Clinical trials: Incision Infection
Surgical Site Infection, Brain Tumor
Infection Prevention Bundle in Brain Tumor Surgery
This study aimed to evaluate the effectiveness of an infection prevention bundle on surgical site infections in patients undergone brain tumor surgery.
- Trial name
- NCT04285697
- Testing
- infection prevention bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Surgical Site Infection
Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances
Comparative study of antimicrobial effectiveness evaluation of of 26ml Project X, 10.5ml Project X, 5.1ml Project X and Prevantics Maxi swabstick following ASTM E1173 - Standard test method for evaluation of preoperative…
- Trial name
- NCT04218110
- Testing
- Isopropyl alcohol & Chlorhexidine Gluconate Antiseptic, Prevantics 3.15 % / 70 % Swabstick
- Where
- Romania
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Professional Disposables International, Inc.
Surgical Site Infection (SSI), Wound Healing Complication
Subcutaneous Suture Versus no Subcutaneous Suture for Abdominal Wound Closure
Surgical site infections are among the most frequent complications after abdominal surgery and are associated with impaired wound healing, prolonged hospital stay, additional treatments, and increased healthcare costs.
- Trial name
- SUTURE (NCT07615517)
- Testing
- subcutaneous suture
- Where
- Germany
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- University Hospital Augsburg
Corneal Toxicity, Ototoxicity
A Comparison of Infection Rates Between Two Surgical Sites
Does the use of chlorhexidine scrub prior to cutaneous surgery on the face increase the chances of toxicity to the eyes or ears? In addition, does the us eof chlorhexidine scrub on the face prior to cutaneous surgery decrease the…
- Conditions
- Corneal Toxicity, Ototoxicity, Surgical Site Infection
- Trial name
- NCT01263262
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Surgical Site Infection, Mobile Applications
Wound And Symptom Tracking After Colorectal Surgery Using How2trak
The purpose of this study is to assess the feasibility of using a mobile application (app) called how2trak to improve people's experience, wound surveillance, and detection of surgical site infections (SSI) after colorectal…
- Conditions
- Surgical Site Infection, Mobile Applications, Surgery--Complications, Colorectal Surgery
- Trial name
- WATCH (NCT04869774)
- Testing
- How2Trak mobile application
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Surgical Site Infection, SCIP
Use of a Microbial Sealant to Reduce Surgical Site Infections.
Surgical site infections (SSI) are costly complications that may cause significant morbidity and increase the cost of care, particularly in colorectal surgery.
- Trial name
- Integuseal (NCT02241915)
- Testing
- Open Colorectal Surgery, Laparoscopic Surgery
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Surgical Wound Infection
Alexis O-Ring Wound Retractor for the Prevention of Post-cesarean Surgical Site Infections
Post cesarean section surgical site infection (SSI) is a common complication that can affect patient recovery and overall outcome.
- Trial name
- Alexis (NCT03365219)
- Testing
- Alexis O-Ring Wound Retractor, Standard Surgical Retractors
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Surgical Site Infection
Antibiotics for Prevention of SSI in Obese Women Undergoing CS
Effect of cephalexin plus metronidazole on SSI better than cephalexin alone in obese women undergoing CS
- Trial name
- NCT03736187
- Testing
- Cephalexin
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgical Site Infection
Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (ZX-ZP-0055)
This is a randomized, paired-comparisons design where each subject receives two of the planned treatments.
- Trial name
- NCT02296645
- Testing
- ZuraPrep, ChloraPrep
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Craniotomy Surgery, Preventive Health Care
The Effect of Bundle Application on Surgical Site Infection
Surgical site infections (SSI) are the most common complications after surgical operations and are in the top three in Healthcare Associated Infections (HIE).
- Trial name
- NCT06724354
- Testing
- The Surgical Site Infections Precaution Package Form includes the parameters that should be applied to patients before, during and after surgery.
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Skin Diseases, Surgical Site Infection
Effectiveness of Preoperative Surgical Scrubbing Using Clorhexidine Digluconate and Parachlorometaxylenol (ECP)
Despite the wide variety of products and antiseptic agents, no agent is ideal for every situation. The investigators would like to evaluate the difference in reducing bacterial load, using 4% chlorhexidine digluconate and 3%…
- Trial name
- ECP (NCT02500758)
- Testing
- Preparatory handwash, Preoperative surgical scrubbing using 3% PCMX, Preoperative surgical scrubbing using 4% CHG
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ricardo Becerro de Bengoa Vallejo
Surgical Site Infection
Perioperative Patient Skin Antiseptic Preparation Evaluation
This study will evaluate a new topical skin antiseptic perioperative preparation and the standard of care to determine efficacy on the rates of surgical site infections of surgical patients. Safety will also be assessed.
- Trial name
- NCT04756804
- Testing
- 70% v/v Isopropyl Alcohol Surgical Solution, 2%w/v Chlorhexidine Gluconate / 70% v/v Isopropyl Alcohol
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Surgical Site Infection
Safety Study to Evaluate the Contact Sensitizing Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA
This is a safety study to determine the skin sensitization potential of ZuraPrep™ and ZuraPrep™ without isopropyl alcohol (IPA) after repetitive patch applications to skin of human subjects.
- Trial name
- NCT02160587
- Testing
- Chloraprep, 0.9% Physiological Saline, ZuraPrep without IPA
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Cesarean Section
Sharp Versus Blunt Fascial Incision at Caesarean Section
The purpose of this study is to compare sharp and blunt fascial entry during caesarean section on the same patient. The study is performed on woman having cesarean section for the first time and who have not previously had lower…
- Trial name
- NCT01297725
- Testing
- Blunt right, sharp left, Blunt left, sharp right
- Where
- 2 sites in Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Rectal Cancer, Retention, Urinary
Incidence of Acute Urine Retention: Randomized Clinical Trial Comparing Early, Mid or Late Urinary Catheter Removal in Patients With Rectal Resection
DESIGN: Randomized, open-label and parallel clinical trial, assigned to early, mid, or late withdrawal of urinary catheter with a 1: 1: 1 allocation ratio.
- Conditions
- Rectal Cancer, Retention, Urinary, Urinary Tract Infections, Surgical Site Infection
- Trial name
- RAOREC (NCT04751149)
- Testing
- Removal of Urinary Catheter
- Where
- Spain
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Hospital Donostia
Cesarean Section Complications, Cesarean Wound; Dehiscence
PICO Negative Pressure Wound Therapy in Obese Women Undergoing Elective Cesarean Delivery.
A randomized controlled, parallel group, superiority, open-label, single-institution, Phase 3 interventional clinical trial to evaluate clinical outcomes in obese gravidas undergoing elective cesarean delivery whose wounds were…
- Conditions
- Cesarean Section Complications, Cesarean Wound; Dehiscence, Cesarean Wound Disruption
- Trial name
- NCT03414762
- Testing
- PICO Negative Pressure Wound Therapy, Standard Dressing
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Surgical Site Infection Following Cesarean Delivery
The Mepilex Cesarean Delivery Trial
The goal of this clinical trial is to learn whether using a silver-containing antimicrobial foam dressing (Mepilex Ag) can help prevent surgical site infections in patients undergoing cesarean delivery.
- Trial name
- MEPIDEL (NCT07066254)
- Testing
- Mepilex Ag Dressing, Standard Surgical Dressing (Telfa non-adhesive dressing, gauze, and Primapore adhesive bandage)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Surgical Site Infection, Capsular Contracture Associated With Breast Implant
Postoperative Antibiotics Following Primary and Secondary Breast Augmentation
Postoperative antibiotics are routinely used for implant-based breast augmentation at the investigators' institution. From 2017-2019, the investigators' institution has conducted approximately 270 primary and secondary breast…
- Conditions
- Surgical Site Infection, Capsular Contracture Associated With Breast Implant, Antibiotic Resistant Infection, Antibiotic Side Effect
- Trial name
- NCT04834310
- Testing
- Cefazolin, Cephalexin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Arthroplasty Complications, Amputation
Clinical Trial Comparing Negative Pressure Wound Therapy and Standard Dry Dressings
Negative pressure dressings are currently widely used in wound management. Their use is gradually being extended to surgical scars.
- Conditions
- Arthroplasty Complications, Amputation, Prosthesis-Related Infections
- Trial name
- BERLYTZ (NCT04520841)
- Testing
- Prevena TM, Dry dressing
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Surgical Site Infection Prevention, Nursing Education
Effectiveness of Digital Game-Based Learning in Teaching Surgical Site Infection Prevention to Nursing Students
This study aims to evaluate the effectiveness of digital game-based learning in teaching evidence-based surgical site infection prevention interventions to second-year nursing students.
- Trial name
- PreSSI-DGBL (NCT07423702)
- Testing
- Digital Game-Based Learning, Traditional Theoretical Education
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- hatice akaltun