Clinical trials: Individuals With Multiple Sclerosis, open to volunteers
Multiple Sclerosis
Physical Activity Intervention for Individuals Newly Diagnosed With MS
The proposed study is a parallel-group randomized controlled trial (RCT) designed to establish the behavioral mechanism underlying a 16-week physical activity (PA) behavioral intervention through its effects on the…
- Trial name
- ActivNMS (NCT07731659)
- Testing
- COM-B-based Physical Activity Behavior Change Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Multiple Sclerosis (MS) - Relapsing-remitting
Effects of Low-Load Blood Flow Restriction Exercise on Rectus Femoris Muscle Morphology in Individuals With Relapsing-Remitting Multiple Sclerosis
Multiple sclerosis (MS) is a chronic neurological disease associated with reduced muscle strength, impaired mobility, increased fatigue, and deterioration in muscle morphology.
- Trial name
- RRMS-BFR (NCT07645937)
- Testing
- Blood Flow Restriction Training, Low-Load Exercise Program
- Volunteers
- 30 people
- Sponsor
- Hanifi Bal
Multiple Sclerosis
Effects of Balance Exercises Performed With Different Visual Stimuli
The study aims to examine the effects of balance exercises applied with different visual stimuli on individuals with MS.
- Trial name
- NCT06387043
- Testing
- Balance exercises with Virtual Reality Glasses, Balance Exercises with Stroboscopic Glasses, Balance Exercises with Visual-Based Metaphor Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Halic University
Multiple Sclerosis
Body Awareness, Trunk Stability, and Arm Function in MS
The aim of this study is to investigate the relationship between body awareness, trunk stabilization, and upper extremity functionality in patients with Multiple Sclerosis (MS).
- Trial name
- NCT07151534
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Multiple Sclerosis, Pain Management
Cone Evasion Walk Test in Multiple Sclerosis
This cross-sectional methodological study aims to examine the test-retest reliability, intrasession reliability, and construct validity of the Cone Evasion Walk (CEW) Test in individuals diagnosed with Multiple Sclerosis (MS).
- Conditions
- Multiple Sclerosis, Pain Management, Function
- Trial name
- CEW-MS (NCT07786987)
- Testing
- Cone Evasion Walk Test and Clinical Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Spinal Cord Injury/Disorder, Stroke
Electrical Stimulation Exercise for Individuals With Lower Limb Paralysis
The purpose of this research study is to evaluate the effectiveness of an exercise training intervention (24-36 sessions) to improve muscle strength and endurance in the lower limbs of individuals with paralysis.
- Conditions
- Spinal Cord Injury/Disorder, Stroke, Multiple Sclerosis, Traumatic Brain Injury
- Trial name
- NCT07768761
- Testing
- Exercise with Electrical Stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Louis Stokes VA Medical Center
Multiple Sclerosis
EMG Biofeedback Training to Improve Balance in Individuals with Multiple Sclerosis
The goal of this clinical trial is to test the impact of a novel dual-task EMG Biofeedback training method for improving balance in individuals living with multiple sclerosis.
- Trial name
- MSBAL (NCT06461741)
- Testing
- Integrated Dual-task EMG Biofeedback Training (EMG-BF), Traditional Balance Exercise Training (BAL-EX)
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- McMaster University
Multiple Sclerosis
The Effect of Internal- or External-Focused Exercise Training, Administered in Conjunction With a Cognitive Task, on Walking, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis
This interventional clinical trial aims to investigate the effects of internal and external focus-based exercise training combined with cognitive dual-task training in individuals diagnosed with multiple sclerosis.
- Trial name
- NCT07507084
- Testing
- Internal Focus Dual-Task Training, External Focus Dual-Task Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kutahya Health Sciences University
MS (Multiple Sclerosis)
Dubousset Functional Test: an Investigation of Its Validity and Reliability in Individuals with Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune disease characterized by neuroinflammation and neurodegeneration in the central nervous system.
- Trial name
- NCT06849882
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Inonu University
Multiple Sclerosis, Mixed Reality
Validity and Reliability of Mixed Reality-Based Mobility Tests in Multiple Sclerosis
Multiple sclerosis (MS) is a demyelinating and neurodegenerative disease of the central nervous system, with common symptoms including muscle weakness, balance impairments, gait difficulties, and fatigue.
- Trial name
- NCT07361965
- Testing
- Clinical Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Selcuk University
Multiple Sclerosis
Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community
Cognitive impairments are common in multiple sclerosis (MS) diagnosed both at the onset and throughout the disease course. Poor cognitive abilities have been associated with poor outcomes such as higher levels of unemployment…
- Trial name
- NCT06608797
- Testing
- Learning and memory training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Effect of Dual-Task Training and Cognitive Rehabilitation in Individuals With Multiple Sclerosis.
The purpose of this study is to examine the effects of dual-task training and cognitive rehabilitation on gait, balance, fatigue and cognitive performance in individuals with multiple sclerosis.
- Trial name
- NCT06949696
- Testing
- Dual Task Training, Cognitive Rehabilitation, Conventionel Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Toros University
Multiple Sclerosis, Multiple Sclerosis-Relapsing-Remitting
Intermittent Hypoxia in Persons With Multiple Sclerosis
This study aims to understand the mechanisms of a novel intervention involving breathing short durations of low levels of oxygen for persons with multiple sclerosis (MS).
- Conditions
- Multiple Sclerosis, Multiple Sclerosis-Relapsing-Remitting, Multiple Sclerosis, Secondary Progressive
- Trial name
- NCT06276634
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Shirley Ryan AbilityLab
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Multiple Sclerosis
Local Vibration and Ankle Mobilization in Multiple Sclerosis
This study will investigate the effects of local vibration and ankle joint mobilization on muscle tone, proprioception, and balance in individuals with multiple sclerosis (MS).
- Trial name
- NCT07879950
- Testing
- Local Vibration, Ankle Joint Mobilization
- Volunteers
- 60 people
- Sponsor
- Gaziantep Islam Science and Technology University
Multiple Sclerosis, Inspiratory Muscle Training
Inspiratory Muscle Training in Individuals With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic disease affecting the central nervous system, characterized by inflammation, demyelination, and axonal degeneration, and primarily affects young adults.
- Trial name
- NCT07672535
- Testing
- High intensity interval IMT, Low intensity IMT, Conventional rehabilitation
- Volunteers
- 48 people
- Sponsor
- Istanbul University - Cerrahpasa
Multiple Sclerosis, Pilates Exercise
The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis
Objectives Objective 1: To determine the effects of a 16-week remotely delivered Pilates intervention on walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS.
- Conditions
- Multiple Sclerosis, Pilates Exercise, Walking, Balance
- Trial name
- MS (NCT07504120)
- Testing
- Pilates
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Multiple Sclerosis, High-intensity Interval Training
The Effects of High-Intensity Interval Training on Gait, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis
This study aims to comparatively investigate the effects of low-volume High-Intensity Interval Training (HIIT) versus Moderate-Intensity Continuous Training (MICT) on gait, balance, cognitive functions, and neurovascular…
- Conditions
- Multiple Sclerosis, High-intensity Interval Training, Gait, Balance
- Trial name
- HIIT-MS (NCT07578740)
- Testing
- Moderate-Intensity Continuous Training (MICT), High-Intensity Interval Training (HIIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Multiple Sclerosis
Effects of Torso Weighting on Muscle Activation During Balance Tests in Individuals With and Without Multiple Sclerosis
Rationale: The Balance-Based Torso-Weighting (BBTW) is a patented evaluation system that uses strategic placement of small or lightweight weights on the trunk to improve balance and stability.
- Trial name
- BBTW-MS (NCT06981013)
- Testing
- balance based torso weighting
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of St. Augustine for Health Sciences
Multiple Sclerosis
Evaluation of the Effect of Mental Imagery Training Combined With Modified Constraint-Induced Movement Therapy in Individuals With Multiple Sclerosis
This study aims to investigate the effects of mental imagery training combined with modified constraint-induced movement therapy in individuals with multiple sclerosis.
- Trial name
- NCT07899411
- Testing
- odified Constraint-Induced Movement Therapy + Mental Imagery Training, Modified Constraint-Induced Movement Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Hacettepe University