Clinical trials: Indirect Calorimetry
Acute Respiratory Failure
New Indirect Calorimetry Device for Energy Expenditure Measurement
Energy expenditure (EE) in critically ill patients is highly variable depending on the initial severity of the disease and treatments. Clinicians need to measure EE by indirect calorimetry (IC) to optimize nutritional support.
- Trial name
- ICALIC (NCT02024958)
- Where
- Switzerland
- Volunteers
- 182 people
- Sponsor
- University Hospital, Geneva
Diet-induced Thermogenesis
Inter-Individual Variability in Early Diet-Induced Thermogenesis After a Standardized Meal
This study aims to characterize how individuals differ in their metabolic response to food intake, specifically focusing on early diet-induced thermogenesis (DIT).
- Trial name
- NCT07610759
- Testing
- Standardized Liquid Meal
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
no Condition, Community-dwelling 80+ Older Adults
Validation of Objectively and Subjectively Measured Physical Activity Against Energy Expenditure in Older Adults
Physical inactivity is identified as one of the most important modifiable risk factors for chronic diseases, functional loss and disability and reliable assessment tools of physical activity are crucial in both research and…
- Trial name
- NCT04821713
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Southern Denmark
Septic Shock
Urea-to-Creatinine Ratio as a Marker of Metabolic Transition in Septic Shock: A Comparison With Indirect Calorimetry
Urea-to-Creatinine Ratio as a Marker of Metabolic Transition in Septic Shock: A Comparison with Indirect Calorimetry. This study investigates whether the urea-to-creatinine ratio can serve as a simple marker of metabolic state in…
- Trial name
- NCT07412366
- Volunteers
- 40 people
- Sponsor
- Hospital Sao Domingos
Obesity and Overweight
How Metabolism Affects Weight Loss and Gain
This study examines why some individuals with obesity have difficulty losing weight, whereas some lean individuals struggle to gain weight.
- Trial name
- NCT06860776
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Type 1 Diabetes (T1D), Healthy Subjects
Effect of Artificial Sweetener (AFS) on Glucose Metabolism in Patients With Type 1 Diabetes (T1D)
The goal of this randomized crossover study is to test the prediction that consuming carbohydrates will affect insulin release differently depending on whether Non-Nutritive Sweeteners (NNSs) are consumed simultaneously.
- Trial name
- AFS_T1D (NCT06315725)
- Testing
- Sweet taste perception with/without sweet taste blockade
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Critically Ill
Indirect Calorimetry Versus Urea-creatinine Ratio to Evaluate Catabolism in Critically Ill Patients
This study aims to evaluate the efficiency of the urea/creatinine ratio as a catabolism marker compared to indirect calorimetry to optimize nutritional support in critically ill patients.
- Trial name
- NCT06244381
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Sao Domingos
Nutritional Therapy in an ICU, Critically Ill Patients Requiring Mechanical Ventilation
Will the Use of Respiratory Quotient ''RQ'' Improve Treatment Outcomes for Intensive Care Unit (ICU) Patients?
Introduction and assumptions of the research project: Patients treated in intensive care units (ICUs) require comprehensive treatment. Nutrition is an important and integral part of this therapy.
- Trial name
- RQCal (NCT07457554)
- Testing
- RQ guided nutrition, Standard Treatment (Guideline-Based)
- Where
- Poland
- Volunteers
- 236 people
- Sponsor
- Poznan University of Medical Sciences
Resting Energy Expenditure, Indirect Calorimetry
Comparison of the Effects of SIMV-PC and SIMV-VC Ventilation Modes on Resting Energy Expenditure
The primary objective of this prospective observational study is to compare the effects of synchronized intermittent mandatory ventilation in pressure-controlled mode (SIMV-PC) and volume-controlled mode (SIMV-VC) on resting…
- Trial name
- NCT07790341
- Testing
- Volume-controlled ventilation, Pressure-controlled ventilation
- Volunteers
- 41 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Maximal Rate of Fat Oxidation
Dietary Correlates of the Maximal Capacity for Fat Oxidation
There is a large variability in people's ability to burn fat during exercise. It is thought that differences in dietary intake can partly explain this variation, however this has not been comprehensively studied.
- Trial name
- NCT02070055
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Respiratory Failure
Evaluation of Oxygen Consumption and Energy Expenditure During Spontaneous Breathing Trial.
The purpose of this study is to compare the oxygen consumption and energy expenditure during the spontaneous breathing trial.
- Trial name
- NCT01757093
- Testing
- Automatic Tube Compensation plus CPAP, Continuous Positive Airway Pressure
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Metabolism, Nutrition
Assessment Metabolic Flexibility in Middle-aged Individuals: The Nutritional Impact of Cheese Consumption
The aim of the study will be to evaluate the impact of consumption of meat and dairy products from extensive or intensive farming on apparently healthy individuals aged between 45 and 65 years, a stage of life associated with…
- Trial name
- Kent'Erbas (NCT06012227)
- Testing
- kent'erbas cheese study
- Where
- Italy
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Anesthetized Healthy Patients (ASA 1 or 2) in the Supine Position, Excluding Head, Neck and Head Surgeries, Anesthetized Patient With Severe Systemic Disease (ASA 3 or 4)
Gas Kinetics and Metabolism in Anesthesia During Non Steady State
During clinical anesthesia, it is astonishing that CO2 monitoring consists mainly of end-tidal PCO2 to confirm endotracheal intubation and to estimate ventilation, and O2 monitoring consists of a single PO2 measurement to detect…
- Trial name
- NCT00225381
- Testing
- connection of measuring device to anesthesia circuit, drawing of blood sample through an arterial line, placed according to clinical criteria by primary anesthesia team, changing operating room bed position (head down and up position)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Critically Ill Patients, Acid-Base Disturbance
Bicarbonate Variation Monitoring With Indirect Calorimetry
Patients admitted to the intensive care unit frequently exhibit abnormal blood bicarbonate levels. These abnormalities are associated with patient outcomes and often prompt clinicians to modify management, either diagnostically…
- Conditions
- Critically Ill Patients, Acid-Base Disturbance, Indirect Calorimetry
- Trial name
- BICAR-CC (NCT07782658)
- Testing
- Indirect calorimetry measurement
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Hospices Civils de Lyon
Weight
Energy Expenditure Assessment of Premature Infants
The goal of this study is verify if the energy expenditure in preterm infant fed with human milk is different from preterm formula.
- Trial name
- NCT00769509
- Testing
- energy expenditure in preterm fed with preterm formula, assessment of energy expenditure
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Oswaldo Cruz Foundation
Continuous Renal Replacement Therapy, CO2 Removal
Plasma CO2 Removal Due to CRRT and Its Influence on Indirect Calorimetry
The aim of the present study is to assess the metabolic impact of Continuous Renal Replacement Therapy and overview the obstacles and important factors compromising the use of Indirect Calorimetry in CRRT and suggest a model to…
- Conditions
- Continuous Renal Replacement Therapy, CO2 Removal, Nutrition Poor, Acute Renal Failure
- Trial name
- MECCIAS (NCT03314363)
- Testing
- blood gas analysis under citrate predilution, filter replacement, IC
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Physical Fitness, Mitochondrial Function, Bioenergetics
Effects of Acute Exercise in Fasting and Fed States in Individuals With Different Aerobic Fitness Levels
The aim of this study is to investigate the effects of aerobic fitness level, feeding status, and acute exercise on whole-body metabolic fuel utilization and mitochondrial function in peripheral blood mononuclear cells (PBMCs) in…
- Conditions
- Physical Fitness, Mitochondrial Function, Bioenergetics, Mitochondria, Energy Metabolism
- Trial name
- NCT07813403
- Testing
- Acute Moderate-Intensity Cycling Exercise, Ad Libitum Mixed Meal
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Kidney Diseases, Metabolic Acidosis
Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5
The goal of this clinical trial is to learn about and test the effect of an acid/base diet, in chronic kidney patients with CKD stage 4 and 5 in an interventional study with a historical control.
- Conditions
- Kidney Diseases, Metabolic Acidosis, Renal Insufficiency, CKD
- Trial name
- REMA-CKD (NCT05970094)
- Testing
- Low PRAL
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Copenhagen
Critical Illness, Energy Requirement
Measured Versus Estimated Energy Requirement in the ICU Patients
The goal of this observational study is to compare energy requirements estimated by predictive equation and indirect calorimetry across different BMI categories, and to examine how these estimates, along with early nutritional…
- Conditions
- Critical Illness, Energy Requirement, Equation, Indirect Calorimetry
- Trial name
- NCT07024264
- Testing
- Total energy requirement calculated by predictive equation
- Where
- Taiwan
- Volunteers
- 133 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Nutrition Assessment, Critical Illness
Indirect Calorimetry: SensorMedics Vmax vs GE Carescape - a Method Comparison Study
Dosing of nutrition in PICUs is mainly based on patient weight and assumptions on clinical status. There is however poor correlation between these calculations and actual energy consumption measured with indirect calorimetry…
- Conditions
- Nutrition Assessment, Critical Illness, Children
- Trial name
- NCT02987309
- Where
- Norway
- Volunteers
- 6 people
- Sponsor
- Oslo University Hospital