Clinical trials: Infertility (IVF Patients)
AMH Levels, Inhibin B Levels
Evaluation of Anti-mullerian Hormone Levels as Predictive of IVF Outcomes in Women Over 38 Years Old
The present study is designed to evaluate the basal serum levels of anti-mullerian hormone (AMH) and inhibin B as early predictors of ovarian response, implantation rate, and pregnancy rate in women 38 years old or older that are…
- Conditions
- AMH Levels, Inhibin B Levels, IVF Patients Over 38 Years Old
- Trial name
- NCT01219387
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility, Poor Ovarian Reserve
Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score
Patients will have ovarian PRP treatments and embryo development will be observed using time-lapse imaging and AI software.
- Conditions
- Infertility, Poor Ovarian Reserve, Embryo Growth Disorder, in Vitro Fertilization
- Trial name
- NCT07020546
- Testing
- Ovarian Platelet-rich plasma (PRP) injections
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Generation Next Fertility
Infertility, Subfertility
Comparison of Transfers of Fresh and Thawed Embryos in Patients With Prior Failed Embryo Transfer Cycles
This study seeks to determine if patients with a history of failed fresh embryo transfer(s) will have increased success rates with embryo cryopreservation and subsequent thawed embryo transfer when compared to fresh embryo…
- Trial name
- NCT00736177
- Testing
- Embryo cryopreservation, Fresh embryo transfer
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Infertility (IVF Patients)
An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera
A clinical trial will determine the effectiveness of using the Opt-IVF decision support tool for each patient's personalized and optimal drug dosage profile in the United States.
- Trial name
- NCT07148999
- Testing
- Opt-IVF, Control
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Urmila DIwekar
Infertility, Female, IVF
RCT to Assess the Impact of Microbiome Status in Infertile IVF Patients at Their First IVF/ICSI Cycle
Although the endometrium has been traditionally considered free of bacteria, recent studies have documented the presence of an endometrial microbiome.
- Trial name
- NCT04686357
- Testing
- EMMA/ALICE
- Volunteers
- 1,018 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Infertility
The Influence of Estradiol Supplementation During the Luteal in Patients Undergoing IVF Treatment
To evaluate whether treatment with Estradiol supplementation during the luteal phase improves IVF outcomes Patients undergoing IVF treatment with controlled ovarian hyperstimulation using a GnRH analog will receive 4 mg estradiol…
- Trial name
- NCT00490308
- Testing
- Treatment with estradiol valerate
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Infertility
Endometrial Sampling (Pipelle)in IVF Patients
A prospective cross-over randomized study aimed to test the hypothesis that local injury of the endometrium increases the implantation rate in the successive cycle.
- Trial name
- NCT00411021
- Testing
- Pipelle (Endometrial Sampling)
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility
Comparison Between hCG and GnRH Agonist for Ovulation Induction in Patients With High Response to IVF Drugs
hCG and GnRH agonist can be used to induce final oocyte maturation and ovulation in IVF cycles. These two approaches will be compared in this study in terms of pregnancy rates and embryological data using patients with…
- Trial name
- NCT00415792
- Testing
- Arvekap, Pregnyl
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eugonia
Polycystic Ovary Syndrome, IVF
Follicular Fluid Raman Shifts and IVF Outcomes
This study intends to collect about 150 cases of follicular fluid samples from PCOS and non-PCOS infertility patients undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles (in clinical…
- Trial name
- NCT04838535
- Testing
- Raman spectrum
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility Female
IVM for Patients With Low Ovarian Response. Does it Improve IVFoutcomes and Does it Improve the Following IVF Cycle?
Poor ovarian response (POR) is one of the major therapeutic challenges in in vitro fertilization. Several therapeutic approaches for POR have been explored; yet, a single effective strategy has not yet been established.
- Trial name
- NCT02498210
- Testing
- In Vitro Maturation Procedure
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Asthenozoospermia, Oligospermia
Myo-inositol on Human Semen Parameters
Many clinical evidences suggest that Myo-inositol plays a crucial role in human reproduction. Also, it was shown that Myo-inositol concentration in the seminiferous tubules was higher than in serum, and interestingly it was…
- Trial name
- NCT01828710
- Testing
- Myo-inositol normospermic, Myo-inositol OAT, Folic Acid normospermic
- Where
- Italy
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Infertility (IVF Patients), Infertile Females or Females with Ovarian Insufficiency
Evaluation of Pregnancy Outcome with Usage of Drug-free In-vitro Activation of Follicles Ovary
This study is the pilot study to evaluate the effect of Drug-free in vitro activation to improve the outcomes of IVF in poor responder women
- Trial name
- NCT06769789
- Testing
- Drug free invitro activation Ovary
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Malihe Mahmoudinia
Infertility
Influence of Ethnical Differences on the Egg Cell Collected in Patients Undergoing Fertility Treatment
Investigators wants to analyze the differences considering the country of origin, ethnicity, characteristics, reproductive history and habits of participants undergoing in vitro fertilization (IVF) / intracytoplasmic sperm…
- Trial name
- NCT03927417
- Where
- United Arab Emirates
- Volunteers
- 1,117 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
Optimizing Patient Analgesic Experience During IVF
This study is for patients undergoing In Vitro Fertilization (IVF). The investigators are studying the best way to control pain during the egg retrieval process.
- Trial name
- NCT01814657
- Testing
- Lidocaine hydrochloride (HCl) 1% solution, Sterile Normal Saline%
- Where
- Canada
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Infertility Primary
The Aim of This Study is to Determine if Oocyte Sorting for Group Culture Using an Artificial Intelligence Image Analysis Tool (MagentaTM) Increases the Usable Blastocyst Yield and Subsequent Pregnancy in Patients Undergoing IVF
The aim of this study is to determine if oocyte sorting for group culture using an artificial intelligence image analysis tool (MagentaTM) increases the usable blastocyst yield and subsequent pregnancy in patients undergoing IVF.
- Trial name
- NiOS (NCT06521372)
- Testing
- Magenta AI image analysis tool
- Where
- 3 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ovation Fertility
Female Infertility Due to Advanced Maternal Age
Mitochondrial Energy Production in ART (Assisted Reproductive Technology )
Oocyte maturation requires a lot of energy, which is provided by the mitochondria via the synthesis of ATP. The majority of patients with advanced maternal age (AMA) have poor egg quality.
- Trial name
- Mitenergy (NCT02727400)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Infertility
Ultrashort GnRH Agonist/Antagonist Versus GnRH Antagonist IVF
The purpose of this study is to evaluate the appropriate controlled ovarian hyperstimulation (COH) protocol in good prognosis patients undergoing IVF treatment.
- Trial name
- NCT02173977
- Testing
- ARM A- Agonist/Antagonist protocol, ARM B- Antagonist protocol
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Recurrent Implantation Failure
Platelet Rich Plasma and Recurrent Implantation Failure
This study is a randomized controlled clinical trial to compare the pregnancy outcomes of infertile women with recurrent implantation failure.
- Trial name
- NCT03996837
- Testing
- Intra uterine infusion of platelet rich plasma
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Polycystic Ovary Syndrome, Infertility
Progesterone Primed Ovarian Stimulation Protocol Versus Antagonist Protocol for PCO Patient
this study is designed to compare the Progesterone primed ovarian stimulation protocol versus the antagonist protocol as a method to stimulate PCO patients in ICSI cycles to decrease cost and decrease OHSS.
- Conditions
- Polycystic Ovary Syndrome, Infertility, IVF
- Trial name
- NCT05847660
- Testing
- Progesterone antagonist, conventional antagonist protocol
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Infertility Assisted Reproductive Technology
fertiShare Evaluation
Sharing bad news (SBN) is a daily challenge for fertility staff and patients. Bad news happens at all stages of fertility care and includes e.g., diagnosing infertility, reporting unexpected, repeated, or definitive treatment…
- Trial name
- NCT06587360
- Testing
- fertiShare intervention - sharing bad news eLearning course, fertiShare control - basic communication skills eLearning course
- Where
- 5 sites in United Kingdom
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Cardiff University