Clinical trials: Implementation, open to volunteers
Lung Cancer
Lung Cancer Screening Implementation Project in the Brazilian Public Health Care System (LUSIP)
A prospective, longitudinal, single-arm interventional study of lung cancer screening.
- Trial name
- LUSIP (NCT07279948)
- Where
- Brazil
- Volunteers
- 477 people
- Sponsor
- AstraZeneca
Neutropenic Fever
Antibiotic Stewardship in Suspected Neutropenic Fever (ASTERIC Trial)
Executive Summary Background: Neutropenic Fever (NF), or febrile neutropenia, occurs in patients with early stage and metastatic solid tumours, non-leukaemic haematological cancers and acute leukaemia.
- Trial name
- NCT06794320
- Testing
- NF Protocol, ASTERIC protocol
- Where
- Hong Kong
- Volunteers
- 648 people
- Sponsor
- The University of Hong Kong
Hepato Cellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma
Outpatient Versus Inpatient Care Pathway for Intra-arterial Treatment of Primary Liver Cancer (CHOC)
Randomized multicentre trial comparing two care organisations (ambulatory vs conventional inpatient) for patients undergoing transarterial chemoembolization (TACE) or radioembolization (TARE) for primary liver cancer (Hepato…
- Trial name
- CHOC (NCT06990659)
- Testing
- Ambulatory care, Conventional inpatient care
- Where
- 19 sites in France
- Volunteers
- 206 people
- Sponsor
- University Hospital, Angers
Type Two Diabetes Mellitus
Scaling up the DSMES Learning Collaborative
A multicomponent implementation strategy bundle designed to improve Diabetes Self-Management Education and Support (DSMES) referral and utilization in rural primary care clinics.
- Trial name
- NCT07888179
- Testing
- Multicomponent Implementation Strategy (MCIS) Bundle, Standard of Care
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mary Lacy
Blood Pressure Monitoring, Home, Hypertension
Implementation Strategies for Self-Measured Blood Pressure Monitoring in Racially and Ethnically Diverse Populations
This clinical trial aims to assess the impact of patient-focused and clinical-focused implementation strategies on blood pressure control.
- Trial name
- INSPIRED (NCT06871462)
- Testing
- BP monitor use training and app training, Online patient portal enrollment and training, SMS reminders to take blood pressure
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of California, San Francisco
Frail
AI-Assisted Rehabilitation In Frailty
This study investigates the effectiveness and implementation of an AI-assisted rehabilitation tool for adults with frailty in the real-world.
- Trial name
- NCT07176520
- Testing
- AI-assisted rehabilitation, usual care only
- Volunteers
- 220 people
- Sponsor
- SingHealth Community Hospitals
Aging, Preventive Care
Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 2
This study consists of three aims focused on examining the feasibility of adding the Geriatric Resources and Assessment for the Care of Elders (GRACE) model to structured Annual Wellness Visits (AWVs) to improve patient and…
- Conditions
- Aging, Preventive Care, Multimorbidity, Palliative Care
- Trial name
- SPIRE2 (NCT07166861)
- Testing
- Annual Wellness Visit, Annual Wellness Visits + Geriatric Resources and Assessment for the Care of Elders (AWV + GRACE)
- Where
- 4 sites in United States
- Volunteers
- 7,140 people
- Sponsor
- Massachusetts General Hospital
Guideline Implementation, Physiotherapy
Physiotherapy Practice in Flemish Nursing Homes
The goal of this observational study is to evaluate the extent to which physiotherapy sessions in Flemish nursing homes adhere to the IAGG-GARN guidelines and to explore factors influencing clinical practice among…
- Conditions
- Guideline Implementation, Physiotherapy, Nursing Homes, Focus Group
- Trial name
- NCT07576751
- Testing
- Mapping therapy sessions
- Where
- 4 sites in Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasselt University
HIV Infections, HIV Prevention
Community-based Outreach and Navigation for Nurse-led Engagement in HIV Care and Treatment
Many people who are experiencing homelessness are at high risk for HIV, but they often have trouble getting HIV prevention or treatment.
- Conditions
- HIV Infections, HIV Prevention, Homeless Persons, Homelessness
- Trial name
- CONNECT (NCT07870603)
- Testing
- CONNECT (status-neutral, nurse-led on-site HIV service delivery), Standard of Care (referral-based outreach)
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Donaldson Conserve
Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR
New Taipei City 888 Digital Medical AI Platform for Prevention and Care of the Three Highs and Cardio-Renal-Vascular Diseases
Non-communicable diseases (NCDs), or chronic diseases, are a major public health burden globally and in Taiwan, and control of the "three highs" (hypertension, dyslipidemia, and hyperglycemia) is a national priority.
- Conditions
- Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR, Cardiovascular Disease Risk Factor, Cardiovascular Disease Prevention
- Trial name
- DIGICARE-DREAM (NCT07588256)
- Testing
- Interactive digital modules, Antihypertensive Medication Management
- Where
- Taiwan
- Volunteers
- 4,162 people
- Sponsor
- New Taipei City Medical Association
Cervical Cancer Screening, HIV
Impact of a Single Versus Multiple Visits on the Cervical Cancer Screening Completeness, Feasibility and Acceptability Among Women Living With HIV in Cameroon
Context. Cervical cancer (CC) is a leading cause of death among women living with HIV (WLHIV) in resource-limited settings. Yet, effective methods for screening and preventing CC are available.
- Trial name
- OptiTri_GC (NCT07177170)
- Testing
- Differentiated screening delivery, Single visit
- Where
- Cameroon
- Volunteers
- 1,422 people
- Sponsor
- Institut de Recherche pour le Developpement
Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Artery Calcification
Health Enhanced Artery Risk Tracking With Widespread Implementation and Screening Effort in ASCVD (HEARTWISE-ASCVD)
This multi-site study will test whether an opportunistic AI-based CAC screening and notification intervention can improve cholesterol treatment and lower cholesterol levels in adults.
- Trial name
- HEARTWISE (NCT07355894)
- Testing
- AI-Detected CAC Notification and Care Facilitation
- Where
- 6 sites in United States
- Volunteers
- 120,000 people
- Sponsor
- Stanford University
Cervical Cancer Screening, Gynecologic Cancers
Compliance to Cervical Cancer Chemoradiation Guidelines: A Multicentric Implementation Audit and Resource Assessment Initiative of National Cancer Grid of India
This is a combination of retrospective and prospective observational study that will be performed across NCG and other participating centers to report compliance to chemoradiation for cervical cancer.
- Conditions
- Cervical Cancer Screening, Gynecologic Cancers, Treatment Compliance, Chemoradiotherapy
- Trial name
- NCG-Compliance (NCT07290972)
- Testing
- Not applicable- observational study
- Where
- 2 sites in India
- Volunteers
- 618 people
- Sponsor
- Tata Memorial Hospital
Self Efficacy, Infant Development
Connecting Families to Improve Parental Self-efficacy and Parent Psychosocial and Infant Health Outcomes in the NICU
Preterm infants, 1 in 12 Canadian births, are at a significant increased risk of poor health outcomes, resulting in high healthcare burden.
- Conditions
- Self Efficacy, Infant Development, eHealth, Mental Health Wellness 1
- Trial name
- NCT05853666
- Testing
- CNH+
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Families With Infants
HealthySteps + PlayReadVIP
This study aims to investigate the effectiveness and implementation outcomes for the integration of two evidence-based practices and interventions (EBPIs) within pediatric primary care settings: HealthySteps (HS), which provides…
- Trial name
- NCT06941337
- Testing
- HealthySteps (HS), PlayReadVIP
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Heart Failure
Feasibility Study on the Implementation of a Program to Facilitate the Return Home of Patients With Heart Failure Following Hospitalization, Led by a Coordinated Multidisciplinary Team Based on the "Team-based Care" Model
Heart failure is a common heart condition that often leads to hospital stays and repeat readmissions. When patients leave the hospital, coordinating patient care between the hospital and the local healthcare team (family doctor…
- Trial name
- TEAM-IC (NCT07849361)
- Testing
- Intervention Arm - TEAM-IC
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Sant'Innovation
Advanced Heart Failure, Heart Transplantation
TORCH-LATAM-002: Regional Pathway for Adult Heart Transplant Evaluation and Candidacy
TORCH-LATAM-002 is a pragmatic stepped-wedge cluster randomized trial evaluating an integrated regional pathway for adults with advanced heart failure who require specialized heart transplant evaluation and a documented candidacy…
- Conditions
- Advanced Heart Failure, Heart Transplantation, Acquired Heart Disease
- Trial name
- TORCH-002 (NCT07836803)
- Testing
- TORCH Adult Heart Transplant Evaluation and Candidacy Pathway
- Volunteers
- 360 people
- Sponsor
- CardioVision International Tech, S.A.S. de C.V.
Liver Cirrhosis
Evaluation of Remote Monitoring of Liver Cirrhosis Patients
The goal of this longitudinal prospective study is to investigate disease course in patients with liver cirrhosis treated in hospitals that implemented a remote monitoring care pathway as part of their standard liver cirrhosis…
- Trial name
- NCT06746246
- Volunteers
- 750 people
- Sponsor
- Maastricht University Medical Center
Opioid Use Disorder, Opioid Use Disorders
Systems Analysis and Improvement to Optimize Opioid Use Disorder Care Quality and Continuity for Patients Exiting Jail
This study evaluates the effectiveness of a health systems strategy (the Systems Analysis and Improvement Approach - SAIA) that packages systems engineering tools (including cascade analysis, flow mapping, and continuous quality…
- Trial name
- SAIA-MOUD (NCT06593353)
- Testing
- Systems Analysis and Improvement Approach (SAIA)
- Where
- United States
- Volunteers
- 4,186 people, healthy volunteers welcome
- Sponsor
- University of Washington
Opioid Abuse (Disorder)
Improving Jail Response to the Overdose Crisis: A Hybrid Trial of Jail ECHO to Improve MOUD Implementation and Public Health Outcomes
This project tests a training strategy to help rural jails start or increase their use of medications to treat opioid use disorder (MOUD - methadone, buprenorphine, naltrexone).
- Trial name
- J-ECHO OPS (NCT07637994)
- Testing
- Project ECHO
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
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