Clinical trials: In Vitro Fertilization
IVF, Luteal Phase Defect
Luteal Phase Support In IVF Women Using GnRH Agonist
Lately, the role of GnRH agonist as luteal phase support has been recommended by various studies though the mechanism is still debatable.
- Trial name
- NCT04174378
- Testing
- Decapeptyl 0.2mg
- Where
- Malaysia
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Infertility, Female
The Effect of Progressive Muscle Relaxation and Laughter Therapy on Women Undergoing In Vitro Fertilization
Purpose: This study was aimed to evaluate the effect of progressive muscle relaxation exercises and laughter therapy on the mental health and treatment outcomes of women receiving IVF treatment.
- Trial name
- NCT04782882
- Testing
- Progressive muscle relaxation+laughter therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Reproductive Techniques, Assisted, DNA Methylation
First Live Birth Rate With eSET After Preimplantation Methylome Screening (PIMS) Versus Conventional In-vitro Fertilization
To determine whether using DNA methylome to select embryos can increase the live birth rate.
- Trial name
- NCT05442125
- Testing
- Using DNA methylome to select embryos, Using morphologic score to select embryos
- Where
- 28 sites in China, Thailand
- Volunteers
- 1,146 people, healthy volunteers welcome
- Sponsor
- Shandong University
Embryo/Fetus Death, Blastocyst Disintegration
Assessment of Implantation Potential of Embryos by Time-lapse Technology
1. Culture conditions of developing embryos are highly controlled in the Embryoscope and are monitored by Time-lapse videography to produce 3D images at different stages.This cannot be done under conventional culture conditions.
- Conditions
- Embryo/Fetus Death, Blastocyst Disintegration, Aneuploidy, Complication of Implant
- Trial name
- Embryoscope (NCT01760278)
- Testing
- recombinant Follicle Stimulating Hormone (rFSH)
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bloom IVF and Fertility Centre
Endometrial Receptivity and Success Rate of IVF
Pilot Study on Molecular Quantitation and Sequencing of Endometrial Cytokines Gene Expression and Their Effect on the Outcome of In-vitro Fertilization (IVF) Cycle
Pilot study on molecular quantitation and sequencing of endometrial cytokines gene expression and their effect on the outcome of in-vitro fertilization (IVF) Cycle
- Trial name
- NCT01809509
- Testing
- Endometrial biopsy
- Where
- 2 sites in Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
in Vitro Fertilization
Improvement of in Vitro Fertilization Implantation by Soluble CD146 Dose in Embryonic Culture Environment
The study of implantation potential of the embryo stay a priority in In Vitro Fertilization (IVF). Indeed, the selection of embryos to transfer is actually based in routine check on morphologic criteria, approved by literature…
- Trial name
- AMIFIV (NCT03785119)
- Where
- France
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
IVF
Comparative Study Between Fresh and Frozen Embryo Transfer in PCOS Patients Undergoing IVF Treatment
The objective of our study is to compare in vitro fertilization (IVF) outcomes between fresh embryo transfer (ET) and frozen-thawed ET in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT05167838
- Testing
- fresh embryo transfer, Frozen embryo transfer
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infertility
Comparison of Alternative Embryo Culture Systems
This study will compare two alternative embryo culture systems. Embryos from each patient will be randomly assigned to one of two systems. One group will be cultured conventionally in oil-covered droplets in dishes.
- Trial name
- NCT02028897
- Testing
- Conventional embryo culture, Enclosed embryo culture
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bruce Shapiro M.D.
Female Infertility Due to Nonimplantation of Ovum, Complications Associated With Artificial Fertilization
Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression
The purpose of this study is to assess the non-inferiority of a multidose GnRH antagonist (cetrorelix) regimen to a GnRH agonist (triptorelin) long protocol in young infertile women undergoing ovarian stimulation with Pergoveris…
- Trial name
- Pergoveris (NCT01565265)
- Testing
- Pergoveris in long protocol with GnRH agonist, Pergoveris in GnRH antagonist protocol
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Infertility
Antagonist Protocol in IVF
The antagonist protocol in a novel method of stimulation in the in vitro fertilization (IVF) patients. It has been tried in poor responders, polycystic ovary (PCO) patients and normal females undergoing IVF.
- Trial name
- NCT02335736
- Testing
- Gonadotropins releasing hormone antagonist
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Anxiety, Pregnancy Outcomes
Effect of Breathing Exercises on Embryo Transfer Outcomes
Breathing exercises are being used in many different clinical issues in the area of medicine. Also in gynecological practice, especially during labor, breathing exercises are encouraged by health professionals to aid the…
- Trial name
- BreathIVF (NCT07109544)
- Testing
- Breathing Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eurofertil IVF Health Center
Luteal Phase Progesterone Levels
The Effect of Luteal Blood Progesterone Levels on Ongoing Pregnancy Rates
Progesterone (P4) is essential for the secretory development of endometrium and the maintenance of early pregnancy. In the luteal phase following controlled ovarian stimulation in in vitro fertilization (IVF) treatment, P4…
- Trial name
- NCT04128436
- Testing
- Taking blood samples for analyzing progesterone levels
- Where
- 3 sites in Brazil, Denmark and 1 more
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Infertility
Navigating Health Insurance Selection for IVF Benefits
The purpose of this study is to evaluate the effectiveness of an educational intervention on health insurance literacy and utilization of in vitro fertilization (IVF) insurance benefits.
- Trial name
- NCT05663645
- Testing
- Health insurance educational guide
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Intrauterine Abnormalities in Infertility
SIGnificance of Routine Hysteroscopy Prior to a First 'in Vitro Fertilization'(IVF) Treatment Cycle
BACKGROUND: Despite the numerous advances in the field of in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI), there still exists a maximum implantation rate per embryo transferred of about 30%.
- Trial name
- inSIGHT (NCT01242852)
- Testing
- Office hysteroscopy (in combination with a 'Saline Infusion Sonography'(SIS))
- Where
- Netherlands
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Sterility, Placenta; Implantation
A Lifestyle Intervention to Improve in Vitro Fertilization Results
Embryo adhesion and placentation depend on tissue plasminogen activator (tPA)-mediated activation of brain-derived neurotrophic factor, vascular endothelial growth factor and other growth factors, formation of hemidesmosomes, and…
- Conditions
- Sterility, Placenta; Implantation, Risk Reduction Behavior, Lifestyle
- Trial name
- W+D (NCT02648555)
- Testing
- Daily walking, Dietary recommendations
- Where
- Brazil
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
Maternal Cardiometabolic Health, Infertility
St Mary's Assisted Reproductive Technology and Cardiometabolic Health: Modifiable Targets for Multimorbidity Prevention (START-HEALThY)
The main causes of death in women are conditions affecting the heart and blood vessels (cardiovascular disease, CVD). Women who have difficulties getting pregnant (infertility) may be at increased risk, but the reasons for this…
- Conditions
- Maternal Cardiometabolic Health, Infertility, Assisted Reproductive Technology, Cardiovascular Health
- Trial name
- START-HEALThY (NCT07173569)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Female Infertility
There is a Value of Luteinizing Hormone Predictive of in Vitro Fertilization Treatment Outcome in Antagonist Protocols?
This study, prospective randomized controlled trial, tried to identify a cut off value of luteinizing hormone predictive of in vitro fertilization outcome in a fixed or flexible gonadotropin-releasing hormone antagonist…
- Trial name
- NCT02328924
- Testing
- LH value
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- U.O.S. Procreazione Medicalmente Assistita e Congelamento Gameti
Acupuncture, in Vitro Fertilization
The Differences of Oocyte Maturation, Granulosa Cell Apoptosis Index Between Electroacupuncture And Sham Groups IVF
Interventional studies compared electroacupuncture group versus sham electroacupuncture group to granulosa cell apoptosis index, oocyte maturation, GDF9 and BMP15 levels, and fertilization rate in in vitro fertilization program
- Conditions
- Acupuncture, in Vitro Fertilization, BCL2 Gene mRNA Overexpression, Oocyte Maturation
- Trial name
- NCT03627533
- Testing
- Electroacupuncture
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Infertility
Mitochondrial Activity of Cumulus Cells From the Cumulus-oocyte Complex and Oocyte Competence
The need for non-invasive biomarkers of oocyte competency has become urgent as women increasingly delay attempts at childbearing.
- Trial name
- NCT02793752
- Testing
- Age
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Main Line Fertility Center
PCOS GnRH Antagonist and GnRH Agonist IVF/ICSI Cycles
In Vitro Fertilization Outcomes of Two Treatment Protocols in Women With Polycystic Ovary Syndrome
Outcomes of IVF/ICSI cycles of women with PCOS undergoing Gonadotropin Releasing Hormone (GnRH) agonist and GnRH Antagonist fixed protocol.
- Trial name
- PCOS and ivf (NCT01354275)
- Testing
- To compare the IVF/ICSI outcomes of GnRH Antagonist cycle versus GnRH agonist cycle, GnRH Antagonist
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bulent Haydardedeoglu