ventricular, Ventricular Fibrillation
ADVANCE CRT - D: Antitachycardia Pacing (ATP) Delivery for Painless Implantable Cardioverter Defibrillator (ICD) Therapy
To compare the efficacy of RV and BiV ATP for the termination of ventricular arrhythmias in patients who are candidates to a cardiac resynchronisation therapy (CRT) and have a Class I or IIA indication for ICD implantation.
- Trial name
- ADVANCE-CRTD (NCT00147290)
- Testing
- Implantable Cardiac Defibrillator
- Where
- Italy
- Volunteers
- 526 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
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