Clinical trials: Infertility Unexplained
Infertility, Infertility, Female
Assessment of Ovarian Reserve Tests in Unexplained Infertile Women
IN UNEXPLAINED INFERTILITY IN WOMEN ,OVARY RESERVE IS BORDERLINE IF ASSESSED USING HIGH-SENSITIVE TESTS.
- Trial name
- NCT02127944
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Infertility, Male, Infertility Unexplained
Using of Testes Shocker in Improving the Spermatogenesis and Sperms Activity
Infertility was reported in approximately 15% of all heterozygous couples, with male factor accounting for nearly half the cases.
- Conditions
- Infertility, Male, Infertility Unexplained, Infertility Due to Complete Spermatogenic Arrest, Oligospermia
- Trial name
- NCT05506722
- Testing
- Testes shocker
- Where
- Iraq
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Infertility
Incidence of Early Pregnancy Loss in Patients With Unexplained Infertility
Unexplained fertility could be partly caused by a higher incidence of early pregnancy loss in this group. 65 women with unexplained infertility and 65 healthy controls will collect daily urine samples form the luteal phase.
- Trial name
- UNEXPLAINED (NCT01015690)
- Where
- Netherlands
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Male Infertility
CMV IGG Antibodies in Semen as a Predictor for Blood Testis Barrier Damage
To assess whether the presence of Cytomegalovirus (CMV) Immunoglobulin G (IGG) antibodies in semen is a reliable predictor of male subfertility or infertility.
- Trial name
- NCT05302856
- Testing
- Blood test (CMV IGG, Anti sperm antibody, Testosterone levels)
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Pregnancy
The Benefits of Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) in Couples With Unexplained Infertility
The (motile sperm organelle morphology examination) MSOME allows the detection of sperm vacuoles that seems to be related to sperm DNA damage.
- Trial name
- NCT01729533
- Testing
- ICSI, IMSI
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sapientiae Institute
Infertility
In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization
Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation…
- Trial name
- IVM vs IVF (NCT00867763)
- Testing
- In vitro maturation and in vitro fertilization, Low doses of gonadotropin stimulation.
- Where
- 2 sites in United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Batzofin Fertility Services
Infertility, Male Factor
FemaSeed LOCAL Artificial Insemination Trial
Brief Summary: The objectives of the trial are to evaluate the safety and effectiveness of the FemaSeed Localized Directional Insemination for artificial insemination, now known as the FemaSeed Intratubal Insemination since FDA…
- Trial name
- LOCAL (NCT04968847)
- Testing
- FemaSeed Localized Directional Insemination
- Where
- 18 sites in United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Femasys Inc.
Polycystic Ovary Syndrome, Infertility, Female
Effect of Nitric Oxide Donors on Uterine and Subendometrial Blood Flow in Patients With Unexplained Infertility
The purpose of the study to evaluate effect of nitroglycerin trans-dermal patches on uterine and sub-endometrial blood flow in women with unexplained infertility.
- Trial name
- NCT03481582
- Testing
- Nitroglycerin, Three dimensional power doppler
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries, Female Infertility
Relationship Between Oral Health Status and Unexplained Female Infertility in Turkish Population
Periodontal diseases and dental caries are initiated by a pathogenic biofilm, in a susceptible host, affecting the tooth periodontium and hard tissues. Its possible association with many biologic systems has been studied.
- Trial name
- NCT03575494
- Testing
- Intraoral and Radiographic Dental Examination
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Infertility
Serum Amyloid A in Women With Unexplained Infertility
High follicular fluid amyloid A level is associated with reduced pregnancy rate. The aim of this study was to find an association between serum level of amyloid A and unexplained infertility.
- Trial name
- NCT03918200
- Testing
- Serum amyloid A level
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Infertility Unexplained, Infertility, Male
Comparison of the Effect of Microchip and Density Gradient Methods in Intrauterine Insemination Cycles
Microfluidic chips are one of the methods of sperm separation to eliminate DNA fragmentation in sperm. It is thought that the separation of sperm by centrifugation in the classical gradient density (Percoll) method used in sperm…
- Trial name
- NCT04144244
- Testing
- MicroFluidic Sperm Sorting Chips, Gradient-Density Centrifugation
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Unexplained Infertility
Varicocelectomy in Patients With Clinical Varicocele and Unexplained Infertility
This study was conducted to assess the efficacy of varicocelectomy in unexplained male infertility with clinical varicocele The primary objective was to assess the pregnancy outcomes in these group.
- Trial name
- NCT06491251
- Testing
- Bilateral Subinguinal microscopic varicocelectomy
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Infertility, Female
Anti-Helicobacter Pylori Antibodies (IgG) in Serum of Women With Unexplained Infertility
Prevalence of anti-H.pylori IgG in serum of women with unexplained infertility and comparing that with it's prevalence in fertile women.
- Trial name
- NCT02684604
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Unexplained Infertility, Polycystic Ovarian Syndrome
Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT
The main purpose of this study is to test the effectiveness of nimodipine in preventing a luteinizing hormone (LH) surge in women undergoing ovulation induction with clomiphene citrate.
- Conditions
- Unexplained Infertility, Polycystic Ovarian Syndrome, Anovulatory
- Trial name
- NIMO (NCT01672801)
- Testing
- Nimodipine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility, Female
Infections and Unexplained Infertility
1. Background: In women, unexplained infertility has been associated with a range of cellular and molecular defects in the endometrium, adverse immune responses and immunological factors.
- Trial name
- NCT03581617
- Testing
- NK cell analysis, Herpesvirus detection, sHLA-G analysis
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Infertility, Unexplained Infertility
Uterine Scratching in Intra-Uterine Insemination
This study will evaluate the potential benefits of uterine injury during the follicular phase of an intra-uterine insemination cycle on the rate of ongoing pregnancy during the first trimester ultrasound.
- Trial name
- NCT03828786
- Testing
- Endometrial scratching
- Where
- Canada
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Clinique Ovo
Infertility Unexplained
Comparison of Recombinant Follicle Stimulating Hormone and the Combination of Recombinant Follicle Stimulating Hormone With Clomiphene Citrate in Stimulated Intrauterine Insemination Cycles
The aim of study is to evaluate the results of two different protocols for ovulation induction during IUI cycles. All patients undergo IUI cycles are randomly divided in to two groups.
- Trial name
- NCT05670795
- Testing
- Recombinant Follicle Stimulating Hormone, Recombinant Follicle Stimulating Hormone and Clomiphene Citrate
- Where
- Turkey (Türkiye)
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Infertility, Female, AMH
AMHR2 Polymorphism in Blood and Granulosa Cells in Unexplained Infertility
There are various known parameters for assessing ovarian reserve, including ovarian volume, antral follicle count, follicle stimulating hormone (FSH) and Inhibin B at the beginning of the menstrual cycle, as well as…
- Conditions
- Infertility, Female, AMH, IVF
- Trial name
- NCT05592730
- Testing
- AMHR2 polymorphism in blood, AMHR2 polymorphism in granulosa cell
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Infertility
Double and Single Intrauterine Insemination In Controlled Ovarian Stimulation (COH) Cycles With Multifollicular Development
Our hypothesis is double insemination will improve pregnancy rates in coh cycles with more than one dominant follicles (>16mm).
- Trial name
- NCT00993902
- Testing
- Intrauterine insemination (single), Double intrauterine insemination
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Baskent University
Atopics, Unexplained Infertility
Unexplained Infertility Among Asthmatic and Atopic Patients
Unexplained infertility is defined as the lack of thec ability to become pregnant during the first year, although the periods of the woman, the semen from the man and the laparoscopic findings are normal.
- Trial name
- NCT01788735
- Where
- Denmark
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- Elisabeth Juul Gade