Clinical trials: Induction of Labor
Preeclampsia
Proof-of-Concept Trial on Selective Removal of sFlt-1 in Pregnant Women With Preeclampsia Via Apheresis
This clinical investigation is a medical device trial to examine the safety and efficacy of TheraSorb sFlt-1 adsorber treatment of pregnant patients with preeclampsia.
- Trial name
- SAVE (NCT02923206)
- Testing
- TheraSorb sFlt-1 adsorber
- Where
- 4 sites in Germany, United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Miltenyi Biomedicine GmbH
Labor Induction, Cervical Ripening
Trial of Foley Catheter With and Without Extra-Amniotic Saline Infusion for Labor Induction
The purpose of this study is to compare the efficacy of a transcervical Foley catheter with and without extra-amniotic saline infusion (EASI) for priming the cervix for labor.
- Trial name
- FOLEYEASI (NCT00442663)
- Testing
- Transcervical Foley Catheter, Transcervical Foley Catheter with an EASI
- Where
- 4 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Induction of Labor
Castror Oil for Labor Induction in Women With Previous Cesarean Section
Nowadays, more and more women embark on pregnancy with previous Caesarean scar. One in five pregnancies requires induction of labour.
- Trial name
- NCT03958981
- Testing
- Castor Oil
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Induction of Labor
Stepwise Labor Induction Following Failure of Prostaglandin Vaginal Insert for Labor Induction
Induction of labor is one of the most common obstetrical medical procedures performed today. Iatrogenic stimulation of uterine contractions prior to the onset of spontaneous labor is undertaken for various maternal and fetal…
- Trial name
- NCT02684305
- Testing
- Administration of Propess, balloon, Intravenous oxytocin infusion
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pregnancy Overdue - Week 41+6
Can Acupuncture be Used as Preparation for Induction of Labour
The purpose of the study is to evaluate whether acupuncture can be used to ripen cervix before medicinal induction of labor or even be used as method for induction, and thereby eliminating other and more potentially harmful…
- Trial name
- NCT00245752
- Testing
- acupuncture
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital Skejby
Epidural, Labor Pain
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Labour pain can be intensified for labour inductions and women undergoing inductions often have earlier and more frequent requests for analgesia.
- Conditions
- Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn, Obstetric Anesthesia Problems
- Trial name
- NCT04011098
- Testing
- Epidural Fentanyl Bolus, Standard Epidural Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Accident Caused by Snow Avalanche
Work of Breathing Under Extreme Hypercapnia Induced by Ventilation Insufficiency
The aim of the study is to investigate Work of Breathing of a person in simulated avalanche snow and consequent use of the measured data for judging which one of three simulated scenarios are alike while increasing hypercapnia in…
- Trial name
- NCT04835545
- Testing
- extreme hypercapnia induced by ventilation insufficiency
- Where
- Czechia
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Job Satisfaction, Work Performance
Life Skills Training Workplace Prevention Program
A workplace health promotion intervention for youth age 16-24
- Conditions
- Job Satisfaction, Work Performance, Health Care Utilization, Depression Symptoms
- Trial name
- LST-WP (NCT06745739)
- Testing
- Life Skills Training Workplace Prevention Program
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- National Health Promotion Associates, Inc.
Macrosomia, Induction of Labor
Induction of Labor Versus Expectant Management of Large for Gestational Age/Macrosomic Babies at Term. A Multi-center Trial
The equipoise whether to Induce pregnant women with suspected large for gestational babies or suspected macrosomia babies at term pregnancy is not solved yet.
- Conditions
- Macrosomia, Induction of Labor, Expectant Management, Shoulder Dystocia
- Trial name
- IOLEMMT (NCT02315820)
- Testing
- Induction of labor group (Group I)
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Infant, Newborn, Infant, Low Birth Weight
Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia
This study tested whether Neonatal Intensive Care Unit (NICU) teams trained in benchmarking -- comparing care practices between different NICUs to see which practices prevent bronchopulmonary dysplasia (BPD) -- and quality…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- Benchmarking (NCT00067613)
- Testing
- Benchmarking Management Practices, Standard Management Practices
- Where
- 17 sites in United States
- Volunteers
- 4,095 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Cardiovascular Diseases, Diabetes
Fit After Baby: Increasing Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease
This study plans to learn more about how to increase postpartum weight loss and how to decrease risk factors for postpartum women at increased risk for diabetes and heart disease.
- Conditions
- Cardiovascular Diseases, Diabetes, Gestational Diabetes, Preeclampsia
- Trial name
- FAB (NCT03215173)
- Testing
- Fit After Baby, Text4Baby Control Group
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pre-Eclampsia
qMOLI- A Qualitative Assessment of Misoprostol or Oxytocin for Labour Induction
Q MOLI is an alongside qualitative study, for the 'Misoprostol or Oxytocin for Labour Induction' (MOLI) pragmatic, open-label, randomised controlled trial, comparing a misoprostol/misoprostol regime vs the standard…
- Trial name
- qMOLI (NCT04037683)
- Testing
- Misoprostol Oral Tablet, Oxytocin
- Where
- India
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Labor for Induction Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women scheduled for an induction of labor, with whom analgesia is maintained with a combined spinal…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982851
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Duration of Labor
Does Oral Propranolol Accelerate Labor Induction/Augmentation With Oxytocin in Nulliparous Women in Abakaliki?
Labour is usually physiologic, spontaneous and progressive, but occasionally, there may be the need for induction or augmentation of labour especially in nulliparous women, who are at increased risk of dysfunctional labour.
- Trial name
- NCT05251610
- Testing
- 20mg oral propranolol and oxytocin, Oxytocin only
- Where
- Nigeria
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Failed Induction of Labor
Modifying Cervical Bishop Scoring System
To have an early more precise way to predict failed induction in patients undergoing elective termination of pregnancy \& those more likely to undergo caesarian section,this will Spare patients with decreased chances of favorable…
- Trial name
- NCT02314260
- Testing
- bishop score calculation, Trans-vaginal ultrasound, Modified bishop score calculation
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Premature Rupture of Fetal Membranes
Oxytocin vs. Prostaglandin for Induction of Labor in Primiparas With Prelabor Rupture of Membrane and Low Bishop
The purpose of the study is to compare between oxytocin to prostaglandin (PGE2), regarding time from induction of labor (IOL) to delivery among primiparas at term with prelabor rupture of membrane (PROM) and an unfavorable cervix.
- Trial name
- NCT02801227
- Testing
- Oxytocin, Prostaglandin E2
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Premature Rupture of Membrane, Induction of Labor Affected Fetus / Newborn
PROMMO Trial: Oral Misoprostol vs IV Oxytocin
This is a prospective, randomized trial looking at the ideal method of labor induction for women with prelabor rupture of membranes and an unfavorable cervical Bishop score.
- Trial name
- PROMMO (NCT04478942)
- Testing
- Misoprostol Oral Product, Intravenous Oxytocin
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Labor, Induced, Labor, Obstetric
Prediction of Spontaneous Onset of Labor at Term
The study intends to develop a predictive model of spontaneous onset of labor between 39 and 41 weeks of pregnancy in women carrying singletons and without indication of delivery before this date.
- Conditions
- Labor, Induced, Labor, Obstetric, Labor Onset, Predictive Model
- Trial name
- PREDICT (NCT05109247)
- Where
- 3 sites in Switzerland
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Gestational Hypertension, Mild Pre-eclampsia
Labor Characteristics and Outcomes in Women With Gestational Hypertension or Preeclampsia Who Underwent Labor Induction
Comparison of Labor Characteristics and Maternal-Neonatal Outcomes in Induced Labor Between Women with Gestational Hypertension/Mild Preeclampsia and Normotensive Controls
- Trial name
- NCT06907576
- Where
- China
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Cervical Ripening and Induction of Labor
Comparison Between Vaginal Misoprostol Gel and Oral Misoprostol Solution in Induction of Labor
The goal of this clinical trial is to study the efficacy of vaginal versus oral misoprostol solution in cervical ripening for induction of labor.
- Trial name
- NCT06874049
- Testing
- Vaginal misoprostol, Oral misoprostol solution (OMS)
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hagar Muhammad Abdulfattah Muhammad