Clinical trials: Implants
Heart Failure, Atrial Fibrillation (AF)
Bachmann Bundle Pacing for Prevention of New-Onset Atrial Fibrillation in Patients With Heart Failure
This is a multi-center, prospective, single-blind, randomized controlled clinical trial to evaluate the efficacy and safety of Bachmann bundle pacing (BBP) in preventing new-onset atrial fibrillation (AF) in patients with chronic…
- Conditions
- Heart Failure, Atrial Fibrillation (AF), Cardiac Insufficiency
- Trial name
- NCT07547449
- Testing
- Bachmann Bundle Pacing, Right Atrial Appendage Pacing
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Fu Wai Hospital, Beijing, China
Edentulous; Alveolar Process, Atrophy
Transcrestal Lateral Sinus Floor Elevation in Implant Therapy
This is a non-inferiority study to evaluate whether L-PRF achieves similar or perhaps better results in bone gain, compared with "the golden standard" DBBM, after trans-crestal sinus floor elevation.
- Trial name
- NCT03496038
- Testing
- L-PRF, DBBM
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Total Knee Arthroplasty, Knee Replacement
Investigating Patient Satisfaction With Smart Knee Implants
The main goal of this study is to see if there is a connection between the social and economic resources available in a patient's neighborhood (measured by the Area Deprivation Index, ADI) and their recovery after knee…
- Conditions
- Total Knee Arthroplasty, Knee Replacement, Knee Replacement Arthroplasty, Knee Osteoarthritis
- Trial name
- NCT06968143
- Testing
- Smart Knee Implant
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Diabetic Macular Edema, Macular Edema Due to Diabetes Mellitus
OCT and OCT-Angiography Biomarkers of Treatment Response to Dexamethasone Implant in Macular Edema Due to Retinal Vascular Diseases - DME and RVO
The purpose of this pilot study is to evaluate different imaging parameters in patients with previously treatment-naive DME and ME due to RVO before and after treatment with dexamethasone implant, in order to find specific…
- Conditions
- Diabetic Macular Edema, Macular Edema Due to Diabetes Mellitus, Retinal Vein Occlusion
- Trial name
- NCT06332690
- Testing
- dexamethasone implant
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Multimedica
Peri-Implantitis, Implant Complication
Diode Laser for Treatment of Peri-implantitis
The primary objective is to evaluate the clinical and patient-centered outcomes of non-surgical mechanical debridement with adjunctive repeated diode laser application (test) in comparison with conventional surgical treatment and…
- Trial name
- LAS (NCT03383120)
- Testing
- Laser treatment, Surgical treatment with adjunctive systemic antibiotics
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Geneva, Switzerland
Ovarian Cancer, Peritoneal Carcinomatosis
Imaging of Peritoneal Carcinomatosis From Ovarian Carcinoma Patients
The purpose of this study is to determine if NIF fluorescent imaging is an effective approach to detect the gross ovarian tumoral tissues and peritoneal implants in Ovarian cancer patients.
- Trial name
- OV-AP-ICG-IV (NCT01834469)
- Testing
- iv injection of ICG
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Edentulous Jaw
Time-dependent Change in the Retention Force of the Implant Overdenture
This descriptive longitudinal study aimed to investigate the retention force of implant-supported overdentures applied to edentulous individuals at Marmara University Faculty of Dentistry, examine the retention force and its…
- Trial name
- NCT05675566
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Knee Osteoarthritis
Kinematics of Contemporary Knee Arthroplasty
Total joint replacement is an efficacious treatment for osteoarthritis of hips and knees. Both total knee replacement (TKR) and total hip replacements (THR) have excellent implant survivorship.
- Trial name
- NCT02965690
- Testing
- Zimmer Biomet NexGen CR, Medacta International GMK Sphere
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Oslo University Hospital
Diabetic Retinopathy
A Study of PER-001 in Participants With Diabetic Retinopathy
This is a Phase 2a, randomized, single-masked (participant), sham controlled clinical study.
- Trial name
- NCT06003751
- Testing
- PER-001 Intravitreal Implant - Low Dose, PER-001 Intravitreal Implant - High Dose
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Perfuse Therapeutics, Inc.
Cochlear Implant Users
Assessment of a Method to Improve Cochlear Implant Users' Speech Perception in Noisy Environments While Maintaining Their Ability to Determine Where a Sound Originates From
The goal of this clinical trial is to determine if a new algorithm can improve speech perception for cochlear implant users. The main questions it aims to answer [is/are]: Does the algorithm improve speech perception in noisy…
- Trial name
- NCT07323862
- Testing
- Modifying audio input for cochlear implant processor
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Illinois at Urbana-Champaign
Advanced Heart Failure
First in Human Study of the Icoms Flowmaker
The Icoms® FlowMaker® is a cardiac assist system in the true sense of the word. As assisting means to help or rescue, its function is providing assistance to the heart, which will continue to have its own hemodynamic pump…
- Trial name
- FAIR (NCT07632586)
- Testing
- Cardiac assist device implantation during surgical intervention
- Where
- 2 sites in Czechia, France
- Volunteers
- 10 people
- Sponsor
- FineHeart
Dental Implants, Dental Implants, Single-tooth
Comparison Between Two Different Healing Abutments in Single Posterior Implants
The aim of this randomized clinical trial is to evaluate the volumetric analysis of peri-implant soft tissues after 3 months of the use of a prefabricated healing abutment with scan peg in comparison to customized healing…
- Trial name
- NCT06682559
- Testing
- Prefabricated healing abutment with scan peg, Customized healing abutment
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Myocardial Ischemia(Implanted Drug-eluting Stents Because of Ischemic Heart Disease(Stable Angina, Acute Coronary Syndrome))
Impact of IntraVascular UltraSound Guidance on the Outcomes of Xience Prime Stents in Long Lesions (IVUS-XPL Study): Retrospective and Prospective Follow-up Study
The investigator aimed to evaluate the long-term (up to 10 years) follow-up of the patients who enrolled the IVUS-XPL study (Impact of IntraVascular UltraSound Guidance on the Outcomes of Xience Prime Stents in Long Lesions)…
- Trial name
- NCT03866486
- Where
- South Korea
- Volunteers
- 1,400 people
- Sponsor
- Yonsei University
Cochlear Implant Users
Cochlear Implants and Listening Effort: the Interaction of Cognitive and Sensory Constraints
This study examines how cochlear implant users understand and comprehend speech in realistic communication situations. Through six experiments measuring listening effort via pupillometry and discourse comprehension, we will…
- Trial name
- NCT07279441
- Testing
- Experiment 1: Syntactic and Semantic Context, Experiment 2: False Hearing and Context Overuse, Experiment 3: Two-Sentence Problem
- Where
- 2 sites in United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Bone Resorption
Association of Force Distribution and Bone Resorption
To investigate the residual ridge resorption at anterior and posterior maxillary and posterior mandibular ridges among conventional complete dentures and implant overdenture wearers, and determine its association with the…
- Trial name
- NCT03026894
- Testing
- Panoramic Radiograph, T-Scan III occlusal system
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Opioid Use, Unspecified, Remifentanil
Anesthesia for Vascular Access Devices
Our aim was to investigate whether remifentanil use in both infusion and bolus techniques could provide sufficient sedation and analgesia without serious adverse effects for central venous access device procedures under monitored…
- Conditions
- Opioid Use, Unspecified, Remifentanil, Sedation Complication, Analgesia
- Trial name
- NCT04749069
- Testing
- Comparison of pain intensity rating scale
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Ventricular Fibrillation
Canadian Registry of ICD Implant Testing Procedures
To document practices in Canadian ICD implant centres around defibrillation therapy efficacy testing.
- Trial name
- NCT00848341
- Testing
- GUIDANT ICD SYSTEM
- Volunteers
- 261 people
- Sponsor
- Guidant Corporation
Dental Implants
New IMPLANTARY SURGERY Protocol ASSISTED BY PASSIVE ROBOTIQUE: Pilot Study
The use of a passive robotic system allows the practitioner to widen the field of indications of flapless surgical access to the implant with an increased operative security and the possibility of an operative modification of the…
- Trial name
- NAVIMPLANT (NCT05218941)
- Testing
- Implant surgery assisted by passive robotics, Conventional implant surgery
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Toulouse
Psychological Distress
CARE-BI:a Pilot Study to Improve Patient Comfort and Reduce Psychological Distress During IA Removal
The goal of this research study is to learn about the rate of posttraumatic stress disorder (PTSD) experienced by women after undergoing gynecologic brachytherapy.
- Trial name
- NCT07335302
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- M.D. Anderson Cancer Center
Ventricular Fibrillation, Ventricular Tachycardia
Influence of Home Monitoring on the Clinical Status of Heart Failure Patients With an Impaired Left Ventricular Function
Re-hospitalizations or deaths by worsening heart failure are often preceded by distinct trends of clinical parameters such as atrial or ventricular arrhythmia, activity, heart rate variability, or ventricular ectopy.
- Conditions
- Ventricular Fibrillation, Ventricular Tachycardia, Congestive Heart Failure
- Trial name
- IN-TIME (NCT00538356)
- Testing
- ICD or CRT-D with Home Monitoring feature deactivated, ICD or CRT-D with Home Monitoring feature activated
- Where
- 39 sites in Australia, Austria and 5 more
- Volunteers
- 720 people
- Sponsor
- Biotronik SE & Co. KG
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