Clinical trials: Inferior Alveolar Nerve Block
Symptomatic Irreversible Pulpitis
Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block.
The purpose of this study is to see how preoperative oral diclofenac sodium, piroxicam, and tramadol affects inferior alveolar nerve block efficacy during root canal treatment of mandibular molars with symptomatic irreversible…
- Trial name
- NCT05488925
- Testing
- Vitamin E, Diclofenac Sodium, Piroxicam
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Farjad Zafar
Dental Caries
Effectiveness of the Intraligamentary Anesthesia and Inferior Alveolar Nerve Block on Pain During Dental Treatment
Objective: To compare the effectiveness and complications of intraligamentary anesthesia (ILA) with conventional inferior alveolar nerve block (IANB) during injection and dental treatment of mandibular posterior teeth.
- Trial name
- NCT04563351
- Testing
- local anaesthetic techniques
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Acute Pulpitis
Pain Measured by NRS and EEG in Acute Pulpitis
The aim of the proposed study is to investigate and comprehensively understand pain perception in patients diagnosed with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB).
- Trial name
- NCT06526572
- Testing
- Brain wave analysis using electroencephalography (EEG)., Numerical rate Scale (NRS)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cleveland Dental Institute
Symptomatic Irreversible Pulpitis
Volume Increase Versus Supplemental 4% Articaine Buccal Infiltration on Mepivacaine Inferior Alveolar Nerve Block Success
To assess the anesthetic success of inferior alveolar nerve block (IANB), intraoperative pain intensity and need for supplemental anesthesia on administration of 1.8ml or 3.6ml 2% mepivacaine IANB, or 1.8ml 2% mepivacaine IANB…
- Trial name
- NCT05238727
- Testing
- 1.8 ml mepivacaine hydrochloride, 3.6 ml mepivacaine hydrochloride, 1.8 ml mepivacaine hydrochloride IANB plus 1.8 ml articaine hydrochloride BI
- Volunteers
- 75 people
- Sponsor
- Cairo University
Anaesthesia, Anxiety
Impact of AR Glasses on Children's Behavior During Dental Nerve Blocks
The aim of this study is to evaluate the effectiveness of augmented reality glasses in managing pain, anxiety, and behavior in pediatric patients during inferior alveolar nerve block Group A (Control group): inferior alveolar…
- Trial name
- NCT06724341
- Testing
- Distraction
- Where
- Syria
- Volunteers
- 108 people
- Sponsor
- Damascus University
Molar, Impacted Teeth
Analgesic Effects of Extraoral Ultrasound Block of Mandibular Nerve for the Extraction of Lower Third Molars
This is a study about the dynamics and effects of different types of blocks (intraoral conduction anesthesia of the alveolar nerve and extraoral US block of the mandibular nerve) for extraction of lower third molars.
- Trial name
- NCT06009302
- Testing
- US guided block of mandibular nerve, Intraoral block of lower alveolar nerve
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- Varazdin General Hospital
Postoperative Pain, Mandible Fracture
Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery
Pain following open reduction of mandibular fractures is the most reported complaint during the first 24 post-operative hours. The goal of this clinical trial is to evaluate the impact of inferior alveolar nerve block with…
- Conditions
- Postoperative Pain, Mandible Fracture, Analgesia, Anesthesia, Local
- Trial name
- NCT06243263
- Testing
- Bupivacain
- Where
- 2 sites in Tunisia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Anaesthesia
Intraosseous Anesthesia Versus Mandibular Nerve Block in Children
The aim of the current study is to compare a new computerized intra-osseous injection system to the conventional inferior alveolar nerve block in children
- Trial name
- NCT05193487
- Testing
- inferior alveolar nerve block, intra-osseous mandibular anaesthesia
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Restorative Dental Treatment by Buccal Infiltration Anaesthesia
Clinical Evaluation of Anaesthetic Efficacy of 4% Articaine Buccal Infiltration Versus Inferior Alveolar Nerve Block
Clinical evaluation of anaesthetic efficacy of 4% articaine buccal infiltration versus inferior alveolar nerve block during restorative dental treatment in mandibular first permanent molars
- Trial name
- NCT06353815
- Testing
- 4% articaine infiltration
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Anxiety, Pain
Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this studio will be to evaluate the effectiveness of "Hands/Eyes/mouth" behavior management technique versus a conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02591797
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Cardenal Herrera University
Inferior Alveolar Nerve Block in Children
Clinical Success of 12 mm Needle IANB in Children
This prospective single-arm pilot study will evaluate the clinical success of an inferior alveolar nerve block performed using a 12 mm 30-gauge extra-short dental needle in children aged 4 to 12 years.
- Trial name
- NCT07791082
- Testing
- 12 mm 30-Gauge Extra-Short Dental Needle
- Where
- Egypt
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pulpitis - Irreversible
SCN9A Gene Expression and Inflammatory Cytokines
Voltage-gated sodium channels, especially Nav1.7 encoded by the SCN9A gene, are key regulators of nociceptive transmission. Upregulation of SCN9A has been associated with increased neuronal excitability and heightened pain…
- Trial name
- Gene Expressio (NCT07532200)
- Testing
- Inferior Alveolar Nerve Block
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Local Infiltration
Hyaluronidase Enzymes and Local Anesthesia
For both groups, local anaesthesia will be administered by one single surgeon and the extraction will be performed by another single surgeon across all subjects.
- Trial name
- NCT06980363
- Testing
- traditional inferior alveolar nerve block by articaine, hyaluronidase plus articain buccal infilteration
- Volunteers
- 20 people
- Sponsor
- Fayoum University
Pulpitis
Comparative Evaluation of Pulpal Anaesthetic Efficacy of Different Anaesthetic Solutions for Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis
Pulpal and periapical inflammation and infection can cause tissue pH in the affected region to be lowered which results in less penetration of anesthetic solution in the nerve membrane and hence delays the onset of anesthesia.
- Trial name
- NCT05239078
- Testing
- local anaesthetic injection
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dr. Vivek Aggarwal
Pulpitis
Anesthetic Efficacy of 1,8mL and 3,6mL of Articaine in Inferior Alveolar Nerve Block in Irreversible Pulpitis
Ninety patients with irreversible pulpitis diagnostic will participate in this clinical study. The participants will be divided into 2 groups of 45 patients, who will receive the inferior alveolar nerve block injections of 1.8 mL…
- Trial name
- Volumes (NCT02422823)
- Testing
- Articaine, Epinephrine
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Isabel Peixoto Tortamano
Local Anesthesia
Effect of Lidocaine With Magnesium Sulfate on the Success of the Inferior Alveolar Nerve Block
68 healthy patients pulpitis and requiring root canal therapy are selected. . Sampling was done in a simple and non-experimental way from a dental clinic in Isfahan, and then the samples were randomly assigned to one of the two…
- Trial name
- NCT03262857
- Testing
- use of magnesium sulfate with lidocaine in inferior alveolar nerve block
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Symptomatic Irreversible Pulpitis (SIP)
The Effect of Electroacupuncture (EA) on the Success of Inferior Alveolar Nerve Block (IANB) and Post-operative Pain Relief in Mandibular Molar With Symptomatic Irreversible Pulpitis (SIP) Among Malaysians: A Study Protocol for Randomized Double-Blinded Clinical Pilot Study
Acupuncture is recognized for its pain relief effect. Electroacupuncture(EA) is a form of acupuncture where electric current is passed between pairs of acupuncture needles in order to achieve therapeutic effect.
- Trial name
- NCT04804761
- Testing
- Electroacupuncture
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- IMU University, Malaysia
Dental Pain
Dental Block for Pain Relief in ED Dental Pain Patients
This will be a prospective, observational cohort study assessing immediate pain relief from dental block in ED patients presenting with dental pain. The study will be conducted in the Community Regional Medical Center ED.
- Trial name
- NCT05351099
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- University of California, San Francisco
Greater Palatine Nerve Block, Inferior Alveolar Nerve Block
Evaluation of Use of Ultrasound for Greater Palatine Nerve Block and Inferior Alveolar Nerve Blocks: An Open Label Feasibility Study
Dental anesthesia is routinely performed based on anatomical landmarks which can be variable leading to repeated injections and failure.
- Trial name
- NCT01870232
- Testing
- US guided block
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's