Clinical trials: Induction Anesthesia
Geriatric, General Anesthesia Induced Hypotension
What Causes Low Blood Pressure After Anesthesia in Older Adults Having Non-Heart Surgery ?
The purpose of this study is to identify risk factors contributing to post-induction hypotension in geriatric patients undergoing elective non-cardiac surgery under general anesthesia at Dr.
- Conditions
- Geriatric, General Anesthesia Induced Hypotension, Elective Surgery, Hypotension
- Trial name
- GERIHYPO (NCT07019805)
- Testing
- Standard General Anesthesia Induction Using Propofol, Fentanyl and Midazolam, Blood Pressure Continous Monitoring, syrnge pump for the anesthesia agent, and vasoconstrictor drug
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Post-induction Hypotension
Evaluation of the Relation Between Patient Fasting Time and the Occurrence of PIH (Post Induction Hypotension)
This monocentre prospective trial aims to evaluate the relationship between fasting time and the occurence of PIH (post-induction hypotension).
- Trial name
- NCT07785635
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Ostrava
General Anesthetic Drug Adverse Reaction
Effect of Tegileridine Versus Sufentanil as Analgesic Components on Opioid-Induced Cough During Anesthesia Induction
In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or Tegilerdine.
- Trial name
- NCT07323043
- Testing
- Tegilerdine, Sufentanil
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang
Anxiety, Surgery
Could Music be an Alternative to Sedation in Patients Treated Total Knee Arthroplasty With Regional Anesthesia?
Background: Anxiety is a common phenomenon in hospitalized patients. In order to reduce it during the surgical procedure, sedatives and anxiolytics are used, which can cause undesirable side effects for patients.
- Conditions
- Anxiety, Surgery, Drug Toxicity, Anesthesia
- Trial name
- NCT03882541
- Testing
- Music therapy, Sedation with midazolam
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de l'Anoia
Lower Extremity Fracture
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries.
- Trial name
- NCT03580889
- Testing
- Atropine, Glycopyrrolate, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Nepal
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary)
Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy
This study will evaluate whether quantitative pupillometry measurements can be used to identify children at risk for postoperative opioid-induced respiratory depression (OIRD) following tonsillectomy.
- Conditions
- Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
- Trial name
- NCT07573150
- Testing
- Infrared Pupillometry
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- NeurOptics Inc
Obese
The Effect of Mask Combined With High Flow Oxygen on Preoxygenation During Induction of General Anesthesia in Obese Patients
There is a risk of airway-related incidents during anaesthesia associated with obesity. High-flow nasal oxygen is advocated for perioperative preoxygenation in obese patients to reduce airway adverse reactions.
- Trial name
- NCT06562660
- Testing
- apnoeic
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Muscle Relaxant, General Anesthesia
Effect of Neostigmine on the Recovery of Rocuronium: A Comparison Between Partial and TOF Ratio-Based Dose
This study aimed to evaluate the effect of Neostigmine partial dose towards neuromuscular blockade of rocuronium
- Trial name
- NCT03058263
- Testing
- Dose of Neostigmine
- Where
- Indonesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Hypothermia
Temperature Changes During Induction of General Anesthesia in Pediatric Patients
We aim that uncovering patients during induction of general anesthesia does not decrease core body temperature in pediatric patients.
- Trial name
- NCT00710320
- Testing
- Covered and uncovered anesthesia induction
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cholecystectomy, Laparoscopic, Noise
The Effect of Noise Control During Anesthesia Induction in Laparoscopic Cholecystectomy Surgery
This study aims to determine the effects of active and passive noise control method and headphone usage and noise level during anesthesia induction in laparoscopic cholecystectomy surgery on hemodynamic parameters, pain, nausea…
- Conditions
- Cholecystectomy, Laparoscopic, Noise, Anesthesia Induction
- Trial name
- Anesth-noise (NCT06666686)
- Testing
- Active noise control headphone, Passive noise control headphone
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Anesthesia, Drug Effects
Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers
In imaging functional connectivity (FC) analyses of the resting brain, alterations of FC during unconsciousness have been reported.
- Trial name
- NCT02149927
- Testing
- Sevoflurane
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Anxiety, Decision Making
Impact of Anxiety on the Decision-making Processes of Anesthesiologists
Except for exaggerated situations in which aspiration risk seems obvious (or absent), the choice of a rapid sequence induction protocol for general anesthesia is often made under uncertainty, according to the individual…
- Conditions
- Anxiety, Decision Making, General Anesthesia
- Trial name
- DECIDINH (NCT05364801)
- Testing
- Survey
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Morphine Adverse Reaction
Intrathecal Dexamethasone and Atropine on Morphine Induced Post-operative Nausea and Vomiting on Caesarean Section
Pain is a major problem during the postoperative period and can be considered as a challenge for the anesthesiologist. Low dose intrathecal morphine is proven efficient as a mode to reduce postoperative pain.
- Trial name
- NCT05560542
- Testing
- Atropine and Dexamethasone
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anesthesia, General
Evaluation of a Closed-Loop Control System for Administering Patient-Specific Anesthesia
Numerous efforts have focused on the development of closed-loop systems to control anesthesia using the electrical activity of the brain (EEG) and EEG-based parameters as surrogate measures of anesthetic depth.
- Trial name
- NCT00683956
- Testing
- ReinLoop control software for patient-specific induction and maintenance of anesthesia, Propofol
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anesthesia Induction Ventilation
Safety and Efficacy of the Tao Facemask for Positive Pressure Ventilation in the Patients With Significantly Elevated BMIs
The Tao Mask is a new novel facemask for positive pressure ventilation which has recently been demonstrated (MUSC study Pro00047645) to have superior performance to our conventional (standard) positive pressure mask in a random…
- Trial name
- NCT03473366
- Testing
- Tao Mask, Standard Mask
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Intraoperative Complications, Postoperative Complications
Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.
The goal of this study is to investigate the effect of depth of neuromuscular block (NMB) on global and regional (dependent versus nondependent) respiratory mechanics during laparoscopic surgery.
- Conditions
- Intraoperative Complications, Postoperative Complications, Laparoscopy, Surgical Complications From General Anesthesia
- Trial name
- NCT02025075
- Testing
- Rocuronium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pediatric Population, Preoperative Anxiety
Comparing the Effectiveness of Virtual Reality in Paediatric Patients
To the best of our knowledge,the investigators found only a study using VR in reducing preoperative anxiety in paediatric population.
- Trial name
- NCT06044753
- Testing
- Virtual Reality Headset
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Active Emergence From General Anesthesia
EEG Studies of IV Methylphenidate-Induced Emergence From Anesthesia
The aim of this study is to test the hypothesis that methylphenidate actively induces emergence from propofol and sevoflurane general anesthesia in healthy volunteers.
- Trial name
- NCT02429076
- Testing
- IV methylphenidate, Sevoflurane, Propofol
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cannulation, Sevoflurane Induction
Determination of Optimum Time for Intravenous Cannulation in Children With Dexmedetomidine Premedication
Inhalational induction with sevoflurane, nitrous oxide, and oxygen is accepted as a safe technique to avoid any movement during intravenous cannulation in children.
- Conditions
- Cannulation, Sevoflurane Induction, Dexmedetomidine
- Trial name
- NCT05139212
- Testing
- Optimum time for intravenous cannulation in children premedicated with dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Hypoglycemia; Iatrogenic, Anesthesia
Fasting Induced Hypoglycaemia in Anaesthetised Paediatric Patients
Fasting is a requirement to safely anesthetise patients referred for elective procedure, using the traditional 6/4/2 rule (6h for solid food or formula milk, 4h for breast milk and 2h for clear fluids), applied to all patients…
- Conditions
- Hypoglycemia; Iatrogenic, Anesthesia, Pediatrics
- Trial name
- FIGS (NCT07259629)
- Where
- 24 sites in United Kingdom
- Volunteers
- 2,902 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust